UFMylation maintains YAP stability to promote vascular endothelial cell senescence by Yanan Liu, Min Zuo, Aiwei Wu, Zhaoxiang Wang, Siting Wang, Yongping Bai, Junzhi Zhou, Hu Wang

“…Importantly, we found that compound 8.5, an inhibitor of E1 of UFMylation, can alleviate vascular aging in aged mice. Together, our finding provides molecular mechanism by which UFMylation maintains YAP stability and exerts an important role in promoting cell senescence, and identified that a previously unrecognized UFMylation is a potential therapeutic target for anti-aging.…”
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Más allá de la Conexión: Evaluación Cuantitativa de la Conectividad Significativa en Estudiantes Universitarios de ciencias sociales bajo el Modelo A4IA (Beyond Connection: Quantit... by Paulo Gomez Zanabria, Manuel Higueras Matos, Eick Lazarte Lazarte Vera, URSULA ANGELA NOELIA PODESTÁ SÁNCHEZ

“…Se utilizó la fuente estadística sobre el “Diagnóstico de retorno a la presencialidad, semipresencialidad y/o virtual – Condiciones de Bioseguridad, Administrativos, Docentes y Estudiantes” generada por la Universidad Nacional de San Agustín Resultados: Se encontró información para los indicadores MC1 y MC2 pero no para los indicadores MC3 y MC4, debido a que estos datos no se tomaron en cuenta. Conclusiones: El servicio de conexión a Internet en los estudiantes de la UNSA aplicando la fórmula de la A4IA obtuvo una ponderación de 73%, en cuanto al indicador MC1. …”
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Determining the intention of receiving the influenza vaccine: a cross-sectional survey among international and domestic college students in the USA by Charles Liu, Jiying Ling, ChengChing Liu, Angela Chia-Chen Chen, Nagwan Zahry, Ravichandran Ammigan, Loveleen Kaur

“…This study examined the relationships between the theory of planned behaviour (TPB; attitudes, perceived behavioural control (PBC) and subjective norms) and students’ intention of receiving an influenza vaccine.Design, setting and participants A cross-sectional study was conducted with a convenience sample of 222 domestic students recruited via Amazon Mechanical Turk and 197 international students recruited through the Registrar’s Office at a Midwest university.Results International students had higher levels of PBC, intention and attitudes towards receiving an influenza vaccine compared with domestic students. …”
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Malvidin-3-galactoside from blueberry suppresses the growth and metastasis potential of hepatocellular carcinoma cell Huh-7 by regulating apoptosis and metastases pathways by Jie Lin, Jinlong Tian, Chi Shu, Zhen Cheng, Yunen Liu, Weisheng Wang, Ruihai Liu, Bin Li, Yuehua Wang

“…Regarding the metastasis potential, Mv-3-gal suppressed the migration and invasion potential of Huh-7 cells by regulating MMPs expression. Taken together, the findings highlighted the anti-HCC potent of Mv-3-gal, which was associated with the inhibition of Akt/PTEN, MAPK and MMP pathways.…”
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Descifrando a Yupanqui. Diario de una biografía by Sergio Pujol

“…El autor de estas notas reflexiona en torno a las dificultades y los desafíos que debió enfrentar a la hora de escribir la biografía de un personaje extremadamente “público” pero a la vez escurridizo; canónico pero también un poco secreto. …”
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Measuring plant cysteine oxidase interactions with substrates using intrinsic tryptophan fluorescence by Dona M. Gunawardana, Daisy A. Southern, Emily Flashman

“…The PCOs are potential targets for improving submergence tolerance through enzyme engineering or chemical treatment. …”
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Psychometric properties of a Serbian version of the State-Trait Anxiety Inventory X-2 by Damjan Jakšić, Jovana Trbojević Jocić, Stefan Maričić, • Bülent Okan Miçooğulları

“…A statistically significant difference between handball players of different competitive ranks appeared only on the Positive affect factor between the top athletes and the athletes in the second league (p = .04).…”
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Exergy Analysis in Hydrogen-Air Detonation by Abel Rouboa, Valter Silva, Nuno Couto

“…The energy balance shows a successive conversion of kinetic energy, and total enthalpy, however, does not indicate consequent losses. …”
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Separation and Determination of Fe(III) and Fe(II) in Natural and Waste Waters Using Silica Gel Sequentially Modified with Polyhexamethylene Guanidine and Tiron by Svetlana Didukh, Vladimir Losev, Elena Borodina, Nikolay Maksimov, Anatoly Trofimchuk, Olga Zaporogets

“…Procedures for separation and photometric determination of Fe(III) and Fe(II) at the joint presence and total Fe content determination as Fe(II) in waste and natural waters was developed. …”
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L-Ornithine L-Aspartate for the Treatment of Sarcopenia in Chronic Liver Disease: The Taming of a Vicious Cycle by Roger F. Butterworth

