Social Participation of Frail Older People with Functional Limitations Ageing Alone in Place in Italy, and Its Impact on Loneliness: An Urban–Rural Comparison by Maria Gabriella Melchiorre, Marco Socci, Giovanni Lamura, Sabrina Quattrini

“…The results also indicate some different nuances regarding urban and rural sites. (4) Conclusions: Despite the fact that this exploratory study did not have a representative sample of the target population, and that only general considerations can be drawn from results, these findings can offer some insights to policymakers who aim to develop adequate interventions supporting the social participation of older people with functional limitations ageing in place alone. …”
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The Relationship between Trait Impulsivity and Everyday Executive Functions among Patients with Type 2 Diabetes Mellitus: The Mediating Effect of Negative Emotions by Na Liu, Chun-Ni Heng, Yi Cui, Ling Li, Yan-Xue Guo, Qin Liu, Bao-Hua Cao, Di Wu, Yin-Ling Zhang

“…The participants completed the Sociodemographic Questionnaire, Mini-Mental State Examination (MMSE), Barratt Impulsiveness Scale-Brief (BIS-Brief), Depression Anxiety and Stress Scales with 21 items (DASS-21), and Behavior Rating Inventory of Executive Function-Adult (BRIEF-A) version. A structural equation modeling was used to verify the mediating effect of negative emotions on the relationship between trait impulsivity and EFs. …”
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ArfGAP3 Protects Mitochondrial Function and Promotes Autophagy Through Rab5a‐Mediated Signals in Ageing Skeletal Muscle by Mao Chen, Xiaoyu Huang, Bingshu Li, Ya Xiao, Liying Chen, Fangyi Zhu, Shasha Hong, Jianming Tang, Suting Li, Jie Min, Wenyi Jin, Yubiao Zhang, Lian Yang, Yang Li, Shufei Zhang, Li Hong

“…Methods Mouse models of natural ageing and D‐gal (D‐galactose)–induced ageing were subject to analyse the structure, function and pathological alterations of the PFM and the expression of ArfGAP3. …”
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Comparative effects of square-stepping and strengthening exercises on cognitive and balance functions in chronic obstructive pulmonary disease: a randomized clinical trial by Alp Özel, Eylem Tütün Yümin, Suat Konuk

“…Background Cognitive impairment and balance dysfunction are common in individuals with chronic obstructive pulmonary disease (COPD), yet targeted interventions remain limited. Square-stepping exercise (SSE), a structured multitasking intervention involving progressive, multi-directional step patterns, combines cognitive and motor challenges. …”
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Diabetes-associated sleep fragmentation impairs liver and heart function via SIRT1-dependent epigenetic modulation of NADPH oxidase 4 by Yuanfang Guo, Jie Wang, Dongmei Zhang, Yufeng Tang, Quanli Cheng, Jiahao Li, Ting Gao, Xiaohui Zhang, Guangping Lu, Mingrui Liu, Xun Guan, Xinyu Tang, Junlian Gu

“…Here, our findings revealed that sleep fragmentation (SF) displayed notable hepatic detrimental phenotypes, including steatosis and oxidative damage, along with significant abnormalities in cardiac structure and function. All these pathological changes persisted even after sleep recovery for 2 consecutive weeks or more, displaying memory properties. …”
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Longitudinal Reciprocal Effects of Physical Exercise, Executive Function, and Subjective Well-Being: A Three-Wave Random-Intercept Cross-Lagged Panel Model in Chinese Minority Coll... by Xueyan Bai, Lin Yang

“…Objective: This study investigates the longitudinal reciprocal relationships among physical exercise (PE), executive function (EF), and subjective well-being (SWB) in ethnic minority college students in China, with the aim of providing theoretical and practical guidance for their psychological and cognitive development. …”
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Targeted maximum likelihood based estimation for longitudinal mediation analysis by Wang Zeyi, Laan Lars van der, Petersen Maya, Gerds Thomas, Kvist Kajsa, Laan Mark van der

“…Causal mediation analysis with random interventions has become an area of significant interest for understanding time-varying effects with longitudinal and survival outcomes. …”
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Structural equation modeling of symptom clusters and health-related quality of life among patients with advanced colorectal cancer receiving chemotherapy in Bangkok, Thailand by Savitree Suratako, Yaowarat Matchim, Mary Quinn Griffin

“…Structural equation modeling (SEM) was used to test the model. …”
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Randomised controlled clinical trial of a structured cognitive rehabilitation in patients with attention deficit following mild traumatic brain injury: study protocol by Roshan das Nair, Nor Asiah Muhamad, Avril Drummond, Mazlina Mazlan, Norhamizan Hamzah, Vairavan Narayanan, Norlisah Ramli, Nor Atikah Mustapha, Nor Adibah Mohammad Tahir, Li Kuo Tan, Mahmoud Danaee, Sing Yau Goh

