Presentations to Emergency Departments for COPD: A Time Series Analysis by Rhonda J. Rosychuk, Erik Youngson, Brian H. Rowe

“…ED presentations for COPD totalled 188,824 and the monthly rate of presentation remained relatively stable (from 197.7 to 232.6 per 100,000). …”
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Sparse high-dimensional decomposition of non-primary auditory cortical receptive fields. by Shoutik Mukherjee, Behtash Babadi, Shihab Shamma

“…Such CortRF analysis was applied to PEG neuronal responses to speech and temporally orthogonal ripple combination (TORC) stimuli and, for comparison, to A1 neuronal responses. …”
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Study on the safety and efficacy of HIFU in the treatment of VaIN by Susu Wu, Xiang Li, Dabao Xu, Mingzhu Ye

“…All patients successfully completed the HIFU treatment, with an average treatment time of 5.99 ± 1.25 min, treatment power of 3.5 W, and average total treatment dose of 1118.99 ± 316.20 J. Patients tolerated the treatment well, experiencing only slight pain with VAS score of 3. …”
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Site-specific immunoglobulin G N-glycosylation is associated with gastric cancer progression by Tingting Xu, Jianmin Huang, Jiajing Lin, Yuanyuan Liu, Yi Wang, Wenkang Shen, Jianjie He, Shuyun Chen, Xi Zhu, Yuqin Que, Mengting Hu, Yu Chen, Liming Cheng, Honghao He, Xin Liu, Si Liu

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Flexural Design and Analysis of Composite Beams with Inverted-T Steel Girder with Ultrahigh Performance Concrete Slab by Wonchang Choi, Youngcheol Choi, Sung-Won Yoo

“…This study intends to improve the efficiency of the composite beam combining a slab made of steel fiber-reinforced ultrahigh performance concrete (UHPC) and a steel girder without top flange. To that goal, the experiment is conducted on 24 composite beams fabricated with varying compressive strength of UHPC, steel fiber content, stud spacing, and slab thickness to evaluate the behavior of the studs and the flexural behavior of the composite beam combining the UHPC slab and the inverted-T steel girder. …”
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Influence of Urban Development on Extreme Precipitation in Plateau Lake Basin by LI Baofen, LI Xiaopeng, CAO Yimei, JIN Zhuo

“…Studying the influence of urban development on extreme precipitation in the lake basin region is of practical significance for urban flood control and disaster reduction,forecasting and early warning capability increase and emergency response capacity building,“four pres” improvement,and risk tackling of extreme precipitation and waterlogging disasters.Taking Kunming,a city in the Yunnan Plateau Basin,as an example,this paper adopts mathematical statistical methods to analyze the effect of urban development on the extreme precipitation index in the central urban area of the lake basin,the basin edges,and peripheral hilly areas of the city.The results show that urban development exerts different degrees of influence on various extreme precipitation indexes in lake basin areas,basin edges,and peripheral hilly areas of the basin, with the strongest,weakest,and middle effects on the basin edges, hilly areas,and lake basin areas respectively.Due to topography and the urban heat island effect,urban development also causes uneven increase and decrease in the extreme precipitation index in various areas such as lake basin areas,basin edges,and hilly areas.…”
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Novel features of asymmetric nuclear matter from terrestrial experiments and astrophysical observations of neutron stars by Tsuyoshi Miyatsu, Myung-Ki Cheoun, Kyungsik Kim, Koichi Saito

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Formation and development of the Acquis Communautaire in France, Germany and Switzerland: A comparative legal analysis by N. O. Rastorhuieva

“…On the basis of and through the disclosure of the concept of “acquis communautaire”, the diversity of its understanding within different approaches and the nature of this phenomenon, as well as the study of the formation of the acquis communautaire specifics, it is established that this process took place in the course of formation of the European Communities in the 1950s with the participation of France and Germany on the basis of a combination of liberal market and general social values, and its development took place during the elaboration of the foundations of the mechanism for adoption of a common European policy. …”
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National and subnational plans for primary prevention and early detection of oral and oropharyngeal cancer: a scoping review by Marcia Frias Pinto Marinho, Maria Clara Frias Lobo Marinho, Guido Artemio Marañón-Vásquez, Keith Bullia da Fonseca Simas, Mário José Romañach, Aline Corrêa Abrahão, Maria Augusta Visconti Rocha Pinto, Lucianne Cople Maia de Faria, Michelle Agostini

