Merging metabolic modeling and imaging for screening therapeutic targets in colorectal cancer by Niki Tavakoli, Emma J. Fong, Abigail Coleman, Yu-Kai Huang, Mathias Bigger, Michael E. Doche, Seungil Kim, Heinz-Josef Lenz, Nicholas A. Graham, Paul Macklin, Stacey D. Finley, Shannon M. Mumenthaler

“…To exploit this metabolic crosstalk, we integrated a systems biology approach that identified key metabolic targets in a data-driven method and validated them experimentally. This process involved a novel machine learning-based method to computationally screen, in a high-throughput manner, the effects of enzyme perturbations predicted by a computational model of CRC metabolism. …”
Get full text

Evaluation and Treatment of Baseball Pitchers: There’s More to Assess than the Arm by Matthew L Gauthier, Casey A Unverzagt, George J Davies

“…International Journal of Sports Physical Therapy…”
Get full text

Development and feasibility testing of a new device for home-based leg heat therapy in patients with lower extremity peripheral artery disease by Bohyun Ro, MSc, John P. Spence, BBA, Paul A. Spence, MD, Christian Buckley, BS, Raghu L. Motaganahalli, MD, Bruno T. Roseguini, PhD

Subjects: Get full text

Prophylactic and therapeutic effects of EsV3 on atherosclerotic lesions in ApoE−/− mice by Yaze Wang, Hifumi Ohishi, Rongji Wu, Hui Liu, Rong Xu

“…EsV3 was administered in prophylactic (P-EsV3) and therapeutic regimens for 16 and 12 weeks, respectively, with distinct high- and low-dose groups (0.36 and 1.8 g/kg/day). …”
Get full text

Beckerman Stephen and Paul Valentine (eds), Cultures of multiple fathers. The theory and practice of partible paternity in Lowland South America, University Press of Florida, Gainesville, 2002, 291 p., bibl., index, ill., carte by Olivier Allard

Get full text

Pelvic Floor Muscle Training vs. Vaginal Vibration Cone Therapy for Postpartum Dyspareunia and Vaginal Laxity by Federico Villani, Izabella Petre, Florina Buleu, Stela Iurciuc, Luciana Marc, Adrian Apostol, Chiara Valentini, Elisabetta Donati, Tommaso Simoncini, Ion Petre, Cristian Furau

“…Participants were assessed 3 months postpartum (T0) and after 3 months of therapy (T1) at the Pelvic Floor Rehabilitation Clinic of Santa Chiara Hospital, Pisa. …”
Get full text

Identifying the Antecedents of Employee Perceptions of Human Resource Practices Using Signaling Theory by Aryan Gholipour, Mohammad Abooyee Ardakan, Neda Mohammad Esmaeili, Atiyeh Rasouli

Subjects: Get full text

Rediscovery of the waterlily Nymphaea thermarum Eb. Fisch. in Rwanda by Thomas Abeli, Sarah Marie Müller, Siegmar Seidel

Subjects: Get full text

Conglomerated Imiquimod and Metronidazole Incorporated Biodegradable Nanofibrous Mats for Potential Therapy of Cervical Cancer by Chen YP, Chiu CF, Wang CN, Lin CC, Shen CR, Yao YC, Kuo YH, Liu SJ

Get full text

Disease-Specific Autoantibodies Induce Trained Immunity in RA Synovial Tissues and Its Gene Signature Correlates with the Response to Clinical Therapy by Xiaoli Dai, Xiaoqiu Dai, Zheng Gong, Chen Yang, Keqin Zeng, Fang-Yuan Gong, Qiao Zhong, Xiao-Ming Gao

“…We conclude that RA-specific autoantibodies can train monocytes in the inflamed lesion as early as the asymptomatic stage, which may not merely improve understanding of disease progression but may also suggest therapeutic and/or preventive strategies for autoimmune diseases.…”
Get full text

Subproductos de cacao (Theobroma cacao) en la alimentación animal: ¿Una alternativa viable y sostenible? by Ramiro Juan Vega-González, Daniel Castro-Salinas, Fredy Marcial Pajuelo-Risco, César Eduardo Honorio-Javes, Juan Ernesto Hernandez-Valdez

