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1961
A truncated pre-F protein mRNA vaccine elicits an enhanced immune response and protection against respiratory syncytial virus
Published 2025-02-01“…Our findings suggest that LC2DM-LNP could serve as an alternative RSV vaccine candidate for high-risk groups.…”
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1962
Predicting cardiovascular outcomes in Chinese patients with type 2 diabetes by combining risk factor trajectories and machine learning algorithm: a cohort study
Published 2025-02-01“…Risk stratification improvements were assessed through net reclassification improvement (NRI) and integrated discrimination improvement (IDI). …”
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1963
Tradition and Development of Lithuanian Terminology
Published 2024-03-01“…It is during this period that textbooks and systematic dictionaries were produced in various fields of science (mathematics, geometry, zoology, engineering, philosophy, law, etc.). …”
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1964
Designing a Stock Recommender System Using the Collaborative Filtering Algorithm for the Tehran Stock Exchange
Published 2024-06-01“…Following, buy and sell signals were generated using the stock-based collaborative filtering algorithm during the same period. …”
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1965
Exploratory study on the ascending pain pathway in patients with chronic neck and shoulder pain based on combined brain and spinal cord diffusion tensor imaging
Published 2025-02-01“…ObjectiveTo explore the changes in the white matter microstructure of the ascending pain conduction pathways in patients with chronic neck and shoulder pain (CNSP) using combined brain and spinal cord diffusion tensor imaging techniques, and to assess its correlation with clinical indicators and cognitive functions.Materials and methodsA 3.0T MRI scanner was used to perform combined brain and spinal cord diffusion tensor imaging scans on 31 CNSP patients and 24 healthy controls (HCs), extracting the spinothalamic tract (STT) and quantitatively analyzing the fractional anisotropy (FA) and mean diffusivity (MD) which reflect the microstructural integrity of nerve fibers. Additionally, these differences were subjected to partial correlation analysis in relation to Visual Analog Scale (VAS) scores, duration of pain, Self-Rating Anxiety Scale (SAS), and Self-Rating Depression Scale (SDS).ResultsCompared to HCs, CNSP patients showed decreased mean FA values and increased mean MD values in bilateral intracranial STT compared to the HC group, but two-sample t-test results indicated no statistically significant differences (p > 0.05). …”
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1966
Nomograms for predicting recurrence of HER2‐positive breast cancer with different HR status based on ultrasound and clinicopathological characteristics
Published 2024-09-01“…Eighty percent of the original samples from HR−/HER2+ and HR+/HER2+ patients were extracted by bootstrap sampling as the training cohorts, while the remaining 20% were used as the external validation cohorts. …”
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1967
Relationship between albumin-corrected anion gap and lumbar spine bone mineral density: a cross-sectional study
Published 2025-02-01“…Demographic and clinical characteristics were analyzed, including age, sex, education level, body mass index (BMI), and prevalence of diabetes and hypertension. …”
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1968
Exploring the functional role of POU5F1 using CRISPR RNP electroporation of zygote (CRISPR-EZ) in buffaloes
Published 2023-11-01“…We developed an easy and straightforward protocol for gene editing, which could serve as a valuable method for studying the functional genomics of the buffalo embryos. …”
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1969
E3 ubiquitin ligase SYVN1 as a promising therapeutic target for diverse human diseases
Published 2025-02-01“…Numerous studies conducted in recent years indicate that mammalian E3 ubiquitin ligases serve as key regulators in the maintenance of cellular homeostasis by targeting the ubiquitination of substrate proteins and activating downstream signaling pathways. …”
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1970
Inpatient preferences among patients with multiple chronic conditions in China: A discrete choice experiment
Published 2025-02-01“…A partial factor analysis was performed to generate selection sets. Data were collected from MCC patients aged between 35 and 75 years, in Fuqing City, China. …”
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1971
Examining the Impact of Cognitive and Emotional Factors on Consumer Behavioral Responses in Online Behavioral Advertising
Published 2024-03-01“…Descriptive statistics were conducted using SPSS 26, while Smart PLS3 software was employed for inferential statistics. …”
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1972
Assessment of point-of-care quantitative serum canine pancreatic lipase testing for diagnosing acute pancreatitis in dogs
Published 2025-02-01“…Serum Vcheck CPL and SNAP ® cPL were tested, and clinical consensus scores were determined by 5 internists. …”
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1973
The Impact of Online Interactive Platform Services on Oral Health Behaviors in Older Adults With Mild Cognitive Impairment: Protocol for a Randomized Controlled Trial
Published 2025-02-01“…If its effectiveness is validated and e-COM(OH) is deemed acceptable, appropriate, and feasible, it could serve as a strategic approach to address oral health issues and prevent cognitive decline in older adults with mild cognitive impairment.Trial Registration: The trial has been registered on the www.chictr.org.cn registration platform on 19 April 2024 (registration number: ChiCTR2400083250).Keywords: aged, cognitive dysfunction, internet, oral hygiene, randomized controlled trial…”
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1974
An intelligent lithology identification method for sandstone and mudstone strata and its applications: A case study of the Jurassic strata in the Lunnan area, Xinjiang, China
Published 2025-01-01“…Besides, these results can serve as a valuable reference for research on methods for fine-scale identification of complex lithologies.…”
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1975
Altered functional network topology properties to detect anxiety and depression caused by Crohn’s disease and disease severity
Published 2025-02-01“…Conclusion: Both global and regional topologies of brain networks were impaired in individuals with CD, which were correlated with clinical scores, suggesting that these values could serve as neuroimaging metrics reflecting the degree of anxiety caused by CD and CD severity.…”
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1976
Yiqi Juanshen decoction alleviates renal interstitial fibrosis by targeting the LOXL2/PI3K/AKT pathway to suppress EMT and inflammation
Published 2025-02-01“…These findings suggest that YQJSD may serve as a promising therapeutic management of RIF in CKD patients.…”
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1977
Investigating the response mechanisms of the intertidal seagrass Zostera japonica to increased UVB radiation through physiological, transcriptomic, and metabolomic analyses
Published 2025-02-01“…To mitigate these adverse effects, the expression levels of genes related to antioxidants and UV-absorbing compounds, including flavonoids (PAL, 4CL, CHS, CHI, F3H) and antioxidant enzymes (DHAR, MDHAR, APX), were upregulated. The increased synthesis of these compounds serves to scavenge accumulated ROS and absorb UV radiation. …”
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1978
Transcranial vibration stimulation at 40 Hz induced neural activity and promoted the coupling of global brain activity and cerebrospinal fluid flow
Published 2025-03-01“…Results: Significant increases were observed in both ALFF and fALFF metrics, indicating that 40 Hz TVS effectively enhanced spontaneous brain activity. …”
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1979
Evaluation of the Back-in-Action test Battery In Uninjured High School American Football Players
Published 2023-06-01“…CMJ height and Quick-Feet results were not statistically different (p>0.05), Parkour-Jump times (AF: 8.18/ 8.13 sec.; RP: 5.9/5.9sec.; p<0.001) were significantly slower. …”
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1980
RETRACTED ARTICLE: A prospective diagnostic model for breast cancer utilizing machine learning to examine the molecular immune infiltrate in HSPB6
Published 2024-10-01“…Conclusion Our findings have identified compelling molecular targets and distinctive diagnostic markers for the clinical management of breast cancer. This data will serve as crucial guidance for further research in the field.…”
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