Foreign bodies in the upper gastrointestinal tract in children, modern approaches to removal. A clinical case by В.А. Іванців, С.Л. Няньковський, Л.В. Ющик, О.С. Няньковська, І.М. Тумак, Т.О. Кочеркевич, О.В. Юрків, О.Н. Кочеркевич

“…The problem of providing emergency care to children who have swallowed sharp foreign bodies remains relevant and requires addressing the following issues: the timeliness of such care, the diagnostic algorithm for determining the nature of a foreign body, and the methodological aspects of the endoscopist’s procedure. …”
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Multiomics profiles of genome-wide alterations in H3K27ac in different lung lobes after acute graft-versus-host disease with MSCs treatment by Zixuan Lu, Yuming Zhou, Yuming Zhou, Chengyu Li, A. M. Abd El-Aty, A. M. Abd El-Aty, Chengxia Liu, Xiying Luan, Bin Wang, Guoyan Wang, Guoyan Wang

“…In this study, we described 55 paired transcriptomes and genome-wide H3K27ac in five lung lobes, with groups designated as follows: control, GVHD, human placenta-derived MSC (hPMSC)-treated, and PBS-treated groups. We observed that inflammatory pathways were upregulated in GVHD but downregulated in hPMSCs. …”
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Comparative Efficacy of Single Pill Combinations of Azilsartan Medoxomil/Chlorthalidone and Losartan/Hydrochlorothiazide in Patients with Hypertension and Heart Failure with Preser... by Zh. D. Kobalava, A. F. Safarova, Kh. M. Gudieva, M. A. Markova, A. E. Petrosyan

“…Average daily BP <130/ <80 mm Hg was reached by 82% of patients treated with the combination of AZM/CTD, compared with 67% treated with the combination of losartan/HCT (p<0.05). …”
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Evaluation of Peroxide Value and Free Fatty Acid Content in Coconut Oil and Palm Oil under Different Heating Temperature Treatments using Reflectance–Fluorescence-based computer vi... by Luluk Oktaviana, Wahyunanto Agung Nugroho, Dimas Firmanda Al Riza Al Riza

“…A classification model was developed using a Convolutional Neural Network (CNN) algorithm to automatically extract color features contributing to oil quality classification. …”
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Long-term behaviour of non-functioning pituitary microadenomas: experience from a tertiary care centre in Romania by Mădălina Elena Iftimie, Mădălina Elena Iftimie, Iulia Florentina Burcea, Iulia Florentina Burcea, Ramona Dobre, Ramona Dobre, Stella Pigni, Flavia Prodam, Cătălina Poiană, Cătălina Poiană

“…This study aims to characterize the natural history of conservatively treated micro-NFPAs and provide evidence for a management algorithm.MethodsRetrospective, single center cohort study that analyzed clinical, hormonal and imaging data of conservatively managed micro-NFPAs (years 2018-2023).Results371 patients with micro-NFPAs were included in the study (mean age at diagnosis 41.26 ± 13.71 years, 91.6% females) with a mean tumor size at detection of 5.51 ± 1.95 mm. …”
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Predicting distant metastasis of bladder cancer using multiple machine learning models: a study based on the SEER database with external validation by Xin Chang Zou, Xue Peng Rao, Jian Biao Huang, Jie Zhou, Hai Chao Chao, Tao Zeng

“…Features were filtered using the least absolute shrinkage and selection operator (LASSO) regression algorithm. Based on the significant features identified, three ML algorithms were utilized to develop prediction models: logistic regression, support vector machine (SVM), and linear discriminant analysis (LDA). …”
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Evaluation of proton and carbon ion beam models in TReatment Planning for Particles 4D (TRiP4D) referring to a commercial treatment planning system by Yinxiangzi Sheng, Lennart Volz, Weiwei Wang, Marco Durante, Christian Graeff

“…Cubic plans with different depths in a water-tank phantom (WP) and previously treated and experimentally verified patient plans from SyngoRT were recalculated in TRiP4D. …”
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Eco-friendly QbD-optimized chromatographic method for simultaneous analysis of metronidazole and nicotinamide with applications in permeation, stability, and sustainability evaluat... by Kanaka Parvathi Kannaiah, Mohamed A. M. Ali, Hemanth Kumar Chanduluru, Anis Ahmad Chaudhary, Mahmoud El-Maghrabey, Reem H. Obaydo, Galal Magdy, Mohamed A. El Hamd

“…Abstract Metronidazole (MTZ) and nicotinamide (NCT) are co-formulated in Anaero® gel to treat skin conditions like acne and rosacea through combined antimicrobial and anti-inflammatory effects. …”
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Consumption of carotenoids not increased by bacterial infection in brown trout embryos (Salmo trutta). by Lucas Marques da Cunha, Laetitia G E Wilkins, Laure Menin, Daniel Ortiz, Véronique Vocat-Mottier, Claus Wedekind

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Modeling human early otic sensory cell development with induced pluripotent stem cells. by Hanae Lahlou, Alejandra Lopez-Juarez, Arnaud Fontbonne, Emmanuel Nivet, Azel Zine

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Lack of acquired resistance in HER2-positive breast cancer cells after long-term HER2 siRNA nanoparticle treatment. by Shenda Gu, Worapol Ngamcherdtrakul, Moataz Reda, Zhi Hu, Joe W Gray, Wassana Yantasee

