Mesenchymal Stem Cell-derived Exosomes: Novel Therapeutic Approach for Inflammatory Bowel Diseases by Cheng-mei Tian, Mei-feng Yang, Hao-ming Xu, Min-zheng Zhu, Yuan Zhang, Jun Yao, Li-sheng Wang, Yu-jie Liang, De-feng Li

“…Collectively, MSC-Exos had great potential for cell-free therapy in IBD. However, further studies are required to understand the full dimensions of the complex Exo system and how to optimize its effects.…”
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The Role of Therapeutic Anticoagulation in COVID-19 by Ruth McGovern, Patrick Conway, Isabell Pekrul, Omar Tujjar

“…From the discussion of this case report, however, it can be concluded that despite the plausible theoretical rationale, studies pertaining to the role of empiric therapeutic anticoagulation in this setting fall short of providing compelling evidence. …”
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MicroRNA-219 in the central nervous system: a potential theranostic approach by Nahal Shamaeizadeh, Mina Mirian

“…Despite the recent therapeutic advances in neurological disorders, curative therapy remains a serious challenge in many cases. …”
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Cutaneous Effects of Notch Inhibitor Therapy: A Report of Two Cases by Claire J. Wiggins, Susan Y. Chon

“…As aberrant Notch signaling has been linked to cancerous growth, Notch inhibitors represent a novel category of targeted oncological therapy. Notch pathways in tumor cells may contribute to proliferation or limit apoptosis and differentiation. …”
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Women in Working Life and Overview of Studies on This Theme with “Glass Ceiling” Concept by Ebru Çitil

“…The aim of this study is to examine the concept of "glass ceiling" by considering the theoretical information in this matter and the results of the studies conducted around the world. …”
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Role of Hyperbaric Oxygen Therapy in Prostate Tumor Microenvironment and Cancer Stem Cell Niche by Pranathi Konda, Merrel Holley, Vinoth Kumar Lakshmanan

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Property development in n-alkane and n-alkane eutectic phase change materials for thermal energy storage applications by Cemil Alkan, Erdinç Halis Alakara

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Hypoxia-inducible factor in cancer: from pathway regulation to therapeutic opportunity by Brian M Ortmann

“…HIF’s dysregulation is frequently observed in various cancer types and correlates with increased aggressiveness, metastasis, resistance to therapy and poor patient prognosis. Consequently, understanding the cellular mechanisms underlying HIF activation and its downstream effects has become crucial to developing targeted cancer therapies for improving cancer patient outcomes and represents a key step towards precision medicine.Recent advancements in drug development have led to the emergence of HIF inhibitors, which aim to disrupt HIF-driven processes in cancer providing therapeutic benefit. …”
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Unleashing the potential of a low CpG Passer transposon for superior CAR-T cell therapy by Jianyao Zeng, Yan Sun, Yan Sun, Yuan Fang, Xiaodie Wang, Qian Huang, Pingjing Zhang, Meiqi Shao, Pei Wang, Jingbo Cheng, Meng Di, Tao Liu, Qijun Qian, Qijun Qian, Qijun Qian

“…Additionally, de novo DNA methylation programs promote T cell exhaustion, which poses a significant limitation for CAR-T cell therapy applications.MethodsHigh-throughput liquid protein chip and CBA analyses were utilized to determine the expression levels of inflammatory factors. …”
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TCR-engaging scaffolds selectively expand antigen-specific T-cells with a favorable phenotype for adoptive cell therapy by Marco Donia, Özcan Met, Julie Westerlin Kjeldsen, Sine Reker Hadrup, Inge Marie Svane, Arianna Draghi, Anders Handrup Kverneland, Christina Heeke, Siri Amanda Tvingsholm, Marcus Svensson Frej, Vibeke Mindahl Rafa, Ulla Kring Hansen, Maria Ormhøj, Alexander Tyron, Agnete W P Jensen, Mohammad Kadivar, Amalie Kai Bentzen, Kamilla K Munk, Gitte N Aasbjerg, Jeppe S H Ternander, Tripti Tamhane, Christian Schmess, Samuel A. Funt, Søren Nyboe Jakobsen

“…Journal for ImmunoTherapy of Cancer…”
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How to Use PERMA Model of Positive Psychology in Occupational Therapy to Improve Well-being by Kam Man WONG, Guang ZENG

Subjects: “…occupational therapy…”
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Observation on Therapeutic Effect of Neuromuscular Electrical Stimulation and Rehabilitation Training on Dysphagia Patients Caused by Different Brain Injuries and Effect on Their Hyoid Motion by Yan LI

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Impacts of Thermal Inertia Factor on Adiabatic Decomposition of 40% Mass Content DCP in Ethyl Benzene by Xiaojuan Wu, Liping Chen, Guoning Rao, Wanghua Chen, Ruili Yin

“…DSC experiment showed that ethyl benzene has no effect on the characteristic parameters of thermal decomposition of DCP, such as the temperature of the exothermic peak (Tpeak) and the decomposition energy (Ea), and the thermal decomposition reaction of 40% DCP followed the one-step reaction principle. …”
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<i>Klebsiella pneumoniae</i> Phage M198 and Its Therapeutic Potential by Lika Leshkasheli, Ia Kusradze, Darejan Bolkvadze, Lia Askilashvili, Maria Chichashvili, Giorgi Tsertsvadze, Elisabed Zaldastanishvili

“…This prospect highlights the need for well-characterized therapeutic phages. In this work, we describe a <i>K. pneumoniae</i> phage, which also infects strains of <i>Klebsiella oxytoca</i>. …”
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Construction of a radiogenomic signature based on endoplasmic reticulum stress for predicting prognosis and systemic combination therapy response in hepatocellular carcinoma by Huai-Yu Wu, Shu-Ya Cao, Zheng-Gang Xu, Tian- Wang, Gu-Wei Ji, Ke Wang

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Simulating Study on Mechanical Properties of Rock Wool Board for Thermal Insulation on External Walls by Xiaoguang Li, Jinjin Liu, Xin Fan, Jinyi Qin, Rui Zhang, Ren Cao, Panqi Wang, Xiaoliang Huo

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Comparative Thermal Analysis of Different Cool Roof Materials for Minimizing Building Energy Consumption by Y. Anand, A. Gupta, A. Maini, Avi Gupta, A. Sharma, A. Khajuria, S. Gupta, S. Sharma, S. Anand, S. K. Tyagi

“…The impact of using cool roof technologies on the thermal comfort of the office buildings has been estimated. …”
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Maternal neonicotinoid pesticide exposure impairs glucose metabolism by deteriorating brown fat thermogenesis by Wenwen Zhu, Jiali Fang, Chenbo Ji, Hong Zhong, Tianying Zhong, Xianwei Cui

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Comparison of Ignition Control Techniques in HCCI Engines from Theoretical and Practical Perspectives by Yang Jiaqi

“…This paper aims to delve into the theoretical and practical aspects of ignition control methods in HCCI engines, highlighting the differences and challenges between theoretical models and real-world applications.…”
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Defending Against Advanced Persistent Threats Using Game-Theory. by Stefan Rass, Sandra König, Stefan Schauer

“…Theoretically, these models come with different properties than classical game theoretic models, whose technical solution presented in this work may be of independent interest.…”
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