Changes in postural stability induced by a ball-and-board game designed from a systems perspective by Anaëlle Cheillan, João Milho, Pedro Passos

“…Abstract Background Postural behavior can be understood from a systems perspective, emerging from complex interactions within the agent’s body system and the agent-environment system, where inherent variability enables adaptive and functional solutions to balance perturbations. Recent studies have recommended that lower limbs rehabilitation programs should be addressed from a systems perspective for both clinical assessment and intervention. …”
Get full text

What are risk sciences? by Runhuan Feng

“…We propose a three-dimensional structure for understanding risk sciences: (1) identification and assessment (systematic recognition, evaluation, and modeling of risks); (2) mechanism and strategy (functional tools and governance plans for risk intervention); and (3) behavior and decision (psychological, cognitive, and strategic responses to uncertainty). …”
Get full text

Measuring health-related quality of life: a qualitative study of mental health patients’ experiences of impacts of mental health issues by Yeujin Ki, Andrew Athan Mcaleavey, Janne-Merete Torset Øien, Tron Anders Moger, Christian Moltu

“…Additionally, the impact of unpredictability on daily functioning and the role of sleep difficulties should be incorporated. …”
Get full text

Nutrition and Exercise in Critical Illness Trial (NEXIS Trial): a protocol of a multicentred, randomised controlled trial of combined cycle ergometry and amino acid supplementation... by Daren K Heyland, Andrew Day, G John Clarke, Catherine (Terri) Hough, D Clark Files, Marina Mourtzakis, Nicolaas Deutz, Dale M Needham, Renee Stapleton

“…We hypothesise that this novel combined intervention will (1) improve physical functioning at hospital discharge; (2) reduce muscle wasting with improved amino acid metabolism and protein synthesis in-hospital and (3) improve patient-reported outcomes and healthcare resource utilisation at 6 months after enrolment. …”
Get full text

Connecting the Dots: Linking Centrality Measures to Peer Perceptions in Elementary School Friendship Networks by Prochnow Tyler, Keightley Samuel, Patterson Megan S., Lease Michele

“…This study highlights the complex interplay between structural positions in social networks and peer perceptions of social functioning. …”
Get full text

Herb-Derived Products: Natural Tools to Delay and Counteract Stem Cell Senescence by Provvidenza M. Abruzzo, Silvia Canaider, Valeria Pizzuti, Luca Pampanella, Raffaella Casadei, Federica Facchin, Carlo Ventura

“…In particular, with aging, stem cells (SCs) in situ exhibit a diminished capacity of self-renewal and show a decline in their functionality. The identification of interventions able to prevent the accumulation of senescent SCs in the organism or to pretreat cultured multipotent mesenchymal stromal cells (MSCs) prior to employing them for cell therapy is a main purpose of medical research. …”
Get full text

Hybrid closed-loop systems for managing blood glucose levels in type 1 diabetes: a systematic review and economic modelling by Asra Asgharzadeh, Mubarak Patel, Martin Connock, Sara Damery, Iman Ghosh, Mary Jordan, Karoline Freeman, Anna Brown, Rachel Court, Sharin Baldwin, Fatai Ogunlayi, Chris Stinton, Ewen Cummins, Lena Al-Khudairy

“…Treatment with insulin is aimed at replicating the function of the pancreas to manage hyperglycaemia and avoid hypoglycaemia. …”
Get full text

A quantitative study to evaluate the controls and accountability measures in place to alleviate the leadership and governance challenges impacting the realization of the National H... by Samuel Vuyo Mokoena, Panjasaram Naidoo

“…Main outcome The main outcome of the study was to determine the requisite interventions to deal with challenges that affect governance and/or leadership functions in the implementation of the NHI. …”
Get full text

Iodine Status in the Colombian Population and the Impact of Universal Salt Iodization: A Double-Edged Sword? by Hernando Vargas-Uricoechea, María Virginia Pinzón-Fernández, Beatriz Eugenia Bastidas-Sánchez, Elisa Jojoa-Tobar, Luis Eduardo Ramírez-Bejarano, Julián Murillo-Palacios

“…Nevertheless, there is a remarkable rate of iodine excess among the country’s population, which, at least hypothetically, represents a higher risk for developing functional and structural disorders of the thyroid gland. …”
Get full text

Barriers and facilitators to optimal sepsis care – a systematized review of healthcare professionals’ perspectives by Lea Draeger, Carolin Fleischmann-Struzek, Sabine Gehrke-Beck, Christoph Heintze, Daniel O. Thomas-Rueddel, Konrad Schmidt

“…Conclusions This review suggests that, without limitation, interventions that provide continuous provider education as well as standard communication channels between interdisciplinary and intersectoral providers have great potential to improve structural deficiencies in sepsis care. …”
Get full text

