Physicians’ Perceptions of the Quality of Palliative Care and of the Importance of Collaboration in Interdisciplinary Teams in Norwegian Nursing Homes by Skomakerstuen Ødbehr L, Hov R, Sanaker H, Sandsdalen T

“…Interviews were conducted between February 2023 to May 2023, analyzed using qualitative content analysis.Results: Three themes describe the content of the findings: i) Comprehensive care plans enhance the quality of palliative care, ii) A collaborative team provides higher-quality care than the sum of its parts, iii) Systemic and environmental factors affect the ability to ensure continuity of care.Conclusion: The physicians in this study expressed that the quality of palliative care in nursing homes depended on comprehensive care plans, including up-to-date knowledge of medical treatment options, partnership with the patient and relatives, and a consistent holistic approach to the patient. …”
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Multigenerational family coaggregation study of obsessive-compulsive disorder and cardiometabolic disorders by David Mataix-Cols, Christian Rück, Lorena Fernández de la Cruz, Kayoko Isomura, Henrik Larsson, Paul Lichtenstein, Brian M D’Onofrio, Anna Sidorchuk, Zheng Chang, James J Crowley, Ralf Kuja-Halkola, Isabell Brikell, Josep Pol-Fuster, Anna Holmberg, Lina Martinsson

“…This population-based family study explored the familial co-aggregation of OCD and cardiometabolic disorders.Methods We identified 6 049 717 individuals born in Sweden between 1950 and 2008, including 50 212 individuals with OCD, and followed them up to 2020. These individuals were linked to their mothers, fathers, full siblings, maternal and paternal half siblings, aunts, uncles and cousins. …”
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Adapting first aid education to fragile contexts: A qualitative study

“…We interviewed educators, from six countries where conflict, geography or resources deemed them to be fragile, to explore which educational approaches were used and found effective in educating potential lay responders. …”
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Genome-wide transcriptome analysis and drug target discovery reveal key genes and pathways in thyroid cancer metastasis by Minjing Zou, Amal Qattan, Monther Al-Alwan, Hazem Ghebeh, Naif Binjumah, Latifa Al-Haj, Khalid S. A. Khabar, Abdulmohsen Altaweel, Falah Almohanna, Abdullah M. Assiri, Abdelilah Aboussekhra, Ali S. Alzahrani, Ali S. Alzahrani, Yufei Shi

“…Braf-mutant Met cells developed resistance to BRAFV600E inhibitor PLX4720, but remained sensitive to β-catenin inhibitor PKF118-310.ConclusionWe have identified several overexpressed genes/pathways in thyroid cancer metastasis, making them attractive therapeutic targets. Given the complexity of metastasis involving multiple pathways (PD-L1, Mertk, IL6, COX-1/Tbxas1-TXA2), simultaneously targeting more than one of these pathways may be warranted to achieve better therapeutic effect for metastatic thyroid cancer.…”
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SUMO-Specific Peptidase 5 Promotes Oesophageal Squamous Cell Carcinoma Growth through the NF-κB-SLC1A3 Axis by Chaoxiang Du, Yunfan Hu, Xinyu Yang, Zhe Zhang, Jianmin Gu, Tao Zhang, Renfeng Wang, Shaoyuan Zhang, Lijie Tan, Guiping Yu

“…Background: This study investigates the role of small ubiquitin-like modifier (SUMO)-specific peptidase 5 (SENP5), a key regulator of SUMOylation, in esophageal squamous cell carcinoma (ESCC), a lethal disease, and its underlying molecular mechanisms. …”
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Sewage sludge-based organomineral fertilizer: A pathway to enhanced soil fertility and chickpea production by Athos Rodrigues Soares Viana, Rodinei Facco Pegoraro, Regynaldo Arruda Sampaio, Luiz Arnaldo Fernandes, Leidivan Almeida Frazão, Cândido Alves da Costa, Verônica Aparecida Santos Ferreira Soares