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Systematic elucidation of the effective constituents and potential mechanisms of Scrophulariae Radix against neoplasm based on LC-MS, network pharmacology, and molecular docking ap... by Shu-jie Yu, Xiao-bin Kong, Xin Jin, Meng-yi Shan, Gang Cheng, Pei-lu Wang, Wen-long Li, Pei-yuan Zhao, Yun-jie Sheng, Bing-qian He, Qi Shi, Hua-qiang Li, Qi-ming Zhao, Lu-ping Qin, Lu-ping Qin, Xiong-yu Meng, Xiong-yu Meng

“…Scrophulariae Radix is a traditional Chinese medicine used to treat neoplasms in previous publications. Nevertheless, how the Scrophulariae Radix chemical constituents treat neoplasm still needs to be clarified. …”
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REinforcement learning to improve non-adherence for diabetes treatments by Optimising Response and Customising Engagement (REINFORCE): study protocol of a pragmatic randomised tria... by Lily G Bessette, Elad Yom-Tov, Niteesh K Choudhry, Julie C Lauffenburger, Nancy Haff, Marie E McDonnell, Constance P Fontanet, Ellen S Sears, Erin Kim, Kaitlin Hanken, Renee A Barlev, Punam A Keller, J Joseph Buckley

“…The messages will be individually adapted using a reinforcement learning prediction algorithm based on daily adherence measurements from the pill bottles. …”
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Reconstructed dose and geometric coverage for tight margins using intrafraction re-planning on an integrated magnetic resonance imaging and linear accelerator system for prostate c... by Ingeborg van den Berg, Cornel Zachiu, Eline N. de Groot-van Breugel, Thomas Willigenburg, Gijsbert H. Bol, Jan J.W. Lagendijk, Bas W. Raaymakers, Harm H.E. van Melick, Cornelis A.T. van den Berg, Jochem R.N. van der Voort van Zyp, Johannes C.J. de Boer

“…This study assessed geometric and reconstructed dose outcomes in patients treated with a tight-margin sub-fractionation workflow on a combined linear accelerator with a 1.5 T MRI scanner (MR-Linac). …”
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Norepinephrine use in cardiogenic shock patients is associated with increased 30 day mortality by Xin Lu, Xue Wang, Yanxia Gao, Joseph Harold Walline, Shiyuan Yu, Zengzheng Ge, Mubing Qin, Huadong Zhu, Yi Li

“…After PSM, 222 cases from each group were matched using a 1:1 matching algorithm. Thirty day mortality for patients treated with norepinephrine was significantly higher than for those in the non‐norepinephrine group (41% vs. 30%, OR 1.61, 95% CI 1.09–2.39, P = 0.017; HR 1.50, 95% CI 1.09–2.06, P = 0.013). …”
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THE RESULTS OF THE USE OF SELENIUM IN THE COMPLEX TREATMENT OF PATIENTS WITH CHRONIC GENERALIZED PERIODONTITIS by A.E. Gorshkova

“…The patients of the first group with chronic generalized periodontitis were treated according to the traditional scheme. Patients of the second group with chronic generalized periodontitis were treated according to a similar algorithm with an additional usage of an oily solution of retinol acetate, topically applied α-tocopherol acetate, ascorbic acid by ultrafonophoresis. …”
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Molecular Classification of Large B-Cell Lymphoma and High-Grade B-Cell Lymphoma Cases and Association with Outcomes in Morocco by Mahat Taybi, Zineb Khammar, Noufissa Alami Drideb, Rhizlane Berrady, Sanae Benmiloud, Laila Bouguennouch, Sanae Elfakir, Laila Tahiri, Mohammed Majdoub, Laila Chbani, Nawal Hammas

“…<b>Results:</b> Among the 50 cases studied in our population, we found 5 cases of HGBL with DLBCL morphology and 45 cases of DLBCL, which consisted of 13 cases (28.89%) of GCB subtype and 32 cases (71.11%) of non-GCB subtype based on the immunohistochemistry Hans algorithm. After FISH testing of all cases, we found three cases of double-hit lymphoma (DHL) and one case of triple-hit lymphoma (THL). …”
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Are treatment plans optimized on the basis of acuros XB dose calculation robust against anatomic changes during online adaptive radiotherapy for lung cancer regarding dose homogene... by Khouya Aymane, Santiago Alina, Ringbaek Toke, Guberina Nika, Guberina Maja, Gauler Thomas, Lübcke Wolfgang, Zylka Waldemar, Pöttgen Christoph, Stuschke Martin

“…Abstract Introduction The Acuros XB dose calculation algorithm implements advanced modelling of lateral electron transport, making dose distributions sensitive to density changes between source and subsequent CT. …”
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Potential Herb-Drug Interactions Among Elderly Nursing Home Residents in Romania by Hanna Sebesi, László István Bába, Melinda Kolcsár, Zsolt Gáll, Soma Dávid

“…AIM: Our study investigates the algorithm-predicted HDIs during herb-drug coadministration among elderly patients in nursing homes in a Romanian sample. …”
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COVID-19 Vaccination and Transient Increase in CD4/CD8 Cell Counts in People with HIV: Evidence from China by Yanyan Li, Yingying Lin, Yunyun Yi, Na Zhu, Xinyu Cui, Xin Li

“…<b>Methods</b>: A total of 372 PWH treated at Beijing Ditan Hospital were included. Unvaccinated PWH were matched 1:3 with vaccinated PWH using a propensity score matching algorithm. …”
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