Protocol for a multisite randomised trial of Hand–Arm Bimanual Intensive Training Including Lower Extremity training for children with bilateral cerebral palsy: HABIT-ILE Australia... by Roslyn N Boyd, Leanne Sakzewski, Mark Chatfield, Yannick Bleyenheuft, Iona Novak, Catherine Elliott, Sarah Reedman, Cathy Morgan, Kerstin Pannek, Jurgen Fripp, Prue Golland, David Rowell, Robert Stuart Ware

“…Primary outcomes will be the Gross Motor Function Measure and ABILHAND-Kids. Secondary outcomes will be brain structural integrity, walking endurance, bimanual hand performance, self-care, mobility, performance and satisfaction with individualised goals, and QOL. …”
Get full text

Inferior vena cava obstruction secondary to hepatic alveolar echinococcosis: a case report by Jingxin Yan

“…Interventional treatments significantly could improve liver function, thereby facilitating future treatment options. …”
Get full text

McIndoe Vaginoplasty in MRKHS: Case Report and Literature Review by Newton Ashish Shah, Manish Yadav, Suman Verma, Digraj Yadav, Aalok Kumar Yadav, Asmita Ghimire, Hima Rijal, Poonam Koirala

“…Neovagina creation is an effective surgical intervention for young females seeking to restore sexual function.…”
Get full text

Data mining methods application in reflexive adaptation realization in e-learning systems by A. S. Bozhday, Y. I. Evseeva, A. A. Gudkov

“…Finding such regularities and their subsequent analysis will make it possible to reorganize the structure of the system in a more optimal way and without human intervention, which will prolong the life cycle of the software and reduce the costs of its maintenance. …”
Get full text

Effectiveness Of The Core Activation And Rehabilitation Exercises For Knee Osteoarthritis - Program (CARE -KOA©) Among Patients Diagnosed With Knee Osteoarthritis. [version 4; peer... by Saurabh Mehta, Ajit R. Mahale, Dias Tina Thomas, Prajwal Prabhudev Mane, Atmananda S Hegde, Charu Eapen

“…Recent research highlights the role of kinetic chain and core muscle involvement in disease progression, yet evidence for structured core activation protocols such as CARE-KOA© remains limited.This study addresses this gap by evaluating the effectiveness of CARE-KOA©, which specifically targets proximal stability and biomechanical deficits in KOA, aiming to enhance pain, function, and core endurance beyond conventional approaches. …”
Get full text

Identification of biomarkers and target drugs for melanoma: a topological and deep learning approach by Xiwei Cui, Xiwei Cui, Jipeng Song, Qingfeng Li, Jieyi Ren

“…Advanced network analysis tools were employed to identify structural disparities and functional module shifts. …”
Get full text

Cross-cultural insights into internet addiction and mental health: a network analysis from China and Malawi by Mengze Li, Yidi Wang, Bin Liu, Xiaoli Ni, Zhujing Ma, Fengzhan Li, Tifei Yuan, Hongyi Chen, Zhongying Wu, Qiannan Jia, Lei Song, Yinchuan Jin, Qun Yang

“…In Malawi, addressing functional impairments related to academic and work performance is crucial, while in China, interventions should focus on emotional and relational aspects.…”
Get full text

Discovery of non-covalent rhinovirus 3Cpro inhibitors by molecular docking, in vitro assays, molecular dynamics simulations and DFT analyses by Susu Zhang, Susu Zhang, Keli Zong, Jiajun Ruan, Xiaojing Liu, Xu Zhao, Youzhi Zhang, Chun Hu, Xingzhou Li

“…Human rhinovirus 14 (HRV-14) is a leading cause of the common cold, with its 3C protease (3Cpro) playing a crucial role in viral replication by cleaving polyproteins into functional proteins and enzymes. This makes 3Cpro a promising target for therapeutic intervention. …”
Get full text

Spider Cage Therapy's Impact on GMFM-88 in Iraqi Infants with Cerebral Palsy in Two Rehabilitation Centers by Nizar Jassim, Amenah Mohammed, Hayder Abbood, Naeem Almashhadani

“…The intervention consisted of structured sessions within the spider cage aimed at improving motor function. …”
Get full text

3D-printed porous tantalum for acetabular reconstruction in complex primary arthroplasty and revision of hip by Zonghan Wang, Zonghan Wang, Zonghan Wang, Ze Wang, Ze Wang, Ze Wang, Lingchuan Gu, Lingchuan Gu, Lingchuan Gu, Ying Zhang, Ying Zhang, Ying Zhang, Tiao Su, Tiao Su, Tiao Su, Jiangming Luo, Jiangming Luo, Jiangming Luo, Chengjun Huang, Chengjun Huang, Chengjun Huang, Xiaoyuan Gong, Xiaoyuan Gong, Xiaoyuan Gong, Yang Peng, Yang Peng, Yang Peng, Guangxing Chen, Guangxing Chen, Guangxing Chen

