Changes of intestinal microbiome and its relationship with painful diabetic neuropathy in rats by Shuaiying Jia, Haiqi Mi, Yao Su, Yuning Liu, Zhi Ming, Jingyan Lin

“…Sequencing analysis revealed significant differences in gut microbiota composition between PDN and control rats, with altered Bacillota/Bacteroidota ratios and increased Lactobacillus abundance. Functional annotation analysis, based on the KEGG, EggNOG, and CAZy databases, indicated significant enrichment of metabolic pathways related to carbohydrate and amino acid metabolism, energy metabolism, and cell structure biogenesis in PDN rats. …”
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Exploring Proactive Career Behavior Questionnaire Psychometrics Properties: An Adaptation to Spanish Distance Undergraduate Students by Miguel Bernabé, Richard Merhi, Ana Lisbona, Francisco Palací

“…To that end, the questionnaire is administered to 934 undergraduates. The factorial structure, validity and reliability of the questionnaire are analyzed, as well as the invariance of the scale as a function of gender. …”
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Reconfiguring Realities: On the Intra-active Liminality of Bridges by Zuzana Križalkovičová

“…Analyses of Kafka’s short story The Bridge and multimedia interventions by Svetlana Volic posit the bridge as a performative space that transcends its original utilitarian function to emerge as a dynamic platform for posthumanist inquiry. …”
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Comparing the effects of physical activity and cognitive training on cognitive performance, physical fitness, and mental health in 9- to 10-year-old children: a randomized clinical... by Shanshan Wang, Jingwu Liu

“…The study found that all cognition and mental health parameters improved significantly in the PA, CT, and PA+CT groups than in the control group (p < 0.05), with the strongest effects in PA+CT.ConclusionThis study demonstrates that structured interventions administered four times each week can differentially improve physical fitness, cognition, and mental health outcomes in school-aged children. …”
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Gut microbiota’s role in the enhancement of type 2 diabetes treatment by a traditional Chinese herbal formula compared to metformin by Chengdong Xia, Liya Yue, Yinyu Wang, Cuidan Li, Guannan Ma, Yingjiao Ju, Peihan Wang, Jie Wang, Xiaoyuan Jiang, Xiaotong Wang, Fei Chen

“…Consequently, these findings suggest that CCM offers a promising therapeutic strategy for T2DM, and further provide valuable insights into potential probiotic candidates (such as Bacteroidetes spp., Akkermansia spp., and Parabacteroides spp.) and newly identified functional pathways (such as chondroitin sulfate degradation, geraniol degradation, biotin biosynthesis, colonic acid building blocks biosynthesis, and the biosynthesis of vancomycin group antibiotics) that could be targeted for therapeutic intervention.…”
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Probiotics in Sports: Modulating the Microbiome for Performance and Health by Katarzyna Moliszewska, Paweł Kukiełka, Joanna Kośka, Gabriela Łocik, Julia Mazurek, Julia Załęcka, Alicja Nowik, Kacper Dywan, Martyna Musiorska, Michał Błaszkiewicz

“…ConclusionsThe gut microbiome is a key determinant of systemic health. Targeted diet, structured physical activity, and personalized probiotic use can optimize microbiota function. …”
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The Efficacy and Mechanism of Qinghua Jianpi Recipe in Inhibiting Canceration of Colorectal Adenoma Based on Inflammatory Cancer Transformation by Ting Liu, Juping You, Qingjian Gao, Yufeng Zhang, Wei Xu, Desong Kong, Li Chen, Bao Yuan, Haibing Hua

“…And its mechanism is related to the regulation of intestinal flora structure and abundance, short-chain fatty acid metabolism, intestinal barrier function, and inflammatory pathways.…”
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Impacts of Climate Change on the Plant Water Interactions by Turyasingura, Benson, Ayiga, Natal

“…Climate change has an impact on ecosystem structure and function globally by altering the relationships between plants and soil organisms. …”
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Aesthetic Rehabilitation of Oligodontia in Primary Dentition with Adhesive Partial Denture by Marília Ferreira Correia, Marianne Nicole Nogueira, Telma Blanca Bedran, Denise Madalena Palomari Spolidorio

“…Thus, the congenitally absence of teeth may trigger a shift in the balance of the occlusion, promoting disharmony in the structures of the maxilla-mandibular system. However, some interventions are possible to be performed in these cases even in pediatric patients, to redirect growth, preventing growth deviations and reestablishing the aesthetic. …”
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Who’s Who & Whereabouts by Petter Granli, Joyce Poole

“…We describe the system’s structure, functionality, and ease of use. La surveillance des populations d’espèces menacées est essentielle à la compréhension des dangers qu’elles rencontrent et pour la gestion des interventions mises en place afin d’assurer leur survie à long terme. …”
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Protocol for a feasibility trial of digital mindfulness and cognitive-motor exercise for subclinical depression in older adults by Haifeng Zhang, Caixia Xie, Mang Zhang, Xingyu Zhang, Tao Li, Huali Wang, Xin Yu