“…Western Pacific and Eastern Mediterranean regions had the lowest coverage with 24.2% and 23.8%, respectively. Tobacco use was the most discussed oral and oropharyngeal cancer risk factor in primary prevention plans (63.7%), followed by HPV infection (54%) and alcohol consumption (35.5%). …”
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Decoupling Relationship Between Water Resources Utilization and Economic Development in Henan Province Based on Water Footprint-Extended LMDI Model by LU Qiuyu

“…Aiming at the related problems of water resources constraining economic development in Henan Province,this paper constructs the water footprint-extended LMDI model,decomposes the decoupling driving factors into four decoupling factors,and studies the decoupling relationship between water resources utilization and economic development in Henan Province from 2004 to 2018.The results show that:In terms of the possession and self-sufficiency rate of total per capital water footprint,the overall water shortage in Henan Province has been alleviated,but it is still in a state of shortage;In terms of decoupling state,the overall decoupling of Henan Province is in a good statel,the decoupling state of agricultural water is relatively stable,and the hydrological year has an impact on the agricultural virtual water consumption and decoupling state;In terms of decoupling factor decomposition,the technological decoupling factor contributes to the decoupling in Henan Province,the industrial structure and scale economy are the main promoting and inhibiting factors of decoupling,respectively,and the change of population driving factor has no obvious inhibiting effect on decoupling in Henan Province.Therefore,it is necessary to improve the utilization efficiency of water resources,the repetition rate of industrial water use,and improve the agricultural irrigation water-saving technology in Henan Province.…”
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Drawing the future: gender and future occupational aspirations of young children in Sweden by Sarah Wamala-Andersson, Matt X. Richardson, Karin Schölin Bywall, Therese Norgren, Nick Chambers

“…Girls preferred people- or animal-centered roles, while boys leaned toward jobs involving “things” (p < 0.001). Girls felt they could pursue similar careers as boys, but boys showed more skepticism (p < 0.001). …”
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Regulatory role of S1P and its receptors in sepsis-induced liver injury by Bin Wang, Bin Wang, Xiaoyu Wu, Xiaoyu Wu, Jiangfeng Cheng, Jiangfeng Cheng, Junming Ye, Junming Ye, Hongquan Zhu, Hongquan Zhu, Xiaofeng Liu, Xiaofeng Liu

“…Sphingosine-1-phosphate (S1P) is a widely distributed lipid signaling molecule that binds to five sphingosine-1-phosphate receptors (S1PR) to regulate downstream signaling pathways involved in the pathophysiological processes of sepsis, including endothelial permeability, cytokine release, and vascular tone. This review summarizes current research on the role of S1P in normal liver biology and describes the mechanisms by which changes in S1P/S1PR affect the development of liver-related diseases. …”
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Effect of Berberine on the Inflammatory Response of ANA-1 Cells Induced by Angiotensin Ⅱ Based on TLR4 Signaling Pathway by GAO Dexing, JIA Peizhi, PENG Jun, LIN Wei

