Codesign with citizens to prevent cardiometabolic diseases in disadvantaged neighbourhoods: an interview study on needs and priorities among stakeholders in Sweden by Meena Daivadanam, Helle Mølsted Alvesson, Mats Martinell, Hedda Ottesen, Laran Matta, Jonas Idevall Hagren, Pia McAleenan

“…Additionally, the persistence of a siloed system structure of organisations and the risks associated with accessing target populations through local intermediaries added to the challenges.Conclusion This study highlights the lack of integration of organisational values and functions within and across organisations, hindering cross-sector collaboration and citizen engagement in prevention and health promotion activities. …”
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Scaffolding theory of maturation, cognition, motor performance, and motor skill acquisition: a revised and comprehensive framework for understanding motor–cognitive interactions ac... by Thomas Jürgen Klotzbier, Nadja Schott

“…For example, in aging populations, SMART COMPASS can guide tailored interventions combining cardiovascular training with task-specific motor learning to maintain executive function and reduce fall risk. …”
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Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues by Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li

“…Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. …”
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Effect of cognitive-only and cognitive-motor training on preventing falls in community-dwelling older people: protocol for the smart±step randomised controlled trial by Catherine Sherrington, Barbara Toson, Jessica Turner, Jacqueline Close, Daina L Sturnieks, Jasmine Menant, Michael Valenzuela, Kim Delbaere, Robert D Herbert, Amit Lampit, Kathryn Broadhouse, Daniel Schoene, Stephen R Lord, Daina Sturnieks, Stephen Lord, Rob Herbert, Cameron Hicks, Mayna Ratanapongleka, Natassia Smith, Carly Chaplin, Bethany Halmy, Angeliki Stivactas, Ashley Woodbury, Dinaz Parekh, Matthew Hand, Isabella Hoi Kei leung, Polly Barr, Jennifer Davis

“…This is despite good evidence of improvements in fall-related cognitive and physical functions following both intervention types. This manuscript describes the study protocol for a three-arm randomised controlled trial to evaluate the effectiveness of home-based cognitive and cognitive-motor training interventions, compared to a minimal-intervention control group, in preventing falls in older people. …”
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Potential Moderators of Physical Activity on Brain Health by Regina L. Leckie, Andrea M. Weinstein, Jennifer C. Hodzic, Kirk I. Erickson

“…Age-related cognitive decline is linked to numerous molecular, structural, and functional changes in the brain. However, physical activity is a promising method of reducing unfavorable age-related changes. …”
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Long-term Azithromycin Prophylaxis in Pediatric Respiratory Disorders: A Narrative Review and Applications in Hong Kong by Nicole Wing Hei Tung

“…Childhood chronic respiratory conditions often involve heightened and sustained airway inflammation, presenting with recurrent symptoms ultimately resulting in lung function decline and structural disease. Thus, there is a growing interest in prophylactic interventions that may improve quality of life and reduce long-term sequelae. …”
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Urban Land Use Classification Model Fusing Multimodal Deep Features by Yougui Ren, Zhiwei Xie, Shuaizhi Zhai

“…Subsequently, VGG-16 (Visual Geometry Group 16) is used to extract the image convolutional features of the block units, obtaining the raster structure deep features. Finally, the transformer is used to fuse both topological and raster structure deep features, and land use classification is completed using the softmax function. …”
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Recent advances in dermal fibroblast senescence and skin aging: unraveling mechanisms and pioneering therapeutic strategies by Li Nan, Pengchao Guo, Wang Hui, Fang Xia, Chenggang Yi

“…Aging is a multifactorial process that affects skin integrity through the progressive decline of dermal fibroblast function. Dermal fibroblasts are key regulators of extracellular matrix (ECM) composition, wound healing, and tissue homeostasis. …”
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Mechanism and Treatment of Right Ventricular Failure Due to Pulmonary Hypertension in Children by Bibhuti B. Das

“…RVF is a clinical syndrome resulting from complex structural and functional remodeling of the right heart, leading to inadequate pulmonary circulation, reduced cardiac output, and elevated venous pressure. …”
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Classification of shoulder diseases in older adult patients: a narrative review by Hyo-Jin Lee, Jong-Ho Kim

“…Future research should focus on targeted interventions, standardized diagnostic criteria, and multidisciplinary collaboration to minimize disability, optimize function, and improve overall quality of life in this growing patient population. …”
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The properties of TREM1 and its emerging role in pain-related diseases by Zhenzhen Fan, Longde Wang, Songtang Sun, Zhaoming Ge

“…This article provides an extensive review on the structural characteristics and distribution patterns, ligand, signaling pathways, inhibitors, and pathophysiological roles of TREM1 in pain disorders aiming to further elucidate its biological function and offer novel insights for clinical interventions targeting pain-related diseases.…”
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Surgical Treatment of Age-Related Cataracts: Milestones and Challenges. Literature Review by М. М. Bikbov, G. Z. Isragilova, T. R. Gilmanshin

