Comparative efficacy of the modified minimally invasive “Parachute Technique” vs. the intermuscular GAP Approach in proximal humeral fracture management: a prospective study by Jia Jia Wei, Jia Jia Wei, Jun Li, Tao Chen, Hong Chi Yi, Wen Tao Zhao, Tian Tian, Jian Wei Wang

“…This study compares the Modified Minimally Invasive Parachute Technique and the Intermuscular Gap Approach in the management of displaced PHFs.ObjectiveTo compare clinical outcomes, including surgical efficiency, complication rates, functional recovery, and radiographic healing, between the two surgical techniques.MethodsA total of 40 patients aged 60 or older with displaced two- or three-part PHFs were randomized into two groups (n = 20 per group). …”
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Identification of subgroups of early-stage mycosis fungoides patients with increased itch and impaired quality of life by Julia Nenonen, Anna H. Winther, Anna H. Winther, Pontus Jonsson, Pontus Jonsson, Lina U. Ivert, Lina U. Ivert, Hanna Brauner, Hanna Brauner

“…This single center study investigated associations between QoL/itch/depressive symptoms and clinical phenotypes in patients with CTCL with particular focus on early MF-stages.MethodsPatients were included during routine dermatological care. …”
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Hyperreflective focuses as a biomarker of multiple sclerosis progression by A. Zh. Fursova, M. Y. Zubkova, M. A. Vasilyeva, Y. A. Gamza, A. S. Derbeneva, I. F. Nikulich, N. A. Malkova, A. I. Prokaeva, P. N. Pozdnyakova

“…Purpose: to identify the intraretinal hyperreflective foci (HRF), their specific characteristics, localization features and correlations with the duration of the disease, type of course and previous episodes of optic neuritis (ON) in multiple sclerosis (MS) patients using a high-resolution OCT scanning protocol. Materials and methods. The study included 160 patients (318 eyes) divided into 8 groups, i.e. …”
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Feasibility and safety of transvaginal natural orifice transluminal endoscopic surgery (V-NOTES) panhysterectomy: a polycentric retrospective study by Panlian Qian, Weimin Chen, Bin Su, Yao Chen, Wulin Shan, Huimin Tang, Weiwei Wei, Huihui Wang, Bairong Xia, Jiming Chen

“…Abstract Objectives To investigate the feasibility and safety of Transvaginal Natural Orifice Transluminal Endoscopic Surgery (V-NOTES) panhysterectomy. Methods A retrospective analysis was conducted on the data of 75 patients who underwent panhysterectomy for hysteromyoma in the Department of Obstetrics and Gynecology of Tongxiang Maternal and Child Health Hospital; Department of Gynecology, The Affiliated Changzhou Second People's Hospital of Nanjing Medical University and Department of Gynecology, The First Affiliated Hospital of USTC from June 2019 to June 2020. …”
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Outcomes of arthroscopic one-stage repair and reconstruction of Schenck II–IV knee dislocations with multiple ligament injuries: a single-center study by Shengwen Xiang, Zhen Hu, Zihao Ren, Guangqing Cai, Zhijiang Ao, Weiguo Hu, Yangbo Liu, Xing Li, Licheng Wei

“…Abstract Objective To evaluate the outcomes of arthroscopic one-stage repair and reconstruction of Schenck II–IV knee dislocations with multiple ligament injuries. Methods We retrospectively reviewed the data of patients with Schenck II–IV knee dislocations and multiple ligament injuries treated in our hospital during 2019–2022. …”
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The influence of type 2 diabetes mellitus on clinical manifestations of osteoarthritis by E. A. Taskina, L. I. Alekseeva, N. G. Kashevarova, E. A. Strebkova, E. P. Sharapova, N. M. Savushkina, K. M. Mikhailov, T. A. Raskina, I. B. Vinogradova, E. N. Otteva, E. V. Zonova, O. N. Anoshenkova, A. M. Lila

“…Objective: to investigate in a multicenter study relationship between type 2 diabetes mellitus (DM) and clinical manifestations of osteoarthritis (OA). Material and methods. The study involved 767 patients aged 40–75 years with a confirmed diagnosis of stage I–III knee OA who had signed an informed consent form. …”
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The dose-dependent efficacy of esketamine in spinal surgery with intraoperative neuroelectrophysiological monitoring: a randomized controlled trial by Chunyan Lin, Chunyan Lin, Jianlin Wang, Long Zhang, Long Zhang, Liyong Yuan, Guanyi Liu, Guanyi Liu, Miao Zhu, Liangguang Zhang

