The Effect of Eight Weeks Pilates Training on Functional Indicators and Postural Abnormalities in Older Men by Keyvan Hejazi, Mohammad Roki, Aref Makrami Mayvan, Azizeh Toghdori

“…However, the variables of forward head 2.22%, scoliosis 1.02%, kyphosis 4.73%, and lordosis 6.04% significantly decreased after the training intervention. Conclusion: Pilate’s training has been linked to enhanced functional indicators and a reduction in abnormalities. …”
Get full text

Addiction Severity, Social Functioning, And Life Satisfaction Of Patients Diagnosed With Substance Use Disorders by Baruah Aditi, Baruah Arunjyoti

“…Conclusion: Interventional study could be done to implement some activities, social functioning and life satisfaction of patients diagnosed with SUDs.…”
Get full text

The impact of warm-up with the volleyveilig approach on upper extremity function in female volleyball players by Adibeh Baharmast, Parisa Sedaghati, Somayeh Ahmadabadi

Get full text

Postural exercise impaction on the development of vertebral curves and functional deformity for adolescent idiopathic scoliosis by Dea Linia Romadhoni, Alinda Nur Ramadhani

“…All data were documented through structured questionnaires. Results: The findings revealed a statistically significant reduction in vertebral inclination angle following the intervention (p<0.001), indicating the effectiveness of posture correction exercises as part of scoliosis-specific rehabilitation programs. …”
Get full text

Predicting clinical outcome by indexed mitral valve tenting in functional mitral valve regurgitation by Christoph R Sinning, Maria von Stumm, Florian Dudde, Theresa Holst, Tatjana Sequeira-Gross, Jonas Pausch, Lisa Müller, Hermann Reichenspurner, E Girdauskas

Get full text

Bifurcation in the healing or fibrotic response in a network model of fibrosis: role of the initial injury structure by Ethan Israel, Joseph K. Hall, Yuqing Deng, Jason H. T. Bates, Béla Suki

“…Furthermore, we show that selectively modifying the stiffness of pivotal network regions at the time of injury can shift the network’s trajectory from fibrosis to healing, highlighting potential intervention targets. These findings suggest that the network structure of tissue injury may serve as a predictive marker for fibrosis susceptibility and provide a mechanistic basis for understanding the nonlinear progression of PF.…”
Get full text

Translation, Cultural Adaptation and Content Validity of the Persian Version of the Structured Cognitive Training Program “NEUROvitalis” by Milad Karimi, Amin Modarres Zadeh, Payam Kabiri, Hasan Ashayeri, Ahmad Rreza Khatoonabadi, Elke Kalbe

Get full text

The value of intellectual structural imbalance in the differentiation of autism spectrum disorder and attention deficit hyperactivity disorder by Dan-Yang Zhang, Qiu-Hong Wei, Bin-Yue Hu, Dan Ai, Yu Zhang, Yuan Ding, Ting Yang, Jie Chen, Li Chen, Yuan Wu, Hong-Yu Chen, Xue-Li Xiang, Qiu-Hong Mou, Ting-Yu Li

“…BackgroundThe study delves into the intricate task of differentiating intellectual structures among children diagnosed with the high-functioning Autism Spectrum Disorder (HF-ASD), Attention Deficit Hyperactivity Disorder (ADHD), or comorbidity (ASD+ADHD), aiming to assist in their clinical differentiation, with the goal of refining clinical diagnoses and developing targeted therapeutic interventions.MethodsThe study included 200 outpatients aged 6.5–13.0 years (total Intelligence Quotient (IQ) 70–130) at the Children’s Hospital of Chongqing Medical University, and categorized into HF-ASD (n=91), ADHD (n=47), and comorbidity ASD+ADHD (n=62) groups. …”
Get full text

Why might fears and worries persist after a pain education–grounded multimodal intervention for chronic back pain? A qualitative study by Rodrigo R. N. Rizzo, Benedict M. Wand, Hayley B. Leake, Edel T. O'Hagan, Adrian C. Traeger, Sylvia M. Gustin, G. Lorimer Moseley, Saurab Sharma, Aidan G. Cashin, Matthew K. Bagg, James H. McAuley, Samantha Bunzli

“…The effect of pain education (PE) on pain intensity and function diminishes after a few months in people with chronic low back pain (CLBP). …”
Get full text

The Structural Model of Happiness Based on Mindfulness with Mediator Role of Emotional Intelligence, Self-Compassion and Resilience by Mohammad Reza Tamannai far, Faezeh Taraffo

“…Pearson's correlation coefficient method and structural equation modeling were used to analyze the data. …”
Get full text

Deep Convolutional Neural Network-Based Structural Damage Localization and Quantification Using Transmissibility Data by Sergio Cofre-Martel, Philip Kobrich, Enrique Lopez Droguett, Viviana Meruane

