RECOMMENDED TACTICS FOR THE EVALUATION OF POTENTIALLY MALIGNANT DISORDERS IN THE ORAL CAVITY by S.V. Kolomiiets, K.O. Udaltsova, V.I. Shynkevych

“…A pattern of action in such situations is referring patients directly to an oncologist, who will conduct a biopsy, histological examination and treat the cancer. Consequently, the attention of Ukrainian dentists is focused on precancerous lesions, but less attention is paid actually to the cancer. …”
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Evaluation of the Effectiveness of Pulsed Ultraviolet Devices in Medical Premises of the Emergency Department of a Hospital Under Conditions of Intensive Patient Flow by B. L. Kurilin, N. E. Drozdova, A. Yu. Perminov, E. V. Kislukhina, Ya. V. Kulikova, N. S. Fomenko, A. V. Shapoval, V. I. Drozdova, A. R. Samarin

“…Preventive disinfection of work surfaces was carried out after each patient by wiping with the use of approved products.The experimental premises were treated according to a single standard algorithm, including treatment with the Installation.To collect microbiological swabs, sampling points were defined in the studied premises (4 in each). …”
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The role of intracellular signaling in the stripe formation in engineered Escherichia coli populations. by Xiaoru Xue, Chuan Xue, Min Tang

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Atypical structural tendencies among low-complexity domains in the Protein Data Bank proteome. by Sean M Cascarina, Mikaela R Elder, Eric D Ross

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Early cessation of pressure garment therapy results in scar contraction and thickening. by Danielle M DeBruler, Jacob C Zbinden, Molly E Baumann, Britani N Blackstone, Megan M Malara, J Kevin Bailey, Dorothy M Supp, Heather M Powell

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Oxaliplatin-induced changes in microbiota, TLR4+ cells and enhanced HMGB1 expression in the murine colon. by Vanesa Stojanovska, Rachel M McQuade, Sarah Fraser, Monica Prakash, Shakuntla Gondalia, Rhian Stavely, Enzo Palombo, Vasso Apostolopoulos, Samy Sakkal, Kulmira Nurgali

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Proteomic response of hybrid wild rice to cold stress at the seedling stage. by Jinzi Wang, Jun Wang, Xin Wang, Rongbai Li, Baoshan Chen

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Changes in parasite traits, rather than intensity, affect the dynamics of infection under external perturbation. by Suma Ghosh, Matthew J Ferrari, Ashutosh K Pathak, Isabella M Cattadori

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One round of azithromycin MDA adequate to interrupt transmission in districts with prevalence of trachomatous inflammation-follicular of 5.0-9.9%: Evidence from Malawi. by Khumbo Kalua, Alvin Chisambi, David Chinyanya, Michael Masika, Ana Bakhtiari, Rebecca Willis, Paul M Emerson, Anthony W Solomon, Robin L Bailey

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The effect of pulsed electromagnetic field exposure on osteoinduction of human mesenchymal stem cells cultured on nano-TiO2 surfaces. by Nora Bloise, Loredana Petecchia, Gabriele Ceccarelli, Lorenzo Fassina, Cesare Usai, Federico Bertoglio, Martina Balli, Massimo Vassalli, Maria Gabriella Cusella De Angelis, Paola Gavazzo, Marcello Imbriani, Livia Visai

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Notch signaling regulates the responses of lipopolysaccharide-stimulated macrophages in the presence of immune complexes. by Wipawee Wongchana, Pornrat Kongkavitoon, Pattarin Tangtanatakul, Chutamath Sittplangkoon, Patcharavadee Butta, Supatta Chawalitpong, Thitiporn Pattarakankul, Barbara A Osborne, Tanapat Palaga

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A specific expression profile of LC3B and p62 is associated with nonresponse to neoadjuvant chemotherapy in esophageal adenocarcinomas. by Olivia Adams, Félice A Janser, Bastian Dislich, Sabina Berezowska, Magali Humbert, Christian A Seiler, Dino Kroell, Julia Slotta-Huspenina, Marcus Feith, Katja Ott, Mario P Tschan, Rupert Langer

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Electronic patient-reported outcomes, fever management, and symptom prediction among patients with BRAF V600 mutant stage III–IV melanoma: The Kaiku Health platform by Peter Mohr, Paolo Ascierto, Alfredo Addeo, Maria Grazia Vitale, Paola Queirolo, Christian Blank, Jussi Ekström, Joonas Vainio, Vesa Kataja, Sibel Gunes, Mia Engström-Risku, Henriette Thole, Ailis Fagan, Frederico Calado, Ruben Marques, Judith Lijnsvelt

