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Psychometric properties of the Chinese version of scales of knowledge, attitude, and practice of self-care for patients with arteriovenous fistula: a translation and verification s...
Published 2025-04-01“…Hemodialysis remains a critical life-sustaining treatment for CKD patients, with arteriovenous fistulas (AVFs) being the most commonly used vascular access. The long-term functionality of AVFs relies heavily on patients’ self-care abilities, encompassing their knowledge of maintenance practices, appropriate attitudes toward care, and the implementation of effective self-care behaviors. …”
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1242
Validation of the de Morton Mobility Index for measuring mobility related activities in Hungarian institutionalized older adults
Published 2025-07-01“…Maintaining institutionalized older people’s functional capacity and delaying its decline requires effective interventions. …”
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1243
Gene therapy prevents onset of mitochondrial cardiomyopathy in neonatal mice with Ndufs6 deficiency
Published 2025-05-01“…Additionally, AAV9-hNdufs6 gene therapy initiated at an early stage increased Ndufs6 expression in cardiac tissue, preserved mitochondrial structure and function, prevented cardiomyocyte fibrosis through modulation of the AMPK/Drp1 signaling pathway. …”
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1244
A modern view on the mechanisms of diabetic cardiomyopathy development and the its modification options
Published 2019-11-01“…The article is an analytical review of clinical studies of structural and functional cardiac changes in patients with diabetes. …”
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1245
Tool Used to Assess Co-Benefits of Nature-Based Solutions in Urban Ecosystems for Human Wellbeing: Second Validation via Measurement Application
Published 2025-01-01“…In recent years, nature-based solutions have been used in urban regeneration interventions to improve the adaptation and resilience of these places, contributing to improved environmental quality and cultural ecosystem functions, including people’s physiological, social, and mental health and wellbeing. …”
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1246
Regulation of intestinal flora by Suaeda salsa extract ameliorates hyperglycemia in a mouse model of type 2 diabetes mellitus
Published 2024-12-01“…Taken together, these findings demonstrate that SSE can alleviate T2DM and its complications by improving glycemia-related indicators and modulating the structure of intestinal flora.…”
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1247
Correlation between mitral annular plane systolic excursion (MAPSE) at different degrees of ejection fraction in patients with diabetes mellitus
Published 2024-09-01“…Diabetic cardiomyopathy is characterized by myocardial structure and function abnormality in the absence of other cardiovascular risk factors. …”
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1248
Synergizing GIS and genetic algorithms to enhance road management and fund allocation with a comprehensive case study approach
Published 2025-02-01“…The research is structured around three key objectives: (1) develop a detailed GIS-based road management database incorporating inspection data and attributes of road infrastructure for proactive M&R decision-making; (2) efficiently allocate funds to maintain service delivery on deteriorated roads; and (3) pinpoint the optimal type and timing of M&R interventions to boost the condition and performance of the road segments. …”
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1249
Investigating the regulation of the miR-199a-3p/TGF-β/Smad signaling pathway by BSHXF drug-containing serum combined with ADSCs for delaying intervertebral disc degeneration
Published 2025-04-01“…BSHXF restored TGF-β/Smad pathway activity by downregulating miR-199a-3p expression, thereby improving disc structure and function. This integrated approach offers a novel multi-target intervention strategy for IDD, demonstrating significant therapeutic potential.…”
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1250
Assessment of right ventricular endocardial fibroelastosis in fetuses with critical pulmonary stenosis and pulmonary atresia with intact ventricular septum
Published 2025-01-01“…Among the ten patients who underwent fetal cardiac intervention (FCI), the restoration of the TV z-score was more significant in Grade 2 RV EFE fetuses than in Grade 1 EFE fetuses. …”
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1251
Muscle-to-action mapping for intuitive training of muscle synergies in post-stroke upper-limb rehabilitation
Published 2025-04-01“…Functional improvements were reflected in the Fugl-Meyer Assessment for the Upper Extremity and Wolf Motor Function Test scores, which increased by 3.36 and 6.45 points, respectively. …”
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1252
An Efficient Process for the Management of the Deterioration and Conservation of Architectural Heritage: The HBIM Project of the Duomo of Molfetta (Italy)
