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  1. 85061
  2. 85062

    Analysis of the correlation between the dose exposure intensity and apatinib in advanced gastric cancer: a retrospective cohort study by Xiao Ma, Xiao Ma, Lan Gao, Siying Che, Chaofeng Tao

    Published 2025-02-01
    “…This study amid to evaluate the correlation between dose exposure intensity and efficacy and safety of apatinib in the treatment of advanced gastric cancer.MethodsWe conducted an observational, retrospective cohort study of patients with advanced gastric cancer who received apatinib targeted therapy in Beijing Friendship Hospital affiliated to Capital Medical University between June 1, 2018, and June 30, 2021. …”
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  3. 85063

    Patient safety culture through the lenses of surgical patients: a qualitative study by Magnhild Vikan, Arvid S. Haugen, Berit T. Valeberg, Ann K. Bjørnnes, Vigdis K. S. Husby, Ellen CT. Deilkås, Stein O. Danielsen

    Published 2025-02-01
    “…We analyzed the data using Braun and Clarke’s method for reflexive thematic analysis, and generated themes by examining patterns of meaning throughout the dataset. …”
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  4. 85064

    Synthesis and protective effect of pyrazole conjugated imidazo[1,2-a]pyrazine derivatives against acute lung injury in sepsis rats via attenuation of NF-κB, oxidative stress, and a... by Zang Binbin, Wang Lihui

    Published 2023-09-01
    “…They exhibited a diverse range of inhibitory activity against NF-ĸB with IC50 ranging from 1 to 94 µmol L–1. Among them, compound 3h [(4-(4-((4-hydroxyphenyl)sulfonyl) phenyl)-5-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl) (8-(methylamino)imidazo[1,2-a]pyrazin-2-yl)methanone] was identified as the most potent NF-κB inhibitor with IC50 of 1.02 µmol L–1. …”
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  5. 85065

    Saussurea costus alleviates ulcerative colitis by regulating the gut microbiota and improving intestinal barrier integrity by Wen-lin Pang, Wen-lin Pang, Tian-gang Li, Tian-gang Li, Yin-ying Wang, Yin-ying Wang, Li-yun Song, Li-yun Song, Li Li, Li Li, Xiao-ya Li, Xiao-ya Li, Yong Qiu, Yong Qiu, Zhong-shan Yang, Zhong-shan Yang

    Published 2025-01-01
    “…In addition, analysis of 16S rRNA gene sequencing indicated that SC reduced harmful bacterial populations, such as Proteobacteria, while simultaneously enhancing the levels of beneficial bacteria like Lactobacillus, thereby contributing to the improvement of UC pathology.ConclusionThis study highlights the therapeutic potential of SC in managing UC through its ability to attenuate inflammatory responses, restore intestinal barrier functionality, and modulate gut microbiota composition, which findings offer insights into potential strategies for advancing UC treatment.…”
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  6. 85066

    Going Through the Motions: American Bodies in Pharrell Williams’s “24 Hours of Happy” by Claude Chastagner

    Published 2018-11-01
    “…Does such a body language point to a pressure to conform and thereby raise questions related to freedom? What can we infer from the emphasis put on happiness in this video, and more broadly in US popular culture and public policies?…”
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  7. 85067
  8. 85068

    PD-L1 positive platelets mediate resistance to immune checkpoint inhibitors in patients with colorectal cancer by Jiacheng Li, Jia Liu, Shifeng Yang, Yu Xia, Qingzhe Meng, Biying Sun, Yansong Liu, Bin Zhao, Jiaqi Jin, Hui Xu, Lihong Wang, Pengxia Zhang, Zhuoxin Cheng

    Published 2025-01-01
    “…Clinical combination treatment with ICIs and antiplatelet agents may be an effective therapeutic strategy for treating CRC.…”
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  9. 85069

    Phylogenetic Analysis of Spike and Envelope Proteins for a Number of Bat Coronaviruses for Understanding the Hypothesis of Possible Origin for the Novel 2019- nCoV by Salar Ibrahim Ali

    Published 2020-12-01
    “…Coronavirus Disease 19 (COVID-19) emergence reveals  globally a great health issue and due to the limited information and knowledge on the origin of this novel coronavirus 2019 (2019-nCoV). Therefore, this study aims to investigate the evolution and analysis of molecular epidemiology for both Spike and Envelope proteins of 20 available complete genome sequences of different bat coronaviruses including 2019-nCoV in order to find out which type of bat coronaviruses is more likely to be the origin of this new 2019-nCoV and also multiple amino acid sequences of Envelope protein for all bat coronaviruses were aligned for the purpose of finding the greater probability of novel 2019-nCoV original host   among bat coronaviruses. …”
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  10. 85070

