The Role of Circulating Biomarkers in Patients with Coronary Microvascular Disease by Rossella Quarta, Giovanni Martino, Letizia Rosa Romano, Giovanni Lopes, Francesco Fabio Greco, Carmen Anna Maria Spaccarotella, Ciro Indolfi, Antonio Curcio, Alberto Polimeni

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Validation of a Finite Element Simulation for Predicting Individual Knee Joint Kinematics by Elin Theilen, Anna Rorich, Thomas Lange, Sebastian Bendak, Cora Huber, Hagen Schmal, Kaywan Izadpanah, Joachim Georgii

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Physiotherapy in Chronic Hemodialysis Patients. Recommendations of the Expert Committee of the Rehabilitation Section at the Polish Society of Nephrology by Wioletta Dziubek, Katarzyna Chojak-Fijałka, Tomasz Gołębiowski, Łukasz Rogowski, Katarzyna Bulińska, Urszula Chrabota, Weronika Pawlaczyk, Kazimierz Ciechanowski, Mariusz Kusztal

“…Recently, measures have been initiated to improve quality of life among patients, which is largely influenced by physical functioning, the ability to undertake physical activity and functional independence. …”
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Innovative strategies for bone organoid: Synergistic application and exploration of advanced technologies by Xu Lou, Qirong Zhou, Zhenglin Dong, Long Bai, Jiacan Su, Hua Yue

“…While 3D bioprinting enhances spatial precision and structural complexity, artificial intelligence accelerates organoid optimization through data-driven approaches. …”
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Participation, promotion, and practices of the Indigenous Peoples Education (IPEd)- implementing schools in localizing sustainable development goals by Ernesto L. Bastida, Jr., Robbie Jan Vincent T. Buelo, Fatima G. Tabia, Rudy Bhonne R. De Lara, Jerbert M. Abargos, Catherine S. Oliquino

“…Participants also highlighted the relevance of reading intervention programs to make learners functionally literate. …”
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Investigation of the Relationship Between Self‐Consciousness and Autobiographic Memory in Individuals with Autism Spectrum Disorders with LiveCam and fNIRS by Yesim Unveren, Mevhibe Saricaoglu, Ece Zeynep Karakulak, Lütfü Hanoğlu

“…This study investigates the relationship between self‐consciousness, autobiographical memory, and associated neurobiological structures in ASD. Methods There were two groups: autism (N = 4) and a control group without autism symptoms (n = 8), which underwent a 2‐day LiveCam camera recording and subsequent functional near‐infrared spectroscopy (fNIRS) tasks with familiar (“old”) and unfamiliar (“new”) images. …”
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Volatile Organic Compounds in Biological Matrices as a Sensitive Weapon in Cancer Diagnosis by Arya Ghosh, Varnita Karmakar, Anroop B. Nair, Shery Jacob, Pottathil Shinu, Bandar Aldhubiab, Rashed M. Almuqbil, Bapi Gorain

“…This review provides an in-depth exploration of the structural, functional, and signaling mechanisms underlying odorant sensitivities and chemical odor detection in the excretory products of cancer patients, addressing current challenges in VOC-based cancer diagnostics and innovative strategies for advancement while also envisioning the transformative role of artificial olfactory systems in the future of cancer detection. …”
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An Update on DOTA-Peptides PET Imaging and Potential Advancements of Radioligand Therapy in Intracranial Meningiomas by Viviana Benfante, Ignazio Gaspare Vetrano, Muhammad Ali, Pierpaolo Purpura, Cesare Gagliardo, Paola Feraco, Costanza Longo, Tommaso Vincenzo Bartolotta, Patrizia Toia, Oriana Calisto, Albert Comelli, Massimo Midiri, Pierpaolo Alongi

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Chronic Abdominal Discomfort Syndrome (CADS): A Narrative Review of Treatment Strategies by Gupta M, Patil AS, Staats P, Schatman ME, Kalia H, Sayed D, Soin A, Baranidharan G, Kapural L, Chitneni A, Verrills P, Diwan S, Abd-Elsayed AA, Deer TR

