Tumor mutational burden quantification from targeted gene panels: major advancements and challenges by Sara Gandini, Laura Fancello, Pier Giuseppe Pelicci, Luca Mazzarella

“…Tumor mutational burden (TMB), the total number of somatic coding mutations in a tumor, is emerging as a promising biomarker for immunotherapy response in cancer patients. …”
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Assessment of knowledge, attitude and practice (KAP) on oral health among secondary-level students: a cross-sectional study in Kathmandu, Nepal by Nishika Aryal, Anuja Rajbhandari

“…While most students demonstrated good OH knowledge (77.2%) and positive attitudes (91.9%), there was reluctance towards dental visit. Additionally, only 41% practised adequate OH, with issues like suboptimal brushing technique, low floss use and high consumption of chocolates. …”
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Objectivation négociée et gestion contestée de l’environnement by Thomas Debril, Gaël Plumecocq, Olivier Petit

“…The use of particular concepts to understand natural resources, or particular tools to manage them relates to qualification processes, which reveals a wide range of human-nature relationships. …”
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Alteration, mineralization, geochemistry and fluid inclusion investigations in Joftrud prospect area, southwest of Birjand by Omid Shareipour, Azadeh Malekzadeh Shafaroudi, Maryam Javidi Moghaddam

“…Materials and methods In the field work, a total of 80 samples were taken mainly from igneous units and ores. 40 thin sections and polished slabs were examined by an optical microscope. …”
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Agrolandscapes and their role in ensuring environmental safety by Larysa Piskunova, Tetiana Zubok, Alla Klepko, Kateryna Кarabach, Alina Kudryavytska

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Dual Regulation of Ionic Effect on <i>Zostera marina</i> L. Seed Germination and Leaf Differentiation in Low-Salinity Conditions by Peilong Li, Yaping Gao, Zengjie Jiang, Linjie Wang, Xiaoli Sun, Jiaqi Wang, Jing Wang, Haidong Sui, Junwei Wang, Yitao Zhang

“…Antioxidant enzyme activities were activated under low-salinity conditions, which supported germination within a tolerable oxidative stress range.…”
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First-line treatment for advanced or metastatic EGFR mutation-positive non-squamous non-small cell lung cancer: a network meta-analysis by Mengyao Zhang, Lan Sun

“…Stata 15.0 and R 4.3.2 software were utilized for the network meta-analysis.ResultsA total of 30 RCTs, comprising 8654 participants, were included. …”
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Progression of Diabetic Retinopathy and Declining Renal Function in Patients with Type 2 Diabetes by AJin Cho, Hayne Cho Park, Young-Ki Lee, Young Joo Shin, So Hyun Bae, Hakyoung Kim

“…Methods. We included a total of 1527 patients with type 2 diabetes who followed up in our diabetes clinic and underwent fundus photographic examinations from August 2006 to February 2014. …”
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The Cultural District Between Planning and Spontaneity: The Agglomeration Dynamics in Manifattura delle Arti in Bologna by Liola Urso, Valeria Morea

“…Policymakers attempted to recreate this phenomenon through top-down strategies. However, it has been observed that clusters often arise naturally without direct intervention from local governments or policy incentives. …”
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Two-Degree Vibration Analysis of a Horizontal Axis Turbine Blade by Finite Differential Methods by Youfeng Zhu, Hongyu Zang, Xiaofei Kong, Peng Ban

“…The blade tip vibration in autonomous and nonautonomous system can be simulated by MATLAB vibration toolboxes in time domain. The convergent, flutter, and divergent vibration curves were plotted in the directions of lead-lag and flapping.…”
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A Critique on the Methods of Teaching Verbs of Motio in Russian Language in Iranian Universities by Rezvan Hasanzadeh

“…Learners should know from the beginning that the language they are about to learn, especially at the beginning, will be slightly different from the languages of the languages in which it is considered their mother tongue. Therefore, in the present article, based on the teaching of motion verbs in the Russian language and the many problems that language learners have in the practical and applied learning of this language category, qualitative solutions to the teaching of motion verbs are proposed. …”
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How Does Social Mobilization Shape the Collective Coproduction of Urban Community Regeneration in China? by Jinpeng Wu, Yuting Chen, Ruiqi Shi, Jing Xiong