“…Conclusion: The Kaiku ePRO platform was well-accepted and had high compliance, with both the symptom and QoL questionnaires. The ML algorithm accurately predicted the onset and continuity of nine symptoms.…”
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Stratification system with dual human endogenous retroviruses for predicting immunotherapy efficacy in metastatic clear-cell renal cell carcinoma by Li Xu, Stephane Oudard, Catherine Sautes-Fridman, Xiaoping Su, Gabriel G. Malouf, Virginie Verkarre, Salma Kotti, Fangrong Yan, Yann-Alexandre Vano, Wolf Herve Fridman, Cheng-Ming Sun, Xiaofan Lu, Wenxuan Cheng

“…ERV expression was quantified using the ERVmap algorithm from RNA sequencing data. Our primary objective was to correlate ERV expression with progression-free survival, with overall survival and time-to-second-treatment survival as secondary endpoints. …”
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Factors associated with tuberculosis drug resistance among presumptive multidrug resistance tuberculosis patients identified in a DRTB surveillance study in western Kenya by Albert Okumu, James Orwa, Ruth Sitati, Isaiah Omondi, Ben Odhiambo, Jeremiah Ogoro, George Oballa, Benjamin Ochieng, Steve Wandiga, Collins Ouma

“…The category of previously treated patients (those who received or are currently on TB treatment) had a 70 % reduced likelihood of resistance (aOR: 0.30; 95 % CI: 0.13–0.70). …”
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Predicting clinical outcomes at hospital admission of patients with COVID-19 pneumonia using artificial intelligence: a secondary analysis of a randomized clinical trial by Caio César Souza Conceição, Camila Marinelli Martins, Mayck Medeiros Silva, Hugo Caire de Castro Faria Neto, Davide Chiumello, Davide Chiumello, Davide Chiumello, Patricia Rieken Macedo Rocco, Fernanda Ferreira Cruz, Pedro Leme Silva

“…AUCs were compared using DeLong’s algorithm.ResultsOverall, 203 patients were included in the analysis, and they were divided into two groups; clinical improvement (n = 154) and no clinical improvement (n = 49). …”
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Effect of Faricimab versus Aflibercept on Hyperreflective Foci in Patients with Diabetic Macular Edema from the YOSEMITE/RHINE Trials by Usha Chakravarthy, FRCOphth, PhD, Varun Chaudhary, MD, FRCS(C), Srinivas R. Sadda, MD, Colin S. Tan, FRCOphth, FRCSEd (Ophth), Stela Vujosevic, MD, PhD, Sascha Fauser, MD, Kara Gibson, PhD, Carl Glittenberg, MD, Nancy Holekamp, MD, FASRS, Ben Lanza, PhD, Andreas Maunz, PhD, Jeffrey R. Willis, MD, PhD, Rishi P. Singh, MD

“…Methods: A deep learning–based algorithm was used to automatically quantify HRF in spectral-domain OCT volume scans from YOSEMITE/RHINE. …”
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Network and systems biology approaches help investigate gene regulatory interactions between Salmonella disease and host in chickens: Model‐based in silico evidence combined with g... by Reza Tohidi, Hoda Javaheri Bargourooshi, Arash Javanmard

“…To start, we used free computational tools and online bioinformatics resources, including predicting gene function using a multiple association network integration algorithm (geneMania), the Kyoto Encyclopedia of Genes and Genomes, the Annotation, Visualization and Integrated Discovery (DAVID) database and the stimulator of interferon genes. …”
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Rationale and design of the HERZCHECK trial: Detection of early heart failure using telemedicine and cardiovascular magnetic resonance in structurally weak regions (NCT05122793) by Sebastian Kelle, Anna Clara Nolden, Maximilian Leo Müller, Rebecca Elisabeth Beyer, Henning Steen, Bjoern Andrew Remppis, Johannes Wieditz, Hannah Kentenich, Alex Tuit, Mina Cvetkovic, Undine Ella Witt, Florian André, Sein Schmidt, Alexander Huppertz, Dusan Simic, Dirk Müller, Arim Shukri, Matthias Issing, Andre Glardon, Katrin Christiane Reber, Ulf Landmesser, Norbert Frey, Burkert Pieske, Stephanie Stock, Volkmar Falk, Tim Friede, Gisela Thiede

“…Yet established screening algorithms for asymptomatic pre-HF, allowing for early and effective preventive interventions, are largely lacking. …”
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Tumor mutational burden and survival on immune checkpoint inhibition in >8000 patients across 24 cancer types by Vivek Subbiah, Samuel J Klempner, Neeraj Agarwal, David P Carbone, Amit Mahipal, Shilpa Gupta, David Fabrizio, Jeffrey S Ross, Gerald Li, David R Gandara, Miles C Andrews, Jonathan W Riess, Ramez N Eskander, Ryon P Graf, Geoffrey R Oxnard, Sarah Sammons, Jeremy Snider, Lilia Bouzit, Cheryl Cho-Phan, Megan Price, Julia C F Quintanilha, Richard Sheng Poe Huang

“…This study used the TMB algorithm from the FDA-approved test supporting solid tumor CDx and composite mortality variable validated against the national death index: real-world overall survival (rwOS). …”
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