“…Cell proliferation and toxicity test (CCK-8) was used to detect the effect of different concentrations of BBR on cell viability; the flow cytometry was used to detect the mean fluorescence intensity (MFI) of TLR4 on cell membrane ; ELISA method was used to detect the content of interleukin-1β (IL-1β), interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α); the real-time quantitative PCR was used to detect the mRNA level of IL-1β, IL-6, TNF-α; Western blot was used to detect the phosphorylation of p-ERK/ERK, p-p38/p38, p-JNK/JNK, p-p65/p65 and p-IRF3/IRF3 and the expression of TLR4, MyD88 and AP-1; the biochemical assay was used to detect the content of malondialdehyde (MDA) and the activity of superoxide dismutase (SOD).Results① CCK-8 assay results: compared with the control group, there was no significant difference in cell activity of the low, medium and high- dose BBR group, the difference was not statistically significant (<italic>P</italic>&gt;0.05). ② Flow cytometry results: compared with the fluorescent antibody group, MFI of the model group was significantly decreased; compared with the model group, MFI of the model group + the high dose BBR group was significantly increased, the difference was statistically significant (<italic>P</italic>&lt;0.05). ③ ELISA results: compared with the control group, the content of IL-1β, IL-6, TNF- α of the model group was significantly increased; compared with the model group, the content of IL-1β, IL-6, TNF- α of the model group + the low, medium and high dose BBR group was significantly decreased, the difference was statistically significant (<italic>P</italic>&lt;0.05). ④ Real-time quantitative PCR results: compared with the control group, the mRNA level of IL-1β, IL-6, TNF-α of the model group was significantly increased; compared with the model group, the mRNA level of IL-1β, IL-6, TNF- α of the model group + the low, medium and high-dose BBR group was significantly decreased, the difference was statistically significant (<italic>P</italic>&lt;0.05). ⑤ Western blot results: compared with the control group, the phosphorylation expression of p65 and IRF-3 protein of the model group after intervention for 45 minutes was significantly increased, and the phosphorylation expression of p65, IRF-3 protein in the model group + the low, medium and high-dose BBR group was significantly decreased. …”
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Rusçuk Çiftlikleri ve Çiftlik Piyasasında Eski Aktörler, Yeni Figürler by Ahmet İlker BAŞ

“…Çiftlik is the one of the most important debate topics in Ottoman agricultural history. While they are generally evaluated under the topics of landownership and legal status of peasants in the context of centrifugal forces, as a commodity, the exchange of çiftliks in the real estate market does not attract scholars’ attention enough. …”
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Problema protocronismului. Precizări by Edgar Papu

“…This theory scored a new axiological attitude towards the Romanian literature, remaining a possible guide-line in re-assessing the history of ideas.…”
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A study of the user experience while working with mobile applications cooperating with sports bands by Szymon Czopek, Mariusz Dzieńkowski

“…Then, each participant took part in a survey. Task completion time, eye-tracking indicators (the number of fixations, fixation duration, the number of blinks), users’ evaluation and the level of diagnosed errors were used for comparative analysis. …”
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Thermal Arrest Memory Effect in Ni-Mn-Ga Alloys by A. Rudajevova

“…Interruption of the martensite-austenite phase transformation is connected with the reduction of the sample length after thermal cycle. If a total phase transformation took place in the complete thermal cycle following the interruption, then the sample length would return to its original length. …”
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Estimation of Alpha-Amylase in Smokers with and without Leukoplakia and Oral Cancer—A Comparative Study by Amit A. Basannavar, Ankita Bhargava, Alkananda Sahoo, Nidhi Dhakar, Rahul R. Shetty, Debanti Giri

“…Materials and Methods: A total of 150 male subjects were recruited for this comparative study and divided into three groups: 50 smokers without any oral lesions (group A), 50 smokers with leukoplakia (group B), and 50 smokers with oral cancer (group C). …”
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ردیابی سرولوژیکی و تعیین دامنه میزبانی ویروس مخطط توتون در استان گلستان by سعید نصرالله نژاد, سمیرا شاملی

“…استان گلستان یکی از مهم ترین مناطق کشت توتون در کشور می باشد. ویروس مخطط توتون Tobacco Streak Ilarvirus یکی از ویروس های مخرب توتون بوده که دارای دامنه میزبانی وسیع و گسترش جهانی است. …”
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Protective Effects of Gynostemma pentaphyllum Saponins on Liver Injury in Guinea Pigs of Hyperlipemia Based on Oxidative Stress by Tianyi DAI, Donglian LIU, Xingmin QIN, Chengling GAO, Jiayi LI, Hailing KUANG

“…After the experiment, the levels of total TC, TG, HDL and LDL of guinea pigs were measured. …”
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