The Acceptability of Occupational Therapy Using Zones of Regulation™ Concepts in an Equine Environment to Autistic Children by Jacqueline M. Browne, Sarah Jean Reega, Ellen M. Rankins, Arlene A. Schmid, B. Caitlin Peters

“…Autistic children often have impaired self-regulation which can impact daily functioning and life outcomes. Occupational Therapy Using Zones of Regulation™ Concepts in an Equine Environment (OT-ZOR-Equine) is a standardized intervention that integrates both the Zones of Regulation™ curriculum and horses into occupational therapy to address self-regulation in autistic children. …”
Get full text

Physicians’ experiences of assessing and supporting fatigued patients in primary care: a focus group study by Conrad Samuelsson, Lisa Gunnarsson, Frank Svärdman, Christian Rück, Elin Lindsäter

“…Abstract Background Fatigue is a common symptom in primary healthcare, affecting 10–30% of patients, and is associated with increased healthcare consumption and functional disability. There is a lack of standardised guidelines to assess and treat patients with fatigue, and little is known about how patients are currently managed in primary healthcare. …”
Get full text

A Linkable, Polycarbonate Gut Microbiome‐Distal Tumor Chip Platform for Interrogating Cancer Promoting Mechanisms by Danielle S.K. Brasino, Sean D. Speese, Kevin Schilling, Carolyn E. Schutt, Michelle C. Barton

“…Organ‐on‐chip platforms, which model minimal functional units of tissues and can tightly control communication between them, are ideal platforms to study these relationships. …”
Get full text

Genome-wide characterization of the Eceriferum (CER) gene family in barley (Hordeum vulgare L.) by Bahman Panahi, Rasmieh Hamid, Feba Jacob

“…Collectively, these findings offer valuable insights into the functional roles of CER genes in barley and identify promising candidates for genetic interventions aimed at improving stress tolerance in cereal crops.…”
Get full text

The emotional surge: in-depth qualitative exploration of rumination and emotional turbulence in non-suicidal self-injurers by Soulat Khan, Soulat Khan, Tasnim Rehna, Tayyab Ali Butt

“…Non-suicidal self-injury (NSSI) is an emerging pathological condition among emerging adults, causing significant distress and hindering daily life functioning. The increasing prevalence of NSSI highlights its importance as a crucial area requiring clinical attention. …”
Get full text

The Photo- and Phonosensitivity Avoidance Behavior Scales: Evaluating Clinical Utility in Pediatric Primary Chronic Headache by Allison M. Smith, Megan N. Silvia, Hannah Rogan, Alyssa A. Lebel

“…Over time, avoidance behaviors can inadvertently increase functional disability, suggesting the importance of their thorough consideration. …”
Get full text

The Adoption and Scaling of Climate-Smart Agriculture Innovation by Smallholder Farmers in South Africa: A Review of Institutional Mechanisms, Policy Frameworks and Market Dynamics by Mary Funke Olabanji, Munyaradzi Chitakira

“…The analysis highlights the importance of secure land rights, functional farmer cooperatives, effective NGO involvement, and inclusive governance structures in facilitating CSA adoption. …”
Get full text

Assessing the school food environment and its role on healthy eating behaviours among school age children in Dar es Salaam, Tanzania. by Nyabasi Makori, Dyness Kejo, Hoyce Mshida, Beatrice Bachwenkizi, Devotha Mushumbusi, Zahara Daudi, Monica Chipungahelo, Ai Zhao, Anselm P Moshi

“…Findings highlight the need for interventions to improve food offerings and promote healthier food choices around schools.…”
Get full text

MONITORING OF MORPHOLOGICAL EFFECTS AUTOLOGICAL MESENCHIMAL STEM CELLS, TRANSPLANTED IN LIVER WITH VIRUS CYRROSIS (clinical observation) by S. P. Lukashyk, O. V. Aleinikova, V. M. Tsyrkunov, Y. I. Isaikina, R. I. Кravchuk

“…Autologous transplantation of mesenchymal bone marrow stem cells reduces the degree of destructive changes in hepatocytes, the severity of fibrosis and contributes to the improvement of the morpho-functional state of the liver, and therefore, it can be recommended as an important component of medical interventions.…”
Get full text

Transforming Alzheimer’s Disease Diagnosis: Implementing Vision Transformer (ViT) for MRI Images Classification by Dian Kurniasari, Muhammad Dwi Pratama, Akmal Junaidi, Ahmad Faisol

“…Early detection of AD is crucial for timely intervention, as the disease significantly impacts cognitive functions and daily activities. …”
Get full text