Association between psychosocial factors at work and health outcomes after retirement: a protocol for a systematic review and meta-analysis by Hisashi Eguchi, Akizumi Tsutsumi, Akiomi Inoue, Yuka Kobayashi, Norito Kawakami, Kotaro Imamura, Asuka Sakuraya, Natsu Sasaki, Yumi Asai, Hideaki Arima, Emiko Ando, Reiko Inoue, Mai Iwanaga, Yasumasa Otsuka, Kanami Tsuno, Ayako Hino, Kazuhiro Watanabe, Akihito Shimazu

“…The objective of this systematic review and meta-analysis is to examine the association between psychosocial factors at work and health outcomes after retirement, based on a synthesis of well-designed prospective studies.Methods and analysis The participants, exposures, comparisons and outcomes of the studies in this systematic review and meta-analysis are defined as follows: (P) people who have retired from their job, (E) presence of adverse psychosocial factors at work before retirement, (C) absence of adverse psychosocial factors at work before retirement and (O) any physical and mental health outcomes after retirement. …”
Get full text

External application of Traditional Chinese medicine in the treatment of acute gouty arthritis (中药外敷治疗急性痛风性关节炎临床效果及护理) by LI Juan (李娟), ZHENG Xiaoya (郑小雅), ZHANG Haiying (张海英), DU Danying (杜丹颖), HAN Shuhua (韩淑花), LI Yan (李雁)

“…Objective To observe the clinical effect of external application of Traditional Chinese Medicine(TCM) in the treatment of acute gouty arthritis. Methods Totally 61 patients with acute gouty arthritis who met the inclusion criteria were included as research subjects. …”
Get full text

CHI study: protocol for an observational cohort study on ageing and mental health in community-dwelling older adults by Lei Feng, Lieng Hsi Ling, Qiushi Feng, Rachael Zhi Yi Lee, Junhong Yu, Iris Rawtaer, Patrick Finbarr Allen, Zhiming Bao, Jeong Kyu Lee, Chin Tat Lim, Leng Leng Thang, Thet Naing, D Y Wang, Kai Zhen Yap, EH Kua, Rathi Mahendran

“…The Community Health and Intergenerational study aims to holistically examine ageing in place by investigating the resilience and vulnerability factors of the ageing process in the biological, psychological and social domains within the environment.Methods and analysis Using a cohort multiple randomised controlled trial design, comprehensive health profiles of community-dwelling older adults will be collected. …”
Get full text

Distinctive clinical features of early and late-onset Ménière’s disease by Jianwei Lin, Heng Xiao, Heng Xiao, Heng Xiao, Chenxin Lin, Gengliang Huang, Xiaojing Guo, Huimin Cai, Huimin Cai, Huimin Cai, Shengnan Ye, Shengnan Ye, Shengnan Ye

“…PurposeTo compare the clinical characteristics of patients with early and late-onset Ménière’s disease (MD) and to investigate the impact of psychological factors between the two groups.MethodsThe patients were divided into two groups based on their age of onset: early-onset (<45 years old) and late-onset (>55 years old). …”
Get full text

Associations of long-term joint exposure to multiple ambient air pollutants with the incidence of age-related eye diseases by Yingan Li, Yuzhou Zhang, Ka Wai Kam, Poemen Chan, Dong Liu, Ebenezer Zaabaar, Xiu Juan Zhang, Mary Ho, Mandy PH Ng, Patrick Ip, Alvin Young, Chi Pui Pang, Clement C. Tham, Mei Po Kwan, Li Jia Chen, Jason C. Yam

Get full text

Comparative analysis of mini-open trans-thoracic transpleural and posterior approaches in thoracic disc herniation surgery: A 10-year retrospective review by Ali Baram, Giorgio Cracchiolo, Marco Riva, Gabriele Capo, Leonardo Anselmi, Carlo Brembilla, Stefania Radice, Maria Pia Tropeano, Carla Anania, Emanuela Morenghi, Maurizio Fornari, Federico Pessina

“…Research question: What are the clinical, surgical, and radiological outcomes of anterior and posterior surgical approaches for TDHs over a 10-year period? Material and methods: A retrospective analysis of 54 patients who underwent surgery for TDHs (2013–2022) was performed. …”
Get full text

Anatomic characteristics of the lacrimal sac and adjacent bony structures–a computed tomographic-dacryocystography research by Xin-Han Cui, Yan-Wen Fang, Li-Min Zhang, Ji-Ni Qiu, Chao-Ran Zhang, Yan Wang

