Constitutive expression of Cas9 and rapamycin-inducible Cre recombinase facilitates conditional genome editing in Plasmodium berghei by Samhita Das, Tanaya Unhale, Carine Marinach, Belsy del Carmen Valeriano Alegria, Camille Roux, Hélène Madry, Badreddine Mohand Oumoussa, Rogerio Amino, Shiroh Iwanaga, Sylvie Briquet, Olivier Silvie

“…Conventional reverse genetic tools cannot be used to study essential genes of the asexual blood stages, thereby necessitating the development of conditional strategies. …”
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Effect of Ion Magnetron Sputtering Method on Scanning Electron Microscopy (SEM)Images of Materials with Different Surface Properties by ZHANG Jie, ZOU Junwen, LIU Xueguang, LI Xiaoying

“…In order to investigate the effect of ion magnetron sputtering parameters on the scanning electron microscopy (SEM) images of nonconductive materials with different surface properties， the advantages and limitations of various ion magnetron sputtering conditions， including target material， sputtering time and sputtering cycles were studied， along with their applicable ranges.Results showed that the gold target exhibited good continuity with large grain nucleation of gold.Due to its high sputtering energy， it easily caused thermal loss on the sample surface， and the gold grains adhered to the surface.Therefore， gold targets were found to be suitable for low -magnification SEM imaging(<10 000) and materials with a certain surface hardness.In contrast， the platinum target showed poor continuity with small platinum grain nucleation and lower sputtering energy.It was more likely to embed into the sample surface， forming a morphological framework， making it suitable for high-magnification SEM imaging (>30 000) and most non-conductive materials.Using a method of fewer， multiple ion magnetron sputtering cycles， reducing the sputtering cycles appropriately not only weakened the effect of the gold film on the material’s morphology and structure but also helped conserve resources and protect the environment.This result provides experimental guidance for researchers to scientifically and accurately analyze SEM images of samples.…”
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Merab Mamardashvili: Event of Thought and Pedagogic Practice by D. G. Ryndin

“…In the light of this connection the article reviews the project of the non-classical ontology of cognition, that Mamardashvili develops in some of his main works.The first part of the article contains an exposition of the problem field of “event” in the context of history and ontology of cognition, as well as reconstruction of the genesis of this theme in Mamardashvili’s philosophy. Mamardashvili describes the classical type of rationality and its “blind spots” – that is, historicity and “evental” character of phenomena of cognition, which cannot be seen in the objectifying gaze of the classical observer. …”
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Endocan in Cancers: A Lesson from a Circulating Dermatan Sulfate Proteoglycan by Maryse Delehedde, Lucie Devenyns, Claude-Alain Maurage, Romain R. Vivès

“…With promising perspectives of clinical applications, Endocan thus appears as an exciting model for on going and future developments of proteoglycan-based approaches in cancer diagnostics and/or therapy.…”
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Assessment of Production and Utilization Practices of Orange-Fleshed Sweet Potatoes (Ipomoea Batatas L.) in Sidama Region, Ethiopia by Miheret Hendebo, Ali Mohammed Ibrahim, Fekadu Gurmu, Hussien Mohammed Beshir

“…Farmers conserve their planting materials by leaving them in the field. This causes the materials to be extensively infested with diseases, insects, and other vertebrate pests. …”
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Application of continuous glucose monitoring system in blood glucose monitoring for patients with type 2 diabetes mellitus (动态血糖监测系统在2型糖尿病患者血糖监测中的应用)... by WANG LI (王丽), WANG Shun (王舜)

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Evaluation Method for Pitting Failure of the Planetary Gear System Under Impact Conditions by Fu Bowei, Yang Jie, Liu Yinghui, Feng Guojin, Zhen Dong

“…Firstly, the contact stiffness model of gear pairs is established based on the analytic geometry method and the Hertz contact theory. Secondly, the impact load is introduced, and the contact force between sun gears and planet gears is solved by the impact function method. …”
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Identification of Molecular Subtypes and Prognostic Features of Breast Cancer Based on TGF-β Signaling-related Genes by Jia Qu, Mei-Huan Wang, Yue-Hua Gao, Hua-Wei Zhang

“…Immune checkpoint inhibitors (ICIs) and pharmacological agents that target TGF-β offer significant potential as therapeutic options for cancer. However, the specific role of TGF-β in prognostic assessment and treatment strategies for breast cancer (BC) remains unclear. …”
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Natural Resource Rent and Financial Development: Testing Financial Resource Curse Hypothesis in Iran by Majid Aghaei, Mahdieh Rezagholizadeh, mohammad abdi, rawa mosavi

