Development and functional validation of a disulfidoptosis-related gene prognostic model for lung adenocarcinoma based on bioinformatics and experimental validation by Tao Shen, Tao Shen, Zhuming Lu, Sisi Yang, Dongxi Zhang, Yongwen Ke, Zhuowen Chen, Jinqiang Wu, Jinqiang Wu, Weidong Wu

“…IHC showed elevated TNS4 levels in LUAD tissues, while in vitro TNS4 knockdown reduced both cell proliferation and migration.ConclusionThis study highlights the role of DRGs in LUAD, with a validated gene signature offering new avenues for targeted therapies, potentially improving LUAD treatment outcomes.…”
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A simple and highly efficient protocol for 13C-labeling of plant cell wall for structural and quantitative analyses via solid-state nuclear magnetic resonance by Tasleem Javaid, Akshayaa Venkataraghavan, Matrika Bhattarai, Debkumar Debnath, Wancheng Zhao, Tuo Wang, Ahmed Faik

“…To our knowledge, there is only a very limited set of methods currently available that achieve high levels of 13C-labeling of plant materials using 13CO2, and most of them require large amounts of 13CO2 in larger growth chambers. …”
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Incretin-responsive human pancreatic adipose tissue organoids: A functional model for fatty pancreas research by E. Lorza-Gil, O.D. Strauss, E. Ziegler, K. Kansy, M.-T. Katschke, G. Rahimi, D. Neuscheler, L. Sandforth, A. Sandforth, G. Sancar, B. Kaufmann, D. Hartmann, S. Singer, A.L. Mihaljevic, R. Jumpertz-von Schwartzenberg, J. Sbierski-Kind, T.D. Müller, A.L. Birkenfeld, F. Gerst

“…Conclusions: This novel adipose organoid model is a valuable tool to study the metabolic impact of incretin signalling in pancreatic adipose tissue, revealing potential therapeutic targets of incretins beyond islets. The donor-specific metabolic memory of these organoids enables examination of the pancreatic fat-islet crosstalk in a donor-related metabolic context.…”
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Finite Element Analysis of the Key Component of Chain- type Lifting System by Jin Jiaqi, Liang Yuan, Wang Xianrong

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Designing a Digital Branding Pattern in Healthy Agricultural Products by Abolghasem Mohammadnezhad Ali Zamini, Arezo Ahmadi danyali, Mahmoud Ahmadi Sharif

“…Marketing managers and digital branding experts and consultants were purposefully selected based on theoretical sampling criteria. Theoretical sampling means that participants are selected based on emergent analysis; and the theory that is created from the data is subsequently modified from the data obtained from subsequent participants. …”
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Conservation Voltage Reduction in Distribution Networks: A Comprehensive Review by Ibrahim Alzubi, Saher Albatran, Issam A. Smadi, Salman Harasis

“…This paper bridges the gap between theory and practice by providing a comprehensive and systematic review of CVR research progress from various aspects, including the effects of CVR on the operation and efficiency of both individual loads, such as residential appliances, and composite commercial and industrial loads. …”
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Monitoring and Early Warning of Torrential Flood and Geological Disasters in Wuzhishan City of Hainan and Design of Emergency Reaction System by YU Di, ZHAO Xu-sheng, WANG Shan-lin

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Polydatin protects against DSS-induced ulcerative colitis via Nrf2/Slc7a11/Gpx4-dependent inhibition of ferroptosis signalling activation by Shimin Zheng, Jianbin Yin, Bingbing Wang, Qiujuan Ye, Jialuo Huang, Xinzhi Liang, Junfeng Wu, Hui Yue, Ting Zhang

“…The findings presented herein indicated that PD may serve as a potential therapeutic agent for patients with UC.…”
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Crosstalk between Macrophages and Mesenchymal Stem Cells Regulated by Biomaterials and Its Role in Bone Regeneration by Fan Gong, Thomas Groth, Chenlin Tu, Mingyan Zhao, Xinqia Huang, Jiaqi Chu

“…Impaired bone healing caused by severe trauma, infection, and tumor resection is an extremely common phenomenon. Therefore, the treatment of bone defects represents a major clinical challenge worldwide. …”
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Sparse Gene Coexpression Network Analysis Reveals EIF3J-AS1 as a Prognostic Marker for Breast Cancer by Xin Chen, Zuyuan Yang, Chao Yang, Kan Xie, Weijun Sun, Shengli Xie

