Twenty-year changes in the clinical and echocardiographic characteristics of patients with early postinfarction remodeling after primary ST-segment elevation myocardial infarction by A. M. Nikolaeva, T. R. Ryabova, A. A. Sokolov, V. V. Ryabov

“…Aim. To compare structural and functional left ventricular (LV) changes in the early period of myocardial infarction (MI) within 20 years on the basis of the Emergency Cardiology Department of the Cardiology Research Institute (Tomsk).Material and methods. …”
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Genetic variants and molecular profiling of 46,XY gonadal dysgenesis using whole-exome sequencing by Ning Zhang, Ning Zhang, Ning Zhang, Shuoming You, Shuoming You, Jingjing Guo, Jingjing Guo, Xingyu Chang, Xingyu Chang, Junjun Qiu, Junjun Qiu, Keqin Hua, Keqin Hua

“…The variants were confirmed via Sanger sequencing, and detailed functional prediction of the discovered genetic variants was conducted. …”
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Adipocytes reprogram the proteome of breast cancer cells in organotypic three-dimensional cell cultures by Karla Tovar-Hernández, Yarely M. Salinas-Vera, Ángeles Carlos-Reyes, Alejandra P. García-Hernández, Laurence A. Marchat, Gilberto Mandujano-Lázaro, Emmanuel Ríos-Castro, Andrea Velasco-Suárez, Ivonne Mendez-Gómez, Ángeles C. Tecalco-Cruz, Eloisa Ibarra-Sierra, César López-Camarillo

“…Interestingly, lipid transport proteins, including PITPNM2, ATP2C1, ABCA12, HDLBP, and APOB, showed perturbations in their expression, which were also associated with low overall survival in breast cancer patients. Functional studies showed that the knockdown of apolipoprotein B (APOB) expression in Hs578t cells reduced the size of 3D cellular structures. …”
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Understanding facilitators and barriers to adherence in home-based pulmonary rehabilitation for chronic obstructive pulmonary disease patients using the Health Belief Model: a qual... by Qiuxuan Zeng, Wenli Chen, Siyi Xu, Xu Yang, Dandan Xue, Yuhang Peng, Xiaohong Lin, Yingwen Yu, Huixin Huang, Ping Huang, Min Dong, Jiaying Li

“…BackgroundHome-based pulmonary rehabilitation (PR) is a key non-pharmacological intervention for chronic obstructive pulmonary disease (COPD), but poor adherence limits its effectiveness. …”
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The Impact of Biodex Balance on Improving Coordination and Static Balance in Patients with Diabetic Peripheral Neuropathy by Kristo Xhardo, Elona Xhardo, Mircea Bratu, Alin Pandea, Mariana Cordun, Ana-Maria Vasiliu, Dan-Eugen Costin, George Sebastian Iacob, Marjan Mihajlov, Ilie Onu, Daniel-Andrei Iordan

“…These findings support integrating the BBS into structured diabetic care programs to reduce fall risk and improve functional stability.…”
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Design and methods of an adaptive trial to test comparative effectiveness of readmission reduction approaches following infection and sepsis hospitalizations (ACCOMPLISH) by Kristin Mayes, Victor B. Talisa, Adelina Malito, Florian B. Mayr, Kelly Williams, Kalpana Char, Richard Wadas, Elizabeth Lorenzi, Kert Viele, Rana Awdish, Derek C. Angus, Chung-Chou Ho Chang, Sachin Yende

“…Secondary endpoints, such as functional status and health-related quality of life, will be measured at baseline and 90 days. …”
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Deciphering the role of metal ion transport-related genes in T2D pathogenesis and immune cell infiltration via scRNA-seq and machine learning by Zuhui Pu, Zuhui Pu, Tony Bowei Wang, Ying Lu, Ying Lu, Zijing Wu, Zijing Wu, Yuxian Chen, Ziqi Luo, Xinyu Wang, Lisha Mou, Lisha Mou