Subjects: “…theobroma cacao…”
Get full text

The relationship between Islamic theology and poetry by Nasufović Sead

Subjects: Get full text

Risk Evaluation of Sewage Treatment PPPABS Projects Using Combination Weight Method and D-S Evidence Theory by Hui Zhao, Zehui Bu, Shengbin Ma

“…Then, the overall risk evaluation method is proposed based on combination weight method and Dempster–Shafer (D-S) evidence theory. Next, Beijing capital Co. Ltd. sewage treatment PPPABS project as a case is employed to verify the feasibility and effectiveness of the proposed method. …”
Get full text

The Effect of Orthodontic Therapy on Periodontal Health: A Review of the Literature by Samah Alfuriji, Nora Alhazmi, Nasir Alhamlan, Ali Al-Ehaideb, Moatazbellah Alruwaithi, Nasser Alkatheeri, Amrita Geevarghese

“…This review aims to evaluate the effect of orthodontic therapy on periodontal health. Data. Original articles that reported on the effect of orthodontic therapy on periodontal health were included. …”
Get full text

Release of Obstructive Prostatic Disease and Improvement of Erectile Dysfunction by Repetitive Prostatic Massage and Antimicrobial Therapy by Bradley R. Hennenfent, Antonio Novak Feliciano

“…With repetitive prostatic massage combined with antimicrobial therapy the urinary obstruction was released, the patient's urinary symptoms resolved, and sexual function improved.…”
Get full text

Cohort profile: the potentially preventable burden of community-acquired pneumonia in South African adults in the era of widespread PCV13 immunisation and antiretroviral therapy roll-out, before and during the COVID-19 pandemic – the multicentre, multimethod PotPrev Study by Jo Southern, Kennedy Otwombe, Eileen Dunne, Khuthadzo Hlongwane, Bradford D Gessner, Michelle Wong, Cheryl Cohen, Anne von Gottberg, Elizabeth Begier, Sharon Gray, Ebrahim Variava, Tumelo Moloantoa, Neil Martinson, Firdaus Nabeemeeah, Nadia Sabet, Lebohang M Mlambo, Phetho Mangena, Pattamukkil Abraham, Floris Swanepoel, Fahima Moosa, Mark Fletcher, Bha Ndungane-Tlakula, Jerusha Naidoo, Minja Milovanovic

“…Purpose In the setting of an established childhood pneumococcal vaccination programme with immediate initiation and treatment of antiretroviral therapy (ART) for people living with HIV (PLWH), the risk of adult pneumococcal community-acquired pneumonia (CAP) is not recently described. …”
Get full text

Side-stepping the guardian of the genome: current cancer therapeutics targeting mutant p53 by Iulianna C. Taritsa, Eric T. Fossel

Subjects: Get full text

Theoretical assessment of the relative incidences of sensitive andresistant tuberculosis epidemic in presence of drug treatment by Silvia Martorano Raimundo, Hyun Mo Yang, Ezio Venturino

“…We identify the steady states of the model toanalyse their stability.We establish threshold conditions for possible scenarios:elimination of sensitive and resistant strains and coexistence of both.We find that the effective reproductive number iscomposed of two critical values, relative reproductive number for drug-sensitiveand drug-resistant strains.Our results imply that thepotential for the spreading of the drug-resistant strain should be evaluated withinthe context of several others factors.We have also found that even the considerably less fit drug-resistant strainscan lead to a high MDR-TB incidence, because the treatment is less effective against them.…”
Get full text

Path and Practice of Gap Management in National Parks: A Comparison Between China and the US and Inspirations Therefrom by Yun MA, Siyuan HE

“…China’s national park planning should reflect on the legitimacy of “gap” and develop a legitimacy evaluation system for human activities, while transiting from merely opening gaps to managing them through classified control and spatial coordination. …”
Get full text

Omics technologies in oral oncology: Integrative approaches for biomarker discovery and therapeutic insights by S. Umamaheswari

Get full text