Applications of Machine Learning-Driven Molecular Models for Advancing Ophthalmic Precision Medicine by Rahul Kumar, Joshua Ong, Ethan Waisberg, Ryung Lee, Tuan Nguyen, Phani Paladugu, Maria Chiara Rivolta, Chirag Gowda, John Vincent Janin, Jeremy Saintyl, Dylan Amiri, Ansh Gosain, Ram Jagadeesan

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Clinicopathologic features of 89 patients with lacrimal gland prolapse by Yu-Yao Qu, Le Dong, Ya-Guang Hu, Ning Gao, Jing-Ming Li, Qiao-Chu Cheng, Shan Gao, Ting Wei, Jian-Min Ma, Wan-Hu Zhang

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Application of family-centered care in cardiac surgery: a scoping review by Duo Zhang, Haoyang Zheng, Yong Gan, Xichen Chai, Ying Zeng, Xiaoyan Yu, Wencan Cheng, Ya Zhao, Zelin Chen, Yanrong Zhou

“…Objectives To identify the current state of the application of FCC in the families of cardiac surgery. Methods This study followed Arksey and O’Malley’s methodology and the PRISMA extension for Scoping Reviews. …”
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Strategies for Maintaining Balance in Patients with Parkinson’s Disease by A. E. Slotina, Ekaterina S. Ikonnikova, Georgii A. Kotsoev, Alena S. Egunova, Uliana V. Panina, Ekaterina Yu. Fedotova, Elena V. Gnedovskaya, Natalia A. Suponeva

“…The study was aimed at investigating balance maintenance strategies during PD “on” and “off” periods using classical and integral stabilometric parameters. Materials and methods. The study included 27 PD patients with the median of 61 years. …”
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Incision capsular bag herniation during subluxated lens surgery: mechanisms, management, and prevention by Shuang Ni, Shuang Ni, Danni Lyu, Danni Lyu, Jianxia Fang, Jianxia Fang, Wen Xu, Wen Xu

“…PurposeTo investigate the mechanism, intraoperative characteristics, management, and prevention of incision capsular bag herniation (ICBH), a previously unreported complication during cataract surgery in eyes with lens subluxation.MethodsA retrospective observational case series was conducted on five male patients who developed ICBH during phacoemulsification with intraocular lens (IOL) implantation between January 2019 and December 2024. …”
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Phacoemulsification and Visco-synechiolysis With or Without Trabeculectomy Following Initial Management of Acute Primary Angle Closure: A Comparative Study by Mahdi Sharifzadeh Kermani, Mina Haj-mohammad Karimi, Ali Sharifi, Mahla Shadravan, Arash Daneshtalab, Amin Zand

“… Purpose: To assess the effects of phacoemulsification, visco-synechiolysis, and trabeculectomy on eyes with a recent history of acute primary angle closure (APAC). Methods: In this prospective nonrandomized study, we enrolled patients with cataracts, peripheral anterior synechiae (PAS), and a history of APAC attack managed with medications and laser peripheral iridotomy (LPI) within the past six weeks. …”
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Impact of filgotinib on pain control in the phase 3 FINCH studies by Bruno Fautrel, Peter Nash, Arthur Kavanaugh, Peter C Taylor, René Westhovens, Rieke Alten, Janet Pope, Dick de Vries, Chris Watson, Georg Pongratz, Pieter-Jan Stiers, Ken Hasegawa, Shangbang Rao

“…Objective This post hoc analysis of the FINCH 1–3 (NCT02889796, NCT02873936 and NCT02886728) studies assessed specific effects of filgotinib on pain control and their relationship with other aspects of efficacy in patients with rheumatoid arthritis (RA).Methods Assessments included: residual pain responses of ≤10 and ≤20 mm on a 100 mm visual analogue scale (VAS); the proportion of patients who achieved VAS pain responses in addition to remission or low disease activity by Disease Activity Score-28 with C-reactive protein (DAS28-CRP) or Clinical Disease Activity Index (CDAI) criteria.Results Across studies, filgotinib reduced pain from week 2, with responses sustained throughout the studies. …”
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The MinDag app for symptom monitoring and feedback to patients and clinicians during the initial treatment of bipolar disorder – a feasibility study by Margrethe Collier Høegh, Stine Holmstul Glastad, Siv Hege Lyngstad, Magnus Johan Engen, Sofie Ragnhild Aminoff, Ingrid Melle, Thomas Bjella, Trine Vik Lagerberg