“…Additionally, we performed a detailed cell-cell communication analysis to identify significant signaling pathways in T2D.ResultsOur analysis identified 1953 DEGs between T2D and ND patients, with the Stepglm[backward] plus GBM model demonstrating high predictive accuracy and identifying 13 hub RMITRGs. Twelve protein structures were predicted using AlphaFold 3, revealing potential functional conformations. …”
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Comparative analysis of ground reaction forces and spatiotemporal gait parameters in older adults with sway-back posture and chronic low back pain: a cross-sectional study by Fatemeh Esmaeilpour, Amir Letafatkar, Mohammad Taghi Karimi, Mehdi Khaleghi, Giacomo Rossettini, Jorge Hugo Villafañe

“…Abstract Background Gait alterations associated with postural deviations are a significant factor contributing to functional limitations in older adults. Among these, sway-back posture has been linked to chronic low back pain (CLBP), defined as pain persisting for more than three months. …”
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Unravelling critical burnout syndrome in Chinese hospitals a network analysis of the Maslach burnout inventory human services survey by Mayangzong Bai, Tiantian Jing, Sisi Li, Zhiruo Zhang

“…Furthermore, the MCFA results established structural invariance for the three-factor 20-item model. …”
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Evaluation of Clinical Efficiency of Cardioprotective Therapy in Patients with Acute Myocardial Infarction by I. D. Astrakhantseva, A. S. Vorobyov, K. Yu. Nikolayev, I. A. Urvantseva

“…The combined use of atorvastatin 80 mg/day for a month from the onset of STEMI and a single intravenous injection of metoprolol tartrate (5–15 mg) in the acute phase of STEMI before PCI showed the most significant effects in the prevention of the development of structural and functional myocardial disorders and clinically severe heart failure, and also caused the minimal serum activity of cardiomarkers in the third group of patients in comparison with the first and second groups of patients without this drug combination. …”
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The implementation, use and sustainability of a clinical decision support system for medication optimisation in primary care: A qualitative evaluation. by Mark Jeffries, Nde-Eshimuni Salema, Libby Laing, Azwa Shamsuddin, Aziz Sheikh, Anthony Avery, Antony Chuter, Justin Waring, Richard N Keers

“…Engagement between stakeholders was considered important for the intervention in ensuring prescribers continued to utilise its functionality. …”
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Comparison of treatment outcomes in severe personality disorder patients with or without substance use disorders: a 36-month prospective pragmatic follow-up study by Lana F, Sanchez-Gil C, Adroher N, Perez Sola V, Feixas G, Martí-Bonany J, Torrens Melich M

“…These 28 cases were then compared to the 23 patients without SUD (PD-nSUD) in terms of psychiatric hospitalizations and psychiatric emergency room (ER) visits before and during the 6-month therapeutic intervention and every 6 months thereafter for a total of 36 months.Results: The baseline clinical characteristics correspond to a sample of PD patients (78% met DSM-IV criteria for borderline PD) with poor general functioning and a high prevalence of suicide attempts and self-harm behaviors. …”
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Construction of Clinical Predictive Models for Heart Failure Detection Using Six Different Machine Learning Algorithms: Identification of Key Clinical Prognostic Features by Qu FZ, Ding J, An XF, Peng R, He N, Liu S, Jiang X

“…Fang Zhou Qu,1 Jiang Ding,2 Xi Feng An,3 Rui Peng,4 Ni He,5 Sheng Liu,1 Xin Jiang5 1Medical School, Xizang Minzu University, Xianyang, People’s Republic of China; 2Institute of Electrical Power Systems, Graz University of Technology, Graz, Austria; 3The First Affiliated Hospital of Jinan University, Guangzhou, People’s Republic of China; 4Affiliated Nanhua Hospital, University of South China, Hengyang, People’s Republic of China; 5Department of Cardiology, Shaanxi Provincial People’s Hospital, Xi’an, People’s Republic of ChinaCorrespondence: Xin Jiang, Department of Cardiology, Shaanxi Provincial People’s Hospital, Xi’an, Shanxi Province, People’s Republic of China, Email 18560453060@163.comPurpose: Heart failure (HF) is a clinical syndrome in which structural or functional abnormalities of the heart result in impaired ventricular filling or ejection capacity. …”
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Amniotic fluid-derived stem cells: potential factories of natural and mimetic strategies for congenital malformations by Cristiane S. R. Fonteles, Julia Enterria-Rosales, Ying Lin, John W. Steele, Ramiro A. Villarreal-Leal, Jing Xiao, Daniel I. Idowu, Beck Burgelin, Bogdan J. Wlodarczyk, Richard H. Finnell, Bruna Corradetti