“…Here, we propose a novel deep CNN-based approach for structural damage location and quantification, which operates on images generated from the structure’s transmissibility functions to exploit the CNNs’ image processing capabilities and to automatically extract and select relevant features to the structure’s degradation process. …”
Get full text

Distinct structural mechanisms of LGR4 modulation by Norrin and RSPOs in Wnt/β-catenin signaling by Huarui Qiao, Fangzheng Hu, Yiang Wang, Lu Wang, Siyu Zhou, Shaojue Guo, Yiwen Xu, Jianfeng Xu, Qianqian Cui, Qilun Yang, H. Eric Xu, Jianwei Zhu, Yong Geng

“…Furthermore, we developed a high-affinity nanobody that blocks both Norrin and RSPO binding to LGR4, providing a potential tool for therapeutic intervention. These findings elucidate the structural basis of LGR4’s dual signaling roles and lay the groundwork for therapeutic strategies targeting Wnt-related diseases.…”
Get full text

Feasibility and Acceptability of Using an Evidence-Based Tai Chi Intervention for Managing the Fatigue–Sleep Disturbance–Depression Symptom Cluster in Breast Cancer Patients by Li-Qun Yao, Tao Wang, Xian-Liang Liu, Jing-Yu (Benjamin) Tan

“…Many interviewees from the Tai Chi group reported perceiving favorable effects on FSDSC management, as well as overall functional health and well-being. <b>Conclusions:</b> The evidence-based Tai Chi intervention proved feasible, safe, and convenient as a non-pharmacological intervention for managing FSDSC in breast cancer patients. …”
Get full text

Virtual Life Story Club Intervention to Improve Loneliness and Apathy in Community-Dwelling Older Adults: Protocol for a Mixed Methods Feasibility Study by Chava Pollak, Helena M Blumen, Lily Zhou, Jennifer Wong, Ying Jin, Atul Bhattiprolu, Sophie Anfang, Mirnova E Ceïde

“… BackgroundReminiscence therapy is a noninvasive, nonpharmacological intervention that has been shown to improve cognition, mood, functional status, quality of life, and apathy in older adults. …”
Get full text

An integrated, multidisciplinary management team intervention to improve patient-centeredness, HIV, and maternal-child outcomes in Lesotho: formative research on participatory impl... by Laura K. Beres, Mammatli Chabela, Matseliso Masitha, Zachary Catanzarite, Vincent J. Tukei, Lynne Mofenson, Appolinaire Tiam, Lauren Greenberg, Majoalane Mokone, Ramatlapeng Thabelo, Masepeli Nchephe, Tsietso Mots’oane, Laura Guay, Amy R. Knowlton

“…The coordination, monitoring and cross-cadre communication functions of the MDTs supported implementation of other interventions, and may serve as a valuable platform for improving patient-centered care practices in similar settings and for other health services. …”
Get full text

Functional and Evolutionary Characterization of the NSP6 Protein in SARS-CoV-2 Omicron Variants by Joyhare Barbosa Souza, Samir Mansour Moraes Casseb

“…This study analyzed the NSP6 protein of the Omicron variant, focusing on conserved motifs, mutations, and residual properties to better understand its structure, function, and potential for immune evasion. …”
Get full text

Assessment of the Core Functions of Hepatitis B Surveillance System in the Southeastern Iran: a Qualitative Study by Mozhgan Mahmoodi, Abbas Yazdanpanah, Abbas Ghavam, Khodadad Sheikhzadeh

“…Results: The main studied themes were case finding, case reporting, case registration, case confirmation, data analysis, sending feedback, and implementing interventions. The results of this study showed that all of the core functions of the hepatitis B surveillance system were running in the studied counties, although they did not meet the relevant standards in some cases. …”
Get full text

Thymidine phosphorylase in nucleotide metabolism: physiological functions and its implications in tumorigenesis and anti-cancer therapy by Bo Huang, Bo Huang, Qihang Yuan, Jiaao Sun, Chao Wang, Dong Yang

“…Ongoing research on TYMP could deepen our understanding of human physiology and the pathogenesis of cancer and open new avenues for therapeutic interventions. This article provides a comprehensive review of TYMP’s structure, physiological functions, and its role in tumorigenesis and anti-tumor therapy.…”
Get full text

Exploring cerebrospinal fluid metabolites, cognitive function, and brain atrophy: Insights from Mendelian randomization by Liu Qian, Meng Ling-bing, Qi Tian-qi, Ma Ya-Qing, Liang Guo-wei

“…Disruption of cerebrospinal fluid (CSF) metabolites affects brain function and cognition, potentially altering the brain structure. …”
Get full text

Temporal evolution and factors influencing visual function and RNFL thickness in ethambutol-associated optic neuropathy by Taimin Guo, Yue Fu, Xiaoyu Xu, Xiaoning Liu, Yurong Zhang, Hui Yang

“…Abstract Purpose This study aimed to investigate the temporal evolution and influencing factors of visual function and optic nerve structure in ethambutol-associated optic neuropathy (EON). …”
Get full text