Improved Coulomb collision operator for kinetic ion transport with EMC3-EIRENE simulating Nitrogen seeding in medium density ITER L-mode scenario by D. Harting, D. Reiser, S. Rode, J. Romazanov, P. Börner, Y. Feng, H. Frerichs, A. Knieps

“…The Fokker-Planck equation is treated by an operator splitting scheme and is solved locally by a Monte-Carlo method. …”
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Temporal changes in blood biomarkers associated with sleep apnoea severity: a retrospective cohort study in Finland by Satu Strausz, Sanna Toppila-Salmi, Tuula Vasankari, Hanna M Ollila, Mira Hellen, Toni Ruoranen, Hanna-Riikka Kreivi, Tiina Mattila

“…This study aims to investigate the effect of continuous positive airway pressure (CPAP) therapy on laboratory values in patients with OSA.Methods A retrospective study was conducted using data from Finland’s largest hospital district, including 30 722 adult OSA patients treated between 2005 and 2020. A text search algorithm was implemented within the patient chart data to extract the apnoea-hypopnoea index (AHI) and the usage of CPAP therapy, along with identifying patients who had declined treatment. …”
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Practical application of national clinical guidelines for the management of gout (preliminary data) by M. N. Chikina, M. S. Eliseev, O. V. Zhelyabina

“…The 2018 national guidelines for the management of gout provide a consistent scheme for urate-lowering drugs; however, the possibility of achieving uric acid (UA) targets in its use has not been studied.Objective: to evaluate the effectiveness and safety of the urate-lowering therapy algorithm presented in the national guidelines for the management of gout.Patients and methods. …”
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Deep learning-assisted analysis of biomarker changes after increase of dosing from aflibercept 2 mg to 8 mg in therapy-resistant neovascular age-related macular degeneration by Siegfried Priglinger, Jakob Siedlecki, Benedikt Schworm, Franziska Eckardt, Michael Hafner, Ben Asani, Caspar Liesenhoff, Alexander Kufner, Johannes Benedikt Schiefelbein

“…Since 01/2024, aflibercept 8 mg represents an additional treatment option and contains a four times higher dosage than the already known aflibercept 2 mg.Methods To evaluate the real-world efficacy of aflibercept 8 mg in refractory nAMD patients, focusing on changes in key optical coherence tomography biomarkers over a follow-up period of the first four aflibercept 8 mg injections using a deep learning-based semantic segmentation algorithm. Inclusion criteria were: switch to aflibercept 8 mg after insufficient response to aflibercept 2 mg, marked by persistent retinal fluid or inability to extend treatment beyond 6 weeks; completion of at least 3 months (90 days) follow-up under treat-and-extend treatment regime; and no confounding conditions like intraocular infection, uveitis or other retinal diseases.Results 23 eyes of 21 patients with therapy-resistant nAMD were switched to aflibercept 8 mg. …”
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Building radiomics models based on ACR TI-RADS combining clinical features for discriminating benign and malignant thyroid nodules by Xingxing Chen, Xingxing Chen, Lili Zhang, Bin Chen, Jiajia Lu

“…A total of 107 radiomics features were extracted from the US images, and the radiomics score (Rad-score) was constructed using the Least Absolute Shrinkage and Selection Operator (LASSO) algorithm. Different models were created using logistic regression, including the clinic-ACR score (Clin+ACR), clinic-Rad score (Clin+Rad), ACR score-Rad score (ACR+Rad), and combined clinic-ACR score-Rad score (Clin+ACR+Rad). …”
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Simplification of the diagnostic approach and treatment of Hepatitis C Virus. by Clara C. Sanchez-Rodriguez, Ana M. Mendoza-Martínez, Héctor R. Sánchez-Nuncio, Jorge H. Luna-Domínguez

“…Fibrosis was calculated using the APRI algorithm, finding 53/130 with >1.5 and 60/130 with >3.25, which predicted F3-4. …”
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In vitro machine learning-based CAR T immunological synapse quality measurements correlate with patient clinical outcomes. by Alireza Naghizadeh, Wei-Chung Tsao, Jong Hyun Cho, Hongye Xu, Mohab Mohamed, Dali Li, Wei Xiong, Dimitri Metaxas, Carlos A Ramos, Dongfang Liu

“…The ML-based automated algorithm quantified CAR-T IS data correlates with the clinical responder and non-responder treated with Kappa-CAR-T cells directly from patients. …”
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Endothelial Dysfunction, Functional Structural Changes in the Vessels in Patients with the Unstable Angina with Arterial Hypertension by Denesiuk O.

“…The initial diameter of the brachial artery, the reaction to hyperemia, which was treated as endothelium-dependent vasodilation, was determined. …”
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Chronic Abdominal Discomfort Syndrome (CADS): A Narrative Review of Treatment Strategies by Gupta M, Patil AS, Staats P, Schatman ME, Kalia H, Sayed D, Soin A, Baranidharan G, Kapural L, Chitneni A, Verrills P, Diwan S, Abd-Elsayed AA, Deer TR

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Effect of Achieving Sustained SDAI Remission on Erosion Healing in Early Rheumatoid Arthritis - A One-year Prospective HR-pQCT Study by Qihan Wu, Ho So, Tsz-Ho Cheng, Yingzhao Jin, Sze-Lok Lau, Lai-shan Tam