“…Randomized clinical trials and meta-analyses confirm that L-ornithine L-aspartate (LOLA) is an effective ammonia-lowering agent currently employed for the treatment of hepatic encephalopathy (HE) that stimulates both urea synthesis by residual hepatocytes and muscle glutamine synthesis together with putative hepatoprotective actions. Treatment of cirrhotic patients with LOLA limits ammonia-induced sarcopenia by improving muscle protein synthesis and function. …”
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Community perceptions of community health worker effectiveness: Contributions to health behaviour change in an urban health district in South Africa by L S Thomas, Y Pillay, E Buch

“…Community health worker (CHW) programmes contribute towards strengthening adherence support, improving maternal and child health outcomes and providing support for social services. …”
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Validity and Reliability of Kinovea^® for Pelvic Kinematic Measurement in Standing Position and in Sitting Position with 45° of Hip Flexion by Lucía Vicente-Pina, Rocío Sánchez-Rodríguez, Loreto Ferrández-Laliena, Jose Heredia-Jimenez, Julián Müller-Thyssen-Uriarte, Sofía Monti-Ballano, César Hidalgo-García, José Miguel Tricás-Moreno, María Orosia Lucha-López

“…Pelvic posture, anterior and posterior tilt, and total pelvic ROM in the sagittal plane were analyzed. …”
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Characteristics of strong mine pressure manifestation in composite hard roofs and determination of main controlling layers by LI Yanjun

“…The energy in the concentrated microseismic event area was reduced to 1000-2000 J, while the total microseismic energy, single-pick energy, and number of events decreased by 62.17%, 71.92%, and 56.32%, respectively, compared to the pre-splitting of the lower hard roof. …”
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Economic and Clinical Impact of Stroke and Warfarin Use for Patients with Non-valvular Atrial Fibrillation by Li Wang, Elyse Fritschel, Onur Baser

“…Warfarin prescriptions did not significantly impact total health care costs, though caution is advised to minimize hemorrhagic events.…”
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venta del prebostazgo de Bilbao durante la Guerra de Sucesión: movilización de recursos para la hacienda de Felipe V en el contexto de la construcción de un nuevo régimen (1704-170... by Rafael Guerrero Elecalde

“…Desde un enfoque de microanálisis, y a partir del análisis de este proceso, se contempla los importantes cambios que se llevaron a efecto desde la misma llegada del primer rey de la dinastía Borbón: acción de los nuevos gobernantes de la Monarquía, la implementación de las reformas políticas y el desarrollo de un programa de operaciones venales. Todo ello conllevó la renovación de elites gobernantes, con la caída de las familias poderosas tradicionales, como fueron los duques de Ciudad Real. …”
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Expansion of the known host range of Giardia duodenalis and Cryptosporidium spp. in captive wildlife at Beijing Zoo by Zhao Qianming, Pei Zhiyang, He Yongqiang, Jia Ting, Zhang Yanzhen, Zheng Mengjun, Zhang Zhenjie, Qi Meng

“…This study aimed to investigate the infection rates of these parasites in captive wildlife at Beijing Zoo. A total of 445 fecal samples were collected and analyzed using PCR. …”
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Functional and Anatomical Outcomes of Pars Plana Vitrectomy for Lamellar Macular Hole: Long-Term Follow-Up by Fabrizio Giansanti, Cristina Nicolosi, Giuseppe Ruben Barbera, Giulio Vicini, Flavia Lucarelli, Edoardo Traniello Gradassi, Vittoria Murro, Gianni Virgili, Daniela Bacherini

“…The preoperative and postoperative best-corrected visual acuity (BCVA) and spectral domain optical coherence tomography parameters were examined. Results: Preoperatively, the mean BCVA was 0.46 ± 0.22 LogMAR. …”
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Herpes Zoster after COVID-19 Infection or Vaccination: A Prospective Cohort Study in a Tertiary Dermatology Clinic by Charussri Leeyaphan, Pattriya Jirawattanadon, Sumanas Bunyaratavej, Waratchaya Panjapakkul, Thrit Hutachoke, Yanisorn Nanchaipruek, Phumithep Phumariyapong

“…This prospective cohort study involving patients diagnosed with cutaneous HZ was conducted at a dermatology clinic from October 2021 to January 2023. Results. Among a total of 232 patients with HZ, the median age was 62.0 years and 59.1% were female. …”
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EFECTOS NEUROPSICOLÓGICOS POR EL CONSUMO DE MARIHUANA EN ADULTOS JÓVENES by Edwin Pozo-Hernández, Carlos Mariño-Tamayo, Carlos Ramos-Galarza

“…Se realiza una discusión de los resultados tomando en cuenta investigaciones previas, destacando principalmente los efectos perjudiciales que el consumo de marihuana provocaría en las funciones cognitivas estudiadas, y que por lo general no son reconocidos o son minimizados por los jóvenes que consumen marihuana.…”
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Exploring Media Literacy Formation at the Intersection of Family, School, and Peers by Nika Šušterič, Katja Koren Ošljak, Veronika Tašner

“…Today, media literacy and digital skills are essential for personal communication and social interaction. …”
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