“…A physicochemical, structural, and molecular comparison was conducted with exosomes (EXOs) released from the same batch of cells. …”
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<i>PRKAG2</i> Syndrome: Clinical Features, Imaging Findings and Cardiac Events by Maria Sudomir, Przemysław Chmielewski, Grażyna Truszkowska, Mariusz Kłopotowski, Mateusz Śpiewak, Marta Legatowicz-Koprowska, Monika Gawor-Prokopczyk, Justyna Szczygieł, Joanna Zakrzewska-Koperska, Mariusz Kruk, Jolanta Krzysztoń-Russjan, Jacek Grzybowski, Rafał Płoski, Zofia T. Bilińska

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Landscape Analysis and Assessment of Ecosystem Stability Based on Land Use and Multitemporal Remote Sensing: A Case Study of the Zhungeer Open-Pit Coal Mining Area by Yinli Bi, Tao Liu, Yanru Pei, Xiao Wang, Xinpeng Du

“…Following rehabilitation efforts, the landscape patch density, landscape separation, and landscape fragmentation in the Zhungeer open-pit coal mining area exhibited a declining trend, leading to a more uniform distribution of landscape patches and improved structural balance. By 2020, the adaptability index had risen to 0.35836, achieving 93.69% of the restoration level observed prior to mining operations in 1985, thus indicating an improvement in ecosystem stability and the restoration of ecological functions, although rehabilitation efforts display a temporal lag of 10 to 15 years. …”
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End-to-End Stroke Imaging Analysis Using Effective Connectivity and Interpretable Artificial Intelligence by Wojciech Ciezobka, Joan Falco-Roget, Cemal Koba, Alessandro Crimi

“…Stroke is one of the leading causes of mortality and morbidity worldwide, and it demands precise diagnostic tools for timely intervention and improved patient outcomes. Neuroimaging data, with their rich structural and functional information, provide a fertile ground for biomarker discovery. …”
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Prevención del riesgo de caída en adultos mayores con programa Kunte durante confinamiento por COVID-19 (Prevention older adults fall risk with Kunte program during COVID-19 confi... by Manuel Villarroel Cerda, Matías Pozo Núñez, Cristián Díaz Escobar, Víctor Patricio Díaz Narváez

“…Conclusion: The application of the Kunte program showed significantly positive results when assessing dynamic body balance and gait, through functional tests related to fall risk in older adults, in this case with home confinement during the COVID-19 pandemic. …”
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KiKli Fit: Investigating the Implementation of a Physical Activity Program in Pediatric Cancer by Lars Rehbein, Ann Christin Schneider, Christina Hillebrech, Christina Schindera, Amika Singh, Katharina Eva, Valentin Benzing

“…The mediational role of executive functions for the relationship between motor ability and academic performance in pediatric cancer survivors. …”
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THE IMMUNOCOMPETENCE OF THE LYMPHOCYTIC POOL OF PERIPHERAL BLOOD IN ACUTE PURULENT LYMPHADENITIS IN CHILDREN by P.I. Tkachenko, S.O. Bilokon, N.M. Lokhmatova, O.B. Dolenko, K.Yu. Rezvina, Yu.V. Popelo

“… The substantial prevalence of different nosological forms of lymphadenitis in children is due to morpho-functional immaturity and age-related features of the structural components of the lymph node. …”
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