A qualitative study on optimizing influenza vaccination services and strategies for people aged 60 and above in Shanghai by WANG Xiaolan, YANG Tian, XUE Caoyi, WU Linlin, FEI Yi, YANG Xiaoguang, XU Biao

“…Furthermore, systematic interventions and publicity efforts should be effectively integrated with social media and the functions of neighborhood committees.…”
Get full text

Factors Influencing Primary Care Physicians’ Adjustment of Oral Anti-Diabetic Drugs in Patients with Type 2 Diabetes Mellitus: A Qualitative Research Study by Natasha Sheng Yeng Leng, Shera Chaterji, Aminath Shiwaza Moosa, Patricia Ching Yen Chia, Lay Geok Lian, ZhengHua Li, Natalie Ming Foong Hooi, Beth Shin Rei Lau, Ngiap Chuan Tan

“…Clinical decision support functionality in the electronic medical record (EMR) system prompted PCPs to select the type of OADs during the consultation. …”
Get full text

Migration, Urbanism and Health: Moving Toward Systems-Informed Policy and Practice [version 2; peer review: 1 approved, 2 approved with reservations] by Karen Lau, Furio Honsell, Sally Hargreaves, Rita Sà Machado, Palmira Immordino, Cathy Zimmerman, Anna Ziersch, Yang Xiao, Irene Torres, Stefania Pascut

“…Therefore, effective urban health interventions must be inclusive of migrant populations and expand beyond healthcare services. …”
Get full text

Evaluation of the clinical and cost effectiveness of intermediate care clinics for diabetes (ICCD): a multicentre cluster randomised controlled trial. by Andrew Wilson, Joseph Paul O'Hare, Ainsley Hardy, Neil Raymond, Ala Szczepura, Ric Crossman, Darrin Baines, Kamlesh Khunti, Sudhesh Kumar, Ponnusamy Saravanan, ICCD trial group

“…Community based, intermediate care clinics for diabetes (ICCDs) were considered one solution and are functioning across the UK. However, there is no randomised trial evidence for the effectiveness of such clinics.…”
Get full text

Evaluation of SCORED as a diagnostic tool for early detection of chronic kidney disease (CKD) and End-stage renal disease (ESRD): A hospital-based study by Osama F Mosa

“… Background: Chronic Kidney Disease (CKD) and End-Stage Renal Disease (ESRD) are significant public health problems characterized by structural or functional anomalies of the kidneys. CKD is considered one of the ma-jor non-communicable diseases and its prevalence is increasing rapidly in Saudi Arabia. …”
Get full text

Evaluating Perceived Resilience of Urban Parks Through Perception–Behavior Feedback Mechanisms: A Hybrid Multi-Criteria Decision-Making Approach by Zhuoyao Deng, Qingkun Du, Bijun Lei, Wei Bi

“…Factors such as environmental psychological resilience, functional diversity, and visual permeability show a significant path influence and priority intervention value. …”
Get full text

Neural Correlates of Motor Recovery after Robot-Assisted Training in Chronic Stroke: A Multimodal Neuroimaging Study by Cheng Chen, Kai Yuan, Xin Wang, Ahsan Khan, Winnie Chiu-wing Chu, Raymond Kai-yu Tong

“…We adopted EEG-informed fMRI technique to understand the functional regions sensitive to training intervention. …”
Get full text

Identification of lipid metabolism-related genes in dapagliflozin treated rats with diabetic cardiomyopathy by bioinformatics by Xun Huang, Yunhong Wang, Rong Wan, Zhigang You, Lin Huang

“…Differential expression analysis of model vs. control and intervention vs. model samples was performed to obtain differentially expressed genes (DEGs), and the result was recorded as DEGs-Model and DEGs-Intervention. …”
Get full text

Examining the comorbidity network of Internet addiction and depression: the role of effortful control on their bridge symptoms in adolescents by Tomoya Hirota, Tomoya Hirota, Masaki Adachi, Masaki Adachi, Rei Monden, Hiroyuki Mori, Hiroyuki Mori, Michio Takahashi, Michio Takahashi, Kazuhiko Nakamura, Kazuhiko Nakamura

“…Additionally, the study examines the association between effortful control (EC) and bridge symptoms, providing insights for interventions.MethodsA school-based survey was conducted among 7th to 9th-grade students in Japan. …”
Get full text

Insight into the effects of Omega-3 fatty acids on gut microbiota: impact of a balanced tissue Omega-6/Omega-3 ratio by Bo Zou, Dan Zhao, Shuang Zhou, Jing X. Kang, Jing X. Kang, Bin Wang, Bin Wang

“…Emerging evidence suggests that Omega-3 polyunsaturated fatty acids (PUFAs) are essential structural and functional nutrients that significantly influence the composition and function of the gut microbiota, a key mediator of host health. …”
Get full text

Mechanisms and regulatory pathways of recessive land use transition by TAN Lin, CHEN Lan