“…PurposeThis study aims to validate the efficacy and safety of combining different doses of esketamine with propofol, remifentanil, and dexmedetomidine in spinal surgery under intra-operative neuroelectrophysiological monitoring (IONM).MethodsAll enrolled patients underwent a total intravenous anesthesia (TIVA) maintenance regimen, which included propofol, remifentanil, and dexmedetomidine. …”
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Endoscopic Flexor Hallucis Longus Transfer With Interference Screw and Additional Tension Slide Cortical Button for Chronic Achilles Tendon Rupture by Ayla Claire Newton MBBS(Hons), MA(Cantab), MRCS, Samuel Franklin MBBCh(Hons), MRCS, Thomas Lorchan Lewis MBChB(Hons), BSc(Hons), MFSTEd, FRCS(Tr&Orth), Sanjana Mehrotra, Siddhartha Murhekar MBBS, MRCS, Vikramman Vignaraja MBBS, BSc(Hons), Robbie Ray MBChB, ChM(T&O), FRCSed(Tr&Orth), FEBOT

“…The aim of this study was to explore patient-reported functional outcomes following this modification to this operation. Methods We reviewed the imaging, history, patient-related outcome measures (PROMs), and complications of 17 patients who underwent endoscopic FHL tendon transfer for chronic ATR using the modified FHL reconstruction technique. …”
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What is the role of family meals and social eating behaviour in relation to experiential avoidance in adolescents among Spanish adolescents: the EHDLA study by Estela Jimenez-Lopez, Arthur Eumann Mesas, José Francisco López-Gil, Rodrigo Yáñez-Sepúlveda, Jorge Olivares-Arancibia, José Adrián Montenegro-Espinosa, Héctor Gutiérrez-Espinoza, Daniel Duclos-Bastías

“…Purpose The aim of the present study was to analyse the associations of family meals and social eating behaviour (SEB) with experiential avoidance (EA) in adolescents from Spain.Methods This cross-sectional study involved 617 adolescents (aged 12–17 years, 56.7% females) from the Eating Habits and Daily Life Activities study from Valle de Ricote (Region of Murcia, Spain). …”
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Assessing ChatGPT’s Capability as a New Age Standardized Patient: Qualitative Study by Joseph Cross, Tarron Kayalackakom, Raymond E Robinson, Andrea Vaughans, Roopa Sebastian, Ricardo Hood, Courtney Lewis, Sumanth Devaraju, Prasanna Honnavar, Sheetal Naik, Jillwin Joseph, Nikhilesh Anand, Abdalla Mohammed, Asjah Johnson, Eliran Cohen, Teniola Adeniji, Aisling Nnenna Nnaji, Julia Elizabeth George

“…ObjectivesThis study aims to assess medical students’ perceptions and experiences of using ChatGPT as an SP and to evaluate ChatGPT’s effectiveness in performing as a virtual SP in a medical school setting. MethodsThis qualitative study, approved by the American University of Antigua Institutional Review Board, involved 9 students (5 females and 4 males, aged 22‐48 years) from the American University of Antigua College of Medicine. …”
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A pilot study investigating the effectiveness, appreciation, and feasibility of a cognitive stimulation program in dementia patients: online versus face-to-face by Simona Cintoli, Giulia Spadoni, Valeria Giuliani, Valentina Nicoletti, Eleonora del Prete, Daniela Frosini, Roberto Ceravolo, Roberto Ceravolo, Gloria Tognoni

“…The study aimed to evaluate whether a cognitive stimulation protocol could be adapted for remote use, particularly for patients facing logistical challenges.MethodsThe study involved 19 dementia patients (Clinical Dementia Rating = 1 or 2), with 12 undergoing in-person treatment and seven participating remotely. …”
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Predictive Factors and Nomogram for 30-Day Mortality in Heatstroke Patients: A Retrospective Cohort Study by Anxin Li, Yuchen Zhang, Xiaoshi Zhang, Zixiao Duan, Yan Chen, Xiaoyan Jiang, Wuquan Deng

“…In this study we aimed to identify early risk factors that impacted the 30-day mortality of HS patients and establish a predictive model to assist clinicians in identifying the risk of death. Methods: We conducted a retrospective cohort study, analyzing the clinical data of 203 HS patients between May 2016–September 2024. …”
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SPING Block Analgesia in Non-Operative Management of Proximal Femur Fractures in Older Adults Living with Frailty: A Retrospective Cohort Study by Miriam W. A. van der Velden, Thamar Kroes, Nick J. G. Visschers, Frank P. J. F. de Loos, Pleun Janssens, Bart Spaetgens, Miriam C. Faes, Marieke H. J. van den Beuken-van Everdingen, Arnela Suman

