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The Neuromusculoskeletal Modeling Pipeline: MATLAB-based model personalization and treatment optimization functionality for OpenSim
Published 2025-05-01“…Abstract Neuromusculoskeletal injuries including osteoarthritis, stroke, spinal cord injury, and traumatic brain injury affect roughly 19% of the U.S. adult population. Standardized interventions have produced suboptimal functional outcomes due to the unique treatment needs of each patient. …”
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362
Social capital, functional health status and quality of life among adults in rural Southwest Nigeria
Published 2025-04-01“…The association between structural social capital, functional health status, and quality of life was investigated using Structural Equation Models. …”
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363
Sociopsychological determinants of functional foods consumption in China: based on the theory of the planned behavior expansion model
Published 2025-08-01“…This research empirically validates the explanatory power of the expanded Theory of Planned Behavior (TPB) in the context of functional food consumption. The results establish a more detailed conceptual framework for understanding consumption mechanisms, while providing evidence-based strategies for market development and public health interventions.…”
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364
Angiotensin Receptor–Neprilysin Inhibition (Sacubitril/Valsartan) Reduces Structural Arterial Stiffness in Middle‐Aged Mice
Published 2024-02-01“…Arterial stiffening leads to fundamental alterations in central hemodynamics with widespread detrimental implications for organ function resulting in significant morbidity and death, and specific therapies to address the underlying age‐related structural arterial remodeling remain elusive. …”
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365
Is School Function in Children with Down Syndrome the Same as Their Normally Developing Peers? A Preliminary Study
Published 2025-03-01“…Children with DS performed significantly better in physical tasks than in cognitive-behavioral functions. The weakest cognitive-behavioral functions requiring particular rehabilitation interventions are task behavior/completion and safety.…”
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366
Addiction Memory, Family Functioning, and Depression in Illicit Drug Users: Self-Esteem as a Mediator
Published 2024-12-01“…These findings suggest that interventions targeting addiction memory and family functioning may alleviate depressive symptoms by improving self-esteem among illicit drug users.…”
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367
The Ellipsoid Zone Is a Structural Biomarker for Visual Outcomes in Diabetic Macular Edema and Macular Hole Management
Published 2025-01-01“…Objectives: The goal was to study the ellipsoid zone (EZ) as a structural biomarker for final visual outcomes after pharmacological intervention in center-involving diabetic macular edema (DME) and surgical intervention for full-thickness macular holes (FTMHs). …”
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368
The availability and functionality of medical equipment and the barriers to their use at comprehensive specialized hospitals in the Amhara region, Ethiopia
Published 2025-01-01“…Therefore, to improve healthcare service delivery, collaborative efforts and targeted interventions are essential in optimizing the availability and functionality of medical equipment at each and every health facility.…”
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369
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Effects of Dendrobium officinale Kimura & Migo flower flavonoids on cognitive function by regulating gut microbiota
Published 2025-06-01“…Dendrobium officinale Kimura & Migo flower flavonoids (DOFF) can effectively regulate the structure of intestinal microbiota, antioxidant and anti-inflammatory functions.MethodsDOFF samples were extracted by water extraction assisted ultrasonic ethanol method. …”
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371
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Effect of Aerobic Treadmill Exercise Regulating Glucose Transporter 9 on Renal Function in Hyperuricemia Rats
Published 2022-04-01“…Hematoxylin-eosin (HE) was used to stain the renal histopathological section, and the microscope (×400) was used to observe the structural changes of renal tubules and glomerulus; the peroxidase method was used to detect the renal function indexes such as uric acid (UA), creatinine (Cre) and urea nitrogen (BUN); enzyme-linked immunosorbent assay (ELISA) method was used to determine the contents of interleukin-1β (IL-1β) in serum and kidney tissues; Western blot was used to detect the expressions of Caspase-1, IL-1β and glucose transporter 9 (GLUT-9) in the kidney tissues.Results① Pathological examination results: there was not obvious pathological changes were observed in the kidney tissues of the Control group; in the Model group, the renal tissue capsule was incomplete, the glomerulus was deformed and atrophic, and