Drug treatment alters performance in a neural microphysiological system of information processing by Bradley Watmuff, Forough Habibollahi, Candice Desouza, Moein Khajehnejad, Alon Loeffler, Koby Baranes, Noah Poulin, Mark Kotter, Brett J. Kagan

“…Abstract Assessment of pharmacological intervention on in vitro neural systems often emphasizes molecular and structural changes. …”
Get full text

Identification of aging-related biomarkers for intervertebral disc degeneration in whole blood samples based on bioinformatics and machine learning by Zi-hang Li, Shi-pian Li, Shi-pian Li, Ya-hao Li, Yu-cheng Wang, Zhen-yu Tang, Kai-yang Xu, Xiao-rong Li, Zhen Tan, Jiao-yi Pan, Jin-tao Liu, Hong Jiang, Zhi-jia Ma, Yu-xiang Dai, Yu-xiang Dai, Yu-xiang Dai, Peng-fei Yu

“…IntroductionAging is characterized by gradual structural and functional changes in the body over time, with intervertebral disc degeneration (IVDD) representing a key manifestation of spinal aging and a major contributor to low back pain (LBP).MethodsThis study utilized bioinformatics and machine learning approaches to identify aging-related biomarkers associated with IVDD in whole blood samples. …”
Get full text

Nerve growth factor: what can surgeons and oncologists learn from a neurological and psychological biomarker? by Fei Xiong, Ben-li Xiao, Qi Wang, Kun Liu, Hong-wei Wu, Chao Jing, Kui-nan Tong, Zhong-tao Zhang, Wei Guo

“…Conclusions Systemic NGF-targeted therapies have significant articular and neurological toxicity, indicating the critical need for localized intervention strategies depending on the expression level of NGF and TrkA to balance antitumour efficacy with protective requirements for nerve structures and innervation.…”
Get full text

HelpMe: Early Detection of University Students' Mental Health Issues Using a Chatbot-Integrated Dashboard by Nadia Abdul Wahab, Ahmad Asyraf Zainudin, Aznoora Osman, Norfiza Ibrahim, Abdul Hapes Mohammed

“…Future enhancements will focus on refining chatbot interactions and optimizing real-time dashboard functionality to better support student well-being …”
Get full text

Arthroscopic Lateral Ulnar Collateral Ligament Plication/Reconstruction With Augmented Lateral Collateral Ligament Imbrication by Christos Koukos, M.D., Dominique Schoeps, M.D., Joachim Windolf, M.D., In-Ho Jeon, PhD, M.D., Cristina Zolog, M.D., Konstantinos Ditsios, PhD., M.D., David Latz, M.D.

“…Posterolateral rotatory instability (PLRI) is a chronic condition resulting from damage to the lateral ulnar collateral ligament (LUCL) and related structures causing painful restrictions and instability in elbow movement. …”
Get full text

Barriers to suicide research are also barriers to suicide prevention:Insights from conducting a mixed-methods project in oncology by Judith Hirschmiller, Tamara Schwinn, Jörg Wiltink, Manfred E. Beutel, Rüdiger Zwerenz, Elmar Brähler, Mareike Ernst

“…Throughout recruitment and implementation, we documented the barriers encountered and systematically analyzed them.We identified three main categories of obstacles toward the research endeavor that also hold meaning for the efficacy of suicide prevention: First, suicidal thoughts and behaviors are not (allowed to be) an issue in oncology, subsuming the denial of their occurrence, the minimization of their relevance, the alleged appropriateness of the construct to oncology, and the rejection of responsibility; second, prevailing suicide myths, in particular of iatrogenic harm; and third, strong, negative emotional reactions undermining dialogue.We interpret these experiences against previous considerations of dysregulated responses to suicidal patients in the healthcare setting and analyze their causes and functions. These findings highlight the urgent need for structured education on suicide prevention across medical disciplines, particularly in oncology. …”
Get full text

A Prospective Randomized Pilot Study on the Efficacy of a Dietary Supplementation Regimen of Vitamin E and Selenium for the Prevention of Fluoroquinolone-Induced Tendinopathy by Oana-Maria Mișcă, Liviu-Coriolan Mișcă, Bogdan Huzum, Andreea-Adriana Neamţu, Simona Cerbu, Daniel-Raul Chioibaș, Petrișor Zorin Crăiniceanu, Andrei Gheorghe Marius Motoc

“…Ultrasound analysis revealed reduced tendon thickness and neovascularization, supporting structural recovery. Although the incidence of tendinopathy was lower in the interventional group (13.3% vs. 40%), statistical significance was not reached, possibly due to the small sample size. …”
Get full text

Fiber Visualization with LIC Maps Using Multidirectional Anisotropic Glyph Samples by Mark Höller, Kay-M. Otto, Uwe Klose, Samuel Groeschel, Hans-H. Ehricke

Get full text

Legal consequences, measures of prevention and reduction of medical malpractice cases (errors) by A. O. Yanchuk, A. O. Zaporozhchenko, I. P. Katerynchuk, S. O. Kuznichenko, A. V. Kryzhanovska