    Risk assessment of non-point source pollution in tropical watersheds considering water functional zones by Shiyu Xue, Yanhu He, Hao Cai, Jun Li, Lirong Zhu, Changqing Ye

    Published 2025-02-01
    “…However, few studies comprehensively assess the risk of land-based and water-based NPS pollutant loads in tropical watersheds characterized by distinct wet and dry seasons. Therefore, this study employs the Soil and Water Assessment Tool (SWAT) model and integrates the concept of water function zones (WFZ) to comprehensively assess the spatiotemporal characteristics, source apportionment, and wet and dry season-specific risk of NPS pollution in the Wanquan River Basin (WRB), considering both the land surface loading risk and the input risk from adjacent water bodies. …”
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  11. 85071

    Peptides as Versatile Regulators in Cancer Immunotherapy: Recent Advances, Challenges, and Future Prospects by Yu Lei, Jiacheng Liu, Yaowei Bai, Chuansheng Zheng, Dongyuan Wang

    Published 2025-01-01
    “…The diverse functionality of peptides has made them attractive as a therapeutic modality, and the global market for peptide-based therapeutics is witnessing significant growth. …”
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  12. 85072

    Editorial by Jörg Tremmel, Markus Rutsche

    Published 2022-04-01
    “…An unprecedented pandemic calls for an unprecedented reaction and therefore IGJR 1/2021 and 2/2021 are special issues that deal with this disruptive event. …”
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  13. 85073

    Hubungan Dukungan Keluarga Terhadap Manajemen Laktasi Pada Ibu Bekerja by Arlia Purwaningsih, Oswati Hasanah, Wasisto Utomo

    Published 2013-10-01
    “…This result suggest a nurse as a working mother to improve their social environment while breastfeeding to motivate, persuade, and support them on performing optimal lactation management. …”
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  14. 85074

    On Archival Research: Recovering and Rewriting History. The Case of Sarah Parker Remond by Sirpa Salenius

    Published 2021-07-01
    “…The essay includes archival documents, rendering them, now for the first time, accessible to others, and contributes to the rewriting of the stories of such inspirational women as Remond back into the history that erased them.…”
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  15. 85075
  16. 85076

    The Survey of Behavioral Systems in Relation to Test Anxiety: A Comparative Study by Amir ABDOLHOSSEINI, Najmeh SAFARIOLYAEI, Pooyesh GANJI, Ali Morad Heidari GORJI, Roya BALLAZADEH

    Published 2015-12-01
    “…Conclusion: Test Anxiety was corresponded with brain systems behavior theory, and anxiety increased in the avoidance system activation. …”
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  17. 85077

    Research on Upper Bound Limit Stability Analysis of Multi-Step High Steep Slope by Zhen Wang

    Published 2023-01-01
    “…In order to explore the stability of multi-step high steep slope, this paper considers layer distribution of soil and builds a slope failure mechanism which meets requirements of velocity separation based on plastic mechanics principles, then derives the calculation method of external force power and internal energy dissipation power in failure area using numerical analysis theory, and proposes a loop algorithm for slope stability analysis combining upper bound limit analysis theorem and strength reduction principle. …”
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  18. 85078

    Les élites de l’ancien régime libyen : reconfigurations politiques en contexte transnational by Soraya Rahem

    Published 2022-12-01
    “…Heirs to the political ideology developed by Muammar Gaddafi, the regime's elders are trying to reorganize themselves politically from abroad in order to reposition themselves in a post-revolutionary context. …”
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  19. 85079

    Adsorptive Removal of Methylene Blue onto ZnCl2 Activated Carbon from Wood Apple Outer Shell: Kinetics and Equilibrium Studies by N. Bhadusha, T. Ananthabaskaran

    Published 2011-01-01
    “…Influence of agitation time, adsorbent dose, dye concentration, pH and temperature were explored. Two theoretical adsorption isotherms namely Langmuir and Freundlich were used to describe the experimental results. …”
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  20. 85080

    Analyzing and Choosing the Appropriate Model for Issuing Islamic Securities for Financing SMEs by Mohammad Mahdi Faridouni, Mohammad Tohidi, Milad Isaei

    Published 2023-06-01
    “…Financing has always been one of the main challenges of SMEs in Iran. Therefore, developing financial instruments for these companies and reducing their dependence on bank financing is always one of their essential needs. …”
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