“…This study aims to evaluate the practical use and clinical implications of integrating MinDag in the early treatment of bipolar disorder from the perspectives of both patients and clinicians. Methods The MinDag app includes six content modules covering mood, sleep, functioning/activities, substance use, emotional reactivity, and psychotic symptoms. …”
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AlzheimerViT: harnessing lightweight vision transformer architecture for proactive Alzheimer’s screening by C. Kishor Kumar Reddy, Hafsa Ihteshamuddin Ahmed, Muhammad Mohzary, Muhammad Mohzary, T. Monika Singh, Mohammed Shuaib, Shadab Alam, Hani Mohammed Alnami, Hani Mohammed Alnami

“…Deep learning techniques, mainly when applied to MRI data, have proven helpful in the early detection of Alzheimer’s Disease.MethodsIn the proposed study, a lightweight, self-attention-based vision transformer (ViT) is employed to predict Alzheimer’s disease using MRI images from the OASIS-3 dataset. …”
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Uniportal endoscopic decompression and debridement for infectious diseases of spine with neurological deficits: a retrospective study in China by Hui Lv, Jianhong Zhou, Yuan Guo, Sheng Liao, Hui Chen, Fei Luo, Jianzhong Xu, Zhongrong Zhang, Zehua Zhang

“…However, the efficacy of UEDD in this complex patient population is not well-characterized. Methods This retrospective study analyzed 32 consecutive IDS patients who underwent UEDD surgery. …”
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Impact of Lidocaine Concentration on Analgesic Efficacy and Adverse Events in Dermatologic Infiltrative Anesthesia by Van Thanh Le Thai, Tri Thong Nguyen, Quoc Hung Ta, Anh Tuan Ngo, Thanh Yen Thai Thanh Yen, Phuong Thao Nguyen, Vi Anh Le, Ngoc Khanh Nam Tran, Hanh Vy Tran

“…Objective: We aimed to investigate the correlation between three different concentrations of lidocaine (2% lidocaine with 1:100,000 epinephrine diluted at ratios of 1:2, 1:4, and 1:6) used in infiltrative anesthesia and their analgesic efficacy and adverse effects in dermatologic procedures. Methods: This study employed a randomized design, with 240 patients assigned to receive varying concentrations of lidocaine with epinephrine (2% lidocaine  with 1:100,000 epinephrine diluted at ratios of 1:2, 1:4, or 1:6) during 7 common dermatologic procedures: punch biopsy, excisional biopsy, CO2 laser biopsy, surgical excision, CO2 laser excision, fractional CO2 laser treatment, and filler injection. …”
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Preserflo™ microshunt for the treatment of refractory childhood glaucoma: A case series study by Yuri Tanaka, Shiho Kasahara, Ryo Tomita, Norie Nonobe, Kazuhide Kawase, Kenya Yuki

“…Purpose: We report the outcomes of five patients with pediatric glaucoma, who were treated with Preserflo™ microshunt surgery. Methods: This prospective study included five consecutive patients who underwent Preserflo™ microshunt surgery at the Nagoya University Hospital. …”
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Efficacy of brief intervention for drug misuse in primary care facilities: systematic review and meta-analysis protocol by Toshi A Furukawa, Yan Luo, Norio Watanabe, Ethan Sahker, Masatsugu Sakata, Rie Toyomoto, Chiyoung Hwang, Kazufumi Yoshida

“…The aim of this systematic review and meta-analysis is to determine the efficacy of BI for drug misuse in primary care settings.Methods and analysis We will include all randomised controlled trials comparing primary care-delivered BI for drug misuse with no intervention or minimal screening/assessment and usual care. …”
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Minilaparoscopic Versus Conventional Laparoscopic Hysterectomy: Insights from a Single-Center Retrospective Cohort Study with Legal Considerations by Valentina Billone, Giuseppe Gullo, Eleonora Conti, Silvia Ganduscio, Sofia Burgio, Giovanni Baglio, Gaspare Cucinella, Lina De Paola, Susanna Marinelli

