-
561
Genome-scale metabolic modelling of human gut microbes to inform rational community design
Published 2025-12-01“…The resulting functional database indicated that DRC-degrading abilities are rare among gut microbes, suggesting that the presence or absence of specific taxa can determine the success of DRC-based interventions. …”
Get full text
Article -
562
Enhancing Critical Writing Through AI Feedback: A Randomized Control Study
Published 2025-04-01“…Using a four-week intervention comparing Qwen-powered AI feedback to traditional instructor feedback, we employed difference-in-differences (DiD) analysis and structural equation modeling to examine how technology acceptance factors influence writing outcomes. …”
Get full text
Article -
563
The mediating role of family adaptability in the relationship between insecure attachment and family functioning in patients with major depression disorder: a cross-sectional study
Published 2025-08-01“…IntroductionDepression ranks as the second leading cause of the global health burden; therefore, identification of its risk and influencing factors is essential to develop more effective multidimensional interventions. The aim of the present study was to analyze the mediating role of family adaptability (FA) on the relationship between insecure attachment (IA) and family functioning (FF) in patients with major depressive disorder (MDD), which currently remains unclear. …”
Get full text
Article -
564
Evaluating Heart Rate Variability as a Biomarker for Autonomic Function in Parkinson’s Disease Rehabilitation: A Clustering-Based Analysis of Exercise-Induced Changes
Published 2025-03-01“…The identification of response subgroups suggests the need for personalized rehabilitation strategies to optimize autonomic function. Further research is warranted to explore the long-term impact of HRV-guided rehabilitation interventions in PD management.…”
Get full text
Article -
565
Wearable Focal Muscle Vibration Device for Reducing Spasticity and Improving Upper Limb Function: Device Co-Design and Results From a Feasibility Study in People With Stroke
Published 2025-01-01“…Objective: This study set out to co-design a wearable Focal Muscle Vibration (FMV) device and test its feasibility as a rehabilitation tool to reduce spasticity and improve upper limb function in stroke population. Methods: The objective was achieved through carrying out: a) a semi-structured workshop involving chronic stroke patients, clinicians and researchers to gather systematic user feedback, b) changes to the device design based on this feedback, c) feasibility study comparing effectiveness of 40 minutes of INTERVENTION (FMV+ conventional therapy) with CONTROL (conventional therapy alone), in reducing spasticity and improving upper limb function in 10 stroke participants, d) Quantitative (Fugl Meyer Upper Limb (FMUL), Modified Ashworth (MASh), Pittsburgh Rehabilitation Participation Scale (PRPS), Recruitment Rate and Retention Rate)) and Qualitative (verbal and written feedback), measures to assess participants perception of the wearable technology and its potential as a rehabilitation tool in reducing spasticity and improving function. …”
Get full text
Article -
566
Pilot Randomised Controlled Trial of a Web-Based Intervention to Promote Healthy Eating, Physical Activity and Meaningful Social Connections Compared with Usual Care Control in Peo...
Published 2016-01-01“…Thematically analysed, semi-structured, qualitative interviews assessed acceptability of the intervention, trial design, procedures and outcome measures.…”
Get full text
Article -
567
-
568
Myths and facts about functional neurological disorders: a cross-sectional study of knowledge and awareness among medical students and healthcare professionals in Iraq
Published 2023-09-01“…Background Functional neurological disorder (FND) is a complex condition with neurological symptoms but no clear structural or biochemical explanation. …”
Get full text
Article -
569
Strength-agility and fine motor are differently associated with non-verbal intelligence in dependency to sex and age in school children: Structural equation modelling multigroup ap...
Published 2024-11-01“…While motor proficiency has been positively linked to various cognitive functions in children, its relationship with nonverbal Intelligence remains an open question. …”
Get full text
Article -
570
Understanding the role of family functioning, dietary adherence, and culture on glycemic control among adults with type 2 diabetes: A mediation and moderation analysis.