Get full text

Bile Acid Metabolism Changes in Patients with a CRB1-Associated Inherited Retinal Degeneration by Lude Moekotte, MD, PhD, Joke H. de Boer, MD, PhD, Sanne Hiddingh, MSc, Bram Gerritsen, PhD, Jutta Lintelmann, PhD, Alexander Cecil, PhD, L. Ingeborgh van den Born, MD, PhD, Xuan-Thanh-An Nguyen, MD, PhD, Camiel J.F. Boon, MD, PhD, Maria M. van Genderen, MD, PhD, Jonas J.W. Kuiper, PhD

Get full text

Impact of religious fasting on ocular dryness: objective and subjective assessment by Amal F. Alomari, Sara Issa, Asma Musleh, Mohammad Abusamak, Mohammad Abusamak, Omar Bdair, Omar Bdair, Saif Aldeen AlRyalat, Saif Aldeen AlRyalat, Alanoud Al-Wakfi, Mohammed Jaber, Ahmad Alloubani, Haitham Sahawneh, Haitham Sahawneh, Muhannd El-Faouri, Ayman Abdul Aziz, Muawyah Al Bdour

Get full text

Combining patient-reported outcome measures to screen for active disease in rheumatoid arthritis and psoriatic arthritis by Annette H M van der Helm-van Mil, Pascal H P de Jong, Paco M J Welsing, Ilja Tchetverikov, Jolanda J Luime, Marijn Vis, Marc R Kok, Paul Baudoin, Lindy-Anne Korswagen, Selinde V J Snoeck Henkemans, Agnes E M Looijen, Gonul Hazal Koc

“…Objectives To investigate whether a combination of general health (Visual Analogue Scale (VAS)), Health Assessment Questionnaire-Disability Index (HAQ-DI), pain (VAS/Numerical Rating Scale (NRS)), quality of life (EQ-5D), fatigue (VAS/NRS) and presenteeism (0%–100% productivity loss) could aid as a screening tool to detect active disease in patients with rheumatoid arthritis (RA) and psoriatic arthritis (PsA).Methods RA patients from the tREACH trial and TARA trial (n=683) and PsA patients from the DEPAR cohort (n=525) were included. …”
Get full text

Increased Risk of Central Serous Chorioretinopathy among Patients with Nonorganic Sleep Disturbance by Peng-Tai Tien, Chien-Yu Lai, Chun-Ju Lin, Wen-Lu Chen, Po-Kang Lin, Chih-Hsin Muo, Yi-Yu Tsai, Lei Wan, Wen-Chao Ho, Hui-Ju Lin

“…Patients with central serous chorioretinopathy (CSC) typically present with acute visual impairment and metamorphopsia. The disease previously has been associated with psychological stress. …”
Get full text

Systemizing and Transforming Preterm Oral Feeding Through Innovative Algorithms by Rena Rosenthal, Jean Chow, Erin Sundseth Ross, Rudaina Banihani, Natalie Antonacci, Karli Gavendo, Elizabeth Asztalos

“…These feelings of uncertainty are exacerbated by the non-linear progression of oral feeding development and the absence of a systematized approach to initiate and advance feedings. <b>Methods:</b> In this 48-bed tertiary perinatal centre, staff surveys and a needs assessment showed dissatisfaction and increasing stress and anxiety due to the inconsistencies in initiating and advancing oral feeds. …”
Get full text

An Effective and Safe Laser Treatment Strategy of Fractional Carbon Dioxide Laser for Chinese Populations with Periorbital Wrinkles: A Randomized Split-Face Trial by Xianglei Wu, Qingqing Cen, Jian Jin, Wei Gao, Ying Shang, Linting Huang, Xiaoxi Lin

“…We aimed to explore the optimum energy and coverage parameters of CO2 AFL for treating static periorbital wrinkles in a Chinese population and to minimize PIH incidence. Methods In total, 30 patients with static periorbital wrinkles were recruited. …”
Get full text

Development and temporal external validation of a novel nomogram for predicting one-year mortality in the older adult with hip fracture by Yangfan Gong, Kai Zhang, Wei Chen, Qiqi Yang, Mingyue Shi, Zhao Dong, Zhuohao Yin, Yuyu Zhang, Wei Ge

