Effective gene therapy for metachromatic leukodystrophy achieved with minimal lentiviral genomic integrations by Lucas Tricoli, Sunetra Sase, Julia L. Hacker, Vi Pham, Maxwell Chappell, Laura Breda, Stephanie N. Hurwitz, Naoto Tanaka, Carlo Castruccio Castracani, Amaliris Guerra, Zhongqi Hou, Lars Schlotawa, Karthikeyan Radhakrishnan, Matthew Hogenauer, Aoife Roche, John Everett, Frederic Bushman, Peter Kurre, Rebecca Ahrens-Nicklas, Laura A. Adang, Adeline L. Vanderver, Stefano Rivella

“…In addition, our vectors achieved optimal transduction in mouse and human hematopoietic stem cells (HSCs) with minimal multiplicity of infection (MOI). Our top-performing vector (EA1) showed at least 4× more ARSA activity than the currently US and European Union (EU)-approved vector and a superior ability to secrete vesicle-associated ARSA, a critical modality to transfer functional enzymes from microglia to oligodendrocytes. …”
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Training of female health workers (FHWs) to enhance the advocacy and communication skills on COVID-19 vaccine and routine Immunization in District Peshawar Khyber Pakhtunkhwa (KP)... by Magid Al-Gunaid, Zakir Hussain, Leen Daoud, Khurram Akram

“…Additionally, training of FHWs significantly improved their knowledge and attitudes towards COVID-19 vaccination and routine EPI, contributing to the overall success of the intervention. …”
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Thoracoscopic resection of primary mediastinal liposarcoma: a case report and literature review by Yanhui Yang, Ji Li, Sipeng Cheng, Jinyuan Mei, Xin Cheng, Min Jing, Yi Wang

“…Case presentation A 38-year-old male presented to our hospital with complaints of dysphagia after meals. Chest computed tomography (CT) revealed a large space-occupying lesion in the posterior upper mediastinum, and gastroscopy identified esophageal compression without evidence of new growth. …”
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“I hate him. No, I don’t… I hate myself”: Wilkie Collins and the Anatomy of Hatred by Mariaconcetta Costantini

“…Dans ses œuvres de fiction, la haine non seulement informe la dynamique sociale interne de son époque, mais elle sert de révélateur à une curiosité portant sur des concepts psycho-ontologiques auxquels on accordera une importance toute particulière à la fin du XIXe siècle. Cet article, au travers de l’analyse des trajectoires passionnelles entre colère-haine-vengeance mises en fiction dans Basil (1852) et Armadale (1864-6), explore l’intérêt immuable que porte Collins aux sentiments antisociaux, ainsi que sa représentation complexe des expériences de désagrégation et d’exécration de soi-même qui allaient devenir des éléments centraux de la psychanalyse moderne.…”
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Mitigating overconfidence bias: A cross-sectional pilot study of male maintenance workers in the engineering sector by Luca DI GIAMPAOLO, Federica MARINO, Claudia GIURGOLA, Piergiorgio ASTOLFI, Luca COPPETA, Simone DE SIO, Paola BORRELLI, Teresa GALANTI, Laura FORCELLA, Maria Elisa MAIOLO, Kavita BATRA, Murat YILDIRIM, Hicham KHABBACHE, Amelia RIZZO, Mahmood BAHRAMIZADEH, Hiroo WADA, Qiao NIU, Hector NIETO, Francesco CHIRICO

“…Workers over 51 years old showed higher negative emotions toward safety procedures (SP) and greater intention to transgress, though actual transgressions were low. …”
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Satisfied with the worst health outcomes or unsatisfied with the best: explaining the divergence between good patient-reported outcomes and low satisfaction and vice versa among kn... by Lukas Schöner, Viktoria Steinbeck, Reinhard Busse, Carlos J. Marques

“…Abstract Objectives Total knee arthroplasty (TKA) is an effective treatment for patients with end-stage knee osteoarthritis but some patients exhibit a discrepancy between patient-reported outcomes (PROs) and patient satisfaction (PS). …”
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Enhanced understanding of hydrological connectivity among lakes on the Qiangtang Plateau by Yunmei Li, Chang Huang, Ninglian Wang, Yun Chen, Shiqiang Zhang, Hongtao Duan

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Separation of infrared and bulk in thermal QCD by The χQCD collaboration and the CLQCD collaboration, Xiao-Lan Meng, Peng Sun, Andrei Alexandru, Ivan Horváth, Keh-Fei Liu, Gen Wang, Yi-Bo Yang

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Acceso y participación de los sectores populares mexicanos en el mercado formal de crédito by Pablo Cotler, Eduardo Rodríguez-Oreggia

“…Existe un creciente interés por elaborar políticas públicas que aumentan la participación de la población de escasos recursos en los mercados crediticios formales. Tomando en consideración la diferencia que existe entre el acceso y el uso, utilizamos una base de panel de datos para examinar qué factores determinan que los sectores populares – que cuentan con acceso a servicios crediticios institucionales- hagan uso de dichos productos financieros. …”
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Photorefractive and pyroelectric photonic memory and long-term stability in thin-film lithium niobate microresonators by Xinyi Ren, Chun-Ho Lee, Kaiwen Xue, Shaoyuan Ou, Yue Yu, Zaijun Chen, Mengjie Yu

