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  1. 11521

    Expanding the therapeutic horizon in acute myeloid leukemia: The role of phosphoinositide-3-kinase-γ inhibition by Soumyajit Das, Mahendra Pratap Singh, Nishant Rai, Sanjit Sah

    Published 2024-12-01
    “…Acute myeloid leukemia (AML) remains a formidable challenge due to its high relapse rate and limited therapeutic options. This study investigates the role of phosphoinositide-3-kinase-γ (PI3Kγ) in AML and explores the therapeutic potential of the PI3Kγ inhibitor, eganelisib, in preclinical models. …”
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  2. 11522
  3. 11523

    Lactylation modulation identifies key biomarkers and therapeutic targets in KMT2A-rearranged AML by Dan Liu, Silu Liu, Yujie Ji, Ziyan Jin, Zhewei He, Mengjia Hou, Dongyang Li, Xiao Ma

    Published 2025-01-01
    “…The study also suggested PI3K inhibitors and Pevonedistat as possible therapeutic options to modulate immune cell infiltration. …”
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  4. 11524

    AI-writing tools in education: if you can’t beat them, join them by Tseng Waverly, Warschauer Mark

    Published 2023-05-01
    “…By teaching our students how to effectively partner with AI, we can better prepare them for the changing landscape of technology use in the world beyond the classroom.…”
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  5. 11525

    Thermodynamic Analysis of the Static Spherically Symmetric Field Equations in Rastall Theory by Hooman Moradpour, Ines G. Salako

    Published 2016-01-01
    “…The restrictions on the Rastall theory due to application of the Newtonian limit to the theory are derived. …”
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  6. 11526

    Renal Effects of Hyperbaric Oxygen Therapy in Patients with Diabetes Mellitus: A Retrospective Study by Martin Sedlacek, Nicole P. Harlan, Jay C. Buckey

    Published 2021-01-01
    “…Hyperbaric oxygen therapy (HBOT) is an adjunctive treatment for patients with diabetic foot ulcers. …”
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  7. 11527
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  11. 11531
  12. 11532
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  14. 11534
  15. 11535

    The Nrf2/Keap1/ARE Pathway and Oxidative Stress as a Therapeutic Target in Type II Diabetes Mellitus by Joshua A. David, William J. Rifkin, Piul S. Rabbani, Daniel J. Ceradini

    Published 2017-01-01
    “…In this review, we outline the role of oxidative damage and the Nrf2/Keap1/ARE pathway in TIIDM, focusing on current and future efforts to utilize this relationship as a therapeutic target for prevention, prognosis, and treatment of TIID.…”
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  16. 11536
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  18. 11538

    Thermodynamic Analysis of CRDI-VCR Type Diesel Engine Fueled with Moringa Oleifera Biodiesel by Vasant Patel, Vyomesh Buch

    Published 2025-05-01
    “…The minimum entropy generation reported for diesel and biodiesel blend MB30 was 0.019kW/K and 0.016 kW/K at higher CR of 18:1.An investigation of the thermodynamics of methyl esters of Moringa oleifera oil mixed with diesel in a VCR-CRDI type engine shows that the combination consists of CR 18:1 and fuel blend MB30 at full load condition offers better performance.…”
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  19. 11539
  20. 11540

    Extensive Use of Interventional Therapies Improves Survival in Unresectable or Recurrent Intrahepatic Cholangiocarcinoma by Ricarda Seidensticker, Max Seidensticker, Kathleen Doegen, Konrad Mohnike, Kerstin Schütte, Patrick Stübs, Erika Kettner, Maciej Pech, Holger Amthauer, Jens Ricke

    Published 2016-01-01
    “…To assess the outcomes of patients with unresectable intrahepatic cholangiocellular carcinoma (ICC) treated by a tailored therapeutic approach, combining systemic with advanced image-guided local or locoregional therapies. …”
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