The protein circPETH-147aa regulates metabolic reprogramming in hepatocellular carcinoma cells to remodel immunosuppressive microenvironment by Tian Lan, Fengwei Gao, Yunshi Cai, Yinghao Lv, Jiang Zhu, Hu Liu, Sinan Xie, Haifeng Wan, Haorong He, Kunlin Xie, Chang Liu, Hong Wu

“…Here we show that Norathyriol is a promising anti-HCC agent that contributes to attenuating the resistance of advanced HCC to immune checkpoint blocker (ICB) therapies.…”
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Die uitbeelding van die vroulike rol in advertensies in Suid-Afrikaanse vrouelydskrifte by Angela Petersen

“…Up to now no studies have been undertaken in support or otherwise of this concern. However, theories of mass communications support the fact that advertising is powerful enough to prescribe and reflect the existing values and norms of the society. …”
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Melissopalynological and Volatile Compounds Analysis of Buckwheat Honey from Different Geographical Origins and Their Role in Botanical Determination by Sara Panseri, Alessandra Manzo, Luca Maria Chiesa, Annamaria Giorgi

“…The results showed that buckwheat honey samples that contained, to different extents, buckwheat pollen grains on melissopalynological analyses showed similar VOCs profiles, distinguishing them from the other honey floral types analyzed. …”
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Mathematical model of a three-phase-multiphase transformer phases converter with a series connection of coils of each phase of secondary winding by Yu. V. Moskalev

“…Using a mathematical model, the operating characteristics are calculated and constructed. The results of theoretical calculations and experimental measurements are compared. …”
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Research of high strength steels bending by V. A. Tаmila, M. L. Nesterovich

“…To check the effect of the welding process on the steel under study, the hardness of the weld and the zone of thermal influence were measured. The weld was checked by X-ray television control for defects in the weld joint.To analyze the possibility of free bending with local heating experiments on tempering samples were conducted in order to identify its optimum temperature at which no cracking occurs in the steels after bending. …”
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Radiative Mixed Convection over an Isothermal Cone Embedded in a Porous Medium with Variable Permeability by M. F. El-Amin, N. A. Ebrahiem, Amgad Salama, Shuyu Sun

“…The interaction of mixed convection with thermal radiation of an optical dense viscous fluid adjacent to an isothermal cone imbedded in a porous medium with Rosseland diffusion approximation incorporating the variation of permeability and thermal conductivity is numerically investigated. …”
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Socio-Economic Challenges for the Urban Ecosystem: Complex Model of Smart Tourism and Infrastructure by Gevorg Orbelyan

“…Through this framework, the study offers a blueprint for advancing Yerevan’s digital transformation in ways that align with global smart city trends, thereby promoting sustainable economic growth, social inclusivity, and environmental stewardship. …”
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Alzheimer’s disease pathogenesis and risk factors by A. Gerulytė, L. Strumylaitė

“… The article reviews the main hypothesis explaining the pathogenesis of Alzheimer’s disease in the formation and accumulation of P-amyloid plaques and neurofibrillary plexus in the brain as well as related theories on the mechanisms of copper and zinc dysregulation, excitotoxicity, cholinergic system dysfunction, and autophagy disorders. …”
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A Novel Version of HPM Coupled with the PSEM Method for Solving the Blasius Problem by Uriel Filobello-Nino, Hector Vazquez-Leal, Jesus Huerta-Chua, Victor Manuel Jimenez-Fernandez, Mario Alberto Sandoval-Hernandez, Enrique Delgado-Alvarado, Victor Manuel Tlapa-Carrera

“…In the same way, PHPM will propose an adequate initial trial function provided of some unknown parameters in such a way that it will not evaluate the initial conditions in the iterations of the process; therefore, this set of parameters will be employed with the purpose of adjusting in the best accurate way the proposed approximation at the final part of the process. …”
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The Impact of AI-Enhanced Digital Marketing Strategies on Consumers’ Purchase Intention for Lifestyle Products by Ali Ghufran, Waqar Ahmad

“…The study contributes to the theory by highlighting CM as a critical mediator linking CA s to PB for lifestyle products, advancing understanding of the attitude-behavior relationship in consumer behavior models. …”
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Designing of an innovative conserved multiepitope subunit vaccine targeting SARS-CoV-2 glycoprotein and nucleoprotein through immunoinformatic by Temitope Isaac Adelusi, Abdeen Tunde Ogunlana, Moyosoluwa Precious Oyewole, Taiwo Ooreoluwa Ojo, Olamide Tosin Olaoba, Elijah Kolawole Oladipo, Shopnil Akash, Samir Ibenmoussa, Mohammed Bourhia, Yousef A. Bin Jardan, Baye Sitotaw