“…Methods Patients with ERA were recruited and treated to the target of simple disease activity index (SDAI) remission using a standardized algorithm. …”
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Bidirectional Relationship Between Hypoalbuminemia and Postoperative Pneumonia in Elderly Hip Fracture Patients: A Retrospective Cohort Study by Wang J, Yu H, Xu X, Guo J

“…After predefined participants selection inclusion and exclusion criteria, 1661 surgically treated HF patients were included and analyzed utilizing multiple statistical models, including univariate logistic regression, Lasso regression, and Boruta algorithm for variable selection, while multivariate logistic regression and propensity score matching (PSM) for assess the bidirectional relationship between hypoalbuminemia and postoperative pneumonia. …”
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Radiomics to predict tumor response to combination chemoradiotherapy in squamous cell carcinoma of the anal canal: a preliminary investigation by Andrea Vanzulli, Lucilla Violetta Sciacqua, Filippo Patti, Roza Drebot, Eros Montin, Riccardo Lattanzi, Laura Anna Maria Lozza, Sergio Villa, Davide Scaramuzza

“…We report the preliminary results of a customized radiomic algorithm designed to predict tumor response to CRT in patients affected by SCC of the anal canal. …”
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Surgical management of peripheral nerve symptoms following knee arthroplasty by Otis C. van Varsseveld, Floris V. Raasveld, Wen-Chih Liu, Justin McCarty, Caroline A. Hundepool, J. Michiel Zuidam, Ian L. Valerio, Kyle R. Eberlin

“…Results Twenty-seven lower extremities treated in 26 patients with a median age of 67.0 years (IQR: 58.0–71.8) were included. …”
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The Impact of an Adaptive mHealth Intervention on Improving Patient-Provider Health Care Communication: Secondary Analysis of the DIAMANTE Trial by Lynn Leng, Marvyn R Arévalo Avalos, Adrian Aguilera, Courtney R Lyles

“…Our primary analysis used mixed-effects modeling within an intent-to-treat analysis to determine differences in CAHPS scores by trial arm. …”
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Characteristics and outcomes of patients with LAM receiving sirolimus in France based on real-life data by Vincent Cottin, Vincent Cottin, Antoine Cases, Virginie Bourdin, Martine Reynaud-Gaubert, Sandrine Hirschi, Mallorie Kerjouan, Rémi Diesler, Rémi Diesler, Brieux Chardès, Stéphane Fiévez, Nada Assi, Aurélie Schmidt, Hélène Denis, Lidwine Wémeau-Stervinou, Yurdagul Uzunhan

“…In the absence of a specific LAM code in the system, an algorithm was developed to identify patients treated for possible LAM exclusion of other sirolimus indications (transplantation, graft-versus-host disease), or probable LAM (among possible LAM, patients hospitalized for pneumothorax, pleural drainage, pleurisy, ascites, chronic respiratory failure, lung transplantation, or angiomyolipoma). …”
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The PKC-β selective inhibitor, Enzastaurin, impairs memory in middle-aged rats. by Mari N Willeman, Sarah E Mennenga, Ashley L Siniard, Jason J Corneveaux, Matt De Both, Lauren T Hewitt, Candy W S Tsang, Jason Caselli, B Blair Braden, Heather A Bimonte-Nelson, Matthew J Huentelman

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Nomogram model using serum Club cell secretory protein 16 to predict prognosis and acute exacerbation in patients with idiopathic pulmonary fibrosis by Yaqiong Tian, Xuan Zhou, Mi Tian, Lijun Ren, Ruyi Zou, Hanyi Jiang, Miaomiao Xie, Mei Huang, Jingjing Ding, Yin Liu, Jingyu Chen, Min Cao, Hourong Cai

“…COX regression and LASSO algorithm were used to screen featured characteristics. …”
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COVID-19’s Influence on Ocular Emergency Visits at a Tertiary Referral Center and Its Relationship to Emergency Indications by the American Academy of Ophthalmology by Sharon Armarnik, Michael Kinori, Amir Abd Elkader, Sharon Blum Meirovitch, Noa Kapelushnik, Shiran Madgar, Hila Goldberg, Oded Sagiv, Tamara Wygnanski-Jaffe, Ayelet Priel

“…Our change in the treatment algorithm was in agreement with the AAO recommendations during the pandemic.…”
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Aggregation-Based Ensemble Classifier Versus Neural Networks Models for Recognizing Phishing Attacks by Wojciech Galka, Jan G. Bazan, Urszula Bentkowska, Kamil Szwed, Marcin Mrukowicz, Pawel Drygas, Lech Zareba, Marcin Szpyrka, Piotr Suszalski, Sebastian Obara

“…The main advantage of the proposed algorithm is achieving high numbers of true positives while simultaneously achieving relatively small number of false positives. …”
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Peptide receptor radionuclide therapy for ectopic Cushing’s syndrome caused by metastatic neuroendocrine neoplasms by Emma Boehm, Terry Hung, Tim Akhurst, Ramin Alipour, Cherie Chiang, Rodney J Hicks, Michael S Hofman, Aravind S Ravi Kumar, Nirupa Sachithanandan, Javad Saghebi, Michael Michael, Grace Kong

“…Aim: To describe the characteristics and outcomes of patients with ECS treated with PRRT. Methods: Single-centre, retrospective analysis of imaging, biochemistry and outcomes of seven consecutive patients with ECS caused by metastatic GEPNEN treated with PRRT from 2006 to 2023. …”
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