“…Our result offers insights towards understanding the fundamental noise properties and dynamic behavior of integrated TFLN material and devices.…”
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Regional development dynamics: university-business cooperation strategies by A. G. Karimli

“…In today’s world, with the globalisation process, the functions of higher education institutions have changed within the framework of new strategies and cooperation models. …”
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Estudio nacional sobre síndrome de burnout académico en residentes de urología en Colombia by Víctor I. Romero-Nieto, Wilfredo Donoso-Donoso, David A. Castañeda-Millán

“…El objetivo de este estudio es determinar la prevalencia del síndrome de burnout académico en los residentes de urología en Colombia y proponer estrategias que permitan evitar o disminuir el síndrome de burnout académico en el contexto colombiano. Método: Estudio de corte transversal, con muestreo por conveniencia en médicos residentes de urología de los diferentes programas académicos de posgrado en Colombia. …”
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Clinical performance of real-time nanopore metagenomic sequencing for rapid identification of bacterial pathogens in cerebrospinal fluid: a pilot study by Yoon Hyun Sung, Yong Kuk Ju, Hak Jun Lee, Seung Min Park, Jin Woong Suh, Jeong Yeon Kim, Jang Wook Sohn, Young Kyung Yoon

“…Nanopore-based metagenomic sequencing is expected to serve as a complementary tool for pathogen detection in CSF samples by facilitating rapid and accurate diagnosis.…”
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Honeycomb-spiderweb-inspired self-similar hybrid cellular structures for impact applications by K. Tewari, M.K. Pandit, M.M. Mahapatra, P.R. Budarapu

“…The energy absorption is enhanced by optimizing the geometry and topology for a given mass. The proposed hybrid cellular structure is arrived after a thorough analysis of topologically enhanced self-similar structures. …”
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Study of drilling muds on the anti-erosion property of a fluidic amplifier in directional drilling by Jiang-fu He, Peng-yu Zhang, Qi-lei Yin, Kun Yin, Hou-ping Liu

“…Due to some drawbacks of conventional drilling methods and drilling tools, the application of hydraulic hammers with a fluidic amplifier have been extensively popularized since its emergence in recent years. …”
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Personalized treatment strategies for breast adenoid cystic carcinoma: A machine learning approach by Sakhr Alshwayyat, Mahmoud Bashar Abu Al Hawa, Mustafa Alshwayyat, Tala Abdulsalam Alshwayyat, Siya sawan, Ghaith Heilat, Hanan M. Hammouri, Sara Mheid, Batool Al Shweiat, Hamdah Hanifa

“…This study was designed to assess the efficacy of various treatment approaches for BACC and to create the first web-based tool to facilitate personalized treatment decisions. …”
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Detection and Quantification of the Relationship between the Ratio of Triglycerides over High-Density Lipoprotein Cholesterol and the Level of Serum Uric Acid: One Cross-Sectional... by Yuexi Li, Yuhan Luo, Qiaoli Wang, Xiaoqin Liu

“…Hence, the aim of this research was to determine this association. Methods. A total of 5,402 participants who underwent physical examinations in 2021 were analyzed during our cross-sectional research. …”
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Ayasofya 23: Süleymaniye Kütüphanesinde Bulunan Abbâsî Dönemi Bir Kur’ân-ı Kerîm Elyazması by Tuba Karaşahin, Esra Gözeler

“…Ancak yazmanın menşei halen belirsizdir. Topkapı E.H. 26 envanter numaralı mushaf varaklarının Topkapı Sarayı Kütüphanesine nereden intikal ettiği bilgisi mevcut olmamakla birlikte yalnızca bu varaklar üzerinde iki padişah mührü mevcuttur. …”
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Land Use Effects on Soil Quality Indicators: A Case Study of Abo-Wonsho Southern Ethiopia by Awdenegest Moges, Melku Dagnachew, Fantaw Yimer

“…This study compared soil quality within culturally protected forest areas and adjacent grassland, grazing land, and farmland in Abo-Wonsho, Southern Ethiopia. A total of 40 soil samples (4 land uses × 5 replications × 2 soil depth layers: 0 to 10 cm and 10 to 20 cm) were collected for analysis. …”
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Emigracja z Galicji oczyma maturzystów A.D. 2022 by Joanna Wojdon

“…Z przeprowadzonej analizy wynika, że wiedza polskiej młodzieży na temat emigracji “za chlebem” jest raczej powierzchowna i ukształtowana nie tylko w toku formalnej edukacji historycznej. Również sprawne posługiwanie się myśleniem przyczynowo-skutkowym oraz traktowanie emigracji jako niebudzącego emocji sposobu poprawy warunków życia można przypisać wpływom czynników pozaszkolnych, na których można jednak budować proces dydaktyczny.…”
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