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Inactivation of the CMAH gene and deficiency of Neu5Gc play a role in human brain evolution
Published 2025-02-01“…Graphical Abstract During human evolution, humans lost the ability to synthesize Neu5Gc after the inactivation mutation of the gene CMAH. Therefore, Neu5Gc in the human body is a xenoantigen. …”
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ADEQUATE ANTHROPOLOGY OF KAROL WOJTYLA
Published 2018-12-01“…Theoretical basis comprises of Karol Wojtyła’s works written before and during the pontificate, excluding his poetic writing. …”
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Vitamin Bs as Potent Anticancer Agents through MMP-2/9 Regulation
Published 2025-01-01“…Metalloenzymes play pivotal roles in various cellular processes, including DNA repair, cell signaling, and metabolism, making them promising targets for cancer therapy. This review explores the complex interplay between coenzymes, specifically vitamin Bs, and metalloenzymes in cancer pathogenesis and treatment. …”
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A Case of Violent Suicide Attempt in a Context of Myxedema Psychosis following Radioiodine Treatment in a Patient with Graves’ Disease
Published 2019-01-01“…A rapid physical and psychiatric improvement was observed after the initiation of an oral thyroid replacement therapy without relapse after early discontinuation of the antipsychotic treatment. …”
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An Analytic Study on the Enhancement of Heat Transfer with Nanofluid
Published 2025-02-01“…The pertinent parameters analysed in the boundary value problem are magnetic, non-linear stretching parameter, Prandtl number, radiation, Brownian, thermophoresis. The governing sets of PDE’s are converted to a set of ODES using the similarity transformations. …”
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Why Do Tetrapropylammonium Chloride and Sulphate Salts Destabilize the Native State of Globular Proteins?
Published 2014-01-01“…This result is rationalized by the application of a statistical thermodynamic approach (Graziano, 2010). It is shown that the magnitude of the solvent-excluded volume effect, the main contribution for the native state stability, decreases in both aqueous 2 M TPACl solution and aqueous 1 M TPA2SO4 solution. …”
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Digital Transformation and Corporate Total Factor Productivity: Empirical Evidence Based on Listed Enterprises
Published 2021-01-01“…The research provides theoretical basis and empirical evidence for improving corporate TFP from the perspective of digital transformation.…”
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PBC: Animal Models of Cholangiopathies and Possible Endogenous Viral Infections
Published 2012-01-01“…The majority of patients with PBC was reported to have both RT-PCR and immunohistochemistry evidence of human betaretrovirus infection in lymph nodes or in 2008, the patient who developed PBC with high HIV viral load had an antiviral therapy and recovered. To understand the etiology of PBC associated with infection, several factors should be considered and especially animal models may be useful. …”
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Optimization of Job Scheduling in the Cloud Computing Environment Using the Fuzzy Particle Swarm Optimization Algorithm
Published 2020-09-01“…Nowadays, along with the constant increase of using cloud environment by companies and organizations, scheduling jobs in this environment in an optimum way is of prime importance. Therefore, different algorithms have been suggested for assigning tasks to resources in cloud environments; however, most of which do not consider criteria such as balanced load, and reduction of the task completion time. …”
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Exploring Metal Ions as Potential Antimicrobial Agents to Combat Future Drug Resistance in <i>Mycoplasma bovis</i>
Published 2025-01-01“…Further research is essential to explore their standalone and synergistic applications for therapeutic use.…”
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Identification and Clinical Validation of High HSP60 Expression Predicts Poor Prognosis in Patients with Ovarian Cancer
Published 2025-01-01“…HSP60 may serve as a valuable biomarker for prognosis and a potential therapeutic target. Further randomized clinical trials are warranted to explore its role in ovarian cancer progression and treatment strategies.Keywords: HSP60, ovarian cancer, disease-free survival, overall survival, Cox regression model…”
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Migrant's health needs in receiving countries from a bio-psycho-social approach
Published 2018-12-01“…<p>At present, the Chilean government is making an effort to guarantee the new citizens their rights, with different costumes and in general with a different life style. Therefore, it is of great relevance to know their social, biological and psychological needs through the experience in the receiving countries to make optimum health management in the country. …”
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A questão da paixão como condição para a fé no itinerário da obra Temor e tremor
Published 2016-01-01“…Assuming that “becoming a Christian” is the fundamental theme of S. Kierkegaard’s literary production, the purpose of this essay is to outline the concept of passion set forth in Fear and Trembling as a necessary condition for the realization of the dialectical movements that make possible the development of faith. …”
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Multi-stakeholder perspectives of community pharmacies’ extended services in Al Baha province, Saudi Arabia: A qualitative study
Published 2025-12-01“…Another suggestion was that implementing standards for accreditation could create a competitive environment for community pharmacies, granting them well-deserved privileges and enhancing public confidence in the quality and safety of pharmaceutical care. …”
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