“… Purpose: Sewage sludge compounds possess physical and chemical attributes that make them well-suited for formulating fertilizers intended for agricultural purposes. …”
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Upcycling supercritical-CO2-defatted tiger nut milk Co-products into pork burgers: A sustainable fat replacer with enhanced quality properties by Raquel Lucas-González, Carmen Botella-Martínez, Manuel Salgado-Ramos, Noelia Pallarés, Pedro V. Martínez-Culebras, Francisco J. Barba, Juana Fernández-López

“…Although the presence of the defatted tiger nut co-products reduced the scores for most of the sensory attributes, when added up to 3 %, all of them were rated higher than 5. …”
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The performance of upper arm circumference for age in diagnosing severe acute malnutrition in children aged 6 to 59 months in South Kivu, Eastern Democratic Republic of Congo: Lwir... by Gaylord Ngaboyeka, Armand Mulume, Emmanuel Lurhangire, Anouk Neven, Lydia Zigabe, Serge Balolebwami, Pacifique Mwene-Batu, Michelle Dramaix, Philippe Donnen, Ghislain Bisimwa

“…Of all cases of SAM (identified by at least one of the WHZ, MUAC, or MUACZ indicators), MUACZ alone identified 85% of them, surpassing other criteria such as MUAC (58%) and WHZ (45%). …”
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Cancer phylogenetic tree inference at scale from 1000s of single cell genomes by Salehi, Sohrab, Dorri, Fatemeh, Chern, Kevin, Kabeer, Farhia, Rusk, Nicole, Funnell, Tyler, Williams, Marc J., Lai, Daniel, Andronescu, Mirela, Campbell, Kieran R., McPherson, Andrew, Aparicio, Samuel, Roth, Andrew, Shah, Sohrab P., Bouchard-Côté, Alexandre

“…Phylogenetic reconstruction is central to identifying sub-populations and distinguishing the mutational processes that gave rise to them. Existing phylogenetic tree building models do not scale to the tens of thousands of high resolution genomes achievable with current scWGS methods. …”
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The Role of Human Agency in Global Urban Health by Kai Michael Gensitz, Catherine Woods, Tadhg MacIntyre, Claudio R. Nigg

“…Methods Conceptualization was done through iterative literature reviews, including citation tracking of key papers, which informed a Delphy study to reach consensus with the expert consortium of the EU-Horizon project “GoGreenNext” on key socio-ecological components (SECs). …”
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Bringing MDMA-assisted therapy for PTSD to traditional healthcare systems: tending to set and setting by Dimitri Perivoliotis, Dimitri Perivoliotis, Kayla Knopp, Kayla Knopp, Shannon Remick, Allie Kaigle, Allie Kaigle, Christopher S. Stauffer, Christopher S. Stauffer, Chandra Khalifian, Chandra Khalifian, Tamara R. Wachsman, Bettye E. Chargin, Andrew W. Bismark, Andrew W. Bismark, Al Alam, Al Alam, Leslie Morland, Leslie Morland, Leslie Morland

“…Although effective evidence-based trauma-focused psychotherapies for posttraumatic stress disorder (PTSD) are available, a significant proportion of patients show a suboptimal response or do not complete them. MDMA-assisted therapy (MDMA-AT) for PTSD is a promising intervention currently being evaluated in numerous studies worldwide, including investigation for potential Food and Drug Administration (FDA) approval in the United States. …”
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Pengaruh Valsartan Terhadap Fibrosis Ginjal pada Obstruksi Ureter by Alvarino .

“…Only rats survive<br />until at least 7th day are included in the study. ResultFrom thirteen wistar rats in no treatment group, two of them<br />having moderate interstitial fibrosis and eleven with mild interstitial fibrosis while all rats in valsartan group had mild<br />interstitial fibrosis (p &gt; 0.05). …”
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Identifying barriers and potential solutions to improve equitable access to community eye services: an exploratory sequential mixed methods study protocol by Min Kim, David Macleod, Michael Gichangi, Andrew Bastawrous, Matthew J Burton, Jacqueline Ramke, Oathokwa Nkomazana, Sailesh Mishra, Shalinder Sabherwal, Luke Nelson Allen, Abhishek Roshan, Sarah Karanja, Ari Ho-Foster, Keneilwe Motlhatlhedi, Nigel Bolster, Mohd Javed, Malebogo Tlhajoane, Bakgaki Ratshaa, John Tlhakanelo