“…These three forms are closely interconnected and interact with each other. (2) Implicit land use transition is the process of significant and fundamental changes in efficiency, functional, and power forms. It is rooted in the intervention system composed of regional resource endowments, engineering and technological systems, policy and institutional environments, cultural value recognition, and socio-economic development, featuring inherent relevance and dynamic adjustability. (3) Based on the underlying logic of “comprehensive land benefits - dominant land functions - land development rights”, regulatory pathways with element-coordinated governance, classification-based management guidelines, and well-improved institutional structure are constructed, which facilitate recessive land use transition. …”
Get full text

Investigating amygdala nuclei volumes in military personnel with post-traumatic stress disorder, major depressive disorder, and adjustment disorder: A retrospective cross-sectional... by Thiemo Knaust, Dagmar Tarnogorski, Matthias B D Siebler, Philipp Skiberowski, Christian Moritz, Helge Höllmer, Holger Schulz

“…Abnormalities in these amygdala nuclei are implicated in PTSD and may distinguish it from other disorders like MDD and AdjD, where these mechanisms are less central. Investigating structural differences in specific amygdala nuclei could enhance diagnostic precision and inform targeted interventions.…”
Get full text

Butylated hydroxytoluene (BHT) induces zebrafish spinal cord defects and scoliosis by inhibiting the hedgehog pathway by Hao Cheng, Yulian Li, Fasheng Liu, Shanshan Zhu, Li Chen, Huiqiang Lu, Xiaowen Shi, Ling Huang

Get full text

The Physical Activity in the Management of Heart Failure with Reduced Ejection Fraction A Review of Current Evidence and Recommendations by Natalia Smyl, Mateusz Teofilak, Olga Śpiołek, Jan Siwiec, Aleksandra Słowikowska, Julia Szatkowska, Marcelina Paula Sztyler-Krąkowska, Agnieszka Alicja Wąsowicz, Franciszek Kędziora, Dariusz Paweł Fabian

“…Advancements in pharmacological therapy is abundant, but there is mounting recognition for non-pharmacological approaches such as structured physical activity for improving life quality and functional capability. …”
Get full text

The Legacy of COVID-19: Hospital Fear Led to the Delayed Diagnosis of an Ovarian Tumor with Massive Ascites and Extensive Abdominal Necrosis by Janos Szederjesi, Calin Molnar, Claudiu Molnar-Varlam, Dorin Dorobanțu, Mihai Claudiu Pui, Matild Keresztes

“…To relieve pressure and improve respiratory function, an abdominal drain was inserted, releasing 72 L of ascitic fluid over five days. …”
Get full text

Neuroprotective effects of phenylacetylglycine via β2AR on cerebral ischemia/reperfusion injury in rats by Wenjie Hu, Xueyan Kuang, Yao Zhang, Yimin Luo, Litao Zhang

“…This study evaluated the function and the underlying mechanisms of PAGly in a rat cerebral ischemia/reperfusion (I/R) injury model. …”
Get full text

Multidomain Connectivity as a Marker of HIIT-Induced Adaptation in Elite Youth Soccer Players: A Correlational Mapping Approach by Moses Gnanasigamani, Agnieszka Kaczmarek, Jarosław Nosal, Eugenia Murawska-Ciałowicz, Paweł Chmura

“…HIIT elicited statistically significant improvements in aerobic capacity, buffering efficiency, and perceptual-cognitive function, with a notable emergence of cross-domain associations. …”
Get full text

Crystallographic fragment screening reveals ligand hotspots in TRIM21 PRY-SPRY domain by Yeojin Kim, Aleksandar Lučić, Christopher Lenz, Frederic Farges, Martin P. Schwalm, Krishna Saxena, Thomas Hanke, Peter G. Marples, Jasmin C. Aschenbrenner, Daren Fearon, Frank von Delft, Andreas Krämer, Stefan Knapp

“…The high-resolution structural data and observed binding modes across the different sites highlight the versatility of the PRY-SPRY domain as a target for small-molecule intervention. …”
Get full text

Augmented Reality and Computational Simulations for the Preprocedural Planning of Transcatheter Aortic Valve Replacement After Previous Transcatheter Mitral Valve Replacement by Roberta Scuoppo, Chiara Catalano, Eleonora Costagliola, Stefano Cannata, Salvatore Pasta, Caterina Gandolfo

“…The use of AR in the operating room enhanced the understanding of device positioning, offering a new dimension of precision of the complex cardiovascular intervention. This study concludes that integrating AR, 3D printing, and computational simulations into preprocedural planning for high-risk structural intervention can significantly improve procedural outcomes by enhancing accuracy, safety, and operator confidence.…”
Get full text

Intra action review of the cholera outbreak response in Kadoma city, Zimbabwe, 2024 by Clayton Munemo, Chido Zibanayi, Hamilton Gomba, Precious Banda, Sarah Tengawarima, Sikhanyisiwe Moyo, Daniel Chirundu

“…These included the use of the IMS to provide structured coordination, marking the first activation of all five core IMS functions for a cholera outbreak response in Kadoma. …”
Get full text