“…Against the backdrop of Chinese grassroots governance, this article employs social mobilization theory to explore the key factors contributing to collective coproduction and develops a theoretical framework that focuses on how the combination of top-down and bottom-up social mobilization shapes it. …”
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Renal Parenchyma Perforation and Hematoma Formation following Double-J Stent Insertion in a Solitary Functioning Kidney: An Unusual Complication by Michael S. Nomikos, Zacharias Chousianitis, Christos Georgiou, Chrysostomos Georgellis, Panagiotis Rikas, Theodoros Anagnostou

“…Follow-up noncontrast computed tomography (CT) of the abdomen was performed the first and third months after stent placement which showed stabilization of the hematoma.…”
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Ocular Surface Disorders in Intensive Care Unit Patients by Tuba Berra Saritas, Banu Bozkurt, Baris Simsek, Zeynep Cakmak, Mehmet Ozdemir, Alper Yosunkaya

“…Keratitis was observed in 4 patients (10%) who were treated successfully with topical antibiotics. Mean Schirmers test results were 7.6 ± 5.7 mm/5 min (median 6.5 mm/5 min) in the right, and 7.9 ± 6.3 mm/5 min (median 7 mm/5 min) in the left eyes. …”
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The Mediating Effect of Religiosity in Evaluating Individual Cultural Values Regarding Interest by Selim Aren, Hatice Nayman Hamamcı

“…In this context, data were collected between May 14 and June 1, 2020, in Turkey, a country where the majority of individuals are Muslim but Western values and synthesis of Eastern and Western cultures have been adopted. A total of 1.934 people participated in the survey. …”
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Wybrane aspekty zielonego budownictwa w Polsce w kontekście systemów certyfikacji budynków ekologicznych by Aleksandra Lewandowska, Krzysztof Rogatka, Mirosław Wylon

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Decision-Making on the Solution of a Stochastic Nonlinear Dynamical System of Kannan-Type in New Sequence Space of Soft Functions by Meshayil M. Alsolmi, Awad A. Bakery

“…The idealization of the mappings has been achieved through the use of extended s-soft functions and this sequence space of soft functions. This new space’s topological and geometric properties, the multiplication mappings that stand in on it, and the mappings’ ideal that correspond to them are discussed. …”
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Absence of Flexor Carpi Radialis during an Elective Carpometacarpal Arthroplasty of the Thumb: A Rare Anatomical Variation by Stratos S. Sofos, Muhammad Riaz

“…This rare anatomical variation posed a clinical dilemma to us and we highlight the importance of the surgeon being aware of this anatomical variation of an important structure both as a reconstruction tool and as an anatomical landmark. Methods. This anatomical variation of the unilaterally absent FCR was found upon dissection during a carpometacarpal arthroplasty of the thumb. …”
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Souffrance au travail et enjeux de santé : le rôle charnière de l’inflammation et du stress oxydant by Philippe Davezies

“…The information needed to examine the question is scattered across different scientific fields and has only partially been brought together. Nevertheless, the present inquiry emphasizes the echoes and hypothetical or proved links between phenomena such as the emotional repression described by occupational psychopathology, the notion of alexithymia in the field of psychosomatics, the disturbance of cortisol activity and secretion in chronic stress contexts, and the role of inflammation in the genesis of stress-related disorders. …”
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The effects of citral on the intestinal health and growth performance of American bullfrogs (Aquarana catesbeiana) by Xiaoting Zheng, Qiuyu Chen, Xueying Liang, Jingyi Xie, Alfredo Loor, Hongbiao Dong, Jinlong Yang, Jiasong Zhang

“…Antioxidant markers, including total antioxidant capacity (T-AOC) and glutathione (GSH), were highest at 2 mL/kg, while higher citral concentrations reduced superoxide dismutase (SOD) and catalase (CAT) activities, indicating potential oxidative stress at 8–16 mL/kg (P < 0.05). …”
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