“…For a more complete understanding of cases of legal consequences the following regulatory measures of prevention of medical malpractice cases are necessary: establishment of an effective system of prudential internal control of defects in the medical care; specialised training for medical personnel on methods of detection of medical malpractices, their prediction and prompt elimination of possible consequences; instrumental, functional and system-structural measures for reducing risks of medical malpractice, namely: actions for reducing medical errors caused by system determinants (failures, disorders, etc.), actions for reducing medical errors made in prescribing and applying medicaments, medical errors happened because of the medical intervention, surgical in particular; improvement of the legal support of guarantees of patients and doctors rights for a safe delivery of medical aid and prevention of medical errors.…”
Get full text

The Impact of Brain-Based Teaching on Iranian EFL Learners' Vocabulary Retention and Recall by Davoud Amini, Mahsa Rahmani Asl, Abolfazl Ghasemzadeh

“…The brain-based learning (BBL) approach refers to a learning method which attends to the structural and functional properties of the brain when involved in learning. …”
Get full text

Delayed repair for complex genital trauma following sexual assault in a 3-year-old female with late presentation for care: a case report by Raha Maroyi, Denis Mukwege, Lisa Doble, Robert Andrianne

“…A total of 2 weeks later, surgical intervention was performed, which resulted in improved short- and long-term outcomes in terms of the vulvar cosmetic, functional, and psychological aspects. …”
Get full text

Leveraging artificial intelligence for diagnosis of children autism through facial expressions by Mahmood A. Mahmood, Leila Jamel, Nazik Alturki, Medhat A. Tawfeek

“…ResNet152 reached the highest accuracy rate of 89% when functioning independently. This paper develops a hybrid deep-learning model by integrating ResNet152 with Vision Transformers (ViT) to achieve better classification performance. …”
Get full text

Skill set or mind set? Associations between health literacy, patient activation and health. by Samuel G Smith, Laura M Curtis, Jane Wardle, Christian von Wagner, Michael S Wolf

“…Participants (n = 697) were recruited from multiple US-based health centers. During structured face-to-face interviews, participants completed the Test of Functional Health Literacy in Adults (TOFHLA), the Patient Activation Measure (PAM), the SF-36 physical health summary subscale, and Patient Reported Outcomes Measurement Information Service (PROMIS) short form subscales for depression and anxiety.…”
Get full text

Challenging behaviours in interprofessional teamwork in the intensive care unit: a qualitative content analysis of focus group interviews by Magnus Hultin, Karin Jonsson, Maria Härgestam, Christine Brulin

Get full text

Neuroprotective potential for mitigating ischemia-reperfusion-induced damage by Zi Ye, Runqing Liu, Hangxing Wang, Aizhen Zuo, Cen Jin, Nan Wang, Huiqi Sun, Luqian Feng, Hua Yang

“…Reperfusion following cerebral ischemia causes both structural and functional damage to brain tissue and could aggravate a patient’s condition; this phenomenon is known as cerebral ischemia-reperfusion injury. …”
Get full text

The Benefits of Dog-Assisted Therapy for Children With Anxiety by Andrea Wu, Ruth Wei

“…Therefore, further research is required regarding the effectiveness and clinical implications of the nature, type of intervention, length, and duration of dog-assisted therapy.…”
Get full text

Describing Pulmonary Nodules Using 3D Clustering by Amera Al-Funjan, Farid Meziane, Rob Aspin

“…This paper combines algorithms to cluster and define nodule’s features in 3D visualization. Applying some 3D functions to the objects, clustered using the K-means technique of CT lung images, provides a 3D visual exploration of the nodule shape and location. …”
Get full text

Evaluation of the Results of Glaucoma Surgery Using Optical Coherent Tomography (Literature Review) by I. I. Khusnitdinov

“…It allows assessing the level of retention of intraocular fluid, determining the functional activity, the location of drains and drainage devices both in the early and late postoperative period.…”
Get full text

“The questions made me realize how many times I could have been saved and removed from that situation”: The experiences of patients attended to by paramedics for intimate partner v... by Rory A. Marshall, Nicole Merritt, Tori N. Stranges, Stephen Bartlett, Simon Sawyer, Paul van Donkelaar

“…Corresponding solutions were safe and equitable paramedic behaviour, respectful conduct, mandatory education and training, develop functional infrastructure, develop functional transitions, and utilize techniques to engage with perpetrators and survivors. …”
Get full text

Schizophrenia Detection and Classification: A Systematic Review of the Last Decade by Arghyasree Saha, Seungmin Park, Zong Woo Geem, Pawan Kumar Singh

“…The review evaluates the use of both Machine Learning (ML) and Deep Learning (DL) methods across multiple modalities, including Electroencephalography (EEG), Structural Magnetic Resonance Imaging (sMRI), and Functional Magnetic Resonance Imaging (fMRI). …”
Get full text