Published 2025-01-01“…Mediation and moderation analyses were conducted using Stata's structural equation model (SEM).<h4>Results</h4>Healthy family functioning, good dietary adherence and good glycemic control rates were 56.8%, 33%, and 30.5% respectively. …”
Get full text
Article -
571
Enhancing cognitive abilities through transcutaneous auricular vagus nerve stimulation: Findings from prefrontal functional connectivity analysis and virtual brain simulation
Published 2025-05-01“…Current results indicate that the efficacy of taVNS interventions for cognitive enhancement may vary according to the pre-intervention structural and functional states of individual brains. …”
Get full text
Article -
572
Structural Equation Modeling of the Mediating Role of Resilience in the Relationship between Cognitive Emotion Regulation Strategies and Psychological Well-Being of Patients with I...
Published 2024-11-01“…Introduction: Irritable bowel syndrome (IBS) is a chronic and often debilitating functional disorder characterized by disrupted gut-brain interactions. …”
Get full text
Article -
573
Intrinsic Capacity of Chinese Community-Dwelling Older Adults Using WHO Integrated Care for Older People (ICOPE) Framework: Structural Equation Model Analysis
Published 2025-06-01“…Community-based programs integrating these modifiable factors should be prioritized to promote intrinsic capacity and functional independence among Chinese community-dwelling older adults.…”
Get full text
Article -
574
Dietary resistant starch protects against post-antibiotic intestinal damage by restoring microbial homeostasis and preserving intestinal barrier function in meat duck
Published 2025-07-01“…To directly assess the effects of RS on gut microbiota and its role in improving intestinal barrier function in meat ducks, this study first established an antibiotic-induced microbial dysbiosis model, which was characterized by reduced gut microbial diversity, intestinal dysfunction, and an inflammatory outburst following antibiotic exposure. …”
Get full text
Article -
575
The Acute Effects of Non-concussive Head Impacts on Brain Microstructure, Chemistry and Function in Male Soccer Players: A Pilot Randomised Controlled Trial
Published 2025-06-01“…Blood was also sampled, and cognitive function assessed, pre-, post-, 2.5 h post-, and 24 h post-task. …”
Get full text
Article -
576
Bridging nutrition and neurology: malnutrition's role in perioperative neurocognitive disorders
Published 2025-08-01“…Studies suggest that preoperative malnutrition may heighten the risk of PND, and that preoperative nutritional diagnosis and perioperative nutritional interventions could reduce the occurrence of PND. The review discusses the definition, diagnosis, and indicators of malnutrition, as well as the mechanisms by which malnutrition leads to PND, including direct pathways such as psychological factors, abnormal neurotransmitter synthesis, and changes in brain structure and function, and indirect pathways like impaired immune function, neuroinflammation, mitochondrial dysfunction, intestinal barrier damage, disruption of the gut-brain axis, lymphatic system dysfunction, and endocrine disruption. …”
Get full text
Article -
577
Exploring purine analogues as inhibitors against Katanin, a microtubule severing enzyme using molecular modeling approach
Published 2024-12-01“…Given its central involvement in cell division and proliferation, katanin represents a promising target for therapeutic intervention, particularly in cancer treatment. Inhibiting katanin’s function could potentially hinder the uncontrolled growth of cancerous cells, making it an attractive target for novel anti-cancer therapies. …”
Get full text
Article -
578
Evaluating the functional and genomic analysis of pathogenic junctophilin-2 variants and their association with the pathogenesis of cardiomyopathy to understand their molecular imp...
Published 2024-11-01“…Mutations in JPH2 have been associated with a range of clinical phenotypes including early-onset heart failure and cardiomyopathies, a diverse group of diseases affecting heart muscle structure and function that contribute to heart failure and sudden cardiac death. …”
Get full text
Article -
579
Comparison between the motor function of school-aged children with normal birth weight and children with low birth weight: a cross-sectional study
Published 2019-06-01“…Different socio-demographic variables of the participants were studied by using a pre-structured schedule questionnaire. Gross motor function was studied by standing broad jump and vertical jump whereas fine motor function was studied by hand reaction time and speed of movement. …”
Get full text
Article -
580
Tensiomyography, functional movement screen and counter movement jump for the assessment of injury risk in sport: a systematic review of original studies of diagnostic tests
Published 2025-03-01“…The main objective of this systematic review was to compile, synthesize and integrate international research published in different scientific databases on Countermovement Jump (CMJ), Functional Movement Screen (FMS) and Tensiomyography (TMG) tests and technologies for the assessment of injury risk in sport. …”
Get full text
Article