“…EIF3J-AS1 may function in an estrogen-independent manner and could be inhibited by the compound FDI-6. Therefore, integrating sparse gene coexpression network and clinicopathological features can accelerate identification and functional characterization of novel prognostic lncRNAs in breast cancer.…”
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Overexpression of SlGRAS7 Affects Multiple Behaviors Leading to Confer Abiotic Stresses Tolerance and Impacts Gibberellin and Auxin Signaling in Tomato by Sidra Habib, Muhammad Waseem, Ning Li, Lu Yang, Zhengguo Li

“…Abiotic stresses remain the key environmental issues that reduce plant development and therefore affect crop production. Transcription factors, such as the GRAS family, are involved in various functions of abiotic stresses and plant growth. …”
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Recent advances in research on common targets of neurological and sex hormonal influences on asthma by Wenting Zhou, Huan Chen, Xinyu Chen, Jing Gao, Wenting Ji

“…Conclusion We summarize several common important targets in the pathways of action of sex hormones and the nervous system in asthma, provide new directions and ideas for asthma treatment, and discuss current therapeutic limitations and future possibilities. Finally, the article predicts future applications of several important targets in asthma therapy.…”
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Normative values of spinal and peripheral proprioception in position sense among healthy adolescents and young adults by Kenney Ki Lee Lau, Kenny Yat Hong Kwan, Jason Pui Yin Cheung, Karlen Ka Pui Law, Arnold Yu Lok Wong, Daniel Hung Kay Chow, Kenneth Man Chee Cheung

“…This prevents further investigation into classifying patients with abnormal proprioception. Therefore, the primary objective was to address the knowledge gap using three-dimensional motion analysis to capture position sense in adolescents and young adults. …”
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A scoping review of substance use brief interventions in Africa. by Florence Jaguga, Sarah Kanana Kiburi, Eunice Temet, Matthew C Aalsma, Mary A Ott, Rachel W Maina, Juddy Wachira, Cyprian Mostert, Gilliane Kosgei, Angeline Tenge, Lukoye Atwoli

“…BIs were defined as those targeting substance use and delivered over 1-4 sessions, or interventions delivered over more than four sessions if the authors referred to them as 'brief'. Results of the review have been summarized descriptively and organized by three broad outcomes: BI effect and feasibility; feasibility and effectiveness of training providers to deliver BIs; Other outcomes i.e. cost-effectiveness, BI adaptation and development, and knowledge attitude and practice of BIs by providers.…”
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Correlating Microbial Dynamics with Key Metabolomic Profiles in Three Submerged Culture-Produced Vinegars by Juan J. Román-Camacho, Inés M. Santos-Dueñas, Isidoro García-García, Teresa García-Martínez, Rafael A. Peinado, Juan C. Mauricio

“…It can be concluded that <i>Komagataeibacter</i> and <i>Acetobacter</i> were not only the predominant genera but also the ones that most influenced vinegar metabolite profiles by using different metabolic strategies for mutual collaboration, and together with other microbial groups, some of them were previously practically unknown in vinegar. …”
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Study on Flood Control Operation of Nanshan Intercepting System by 陈炎林

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Frequency and Causes of Dental Complaints in the Yazd Medical Council Organization between 2017 and 2022 by Yasaman Sabaghzadegan, Sina Amini-Bahabadi, Fatemeh Owlia

“…The information was gathered through observation and by filling out applicable checklists. Subsequently, thedata underwent analysis through  SPSS version 16, utilizing with a chi-square test and Spearman correlation. …”
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Preliminary Research on Reinforcement Schemes for New Composite Dam Structure of Mortar Masonry-Concrete ——A Case Study of Chi'ao Reservoir in Shenzhen City by CHEN Yu, YANG Xiuchun, DU Jiakai, XU Menghua

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First line antiepileptics and their hidden risks - a unique case report on diffuse calvarial thickening and twisted tongue linked to the use of phenytoin and sodium valproate by Sankavi Kaarthic, Selvakumar CJ

“…This case underscores the importance of recognizing rare side effects in patients on long term anticonvulsant therapy.Case presentation: We present two cases of seizure disorder patients who were on first line antiepileptics phenytoin and sodium valproate developed uncommon side effects of diffuse calvarial thickening and lingual dystonia respectively during their follow up. …”
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Analysis of beampattern dwell time for planar frequency diverse array by Hui Chen, Zi‐Hao Li, Wen‐Qin Wang

“…To further study the spatial beampattern dwell time issues, the pulsed‐planar FDA measurement model is first given, and then, the quantitative analysis of beam dwell time which can be affected by observation point location (azimuth, elevation, and range) and array antenna frequency offset coding method for a given pulse transmitting signal is presented. Finally, the theoretical analysis is proved to be consistent with the simulations.…”
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