Valproic acid targets IDH1 mutants through alteration of lipid metabolism by Lubayna S. Elahi, Michael C. Condro, Riki Kawaguchi, Yue Qin, Alvaro G. Alvarado, Brandon Gruender, Haocheng Qi, Tie Li, Albert Lai, Maria G. Castro, Pedro R. Lowenstein, Matthew C. Garrett, Harley I. Kornblum

“…We conclude that targeting fatty acid metabolism through HDAC inhibition and/or FASN inhibition may be a novel therapeutic opportunity in IDH1 mutant gliomas.…”
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ROTOR STRENGTH ANALYSIS AND LIFE CALCULATION OF HEV MOTOR by DENG ChengHao, LIU WeiGuo, LI ZongHua, ZHOU AnJian, SU LinKe

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Saúde urbana no ensino de geografia: um relato de experiência no município de Olinda, Brasil by José Roberto Henrique Souza Soares, Anselmo César Vasconcelos Bezerra

“…Thus, a didactic sequence was elaborate related the geographic knowledge with the problematic of health in the city. Theoretical classes, field activities, mental mapping workshops and evaluation discussions of the teaching strategies used were carried out. …”
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Evidence assessing the diagnostic performance of medical smartphone apps: a systematic review and exploratory meta-analysis by Livia Faes, Lucas M Bachmann, Martin K Schmid, Michael A Thiel, Rahel Buechi, Nicolas S Bodmer, Oliver Job, Kenny R Lienhard

“…Consumers and healthcare professionals should be aware of this when using or recommending them.PROSPERO registration number 42016033049.…”
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Model of effective leadership in public administration by Janez Stare

“…One of the most commonly cited is the leadership potential of the leaders themselves. Leaders as individuals are defined in this manner by their inherited qualities and the personality-trait development they have either received or actually achieved themselves. …”
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Nanoreinforcements of Two-Dimensional Nanomaterials for Flame Retardant Polymeric Composites: An Overview by Shaolin Lu, Wei Hong, Xudong Chen

“…While polymers are often convenient and helpful, their properties often obscure the fire hazards they may pose. Therefore, it is of great significance in terms of safety to study the flame retardant properties of polymers while still maintaining their optimal performance. …”
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English Law Terms: Optimizing Education Process by A. G. Anisimova, M. A. Arkhipova

“…Every term has its particular place among other elements of a system and is related to them in a particular way. A terminological system should be considered as a whole, and there are particular hierarchical relations between its elements. …”
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Considerations on the Use of Exogenous Fibrolytic Enzymes to Improve Forage Utilization by Germán D. Mendoza, Octavio Loera-Corral, Fernando X. Plata-Pérez, Pedro A. Hernández-García, Mónica Ramírez-Mella

“…Digestion of cell wall fractions of forage in the rumen is incomplete due to the complex links which limit their degradation. It is therefore necessary to find options to optimize the use of forages in ruminant production systems. …”
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先秦时期我国水井作用探析 by 贾兵强

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黑龙江省首次证实有小鸥分布 by 鲁长虎, 刘伯文, 王永庆

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The Great Reduction of Equatorial Electrojet During the Solar Eclipse on 14 December 2020 by Kedeng Zhang, Hui Wang

“…Using the equatorial electrojet (EEJ) and plasma measurements from Swarm, zonal winds from the Michelson Interferometer for Global High‐resolution Thermospheric Imaging on Ionospheric Connection Explorer mission, and electron density from the Constellation Observing Systems for Meteorology, Ionosphere, and Climate mission, the temporal responses of EEJ to the total solar eclipse on 14 December 2020, have been examined. …”
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Kinematics Analysis and Simulation of Line-driven Hedge Trimming Manipulator by Xue Zan, Luo Tianhong, Chen Cai

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On the Ideology of the Renovationist Church Groups in the first half of the 1920s: the First All-Russian Congress of the “Union of Church Revival” in 1924 and its main Decisions... by Kulpinov Sergey, Deacon

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Dynamic Analysis of the Blood-Brain Barrier Disruption in Experimental Stroke Using Time Domain in Vivo Fluorescence Imaging by Abedelnasser Abulrob, Eric Brunette, Jacqueline Slinn, Ewa Baumann, Danica Stanimirovic

“…The area differential between the BBB disruption for small and large molecules could potentially be useful as a surrogate imaging marker for assessing perinfarct tissues to which neuroprotective therapies of appropriate sizes could be delivered.…”
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Hybrid precoding and power allocation for mmWave NOMA systems based on time delay line arrays by Gangcan SUN, Xinli WU, Wanming HAO, Zhengyu ZHU

“…Objectives: The antenna structure in conventional millimeter-wave (mmWave) nonorthogonal multiple access(NOMA)systems is based on a high-resolution and high-energy phase shifter modulation network,and how to reduce the system energy consumption while improving the resolution is one of the key problems to be solved. In this thesis, a lowcomplexity and low-power delay line array consisting of switches and delay lines for continuous phase modulation is introduced into the mmWave NOMA system, and the energy efficiency(EE)and spectral efficiency(SE)of the system are investigated. …”
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GUARANTEEING THE ACCES OF THIRD PARTIES TO THE NETWORK INDUSTRIES SPECIFIC INFRASTRUCTURES – A VITAL COMPONENT OF EU'S POLICY IN THE FIELD OF COMPETITION ON THE ENERGY MARKET, IN T... by Iulian BĂICULESCU, Dragoș-Adrian BANTAȘ

“…As both the practical experience and the theoretical constructions of successive generations of practitioners and researchers of the phenomenon of the economy and the legal norms associated with its proper functioning have proven, the most important mechanism for increasing consumer satisfaction in a market, both from the perspective of the quality of the goods and services they benefit from, as well as from that of the prices demanded, is the competition. …”
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T Cell Costimulatory Molecules in Anti-Viral Immunity: Potential Role in Immunotherapeutic Vaccines by Tania H Watts, Edward M Bertram, Jacob Bukczynski, Tao Wen

“…These new developments have important implications for therapeutic vaccine design. In this review the authors discuss the function of T cell costimulatory molecules in immune system activation and their potential for enhancing the efficacy of therapeutic vaccines.…”
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Research on Stepless Speed Change Mechanism of Variable Diameter Pulley and Planetary Compound Transmission by Chuang Yan, Aiping Song, Jianzhou Pan, Ning Mei

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Bullatine A suppresses glioma cell growth by targeting SIRT6 by Zhi Wang, Yushuai Zhu, Can Luo, Fan Zhang, Jiannong Zhao, Chuanyi Fu

“…In summary, our study indicated that BLA is a potential therapeutic agent for glioma that targets SIRT6 to inhibit glioma cell proliferation and induce apoptosis.…”
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Calculation of Air Gap Magnetic Field and Torque of Dual-modulation Axial Magnet Gear Motors by Ge Yanjun, Ma Xueqi, Li Haitao, Long Wei, Yu Han

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