“…<i>Background and Objectives</i>: We compared mini-laparoscopic and laparoscopic hysterectomy in terms of surgery duration, postoperative pain, conversion rate, blood loss, postoperative complications (Clavien-Dindo classification), and the length of hospital stay. <i>Materials and Methods</i>: Patients were recruited between 1 January 2017 and 1 January 2024, at the Department of Gynecology, “Villa Sofia-Cervello” Hospital. …”
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Enhancing Blood–Brain Barrier Integrity in Patients With Acute Ischemic Stroke Via Normobaric Hyperoxia by Weili Li, Wenbo Hu, Shuhua Yuan, Jiahao Chen, Qi Wang, Jiayue Ding, Zhiying Chen, Zhifeng Qi, Ju Han

“…Serum markers were assessed using ELISA, and intracranial contrast extravasation was visualized using dual‐energy computed tomography scan. …”
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Evaluation of enhanced pain management programs for patients undergoing surgery for severe knee osteoarthritis: a retrospective study by Peng Liu, Jiabing Li, Weimin Liang, Xiao Yang, Jiang Hu, Chongxin Huang, Ji Zhou

“…This study aimed to evaluate the clinical outcomes of different postoperative analgesic protocols to inform optimized perioperative pain strategies.Methods A retrospective analysis was conducted on 714 patients with knee OA who underwent total knee arthroplasty (TKA, n = 551), unicompartmental knee arthroplasty (UKA, n = 92), or high tibial osteotomy (HTO, n = 71). …”
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Femtosecond laser-assisted in situ keratomileusis for the correction of residual ametropia after penetrating keratoplasty: 1-year follow-up by Dario Pasquale Mucciolo, Giancarlo Albani, Luca Terracciano, Marco Branchetti, Laura Luchetti, Vittoria Murro, Gianni Virgili, Gianni Virgili, Fabrizio Giansanti

“…We evaluated the 1-yr follow up of laser-assisted in situ keratomileusis using femtosecond laser (LASIK) for the correction of residual ametropia after penetrating keratoplasty (PK).MethodsTen eyes of 10 patients were treated using corneal Femto-LASIK (F-LASIK) (WaveLight® Refractive Suite, Alcon) to correct refractive errors after PK at Careggi Teaching Hospital (Florence, Italy). …”
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Characterisation of HER2‐Driven Morphometric Signature in Breast Cancer and Prediction of Risk of Recurrence by N. M. Atallah, S. Makhlouf, M. Nabil, A. Ibrahim, M. S. Toss, N. P. Mongan, E. Rakha

“…In this study, we hypothesised that the degree of HER2 oncogenic activity, and hence response to anti‐HER2 therapy is translated into a morphological signature that can be of prognostic/predictive value. Methods We developed a HER2‐driven signature based on a set of morphometric features identified through digital image analysis and visual assessment in a sizable cohort of BC patients. …”
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Analysis of structural and vascular changes of the optic nerve head and macula in different stages of primary open angle glaucoma by Petrović Maja, Resan Mirko, Stanković-Babić Gordana, Šarenac-Vulović Tatjana, Radenković Marija, Veselinović Aleksandar, Trenkić Marija, Cvetanović Marija

“…Patient characteristics were similar except for decreased visual acuity, thinner corneas, higher intraocular pressure and higher cup/disc ratio in POAG patients. …”
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Two-year follow-up of unilateral biportal endoscopy assisted extraforaminal lumbar interbody fusion: how to perform indirect decompression and fusion under endoscopy: a retrospecti... by Takaki Yoshimizu, Sanshiro Saito, Teruaki Miyake, Tetsutaro Mizuno, Ushio Nosaka, Keisuke Ishii, Mizuki Watanabe, Kanji Sasaki

“…However, no studies have compared the efficacy of ELIF performed under unilateral biportal endoscopy with that of OLIF. Methods Forty-nine adults who underwent single-level L4/5 interbody fusion for degenerative spondylolisthesis were divided into BE-ELIF (n=27) and OLIF (n=22) groups based on the surgical approach used. …”
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