“…This study evaluated the patient, safety, and process outcomes of SPING block in this population. <b>Methods</b>: A retrospective cohort study was conducted in a suburban teaching hospital from March 2021 to June 2024, which included sixty-eight older adults living with frailty that suffered from a PFF and received SPING block. …”
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Knowledge, Attitudes, and Practices of Parents Regarding Ophthalmological Screening of Preschool-Aged Children in Jazan, Saudi Arabia by Mohamed Salih Mahfouz, Samy Shaban Mahmoud, Saleha Qaseem Haroobi, Latifah Mohammed Bahkali, Shahad Ibrahim Numan, Areen Mohsen Taheri, Ohoud Ali Hakami, Orjuwan Adel Zunquti, Sarah Mohammed Khered

“…This study assesses parents’ knowledge, attitudes, and practices regarding the early ophthalmological screening of preschool-aged children in Jazan, KSA. Methods: An observational cross-sectional study was conducted among 522 parents of preschool-aged children in the Jazan region. …”
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Urinary metal levels and their association with Parkinson’s disease risk: insights from NHANES 2013–2020 by Jia-jie Lv, Jia-jie Lv, Xin-yu Li, Xin-yu Li, Cheng-hao Yang, Cheng-hao Yang

“…This research focused on investigating the relationship between urinary metal levels and the likelihood of developing PD.MethodsUsing data from the National Health and Nutrition Examination Survey (NHANES), urinary levels of nine metals—barium (Ba), cadmium (Cd), cobalt (Co), cesium (Cs), molybdenum (Mo), lead (Pb), antimony (Sb), thallium (Tl), and uranium (Tu)—were measured in a cohort of 3,148 US adults. …”
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Accuracy of screening tests for cervical precancer in women living with HIV in low-resource settings: a paired prospective study in Lusaka, Zambia by Nicola Low, Partha Basu, Andreas Limacher, Katayoun Taghavi, Misinzo Moono, Mulindi Mwanahamuntu, Herbert Kapesa, Albert Manasyan, Julia Bohlius, Marie Roumet, Thamsanqa Madliwa, Anne Rutjes

“…We assessed the accuracy of screening tests that can be used in low-resource settings and give results at the same visit.Methods and analysis We conducted a paired, prospective study among consecutive eligible WLHIV, aged 18–65 years, receiving cervical cancer screening at one hospital in Lusaka, Zambia. …”
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A CT-based subregional radiomics nomogram for predicting local recurrence-free survival in esophageal squamous cell cancer patients treated by definitive chemoradiotherapy: a multi... by Jie Gong, Jianchao Lu, Wencheng Zhang, Wei Huang, Jie Li, Zhi Yang, Fan Meng, Hongfei Sun, Lina Zhao

“…Abstract Background To develop and validate an online individualized model for predicting local recurrence-free survival (LRFS) in esophageal squamous cell carcinoma (ESCC) treated by definitive chemoradiotherapy (dCRT). Methods ESCC patients from three hospitals were randomly stratified into the training set (715) and the internal testing set (179), and patients from the other hospital as the external testing set (120). …”
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Collecting patient-reported outcomes via the COTIDIANA smartphone app: a prospective validity study by Daniel Aletaha, Tanja A Stamm, Paul Studenic, Helga Radner, Nadja Kartschmit, Elsa Frãzao-Mateus, Nasim Nakhost Lotfi, Francisco Nunes, Pedro Matias, Ricardo Graca

“…We aimed to assess the reliability and comparability of frequent remote monitoring by using ePROMs via a smartphone.Methods Patients (≥18 years) with Sjögren’s disease (SjD), osteoarthritis (OA) and psoriatic arthritis (PsA) were recruited from our outpatient clinic and asked to complete seven short daily as well as weekly questions (visual analogue scale) on global disease activity (PGA), pain, anxiety and depression, fatigue and sleep) for 14 days. …”
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Exogenous Application of 1-Aminocyclopropane-1-carboxylic Acid as a New Strategy to Trigger the Color Development of Table Grapes Grown in Subtropics by Aline Cristina de Aguiar, Fábio Yamashita, Renata Koyama, Bruna Evelise Bosso Caetano, Carlos Akira Komoli Utiamada, Sergio Ruffo Roberto

“…Treatments were exogenously applied at <i>véraison</i>, and for each cultivar, two trials were conducted independently, including two methods of application: to the entire canopy of the vines or only to the bunches, totaling four independent trials. …”
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Non-invasive neuromodulation for alleviating dyspnoea: protocol for a feasibility sham-controlled randomised trial by Guillaume Léonard, Christian Iorio-Morin, Simon Couillard, Joël St-Pierre, Samuel Mailhot-Larouche, Geneviève Garand, Félix-Antoine Vézina

“…We speculate that non-invasive transcutaneous vagus nerve stimulation (tVNS) and trigeminal transcutaneous electric nerve stimulation (TENS) could improve dyspnoea management by targeting relevant neural circuits.Methods and analysis We will conduct a feasibility cross-over trial in people with severe COPD and significant exertional dyspnoea referred for pulmonary rehabilitation. …”
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