Multifunctional drug delivery nanoparticles for combined chemotherapy/chemodynamic/photothermal therapy against colorectal cancer through synergistic cuproptosis/ferroptosis/apoptosis by Xiuzhang Yan, Heshi Liu, Lei Guo, Chang Liu, Shichen Zhang, Xue Wang, Yixin Tang, Rui Zhou, Xin Jiang, Erlei Wang, Shuohui Gao, Caina Xu

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Efficacy and safety of anti-CD38 monoclonal antibodies-based therapy versus standard therapy in newly diagnosed multiple myeloma patients: a systematic review and meta-analysis by Muhammad Osama, Muhammad Haris Khan, Safeena Khan, Amna Hussain, Ammara Tahir, Mehran Ullah, Abdullah Afridi, Ubaid Ullah, Wajeeh Ur Rehman

“…Therapeutic Advances in Hematology…”
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A Problem of theory, or a theory of pressures by Simon Burton

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A Framework for Promoting Passive Breast Cancer Monitoring: Deep Learning as an Interpretation Tool for Breast Thermograms by Mohamad Firouzmand, Keivan Majidzadeh, Maryam Jafari, Shahpar Haghighat, Rezvan Esmaeili, Leila Moradi, Nima Misaghi, Mahsa Ensafi, Fatemeh Batmanghelich, Mohammadreza Keyvanpour, Seyed Vahab Shojaedini

“…This study aims to introduce a dataset of breast thermograms.Material and Methods: In this study, thermographic images of breast cancer from Iranian samples were prepared and confirmed due to the limited number of breast thermogram databases.  …”
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The Effect of Statins and Other Cardiovascular Medication on Ischemia-Reperfusion Damage in a Human DIEP Flap Model: Theoretical and Epidemiological Considerations by M. G. W. van den Heuvel, A. Bast, A. W. Ambergen, R. R. W. J. van der Hulst

“…Chronic use of statins or other cardiovascular medication didnot decrease the occurrence of I/R related complications after DIEP surgery. Therefore, research should be aimed at evaluating short-term pre-treatment with statins.…”
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HAPLOIDENTICAL TRANSPLANT WITH POST-TRANSPLANT CYCLOPHOSPHAMIDE FOR ACUTE MYELOID LEUKAEMIA AND MYELODYSPLASTIC SYNDROMES PATIENTS: THE ROLE OF PREVIOUS LINES OF THERAPY. by Daniele Avenoso, Fabio Serpenti, Liron Barnea Slonim, Styliani Bouziana, Francesco Dazzi, Guy Hannah, Michelle Kenyon, Varun Mehra, Austin Kulasekararaj, Pramila Krishnamurthy, Mili Naresh Shah, Sharon Lionel, Antonio Pagliuca, Victoria Potter

“…The median OS in patients with >2 previous lines of therapy and ≤2 lines of therapy was 16 and 49 months, respectively. …”
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Delivery Parameter Variations and Early Clinical Outcomes of Volumetric Modulated Arc Therapy for 31 Prostate Cancer Patients: An Intercomparison of Three Treatment Planning Systems by Shinichi Tsutsumi, Masako N. Hosono, Daisaku Tatsumi, Yoshitaka Miki, Yutaka Masuoka, Ryo Ogino, Kentaro Ishii, Yasuhiko Shimatani, Yukio Miki

“…We created volumetric modulated arc therapy (VMAT) plans for 31 prostate cancer patients using one of three treatment planning systems (TPSs)—ERGO++, Monaco, or Pinnacle—and then treated those patients. …”
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Onset of thermosolutal reactive-convection in an Ellis fluid saturated porous layer by Vinod Y․, K.R. Raghunatha, Dilsora Abduvalieva, Manish Gupta

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Coupled Coincidence Point and Coupled Fixed Point Theorems via Generalized Meir-Keeler Type Contractions by Hassen Aydi, Erdal Karapınar, İnci M. Erhan

