The modern use of hydroxyurea for children with sickle cell anemia by Charles T. Quinn, Russell E. Ware

“… Over the past 40 years, the introduction and refinement of hydroxyurea therapy has led to remarkable progress for the care of individuals with sickle cell anemia (SCA). …”
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STUDY ON ELECTRONIC PACKAGE MINIATURE BALL GRID ARRAY SOLDER JOINTS STRESS AND STRAIN UNDER THREE POINT BENDING by LIANG Ying, HUANG ChunYue, YIN Rui, HUANG Wei, LI TianMing, ZHAO HongWang

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fMRI Analysis on Electroacupuncture on Tongli Acupoint in Healthy People by Lin LU, Wanzhang YANG, Yunhai QIU, Liping YE, Linling LI

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基于连续强度法的不锈钢梁抗剪切性能研究 by 付怡乐, 徐红玉, 焦燏烽

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Physiopathology of Bone Modifications in β-Thalassemia by Carlo Perisano, Emanuele Marzetti, Maria Silvia Spinelli, Cinzia Anna Maria Callà, Calogero Graci, Giulio Maccauro

“…The abnormal regulation of bone metabolism may be related to hormonal and genetic factors, iron overload and iron chelation therapy, nutritional deficits, and decreased levels of physical activity. …”
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Joint security and performance improvement in multilevel shared caches by Amin Sarihi, Ahmad Patooghy, Mahdi Amininasab, Mohammad Shokrolah Shirazi, Abdel‐Hameed A. Badawy

“…Then, a thread‐mapping algorithm to detect such race conditions between a group of threads and resolve them as a countermeasure against the attack is proposed. …”
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Simplified Medication Adherence Questionnaire (SMAQ) for People Living With HIV in a National Hospital in Mexico: Instrument Validation Study by Luis Eduardo Del Moral Trinidad, Luz Alicia González Hernández, Jaime Federico Andrade Villanueva, Pedro Martínez-Ayala, Adriana Valle Rodríguez, Vida Veronica Ruíz Herrera, José Adán Vizcaíno Résendiz, Melva Guadalupe Herrera Godina, Sergio Dominguez-Lara

“… BackgroundAdherence to antiretroviral therapy is a critical component in achieving viral suppression in people living with HIV in addition to increasing overall quality of life. …”
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Aim high, hit ×10: psychological strategies driving the success of South Korean archers by Joonyoung Lee, Suyoung Hwang

“…Deductive analysis applied an 8-step archery model, while inductive coding identified emergent themes. Trustworthiness was ensured through multiple rounds of coding, expert validation, and member checking.ResultsThe findings revealed several key themes across four phases of archery performance. …”
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Application of Rippled Expansion Oil Storage Tank in the Main Transformer of Raise Project by ZHU Fa-rong

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A new paradigm for cancer immunotherapy: targeting immunogenic cell death-related noncoding RNA by Guojuan Sun, Ling He

“…Accordingly, ICD-related ncRNAs hold promise as novel therapeutic targets for optimizing the efficacy of cancer immunotherapy. …”
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Dynamic Simulation on Deflagration of LNG Spill by Biao Sun, Kaihua Guo, Vishnu K. Pareek

“…The CFD model was initially established based on theoretical analysis and then validated by a lab-scale deflagration experiment. …”
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蔡氏疣螈在中国的分布及补遗 by 李慧明 1 杨璧泽 1 池辉云 2 赖任燕 2 刘昌传 2 徐湛荣 2 朱秀芳 2 龚世平 1 陈金平 1

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University students’ ambition levels and vocational tendencies associated with common culture by H. A. Danaa, M. M. Al-mzary, W. N. Halasa, L. M. Obeidat, M. A. Rababah, M. Kh. Al-Alawneh

“…Besides, universities are recommended to focus on ways of developing the ambition level among students by raising parents’ awareness to set a good example to their children, bring them up from an early age to be ambitious and promote their ambition level.…”
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Políticas públicas de juventude e meio ambiente: o que a percepção socioambiental dos jovens pode dizer? by Tarcísio Augusto Alves Silva

“…In this sense, the present proposal aims to reflect on the social and environmental problems identified by high school students in some of the 12 Per-nambuco development regions and, at the same time, to discuss how the environmental awareness of young people can contribute to the establishment of public policies for them.…”
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Exploring the molecular mechanisms of tirzepatide in alleviating metabolic dysfunction-associated fatty liver in mice through integration of metabolomics, lipidomics, and proteomic... by Jinliang Liang, Huanyi Liu, Guo Lv, Xiaotong Chen, Zhaoshou Yang, Kunhua Hu, Hongyan Sun

“…These results suggest that tirzepatide exerts its therapeutic effects on MAFLD by reducing fatty acid uptake, promoting cholesterol excretion, and enhancing mitochondrial-lysosomal function, providing a theoretical basis for a comprehensive understanding of tirzepatide.…”
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Evaluation and Analysis of Soil Temperature Data over Poyang Lake Basin, China by Ming-jin Zhan, Lingjun Xia, Longfei Zhan, Yuanhao Wang

“…Soil temperature reflects the impact of local factors, such as the vegetation, soil, and atmosphere of a region. Therefore, it is important to understand the regional variation of soil temperature. …”
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A Compensação Financeira pela Exploração de Recursos Minerais - CFEM como mecanismo para políticas públicas inclusivas em Parauapebas/PA by Tiago Soares Barcelos, Gabriel Moraes de Outeiro, Maria Amélia Enriquez, Marco Antônio Silva Lima, João Paulo Borges de Loureiro

“…In this debate, "devir" (becoming) is a key concept to understand the forces driving the social transformation of a mineral-based municipality, as mining, being a finite resource, has a limited lifespan. Therefore, the article focuses on the use of CFEM, which has the potential to foster public policies for current and future generations by creating inclusive opportunities, particularly for the vulnerable population excluded from the mineral logic, and leaving a legacy of socio-economic change for the future. …”
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Permeation Peptide Conjugates for In Vivo Molecular Imaging Applications by Kristin E. Bullok, Seth T. Gammon, Stefania Violini, Andrew M. Prantner, Victor M. Villalobos, Vijay Sharma, David Piwnica-Worms

“…These novel permeation peptide conjugates maintain rapid translocation across cell membranes into intracellular compartments and have the potential for targeted in vivo applications in molecular imaging and combination therapy.…”
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Codeine 3-O-demethylase catalyzed biotransformation of morphinan alkaloids in Escherichia coli: site directed mutagenesis of terminal residues improves enzyme expression, stability... by Garrick W. K. Spencer, Xu Li, Kenny W. L. Lam, George Mutch, Fiona H. Fry, Sally L. Gras

“…This mutagenesis study targeted non-conserved N-and C-terminal residues, which were replaced with the equivalent residues from enzyme thebaine 6-O-demethylase. Whole cell biotransformation performance was significantly improved in Escherichia coli expressing codeine 3-O-demethylase mutants, with a ~ 2.8-fold increase in the production of oripavine from thebaine and ~ 1.3-fold increase in the production of morphine from codeine. …”
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Electronically Tunable Transimpedance Instrumentation Amplifier Based on OTRA by Rajeshwari Pandey, Neeta Pandey, Sajal K. Paul

“…The proposed circuit is insensitive to parasitic input capacitances and input resistances due to the internally grounded input terminals of OTRA. Theoretical analysis is verified through PSPICE simulations and experimentation.…”
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