“…ObjectiveThe aim of this study was to develop a novel nomogram for predicting one-year mortality in the older adult patients with hip fracture and to further evaluate its effectiveness.MethodsThis retrospective cohort research analyzed the clinical data of 1,263 older adult patients with hip fractures who underwent surgery at the First Affiliated Hospital of Air Force Military Medical University from January 2014 to December 2022. …”
Get full text

Epigenetic modifications are associated with mRNA and cytokine expression changes in chronic rhinosinusitis: a multiomics study from the United States by Devyani Lal, Tripti Brar, Chantal McCabe, Erik Jessen, Nitish Kumar, Pedro Lança Gomes, Michael J. Marino, Amar Miglani, Hirohito Kita

“…We therefore performed a multi-omics study integrating epigenetic (DNA methylation), transcriptomic (mRNA), and proteomic (cytokine) data of CRS sinonasal tissue to visualize interactions amongst these modalities to study our hypothesis.MethodsSinonasal tissue was collected from 14 prospectively enrolled CRS and control subjects. …”
Get full text

Aspartate aminotransferase-to-platelet ratio index as a novel predictor of early mortality in heat stroke patients: a multi-centre retrospective study by Min Wang, Yun Li, Yuan Cao, Meng-Meng Yang, Fu-Jing Liu, Jie Jiao, Sheng-Yuan Wang, Bin Song, Lu Wang, Yi-Qi Wu, Hong-Jun Kang

“…Restricted cubic splines (RCS) were utilized to visualize the relationship between APRI and 28-day mortality risk. …”
Get full text

Effect of Traditional Chinese Medicine ointment rubbing therapy in the treatment of primary dysmenorrheal (中药膏摩治疗原发性痛经疗效观察) by CAO Lei (曹蕾), ZHANG Lijun (张丽君), KONG Xiaochun (孔晓春), CHEN Hong (陈宏)

“…Objective To investigate the effect of rubbing therapy with Traditional Chinese Medicine (TCM) ointment in the treatment of primary dysmenorrheal. Methods Totally 82 patients with primary dysmenorrheal were randomly divided into the treatment group and control group, with 41 cases in each group. …”
Get full text

AlphaMissense Predictions and ClinVar Annotations: A Deep Learning Approach to Uveal Melanoma by David J. Taylor Gonzalez, MD, Mak B. Djulbegovic, MD, MSc, Meghan Sharma, MD, MPH, Michael Antonietti, BS, Colin K. Kim, BS, Vladimir N. Uversky, PhD, DSc, Carol L. Karp, MD, Carol L. Shields, MD, Matthew W. Wilson, MD

“…Subjects: Genetic data from patients diagnosed with UM were analyzed, explicitly focusing on missense mutations sourced from the Catalogue of Somatic Mutations in Cancer (COSMIC) database. Methods: We identified missense mutations frequently observed in UM using the COSMIC database, assessed their potential pathogenicity using AlphaMissense, and visualized mutations using AlphaFold. …”
Get full text

Pediatric endoscopic retrograde pancreatography expertise in chronic pancreatitis: a single-center analysis by Hongxi Guo, Juan Luo, Hu Yang, Jun Yang, Hongqiang Bian, Xufei Duan, Xin Wang

“…However, data on endoscopic treatment of CP in children are still limited.MethodsDemographics, etiology, surgical indications, diagnosis, treatment details, associated complications, and follow-up information were retrospectively studied in consecutive patients (&lt;18 years old) who underwent ERP for CP between January 2020 and October 2024.ResultsA total of 17 children (7 male, 10 female) with a mean age of 10.0 ± 2.7 years were included in the study. …”
Get full text

Outcomes of Bilateral Scandinavian Total Ankle Replacement: A Detailed Analysis of Implant Survivability and Patient-Reported Outcomes by Alexandra Hunter Aitchison BS, Albert T. Anastasio MD, Kevin A. Wu BS, Emily Poehlein MB, Cynthia Green PhD, Samuel B. Adams MD, James K. DeOrio MD, Mark E. Easley MD, James A. Nunley MD

“…This study aimed to evaluate the survivability and patient-reported outcomes of simultaneous bilateral STAR, focusing on implant survival rates and improvements in quality of life, function, and pain relief. Methods: A retrospective cohort study was conducted on all patients managed with primary TAR performed simultaneously with bilateral STAR prostheses at our institution from July 1998 to February 2008. …”
Get full text