Published 2024-12-01“…Subsequently, it was possible to develop an efficient Scan-to-HBIM workflow, where the Heritage BIM (HBIM) project has fulfilled the function of a database by incorporating and organizing all the information (graphic and non-graphic) to optimize the tasks of auscultation, identification, classification, and quantification and, in turn, facilitating the parametric modeling of unique structures and architectural elements. …”
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1253
P88 | REGENERATIVE MEDICINE, REHABILITATION AND CYTO-HISTOCHEMISTRY: RECENT EVALUATIONS OF INTEGRATED TREATMENTS
Published 2025-08-01“…The current experiences and guidelines, published on the best international papers, are currently applied in our daily work following the Italian rules and laws. What is interventional non-surgical regenerative orthopedics? …”
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1254
Non-Invasive Retinal Biomarkers for Early Diagnosis of Alzheimer’s Disease
Published 2025-01-01“…As an extension of the central nervous system, the retina offers a distinctive opportunity for non-invasive brain structure and function assessment. Considering their shared embryological origins and the vascular and immunological similarities between the eye and brain, alterations in the retina may indicate pathological changes in the brain, including those specifically related to AD. …”
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1255
Bioinformatics analysis of JUP in patients with acute myocardial infarction and its potential application in clinical prognostic evaluation
Published 2025-05-01“…BackgroundJunctional Plakoglobin (JUP) is a critical protein involved in intercellular junctions, playing a significant role in maintaining the structure and function of myocardial cells. However, the expression of JUP in acute myocardial infarction (AMI) and its potential applications in prognostic evaluation of patients remain underexplored. …”
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1256
METAB‐HTX: prospective, longitudinal cohort study evaluating cardiac and systemic metabolism after heart transplantation
Published 2025-08-01“…Kidney and liver function and structural alterations will be evaluated. …”
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1257
FOXOs and their roles in acute and chronic neurological disorders
Published 2025-04-01“…Here we summarize the structure, posttranslational modifications, and translocation of FOXOs linking to their transcriptional control of cellular functions, survival, and death, emphasizing their role in regulating the cellular response to some acute insults and chronic neurological disorders. …”
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1258
Decellularized Adipose Matrix Rejuvenates Photoaged Skin through Immune Microenvironment Modulation
Published 2025-01-01“…Current clinical interventions primarily target structural defects, while immune modulation remains underexplored. …”
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1259
“Locality – Adaptation” Research of Hydropower Resettlement Communities in the Jinsha River Basin: A Case Study of Ludila Hydropower Station
Published 2025-04-01“…At the settlement scale, the Mask Region-based Convolutional Neural Network (Mask R-CNN) deep learning model is utilized to identify architectural spatial features, categorizing three typical building types: traditional pitched-roof buildings, uniformly planned flat-roof buildings, and color steel plate-modified structures. Through multi-source data fusion (including remote sensing, demographic statistics, and compensation records) and field investigations, the research quantitatively analyzes the “locality – adaptation” reconstruction process of resettlement communities across the three spatial dimensions of living, production, and cultural spaces.Results1) Land cover evolution: Water storage of hydropower station inundates 37.12 km2 of land (including 21.61 km² of high-quality cultivated land), resulting in a loss of 43.68% of settlement production space. 2) Adjustment of architectural space: 65.8% of dwellings in the original villages are traditional timber-earth buildings with a tile roof, which adapt to the climate environment of concentrated rainfall and sufficient sunshine in the Jinsha River Basin. 48.7% of the resettlement sites adopt unified flat roof planning, and 51.3% realize functional optimization through self-construction or renovation, with the average renovation area reaching 230.9 m2. 3) Transformation of livelihood system: The annual compensation mechanism only restores 15.79% of the cultivated land allocation before resettlement, and the proportion of compensation income drops from 82.71% in the initial stage of relocation to 33.15% after long-term resettlement, driving the adjustment of crop structure to high value-added cash crops. 4) Cultural space reconstruction: In the context of the disappearance of traditional water transport functions, the three cultural relics reconstructed in different places show a symbolic turn. …”
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Immunomodulatory biomaterials for osteoarthritis: Targeting inflammation and enhancing cartilage regeneration
Published 2025-10-01“…Osteoarthritis (OA) is a prevalent joint disorder characterized by progressive cartilage degradation, impaired mesenchymal stem cell (MSC) function, and chronic inflammation, ultimately leading to irreversible structural damage and functional impairment. …”
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