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A theory of nonlinear wave loading on offshore structures by Lokenath Debnath, Matiur Rahman

“…A theoretical study is made of the nonlinear wave loading on offshore structures using the diffraction theory of hydrodynamics. …”
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Charge heterogeneity of therapeutic monoclonal antibodies by different cIEF systems: views on the current situation by Alessandro Ascione, Marcello Belfiore, Jaana Vesterinen, Mihaela Buda, Wolf Holtkamp, Francesca Luciani

“…Therapeutic mAbs show a specific “charge fingerprint” that may affect safety and efficacy, and, as such, it is often identified as a critical quality attribute (CQA). …”
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Targeted therapy for pancreatic ductal adenocarcinoma: Mechanisms and clinical study by Heng‐Chung Kung, Jun Yu

Subjects: “…neoadjuvant therapy…”
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Anaerobic external combustion thermal engines by V. I. Karagusov

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Switch to Aflibercept in Diabetic Macular Edema Patients Unresponsive to Previous Anti-VEGF Therapy by Filipe Mira, Manuel Paulo, Filipe Henriques, João Figueira

“…The aim was to evaluate the efficacy of aflibercept in patients with diabetic macular edema (DME) unresponsive to prior anti-VEGF therapy. Methods. Retrospective review of DME unresponsive to previous anti-VEGF switched to aflibercept with 3 months of follow-up. …”
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The Effect of Low-Level Laser Therapy on Accelerating Tooth Movement in Orthodontic Patients: A Randomized Controlled Trial by Mohammad K. Alam, Mohammad Y. Hajeer, Dalia A. Alanazi, Shahad A. Alanazi, Haya O. Alruwaili

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Chloramphenicol-infused N-vinyl-based soft contact lenses for therapeutic and optical applications by Lina M. Shaker, Ahmed Alamiery, Abdulamier Ahmed Abdulamier, Wan Nor Roslam Wan Isahak

“…Key analysis including UV–Vis spectra, refractive index (RI) measurement, scanning electron microscopy (SEM) images, and Fourier-transform infrared (FTIR) charts confirmed the lenses’ physical, chemical, and therapeutic performance. The fabricated lenses demonstrated an impressive RI range of 1.49 to 1.53 preserving visual clarity and achieving over 95% visible light transmittance while effectively blocking UV radiation. …”
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FEATURES OF STUDENT SELF-IDENTIFICATION IN THE ERA AFTER THE "THERAPEUTIC TURN" by Elena S. Balashova, Anna V. Bogacheva, Anna V. Khizhnaya

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Potential Therapeutic Drugs for Parkinson’s Disease Based on Data Mining and Bioinformatics Analysis by Chuan Xu, Jiajun Chen, Xia Xu, Yingyu Zhang, Jia Li

“…The objective is to search potential therapeutic drugs for Parkinson’s disease based on data mining and bioinformatics analysis and providing new ideas for research studies on “new application of conventional drugs.” …”
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Violences à l’acte, violences dans l’acte : pour une histoire des théâtres féministes états-uniens by Madeleine Planeix-Crocker

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Genome-wide CRISPR-based screen identifies E2F transcription factor 1 as a regulator and therapeutic target of aristolochic acid-induced nephrotoxicity by Ziqi Liu, Huan Gao, Guoliang Li, Yongjiang Yu, Mengxing Cui, Honghao Peng, Xinchao Guan, Xue Zhang, Zhihan Zhang, Xiaoyu Shen, Shen Chen, Daochuan Li, Liping Chen, Yongmei Xiao, Wen Chen, Lili Liu, Qing Wang

“…In vitro and in vivo models confirmed that CBD inhibits AAI-induced upregulation of E2F1, thereby suppressing p53-mediated apoptosis. In conclusion, this study highlights the crucial role of E2F1 in AAI-induced renal cell apoptosis and identifies CBD as a novel therapeutic candidate for mitigating AAI nephrotoxicity.…”
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