Role of the androgen receptor in melanoma aggressiveness by Marzia Di Donato, Costanza Maria Cristiani, Mariaelena Capone, Cinzia Garofalo, Gabriele Madonna, Lucia Carmela Passacatini, Margaret Ottaviano, Paolo Antonio Ascierto, Ferdinando Auricchio, Ennio Carbone, Antimo Migliaccio, Gabriella Castoria

“…At last, melanoma cells depleted of the androgen receptor become more responsive to the most commonly used immunocheckpoint inhibitors, suggesting that the receptor dampens the immunotherapy efficacy. Taken together, our findings identify the androgen receptor as a diagnostic guidance in melanoma and support the repositioning of AR blockers in clinical management of patients.…”
Get full text

Paisaje, cuerpo y residuos en Los pies de San Juan de Eduardo Lalo by Azucena Galettini

“…El paisaje urbano se construye como una “antipostal”, en la que las partes seleccionadas nunca permiten reponer un todo y en la que la propuesta de Lalo de que el sujeto “es” la ciudad establece un vínculo de fusión entre cuerpo y urbe. …”
Get full text

Global cervical cancer elimination: quantifying the status, progress, and gaps by Liangru Zhou, Yi Li, Hongyun Wang, Ruixi Qin, Zhen Han, Ruifeng Li

“…Results By 2020, four countries had achieved Target 1 (90% of girls fully vaccinated against HPV by age 15). A total of 115 countries (51 (44.35%) HICs and 64 (55.65%) LMICs)) included HPV vaccination in their national immunisation programs. …”
Get full text

Endocrine Outcome and Quality of Life After Transsphenoidal Resection of Pituitary Adenoma—A Prospective Randomized Single-Blinded Study Comparing Endoscopic Versus Microscopic Res... by Andrej Pala, Nadja Grübel, Benjamin Mayer, Ralf Becker, Fabian Sommer, Bernd Schmitz, Gwendolin Etzrodt-Walter, Christian Rainer Wirtz, Michal Hlavac

“…Arginine vasopressin deficiency was found in 2.7% (n = 1) after microscopic resection. Gross total resection was achieved in 94.4% (n = 34). No surgical complications or new neurological deficits were observed. …”
Get full text

Ensemble Classification Model With CFS-IGWO–Based Feature Selection for Cancer Detection Using Microarray Data by Pinakshi Panda, Sukant Kishoro Bisoy, Sandeep Kautish, Reyaz Ahmad, Asma Irshad, Nadeem Sarwar

“…Cancer is the top cause of death worldwide, and machine learning (ML) has made an indelible mark on the field of early cancer detection, thereby lowering the death toll. …”
Get full text

Communicating with Extension Clients about Water by Alexa J. Lamm, Phillip S. Stokes, Caroline G. Roper

“…Not only is Florida a specialty crop state, but the Florida economy also depends highly on tourism and recreation, both of which thrive on water. …”
Get full text

Firefighting with Conductive Aerosol-Assisted Vortex Rings by John LaRocco, Qudsia Tahmina, Stanley Essel, John Simonis

“…Conventional firefighting tools and methods can strain water sources, require toxic foams, or rely on pre-installed countermeasures. …”
Get full text

Enhancement of postharvest performance in Lilium tigrinum Ker Gawl flowers with Salicylic acid: a signalling molecule and a growth regulator by Moonisah Aftab, Haris Yousuf Lone, Wajahat Waseem Tantray, Aijaz A. Wani, Mohmad Arief Zargar, Inayatullah Tahir

“…Furthermore, SA treatment enhances total soluble protein content, increased proline accumulation, decreased specific protease activity and maintained lower amino acid levels. …”
Get full text

Chemical Diversity of UK-Grown Tea Explored Using Metabolomics and Machine Learning by Amanda J. Lloyd, Alina Warren-Walker, Jasen Finch, Jo Harper, Kathryn Bennet, Alison Watson, Laura Lyons, Pilar Martinez Martin, Thomas Wilson, Manfred Beckmann

“…However, a significant degree of variability was observed within four tri-clonal variants (Tocklai Variety) with TV9 exhibiting greater similarity to the Georgian N2 cultivar compared to TV8 and TV11, while TV11 was found to be most like TV1. …”
Get full text