“…The impact of natural resource abundance on the overall financial development index in the long term is positive but not statistically significant. Therefore, the hypothesis of the resource curse in Iran is not confirmed. …”
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The effect of supplementation with type I and type III collagen peptide and type II hydrolyzed collagen on pain, quality of life and physical function in patients with meniscopathy... by Ahmet Serhat Genç, Ali Kerim Yılmaz, Berna Anıl, Esra Korkmaz Salkılıç, Enes Akdemir, Berna Güzel, Ahmet Mor, Hacı Ahmet Yarar, Nizamettin Güzel, Lokman Kehribar

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Modeling Acceleration and Deceleration Rates for Two-Lane Rural Highways Using Global Positioning System Data by Vinayak Malaghan, Digvijay S. Pawar, Hussein Dia

“…Several past studies developed acceleration/deceleration rate models as a function of a single explanatory variable. Most of them were spot speed studies with speeds measured at specific locations on curves (usually midpoint of the curve) and tangents to determine acceleration and deceleration rates. …”
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Social media experiences of solo leisure travelers during the travel process: A phenomenological study by Ahmet Elnur, Hakkı Akgün

“…Analysis revealed five key themes: sharing experiences, seeking information, documenting memories, minimal use of social media, and feelings of loneliness and connection. …”
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The Coral Reefs Optimization Algorithm: A Novel Metaheuristic for Efficiently Solving Optimization Problems by S. Salcedo-Sanz, J. Del Ser, I. Landa-Torres, S. Gil-López, J. A. Portilla-Figueras

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Case Report: Management of a case of multidrug-resistant Klebsiella pneumoniae infection in a second-kidney transplant patient by Supreeta R. Shettar, Mahadevaiah Neelambike Sumana, Manjunath S. Shetty, Yogeesh D. Maheshwarappa, Reddy G. Raghukanth, Asha Srinivasan, Dharan P. Vamshi, Gautam Kalyatanda, Swamy G. S. Veerabhadra, Shylaja Eshwarappa Chinchana

“…This approach is critical in overcoming the resistance mechanisms inherent to Klebsiella pneumoniae, thereby improving the likelihood of therapeutic success. …”
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Effects of Physical-Agent Pain Relief Modalities for Fibromyalgia Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials by Yuichiro Honda, Junya Sakamoto, Yohei Hamaue, Hideki Kataoka, Yasutaka Kondo, Ryo Sasabe, Kyo Goto, Takuya Fukushima, Satoshi Oga, Ryo Sasaki, Natsumi Tanaka, Jiro Nakano, Minoru Okita

“…The studies’ physical-agent modalities were low-level laser therapy (LLLT), thermal therapy, electromagnetic field therapy, and transcutaneous electrical nerve stimulation (TENS). …”
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Effect of rifampicin on the lipid profile of albino rats by DE Peters, RN Ichipi-Ifukor

“…Histological  examination of the heart revealed normal architectural structure of the heart after rifampicin administration for 20 and 60days, though pattern of plasma lipid alteration suggests dyslipidemia; therefore plasma lipid profile should be monitored routinely because of the positive relationship between increased dyslipidemia with cardiovascular diseases.…”
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The Influence of the Covid-19 Pandemic on the Professional Identities of Health Care Workers by Shushentha Naidoo, Shaun Denvor Ruggunan

“…Six individuals participated in 60-min semi-structured interviews. Three themes emerged from this study. These themes are; professional strain and identity management, crisis and reconstruction and experiences of Covid-19. …”
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Health education based on precede-proceed model in perioperative functional exercise for patients with lung cancer (基于格林模式的健康教育在肺癌患者围手术期功能锻炼中应用)... by CAI Daoling (蔡道玲)

“…Patients in the observation group had higher score of Functional Assessment of Cancer Therapy-Lung (FACT-L) and dimensional score of lung cancer specific module after intervention compared with those in the control group (P＜0. 01). …”
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Altamira-PA: novos papéis de centralidade e reestruturação urbana a partir da instalação da UHE Belo Monte by José Queiroz de Miranda Neto, José Antônio Herrera

“…As a parameter for this analysis, we considered that Altamira is having a major role in the South East centrality of the Pará state, reaching up to nine urban centres between the Xingu River and the Transamazonica road (BR 230). The theoretical references used in this article are coupled with surveys about the city, urbanism in Brazil and in the Amazon area, with an emphasis on surveys linking urban restructuration and average sized cities. …”
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Protein interference for regulation of gene expression in plants by A. O. Vyacheslavova, I. A. Abdeeva, E. S. Piruzian, S. A. Bruskin

“…For the PtFLC protein, one of the isoforms was found, which is formed as a result of alternative splicing and acts as a negative repressor, binding to the full-length TF PtFLC and therefore regulating the development of the Poncirus trifoliata. …”
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