“…Improvements are expected in depressive and anxiety symptoms, cognition, and function, along with reduced cortisol levels. MRI may reveal structural and functional changes in brain regions associated with emotional regulation and cognition. …”
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Evaluating Teaching Effectiveness and Student Performance Across Diverse Courses: An Analysis of Final Exam Scores and Teaching Techniques by Vicente E. Montano, Glenndon C. Sobrejuanite

“…Bayesian analysis confirmed that the differences are statistically significant: the first discriminant function explains 86.8% of the variation, p < 0.001; the second function explains 13.2%, p < 0.001. …”
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Protecting health facilities: design options for armed conflict and climate change disasters by Heather Groves, Adam L. Kushner, Shailvi Gupta

“…Hospital facility designs are essential to maintaining function during times of disaster. For hospitals to remain open during emergencies, their structures must resist forces from many types of hazards such as earthquakes, hurricanes, flooding, and even societal hazards, such as war. …”
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Exercise Promotes Neuroplasticity in Both Healthy and Depressed Brains: An fMRI Pilot Study by Joanne Gourgouvelis, Paul Yielder, Bernadette Murphy

“…Exercise as an ad-on treatment for MDD is a promising therapeutic strategy shown to improve mood, cognitive function, and neural structure and function. To advance our understanding of how exercise impacts neural function in MDD, we must also understand how exercise impacts healthy individuals without MDD. …”
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Risk factors associated with poor pain outcomes following primary knee replacement surgery: Analysis of data from the clinical practice research datalink, hospital episode statisti... by Hasan Raza Mohammad, Rachael Gooberman-Hill, Antonella Delmestri, John Broomfield, Rita Patel, Joerg Huber, Cesar Garriga, Christopher Eccleston, Rafael Pinedo-Villanueva, Tamer T Malak, Nigel Arden, Andrew Price, Vikki Wylde, Tim J Peters, Ashley W Blom, Andrew Judge

“…Results are presented as relative risk ratios and adjusted risk differences (ARD) by fitting a generalized linear model with a binomial error structure and log link function.<h4>Results</h4>Information was available for 4,750 patients from 2009 to 2016, with a mean age of 69, of whom 56.1% were female. 10.4% of patients had poor pain outcomes. …”
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Perinatal SSRI exposure impacts innate fear circuit activation and behavior in mice and humans by Giulia Zanni, Milenna T. van Dijk, Martha Caffrey Cagliostro, Pradyumna Sepulveda, Nicolò Pini, Ariel L. Rose, Alexander L. Kesin, Claudia Lugo-Candelas, Priscila Dib Goncalves, Alexandra S. MacKay, Kiyohito Iigaya, Praveen Kulkarni, Craig F. Ferris, Myrna M. Weissman, Ardesheer Talati, Mark S. Ansorge, Jay A. Gingrich

“…In mice and humans, early-life SSRI exposure alters the offspring’s brain structure and is associated with anxiety and depression-related behaviors beginning in puberty. …”
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Metabolomics-driven exploration of sphingosine 1-phosphate mechanisms in refractory epilepsy by Xinyu Ben, Chang Li, Jiaqi Liu, Ting Liu, Jingyi Tong, Qifu Li

“…Additional omics analyses were conducted using cellular and animal models to explore the specific functions of S1P and related metabolic pathways. Our findings demonstrated that ACER3/SphK1/S1P play protective roles in maintaining mitochondrial structure and function. …”
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Emerging Roles of GDF15 in Metabolic and Cardiovascular Diseases by Tian Tian, Monan Liu, Peter J. Little, Hans Strijdom, Jianping Weng, Suowen Xu

“…The GFRAL receptor is central to its function, mediating the anorexigenic and metabolic effects of GDF15. …”
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Autological bone marrow concentrate for the treatment of early stages of femoral head avascular necrosis (literature review) by M. A. Panin, N. V. Zagorodnii, A. V. Boiko, A. S. Petrosyan

“…According to the overwhelming number of authors, the core decompression using autologous bone marrow cells is highly effective, significantly reducing the intensity of pain syndrome and improving the function of the hip joint. The results will be more encouraging with the further development of regenerative medicine, which will provide new samples of cellular preparations for bone tissue structure restoration.…”
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Bioengineering strategies targeting angiogenesis: Innovative solutions for osteonecrosis of the femoral head by Weihong Zhu, Zhenmu Xu, Ding Zhou, Jiankun Xu, Yuchen He, Zhong Alan Li

“…This vascular deficit results in cell apoptosis, trabecular bone loss, and structural collapse of the femoral head at late stage, significantly impairing joint function. …”
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