A Case of Lenvatinib-Induced Focal Segmental Glomerulosclerosis (FSGS) in Metastatic Medullary Thyroid Cancer by Kathryn Fleming, James McGuinness, David Kipgen, Hilary Glen, Pavlina Spiliopoulou

“…Lenvatinib was a novel experimental agent at the time the treatment took place; however, its recent licensing for the treatment of thyroid malignancies in the UK makes reporting of these adverse effects all the more important now.…”
Get full text

Experimental Study on High-Cycle Fatigue Behavior of GFRP-Steel Sleeve Composite Cross Arms by Jiantao Wang, Ning Tan, Shiming Zhou, Qing Sun

“…A total of six specimens were subjected to 500 thousand cyclic loadings based on the practical engineering background. …”
Get full text

Concurrent Extraction and Analysis of Atmospheric Particulate Matter-bound PBDEs, PAHs, Nitrated PAHs, and OPEs by Hsin-Chieh Kung, Bo-Wun Huang, Chien-Er Huang, Nicholas Kiprotich Cheruiyot, Guo-Ping Chang-Chien

“…The concurrent microwave extraction took a total of 40 minutes and utilized n-hexane:acetone:dichloromethane (2:2:1 v/v). …”
Get full text

Persistent bifrontal rhinogenic contact headache by Santosh Kumar Swain, Debasmita Dubey

“…Diagnostic nasal endoscopy and computed tomography scans are important tools for the diagnosis of anatomical variations in the nasal cavity causing contact point headaches. …”
Get full text

Explainable AI-Enhanced Human Activity Recognition for Human–Robot Collaboration in Agriculture by Lefteris Benos, Dimitrios Tsaopoulos, Aristotelis C. Tagarakis, Dimitrios Kateris, Patrizia Busato, Dionysis Bochtis

“…The results highlight the central role of torso-mounted sensors, particularly in the lumbar region, cervix, and chest, in capturing core movements, while wrist sensors provided useful complementary information, especially for load-related activities. …”
Get full text

Multinational comparison of new antidepressant use in older adults: a cohort study by Robyn Tamblyn, David Westfall Bates, David L Buckeridge, Will Dixon, Alan J Forster, Nadyne Girard, Jennifer Haas, Bettina Habib, Siyana Kurteva, Jack Li, Therese Sheppard

“…Evaluation of real-world risks of TCAs is a priority for future research, given high rates of use and the potential for increased toxicity in older adults because of potent anticholinergic effects.…”
Get full text

Prise en compte de la biodiversité dans les projets d’aménagement : comment améliorer la commande des études environnementales ? by Sylvie Vanpeene-Bruhier, Pierre-André Pissard, Martin Kopf

“…Better biodiversity integration (in particular daily life nature and ecosystems functioning) strengthen impact studies requirement, compensatory measures and ecological network (Trame verte et bleue) integration into both fitting out projects and town planning documents. This requires numerous and relevant environmental datas in order to evaluate project possible impacts. …”
Get full text

LOKALUS IR GLOBALUS POŽIŪRIAI Į PRAĖJUSĮ ŠIMTMETĮ: GÜNTERIS GRASSAS VERSUS „TIME“ by Aldis Gedutis

“… Straipsnyje siekiama išnagrinėti globalios ir lokalios perspektyvos panašumus bei skirtumus. Todėl analizuojami bei lyginami G. Grasso romanas Mano šimtmetis ir kolektyvinis tekstas 80 dienų, pakeitusių pasaulį, išspausdintas amerikiečių žurnale Time. …”
Get full text

Improved Fractional Order VSS Inc-Cond MPPT Algorithm for Photovoltaic Scheme by R. Arulmurugan, N. Suthanthiravanitha

“…Nowadays a hot topic among the research community is the harnessing energy from the free sunlight which is abundant and pollution-free. …”
Get full text

Cultura arquitectónica y cultura alimentaria by Ruth Varela

“…El Mercado de Abastos de Santiago de Compostela – Praza de Abastos –, autoría del arquitecto asturiano Joaquín Vaquero Palacios (1900-1998), todavía no ha sido suficientemente estudiado, a pesar de ser una de las obras maestras de la arquitectura española del siglo XX y una infraestructura pública esencial de los sistemas alimentarios de proximidad de Compostela. …”
Get full text

窄翼缘PEC中长柱轴压整体稳定性能试验研究 by 张文轩, 石韵, 苏明周, 兰寒枫, 庄向平, 蔡仁武

Get full text