“…Introduction Access to care varies by sociodemographic group, with some groups facing higher barriers to care than others. This study will use novel methods to explore barriers and potential solutions as perceived by members of the population groups who are least able to access care. …”
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Development of a Recombinant Fusion Vaccine Candidate Against Lethal <i>Clostridium botulinum</i> Neurotoxin Types A and B by Eun-Sun Choi, Seong-Wook Pyo, So-Hyeon Kim, Jun-Ho Jeon, Gi-Eun Rhie, Mi-Ran Yun, Hwajung Yi, Yoon-Seok Chung

“…Results: The antibody titer in mice immunized with rHC_CB-L-HC_CA was significantly higher than that in mice immunized with alum alone, protecting them from the lethal challenges of BoNT/A (10⁵ 50% lethal dose, LD₅₀) and B (10³ LD₅₀). …”
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Process Evaluations of Interventions for the Prevention of Type 2 Diabetes in Women With Gestational Diabetes Mellitus: Systematic Review by Iklil Iman Mohd Sa'id, Natasha Hotung, Madeleine Benton, Iliatha Papachristou Nadal, Anisah Baharom, Matthew Prina, Barakatun Nisak Mohd Yusof, Kimberley Goldsmith, Samantha Birts, Ching Siew Mooi, Angus Forbes, Khalida Ismail, Boon How Chew

“…The Medical Research Council’s PE framework of complex interventions was used to identify key PE components. The Mixed Method Appraisal Tool was used to assess the quality of included studies. …”
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Contribution à l’étude de la mobilité de l’hallux et de la phylogénie des primates actuels by J Norbert Kuhlmann

“…Also, 436 foot skeletons of primates have been measured and the measurements converted to a percentage relative to the length of the 3rd metacarpal, in order to compare them, despite their difference in size (collections of the Museum d’Histoire Naturelle of Paris)Results: The hallux column is always very developed and often twice longer than that of the pollex. …”
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Preconditioning by Hydrogen Peroxide Enhances Multiple Properties of Human Decidua Basalis Mesenchymal Stem/Multipotent Stromal Cells by T. Khatlani, D. Algudiri, R. Alenzi, A. M. Al Subayyil, F. M. Abomaray, E. Bahattab, A. S. AlAskar, B. Kalionis, M. F. El-Muzaini, M. H. Abumaree

“…We previously reported that MSCs from the decidua basalis (DBMSCs) of human placenta have many important cellular functions that make them potentially useful for cell-based therapies. …”
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Targeted reproductive management for lactating Holstein cows: Economic return by Ricardo C. Chebel, Tomas Gonzalez, Ana B. Montevecchio, Klibs N. Galvão, Albert de Vries, Rafael S. Bisinotto

“…The gross profit [(milk income + sale value + subsequent lactation calf value) − (feed cost + replacement cost + fixed cost + reproductive management cost)] of cows in the TRM treatment was $108 greater than the control treatment ($3,061.6 ± $45.9 vs. $2,953.8 ± $45.2). …”
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Identifying the Antecedents of Employee Perceptions of Human Resource Practices Using Signaling Theory by Aryan Gholipour, Mohammad Abooyee Ardakan, Neda Mohammad Esmaeili, Atiyeh Rasouli

“…In other words, organizations design and implement HR systems and processes that aim to achieve these goals and desired outcomes. …”
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3D-QSAR, design, molecular docking and dynamics simulation studies of novel 6-hydroxybenzothiazole-2-carboxamides as potentially potent and selective monoamine oxidase B inhibitors by Dong Xie, Dong Xie, Yongzheng Tian, Li Cao, Penghang Guo, Penghang Guo, Zhibiao Cai, Jie Zhou

“…The ten most promising compounds were screened based on the IC50 values and tested for molecular docking. …”
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