“…The porosity of the tantalum structure promoted the growth of new bone tissue into the implant, improving its stability and durability. …”
Get full text

Dysbiosis of Gut Microbiota in Ankylosing Spondylitis Patients by Yang L, Wang K, Liu B, Chen T, Ma T, Cui Z, Zhang D, Zhang S, Liu X, Shen J, Lu H

“…Bioinformatic processing and statistical analysis were performed to assess the microbial community structure, diversity, and function.Results: The study revealed significant differences in gut microbiota composition between AS patients and healthy controls. …”
Get full text

Neural correlates of device-based sleep characteristics in adolescents by Qing Ma, Barbara J. Sahakian, Bei Zhang, Zeyu Li, Jin-Tai Yu, Fei Li, Jianfeng Feng, Wei Cheng

Get full text

A család ereje: A házasságban élés és a nagycsaládos lét kapcsolata a jóllét különböző mutatóival by Andrea FERENCZI, Zsuzsanna KÖVI, Veronika MÉSZÁROS

“…CONCLUSIONS – The findings highlight the complex interplay between gratitude and family as well as religious background. The protective function of dispositional gratitude may be especially relevant for the development of psychological prevention and intervention programmes, as it can contribute both to the enhancement of perceived social support and the maintenance of subjective well-being. …”
Get full text

Reconstruction of the Nasal Wings with the Inverted Flap Technique. Presentation of Two Cases by Raquel Rojas Bruzón, Juan Carlos Quintana Díaz, Yulexis Hechavarría Jiménez

“…Flaps allow the reconstruction of defects by restoring nasal shape and function. The classic method for reconstructing the ala nasal is the nasolabial flap. …”
Get full text

A Combined Weighting Method Based on Hybrid of Interval Evidence Fusion and Random Sampling by Ying Yan, Bin Suo

“…Cumulative probability function constructing and random sampling processes do not require any human intervention or judgment. …”
Get full text

Ruminative and mood associations for age differences in social and directive reasons to think and talk about life experiences. by Jorge J Ricarte, Laura Ros, Jose M Latorre, Tom J Barry

“…These reminiscence processes were also differentially associated with depression symptoms between age groups when tested in structural equation models. In older participants, but not young participants, the directive function was negatively associated with depression severity; in young participants, but not old participants, the social function was negatively associated with depression severity. …”
Get full text

DEVELOPMENT AND IMPLEMENTATION OF CLUSTER POLICY: RUSSIAN AND INTERNATIONAL PRACTICE by Yu. Vertakova, V. Plotnikov, Yu. Polozhentseva

“…They differ in extent of the state intervention. The cluster policy has to be implemented taking into account specifics of spatial structure of economy of the countries and regions. …”
Get full text

Differential effects of electroacupuncture and manual acupuncture on spontaneously hypertensive rats: insights from intestinal microbiota and metabolomics by Ji-Peng Liu, Long-Teng Tu, Ke-Zhen Yang, Yin-Yin Li, Yu Gong, Bing-Xuan Han, Chuan Liu, Tian-Qi Xia, Yu Liu, Xiao-Min Hao, Bing-Nan Yue, Jing Zhang, Bing-Hui Wang, Gui-Rong Luo, Qing-Guo Liu, Meng Xu

“…EA and MA influence the composition of intestinal microbiota in SHRs, aligning the microbial structure more closely with that of the WKY group. …”
Get full text

Neonatal scrotochesis following artificial rupture of membrane in breech delivery by Abdelrahman S. Elnour, Alaa Algurashe, Selma Karsani, Amal Alfatih, Moataz Idriss, Omer Ibrahim

“…Birth trauma refers to structural or functional impairments in newborns caused by mechanical forces during labour and delivery, with breech presentation significantly increasing the risk of neonatal injuries. …”
Get full text

Exploring Therapists’ Approaches to Treating Eating Disorders to Inform User-Centric App Design: Web-Based Interview Study by Pamela Carien Thomas, Pippa Bark, Sarah Rowe

“…Barriers to recommendation include patient safety, data privacy, and a perception that they may not be effective. Many existing interventions have limited functionality or do not differ much from manual cognitive behavioral therapy (CBT) or self-help books, which may not adequately support the therapeutic process or sustain user engagement. …”
Get full text