“…The paper presents data on the impact of global trends, local territorial and social characteristics on the number of surgical interventions for cataracts. A review of key indicators of monitoring cataract surgery has been carried out, the main factors affecting the target indicators of the cataract surgery frequency on a regional scale (age structure of the population, normative indications for surgical treatment, threshold values for visual acuity indicating the need for surgical intervention, and the proportion of people in need in surgical treatment of cataracts). …”
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WDR36 Regulates Trophectoderm Differentiation During Human Preimplantation Embryonic Development Through Glycolytic Metabolism by Shiyu An, Shuyue Hou, Feifei Xu, Huanyu Yan, Wenyi Zhang, Jinfeng Xiang, Haoran Chen, Hanwen Zhang, Lingling Dong, Xiaobin Sun, Ran Huo, Yun Chen, Xi Wang, Yang Yang

“…WD repeat domain 36 (WDR36) is known to play a critical role in mouse early embryonic development, but its regulatory function in human embryogenesis is still elusive due to limited access to human embryos. …”
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Lactobacillus plantarum SAL delays aging-associated oxidative stress and gut microbiota dysbiosis in mice by Wen Dong, Yongzhi Lun, Jie Sun, Ben Liu

“…While Lactobacillus plantarum generally enhances gut microbiota structure/function, improving health and lifespan in model organisms, the in vivo effects, mechanisms, and potential anti-aging properties of the SAL strain remain unexplored. …”
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Prediction of mild cognitive impairment using blood multi-omics data by Daniel Frank Zhang, Daniel Frank Zhang, Cigdem Sevim Bayrak, Qi Zeng, Qi Zeng, Qi Zeng, Minghui Wang, Bin Zhang, Bin Zhang, Bin Zhang, Bin Zhang

“…Mild cognitive impairment (MCI) represents an initial phase of memory or other cognitive function decline and is viewed as an intermediary stage between normal aging and Alzheimer’s disease (AD), the most prevalent type of dementia. …”
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Making the connection: social networks and type 2 diabetes among Black/African American Men: mixed-methods study protocol by Tyler Prochnow, Tyler Prochnow, Tyler Prochnow, Matthew Lee Smith, Matthew Lee Smith, Matthew Lee Smith, Megan S. Patterson, Jeong-Hui Park, Ledric D. Sherman, Ledric D. Sherman

“…This comprehensive approach will provide insights into the structure and function of social networks among B/AA men with T2D, potentially informing culturally tailored interventions to improve T2D outcomes in this underserved population. …”
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Gut microbiota diversity and composition in children with autism spectrum disorder: associations with symptom severity by Qinghuang Zeng, Yisheng Hu, Leiying Xie, Xinyi Zhang, Yun Huang, Jianbin Ye, Shouan Wang, Jia Xu

“…It offers insights for exploring ASD pathogenesis and devising interventions.…”
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Bridging the gap: assessing public understanding of medical terms in Saudi arabia’s multilingual healthcare context by Ismail Memon, Abdulaziz Alarifi, Nabeel Qamar, Ahmed Aljohani, Aamir Omair, Zeeshan Feroz, Abdulmalek Mengash, Saad Al Qarni, Shahid Akhund, Abdulmohsin Alkushi

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Gut microbiome features associate with immune checkpoint inhibitor response in individuals with non-melanoma skin cancers: an exploratory study by Yujie Zhao, Jacqueline T. Ferri, James R. White, Megan D. Schollenberger, Kim Peloza, Cynthia L. Sears, Evan J. Lipson, Fyza Y. Shaikh

“…To examine the association of gut microbiota structure and function with non-melanoma skin cancer ICI outcomes, we performed 16S rRNA V1-V2 gene amplicon sequencing of 68 fecal samples collected longitudinally from individuals with basal cell carcinoma (n = 5), Merkel cell carcinoma (n = 5), or cutaneous squamous cell carcinoma (CSCC, n = 11), followed by tumor-dependent differential analyses of bacterial composition and fecal sample analysis by untargeted metabolomics. …”
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Isolation of Human Islets for Autologous Islet Transplantation in Children and Adolescents with Chronic Pancreatitis by Rita Bottino, Suzanne Bertera, Maria Grupillo, Patricia R. Melvin, Abhinav Humar, George Mazariegos, A. James Moser, R. Matthew Walsh, John Fung, Andres Gelrud, Adam Slivka, Kyle Soltys, Martin Wijkstrom, Massimo Trucco

“…Chronic pancreatitis is an inflammatory disease of the pancreas that causes permanent changes in the function and structure of the pancreas. It is most commonly a complication of cystic fibrosis or due to a genetic predisposition. …”
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