the renal tubules were disordered; in the Exercise group, the number of inflammatory cell infiltration was significantly decreased, the renal tubular structure was relatively intact, and the pathological changes such as cytoplasmic vacuolation of renal tubular epithelial cells were significantly decreased. ② UA, Cre and BUN content of serum: compared with the Control group, UA, BUN and Cre content in serum of the Model group and Exercise group was significantly increased (<italic>P</italic><0.05); compared with the Model group, UA, BUN and Cre content in serum of the Exercise group were significantly decreased (<italic>P</italic><0.05). ③ Serum and kidney IL-1β content: compared with the Control group, the expression of IL-1β in serum and kidney of the Model group and the Exercise group were significantly increased (<italic>P</italic><0.05); compared with the Model group, the expression of IL-1β in serum and kidney of the Exercise group was significantly decreased (<italic>P</italic><0.05). ④ Expressions of Caspase-1, IL-1β and GLUT-9 protein: compared with the Control group, the expressions of Caspase-1, IL-1β and GLUT-9 protein in kidney tissues of the Model group and the Exercise group were significantly increased (<italic>P</italic><0.05); compared with the Model group, the expressions of Caspase-1, IL-1β, and GLUT-9 protein in kidney tissues of the Exercise group were significantly decreased (<italic>P</italic><0.05).ConclusionAerobic treadmill exercise can effectively reduce the level of uric acid and inflammatory response of hyperuricemia rats, and improve renal function, which may be related to the regulation of GLUT-9 protein expression.…”
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373
Who has sheds? Exploring practices and determinants of overnight housing for backyard poultry in rural Bangladesh to inform an intervention to limit exposure to poultry and poultry...
Published 2025-01-01“…Housing poultry separately from the dwelling overnight is a potential intervention to limit exposure to poultry. The aim of this study was to describe practices and determinants of overnight poultry housing in rural Bangladesh as formative research for an intervention to separate young children from poultry and poultry feces. …”
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374
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Factor Structure of the Brief Coping Orientation to Problems Experienced Inventory (Brief-COPE) in Chinese Nursing Students
Published 2025-01-01“…<b>Background/Objectives</b>: Coping strategies are influenced by sociocultural factors, and an understanding of how the Brief-COPE functions within the Chinese student population is important for its validity and reliability. …”
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376
An observational, multigenerational platform for health systems and population health interventions to minimise intergenerational transmission of non-communicable diseases in India...
Published 2025-04-01“…Clinical assessments include anthropometric measurements, blood samples for a wide range of NCD indicators, bone health and muscle function. The long-term data analysis plan includes longitudinal modelling, time-series analyses, structural equation modelling, multilevel modelling and sex-based analyses to investigate growth trajectories and intergenerational patterns of health risks. …”
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377
Integrating AI predictive analytics with naturopathic and yoga-based interventions in a data-driven preventive model to improve maternal mental health and pregnancy outcomes
Published 2025-07-01“…Additionally, a custom loss function integrating Cross-Entropy Loss and an F1 Score Penalty was introduced to address class imbalance and enhance model performance. …”
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378
Patient and Provider Perspectives of a Web-Based Intervention to Support Symptom Management After Radioactive Iodine Treatment for Differentiated Thyroid Cancer: Qualitative Study
Published 2025-03-01“…An additional aim included assessing features and functionalities desirable in the development of a web-based intervention to engage patients in their self-management and thyroid cancer survivorship care. …”
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379
The Structure of Stress Experiences in Patients in the Lumbar Spine Pain Syndrome during the COVID-19 Epidemic in Poland
Published 2021-09-01“…The obtained data suggest that when designing interventions supporting the mental functioning of this group of patients, consideration should be given to taking into account individual differences identified in the studies. …”
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380
Improving measurement of functional status among older adults in primary care: A pilot study.
Published 2024-01-01“…The objective of this study was to pilot test a person-centered, interprofessional intervention to improve identification and management of functional impairment among older adults in Veterans Affairs (VA) primary care practices. …”
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