Treatment for rheumatic polymyalgia by Azamat Makhmudovich Satybaldyev

“…Glucocorticosteroids (GCs) that provide a good and rapid clinical effect are the drug of choice to treat rheumatic polymyalgia (RP). A review of English language publications on the treatment of RP is given. …”
Get full text

Smooth Local Interpolation of Surfaces Using Normal Vectors by Takashi Nagata

“…The methodology presented in this paper inherits most of the advantages possessed by the 𝐶0 scheme. That is, (i) The algorithm is efficient and completely local requiring only the position vectors and normals given at the nodes of a patch, and hence it is suitable for parallel processing. …”
Get full text

A Study of Mixed Non-Motorized Traffic Flow Characteristics and Capacity Based on Multi-Source Video Data by Guobin Gu, Xin Sun, Benxiao Lou, Xiang Wang, Bingheng Yang, Jianqiu Chen, Dan Zhou, Shiqian Huang, Qingwei Hu, Chun Bao

“…The video data were processed with an image detection algorithm based on the YOLO convolutional neural network and a video tracking algorithm using the DeepSORT multi-target tracking model, extracting data on traffic flow, density, speed, and rider characteristics. …”
Get full text

Surgical Hemostasis for Severe Multisystem Pelvic Injuries by I. V. Kazhanov, A. Y. Demko, V. A. Manukovsky, S. I. Mikityuk, V. A. Reva, E. A. Kolchanov, D. V. Pavlov

“…For the treatment of patients with severe multysistem pelvic trauma accompanied by pelvic bleeding, many algorithms have been proposed that have different procedures for the use of various methods of surgical hemostasis, but none of them may guarantee the complete arrest of pelvic bleeding. …”
Get full text

Risk Prediction of Liver Injury in Pediatric Tuberculosis Treatment: Development of an Automated Machine Learning Model by Zeng Y, Lu H, Li S, Shi QZ, Liu L, Gong YQ, Yan P

“…The area under the receiver operating characteristic curve (AUC) was used to evaluate model’s performance, and then the TreeShap algorithm was employed to interpret the variable contributions.Results: A total of 184 children were enrolled in this study, of whom 19 (10.33%) developed ATB-DILI. …”
Get full text

Real-world phosphorodiamidate morpholino oligomer treatment patterns in Duchenne muscular dystrophy: a claims-based analysis by Shannon Grabich, Brian Ung, Aalok Nadkar, Kathryn DeYoung, James Signorovitch, Aravindhan Veerapandiyan

“…Treatment patterns were also assessed in patients stratified by baseline algorithm-defined nonambulatory status (inferred from claims). …”

Predicting Bleeding Events in Anticoagulated Patients With Atrial Fibrillation: A Comparison Between the HAS‐BLED and GARFIELD‐AF Bleeding Scores by Marco Proietti, José Miguel Rivera‐Caravaca, María Asunción Esteve‐Pastor, Giulio Francesco Romiti, Francísco Marin, Gregory Y. H. Lip

“…Background Patients with atrial fibrillation (AF) treated with oral anticoagulants may be exposed to an increased risk of bleeding events. …”
Get full text

Advancements in the application of artificial intelligence in the field of colorectal cancer by Mengying Zhu, Mengying Zhu, Zhenzhu Zhai, Yue Wang, Fang Chen, Ruibin Liu, Ruibin Liu, Xiaoquan Yang, Guohua Zhao

“…AI, utilizing machine learning (ML) and deep learning (DL) algorithms, improves early detection, diagnosis, and treatment by processing large volumes of medical data, uncovering hidden patterns, and forecasting disease development. …”
Get full text

An in silico evaluation of lorlatinib as a potential therapy for novel amino acid substitutions in the tyrosine kinase domain of the ALK protein associated with cancer by Richard Junior Zapata Dongo, Julio A. Poterico, Diletta Fontana, Luca Mologni, Carla Alvarez-Chacon, Juan Rojas-Armas, Jaeson Calla

“…Using the SIFT and Polyphen-2 algorithms, we identified 53 deleterious ALK mutations associated with different newly recognized cancer types. …”
Get full text

Application of Multistage Homotopy Perturbation Method to the Chaotic Genesio System by M. S. H. Chowdhury, I. Hashim, S. Momani, M. M. Rahman

“…The MHPM is a simple reliable modification based on an adaptation of the standard homotopy-perturbation method (HPM). The HPM is treated as an algorithm in a sequence of intervals for finding accurate approximate solutions to the Chaotic Genesio system. …”
Get full text