“…While the nucleoprotein (N) in the ribonucleoprotein core binds to the viral RNA genome. Therefore, our objective is to develop a novel vaccine candidate targeting the dominant T-cell and B-cell epitopes of the immune system. …”
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Modulatory Effect of 1,25-Dihydroxyvitamin D3 on IL1β-Induced RANKL, OPG, TNFα, and IL-6 Expression in Human Rheumatoid Synoviocyte MH7A by Xiaoke Feng, Chengyin Lv, Fang Wang, Ke Gan, Miaojia Zhang, Wenfeng Tan

“…Considering that 1,25(OH)2D3 has been suggested as a potent inducer of RANKL expression, it should clarify whether vitamin D supplement could result in RANKL overexpression and thereby facilitate excessive osteoclastogenesis and bone resorption in RA. …”
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Monitoring of Large Raptors Using a Smart System in the South of Kostanay Region, Kazakhstan by Alexey Yu. Timoshenko, Alexander V. Putilin, Radik R. Salemgareev, Georgy Yu. Timoshenko, Kanat Batyrkhanuly

“…There are many effective tools for collecting data on wildlife in world practive, and the SMART system is one of them. It allows us to gather and analyze information. …”
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Amyloids in bladder cancer hijack cancer-related proteins and are positive correlated to tumor stage by Diego Alem, César X. García-Laviña, Francisco Garagorry, Dardo Centurión, Joaquina Farias, Hany Pazos-Espinosa, María Noel Cuitiño-Mendiberry, Carolina Villadóniga, Susana Castro-Sowinski, Martín Fló, Federico Carrión, Brenda Iglesias, Kevin Madauss, Lucía Canclini

“…It is proposed that amyloids function as structures that sequester key proteins. Therefore, amyloids should be considered in the study and diagnosis of bladder cancer.…”
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Synthesis and kinetic evaluation of analogs of (E)-4-amino-3-methylbut-2-en-1-yl diphosphate, a potent inhibitor of the IspH metalloenzyme by Petit, Benoît Eric, Jobelius, Hannah, Bianchino, Gabriella Ines, Guérin, Mélina, Borel, Franck, Chaignon, Philippe, Seemann, Myriam

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Exploring Employee Perspectives on Workplace Technology: Usage, Roles, and Implications for Satisfaction and Performance by Andreea Barbu, Mirona Ana Maria Ichimov, Iustina Cristina Costea-Marcu, Gheorghe Militaru, Dana Corina Deselnicu, Georgiana Moiceanu

“…Also, the research results address the support of personal and professional development and emphasize the importance of balance between personal and professional life through workplace flexibility—an aspect relatively unexplored in the specialized literature. Apart from the theoretical contributions that the study offers for the development of the literature, the results of this research offer a practical perspective for companies in the field of engineering, suggesting future research directions and recommendations for optimizing performance and increasing the level of employee satisfaction through the implementation of appropriate and personalized digital solutions.…”
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Surfacing of Latent Time Memories Supports the Representational Basis of Timing Behavior in Mice by Tutku Öztel, Fuat Balcı

“…Our results provide strong support for the representational account of interval timing. We provide a new theoretical account of these findings based on the “metric affordances” of the original memory representation formed during training with the original intervals.…”
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Using Real World Evidence to Describe Pulmonary Arterial Hypertension Treatment Patterns, Healthcare Resource Utilization, and Costs Associated with PDE-5 Inhibitor Monotherapy by George Ruiz, Jason Yeaw, Cassandra A. Lickert, Ajita P. De, Rolin L. Wade, Janis Pruett, William Drake

“…At 12 months post index, 41.5% of patients experienced treatment modification. For the index therapy, 47% of patients had ≥80% adherence to therapy. …”
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Quantifying LAGA mutated mouse IgG2a monoclonal antibody with a rapid pepsin digestion enabled immunoaffinity LC/MS/MS assay by Linlin Dong, Susan Chen, Konstantin Piatkov, Dong Wei, Mark G. Qian

“…The approach should be widely applicable for developing popular LAGA mutant-based biological therapeutics.…”
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Task offloading optimization in mobile edge computing based on a deep reinforcement learning algorithm using density clustering and ensemble learning by Yi Qin, Junyan Chen, Lei Jin, Rui Yao, Zidan Gong

“…Opportunistic computing offloading is effective to enhance computing performance in dynamic edge network environments; however, careless offloading of tasks to ESs can lead to WDs preempting network computing resources with limited bandwidth, thereby resulting in inefficient allocation of computing resources. …”
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