“…Objectives To measure the clinical, structural and functional changes of an individualised structured cognitive rehabilitation in mild traumatic brain injury (mTBI) population.Setting A single centre study, Malaysia.Participants Adults aged between 18 and 60 years with mTBI as a result of road traffic accident, with no previous history of head trauma, minimum of 9 years education and abnormal cognition at 3 months will be included. …”
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Bibliometric mapping of diabetes mellitus and sarcopenia research: hotspots and emerging trends by Min Wang, Qiyang Zhou, Xinyu Guo, Xiaolong Cui, Zhongquan Tang, Ting Ou, Xiaomin Zhao, Chen Liang, Peiyu Xu, Xinyu Dai, Jingqing Yao, Guozhong Ji, Yuntao Li

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Optimizing Conservative Treatment for Femoroacetabular Impingement Syndrome: A Scoping Review of Rehabilitation Strategies by Federica Giorgi, Daniela Platano, Lisa Berti, Danilo Donati, Roberto Tedeschi

“…<b>Results</b>: Both conservative rehabilitation and surgical intervention resulted in significant improvements in pain, function, and quality of life. …”
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Exploring the relationship between intrinsic capacity and social participation in healthy ageing: Evidence from Singapore by Grace Cheong, William Tov, Robin Wai Munn Choo, Micah Tan, Lay Khoon Lau, Wee Shiong Lim, Yew Yoong Ding, Paulin Tay Straughan

“…This study emphasizes the need for healthcare interventions aimed towards the promotion of healthy ageing to adopt a holistic approach that enhance IC across its five domains, ensuring both social and physical participation and functional independence of older adults.…”
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Mindful Nonreactivity, Anxiety, Depression, and Perceived Stress as Mediators of the Mindfulness Virtual Community Intervention—Pathways to Enhance Mental Health in University Stud... by Meysam Pirbaglou, Christo El Morr, Farah Ahmad, Paul Ritvo

“…MethodsMediation analysis, using structural equation modeling, was used to assess direct and indirect relationships between study group (ie, intervention or wait list control) and outcomes. …”
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Beyond clinical risk: tackling loneliness through a population health lens by Ananda Zeas-Sigüenza, Ananda Zeas-Sigüenza, Pablo Ruisoto, Pablo Ruisoto, Pablo Ruisoto, Kami Koldewyn, Ferran Muntané, Ferran Muntané, Joan Benach, Joan Benach

“…Specifically, we propose a loneliness spectrum model and a systemic intervention framework that targets structural determinants, positioning loneliness prevention as a fundamental public health strategy through nature-based and community-driven interventions.…”
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Thyroid Dysfunction and Cytological Patterns among Patients Requested for Thyroid Function Test in an Endemic Goiter Area of Gondar, North West Ethiopia by Daniel Asmelash, Kumlgn Tesfa, Belete Biadgo

“…For early diagnosis and appropriate intervention in goiter endemic areas, the thyroid function test should be closely monitored.…”
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Functional improvement by tendon transfer for residual wrist dysfunction after botulinum therapy for severe upper limb spasticity: a case report by Takatoshi Hara, Yuta Miyazaki, Daisuke Nishida, Naho Takahashi, Keiko Sone, Yuki Hara, Ayano Matsui, Masahiro Abo

“…These findings highlight the importance of tailoring treatment strategies to individual patient characteristics, particularly the presence of residual voluntary muscle activity and the absence of structural joint deformities. This case illustrates the critical role of tendon transfer surgery as a complementary intervention to overcome the limitations of conservative treatments, leading to substantial functional recovery. …”
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Cognitive flexibility is associated with the age of onset and duration among patients with type 1 diabetes by Ding Mojun, Yuan Dongling, He Jing, Zou Wenjing, Li Xia, Li Chuting, Zhu Xiongzhao

“…Longitudinal studies are needed to further understand these relationships and guide targeted interventions to preserve cognitive function.…”
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Interplay of fatty acids, insulin and exercise in vascular health by Kara C. Anderson, Jia Liu, Zhenqi Liu

“…Importantly, these effects are both functionally and structurally dependent, with saturated fatty acids as the primary culprits, while polyunsaturated fatty acids may support insulin sensitivity and endothelial function. …”
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Development of a Methodology Based on ALS Data and Diameter Distribution Simulation to Characterize Management Units at Tree Level by Jean A. Magalhães, Juan Guerra-Hernández, Diogo N. Cosenza, Susete Marques, José G. Borges, Margarida Tomé

“…MUs within a forest intervention zone in northern Portugal, the research initially assesses the suitability of two highly flexible Probability Density Functions (PDFs), Johnson’s SB and Weibull, for simulating diameter distribution in maritime pine stands in Portugal using the PINASTER database. …”
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The impact of flatfeet on the correlation between functional movement scores, balance, agility, and core muscle strength in young females: a cross-sectional study by Maryam Ghorbani, Rasoul Yaali, Hassan Sadeghi, George A. Koumantakis

“…Abstract Changes in foot structure, particularly the presence of flatfeet, have been associated with various limitations in physical performance. …”
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