Fluocinolone acetonide 0.2 µg/day intravitreal implant in non-infectious uveitis affecting the posterior segment: EU expert user panel consensus-based clinical recommendations by Uwe Pleyer, Carlos Pavesio, Elisabetta Miserocchi, Carsten Heinz, Helen Devonport, Víctor Llorenç, Tomás Burke, Vanda Nogueira, Laurent Kodjikian, Bahram Bodaghi

“…The aim here was to provide treating clinicians with some consensus-based-recommendations for the clinical management of patients with NIU-PS with 0.2 µg/day FAc implants. …”
Get full text

Identification of key programmed cell death genes for predicting prognosis and treatment sensitivity in colorectal cancer by Jian-ying Ma, Jian-ying Ma, Yi-xian Wang, Zhen-yu Zhao, Zhen-yu Xiong, Zi-long Zhang, Jun Cai, Jia-wei Guo

“…Unsupervised clustering algorithms were used to identify two molecular subtypes of CRC with distinct features. …”
Get full text

Uterine hydatidosis: casuistry is possible by A. L. Tikhomirov, V. V. Kazenashev, A. A. Dubinin, R. R. Sadikova, M. V. Maminova, J. S. Globa, A. V. Bukharov

“…Compared with common gynecological disease such as uterine fibroids, ovarian cyst and malignancies uterine hydatidosis may be identified only in 0.16 % cases.Aim: to present a clinical case of uterine hydatid cyst in order to optimize algorithms for differential diagnosis of primary pelvic echinococcosis and gynecological pathology, which is necessary for successfully conducted timely surgical treatment.Clinical case. …”
Get full text

Design of Low-Power Structural FIR Filter Using Data-Driven Clock Gating and Multibit Flip-Flops by Lamjed Touil, Abdelaziz Hamdi, Ismail Gassoumi, Abdellatif Mtibaa

“…Data-driven clock gating (DDCG) and multibit flip-flops (MBFFs) are two low-power design methods that are used and often treated separately. The combination of these methods into a single algorithm enables further power saving of the FIR filter. …”
Get full text

Brodalumab for Moderate-to-Severe Psoriasis: A Comprehensive Review of Efficacy, Safety, and Clinical Positioning by Babaei N, Gill M, Cervantes M, Kim D, Yang S, Wu JJ

“…Further research is warranted to better define its role in treatment algorithms and to assess long-term outcomes in broader patient populations.Keywords: brodalumab, psoriasis, Il-17RA, psoriasis treatment…”
Get full text

Derotational osteotomy is a relevant procedure in the management of lateral patellar dislocation: An expert survey of the International Patellofemoral Study Group by Guido Wierer, Danko Milinkovic, Gerd Seitlinger, Michael Liebensteiner, William Post, Philipp W. Winkler

“…Abstract Purpose To evaluate current knowledge and discover potential controversies in treating torsional deformities of the lower limb in patients with lateral patellar dislocation (LPD) among patellofemoral experts. …”
Get full text

How real is the long-lasting effect of tumor necrosis factor α inhibitors? Focus on immunogenicity by D.E. Karateev

“…Tumor necrosis factor (TNF) α inhibitors are the most commonly used agents to treat rheumatoid arthritis (RA) and other inflammatory arthropathies. …”
Get full text

Identification of gene signatures and potential pharmaceutical candidates linked to COVID-19-related depression based on gene expression profiles by Shaojun Chen, Yiyuan Luo, Lihua Zhang

“…Subsequently, we employed two machine learning analyses—least absolute shrinkage and selection operator (LASSO) and random forest algorithms– to pinpoint shared hub gene between the two diseases. …”
Get full text

Unveiling the role of oxidative stress in ANCA-associated glomerulonephritis through integrated machine learning and bioinformatics analyses by Liyuan Xie, Xianying Qiu, Junya Jia, Tiekun Yan, Pengcheng Xu

“…This study offers novel insights into immune-associated OSRGs within the glomerular and tubulointerstitial compartments of AAGN which may serve as innovative targets for diagnosing and treating AAGN.…”
Get full text

Diagnosing facial synkinesis using artificial intelligence to advance facial palsy care by Leonard Knoedler, Christian Festbaum, Jillian Dean, Helena Baecher, Grégoire de Lambertye, Maximilian Maul, Thomas Schaschinger, Tobias Niederegger, Alexandra Scheiflinger, Michael Alfertshofer, Khalil Sherwani, Claudius Steffen, Max Heiland, Steffen Koerdt, Samuel Knoedler, Andreas Kehrer

“…This involuntary simultaneous movement of facial musculature remains challenging to diagnose and treat. This study aimed to develop a cost-effective, rapid, and accurate artificial intelligence (AI)-based algorithm to screen FP patients for facial synkinesis. …”
Get full text