Showing 6,221 - 6,240 results of 139,491 for search 'the*', query time: 0.29s Refine Results
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    NOS inhibition sensitizes metaplastic breast cancer to PI3K inhibition and taxane therapy via c-JUN repression by Tejaswini Reddy, Akshjot Puri, Liliana Guzman-Rojas, Christoforos Thomas, Wei Qian, Jianying Zhou, Hong Zhao, Bijan Mahboubi, Adrian Oo, Young-Jae Cho, Baek Kim, Jose Thaiparambil, Roberto Rosato, Karina Ortega Martinez, Maria Florencia Chervo, Camila Ayerbe, Noah Giese, David Wink, Stephen Lockett, Stephen Wong, Jeffrey Chang, Savitri Krishnamurthy, Clinton Yam, Stacy Moulder, Helen Piwnica-Worms, Funda Meric-Bernstam, Jenny Chang

    Published 2024-12-01
    “…As a result, combined NOS and PI3K inhibition with taxane targets MpBC stem cells and improves survival in patient-derived xenograft models relative to single-/dual-agent therapy. Similarly, biopsies from MpBC tumors that responded to L-NMMA+taxane therapy showed a post-treatment reversal of epithelial-to-mesenchymal transition and decreased stemness. …”
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  4. 6224
  5. 6225

    The Monotone Contraction Mapping Theorem by Joseph Frank Gordon

    Published 2020-01-01
    “…This paper provides a version of the Banach fixed-point theorem in a complete metric space.…”
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  6. 6226

    Network Anomaly Detection System with Optimized DS Evidence Theory by Yuan Liu, Xiaofeng Wang, Kaiyu Liu

    Published 2014-01-01
    “…In this model, we add weights for each senor to optimize DS evidence theory according to its previous predict accuracy. …”
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    RAS/RAF/MEK/ERK and PI3K/PTEN/AKT Signaling in Malignant Melanoma Progression and Therapy by Ichiro Yajima, Mayuko Y. Kumasaka, Nguyen Dinh Thang, Yuji Goto, Kozue Takeda, Osamu Yamanoshita, Machiko Iida, Nobutaka Ohgami, Haruka Tamura, Yoshiyuki Kawamoto, Masashi Kato

    Published 2012-01-01
    “…To find better approaches to therapies for patients, understanding these MAPK and AKT signaling mechanisms of melanoma development and progression is important. …”
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  10. 6230

    N-Doped Graphene Quantum Dot Nanoparticle Synthesis of Optical Active Thermal Stable Polyurea Nanocomposites Using Polybutadiene Chain Modification by Zahra Rahmatpanah, Mir Mohammad Alavi Nikje, Maryam Dargahi

    Published 2022-01-01
    “…Nanocomposites were prepared using 1–3 weight percent of graphene N-quantum dot nanoparticles in the polymer matrix. 1H-NMR and FT-IR spectroscopy techniques elaborated successful synthesis of primary polymer binder, polyurea and nanocomposites. Thermal degradation and characteristics were investigated using the TGA/DTG and DSC methods; lower degradation rates with progressed thermal stabilities as well as proportionate thermal characteristics with wider thermal service range were obtained especially in 3 wt% nanocomposite. …”
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    Critical Combinations of Higher-Order Terms in Einstein-Maxwell Theory and Compactification by Nahomi Kan, Kiyoshi Shiraishi

    Published 2015-01-01
    “…We discuss the role of a particular combination of higher derivative terms in higher dimensional theories, particularly in the background of spontaneous compactification. …”
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  13. 6233

    The Role of the Patient Information Leaflet in Patients’Medication Therapy: A Case Study within the Kumasi Metropolis of Ghana by Frederick W. A. Owusu, Genevieve Naana Yeboah, Rahel Adutwiwah Aboagye, Cedric Dzidzor K. Amengor, Philomena Entsie

    Published 2020-01-01
    “…A large number of the patients who were given the PI leaflets indicated that it did not provide them with the needed information.…”
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  14. 6234

    Effectiveness of Single-Tablet Combination Therapy in Improving Adherence and Persistence and the Relation to Clinical and Economic Outcomes by Carly J. Paoli, Jörg Linder, Khushboo Gurjar, Deepika Thakur, Julie Wyckmans, Stacy Grieve

    Published 2024-01-01
    “…**Background:** Single-tablet combination therapies (STCTs) combine multiple drugs into one formulation, making drug administration more convenient for patients. …”
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  15. 6235

    Predicting hepatocellular carcinoma outcomes and immune therapy response with ATP-dependent chromatin remodeling-related genes, highlighting MORF4L1 as a promising target by Chao Xu, Litao Liang, Guoqing Liu, Yanzhi Feng, Bin Xu, Deming Zhu, Wenbo Jia, Jinyi Wang, Wenhu Zhao, Xiangyu Ling, Yongping Zhou, Wenzhou Ding, Lianbao Kong

    Published 2025-01-01
    “…Conclusion ACRRGs, particularly MORF4L1, play crucial roles in modulating HCC progression, offering new insights into the molecular mechanisms driving HCC and potential therapeutic targets. Our findings advocate for the inclusion of chromatin remodeling dynamics in the strategic development of precision therapies for HCC.…”
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  16. 6236

    Une situation ouverte en mathématiques : rapports dialectiques entre Théorie - Expérimentation - Contingence by Christine Del Notaro

    Published 2011-03-01
    “…The observation of the effective practices allowed us to bring to light a phenomenon in our doctoral thesis, which we named the saturation of the environment (“saturation du milieu”). …”
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    CREEP FAILURE ANALYSIS OF THERMAL RECOVERY WELLHEAD by CAO XuXiang, YAN TingJun, WANG TingYi, LI Feng

    Published 2021-01-01
    Subjects: “…Thermal recovery wellhead…”
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  19. 6239

    Using Artificial Intelligence to Analyze Nature of Science Themes: Einstein and Eddington Documentary Film Example by Yusuf Kartal, Munise Seckin-Kapucu

    Published 2024-10-01
    “…In this context, although it seems pretty difficult to extract the nature of science themes on limited data with the Latent Dirichlet Allocation algorithm, it is possible that the artificial learning models to be used in addition to the Latent Dirichlet Allocation algorithm can detect the nature of science themes. …”
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