“…Ultimately, this paper advocates for a structured approach to CADS treatment, incorporating both emerging and established therapeutic options.Keywords: chronic abdominal pain, abdominal discomfort, abdominal pain treatment…”
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Monitoring the effectiveness of the natural anticoagulant sulodexide in pregnant women with autoimmune hyperthyroidism on the background of hyperhomocysteinemia by A.Yu. Scherbakov, Т. А. Mіelikova

“…Among the factors that affect hemostasis, thyroid hormones occupy a special place, they are able to influence not only the functional activity of platelets, but also adjust the intensity of the plasma and tissue fibrinolysis. …”
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Diminished AdipoR1/APPL1 Interaction Mediates Reduced Cardioprotective Actions of Adiponectin against Myocardial Ischemia/Reperfusion Injury in Type-2 Diabetic Mice by Chao Ren, Wei Yi, Bo Jiang, Erhe Gao, Jiali Liang, Bo Zhang, Zhe Yang, Dezhi Zheng, Yong Zhang

“…APPL1 is a signaling protein with multiple functional structural domains and plays an important role in the APN signaling pathway. …”
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Design of a clinical balance tool for fall risk assessments: A development and usability study. by Jennifer Hornung Garvin, Virginia M Yazzie, Natalie A Katsuyama, Truman Rudloff, Lise C Worthen-Chaudhari, Ajit M W Chaudhari

“…Clinicians evaluated an initial QuPI prototype and completed a semi-structured interview to determine critical functionality, inform design, and assess usability. …”
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Patient acceptability of intravitreal complement inhibitors in geographic atrophy (GA): protocol for a UK-based cross-sectional study by David P Crabb, Deanna J Taylor, Christiana Dinah, Mandeep Sekhon, Jamie Enoch, Arevik Ghulakhszian

“…The correlation between acceptability and functional and structural biomarkers of GA will be established. …”
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Healthcare professionals’ perspectives on artificial intelligence (AI)-based mobile applications (apps) for diabetes education and behavioural management by Phei-Ching Lim, Yung-Wey Chong, Qiu-Ting Chie, Hadzliana Zainal, Kok-Lim Alvin Yau, Soo-Huat Teoh

“…Methods Qualitative study using semi-structured interviews with 19 HCPs across Malaysia. …”
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Predicting depression in healthy young adults: A machine learning approach using longitudinal neuroimaging data by Ailing Zhang, Haobo Zhang

“…This study aimed to develop predictive models for depression in young adults using machine learning (ML) techniques and longitudinal data from the Beck Depression Inventory, structural MRI (sMRI), and resting-state functional MRI (rs-fMRI). …”
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Extensive thoracic vertebral and chest wall metastases as the initial presentation of breast cancer: a case report and literature review by Yergen N. Kenzhegulov, Daniyar K. Zhamoldin, Victor G. Aleinikov, Talgat T. Kerimbayev, Berik Zhetpisbaev, Serik Akshulakov

“…Metastatic involvement of the bones remains the most common form of distant metastasis in breast cancer, largely due to the anatomical and functional characteristics of the thoracic spine, ribs, and sternum. …”
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Enhancing locally employed doctor support and integration: a QIP on a buddy programme at Russells Hall Hospital by Sumaira Malik, Tamar Saeed, Shifa Puri, Sidra Shah, Ayesha Farooq

“…The responses were collected and analysed to determine the effectiveness of the intervention. Results and discussion: The implementation of the Buddy Programme led to significant improvements across multiple areas. …”
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Physiological Mechanisms Driving Microcirculatory Enhancement: the Impact of Physical Activity by Jianyu Li, Guochun Liu, Dong Zhang, Keying Zhang, Chunmei Cao

“…Physical activity also ameliorates inflammation markers and oxidative stress levels, upregulates the expression of silent information regulator 2 homolog 3, genes for hypoxia-inducible factors under hypoxic conditions, and induces favorable changes in multiple hemodynamic and hemorheological parameters. These structural and functional adaptations optimize myocardial blood flow regulation during exercise and improve both oxygen transport and utilization capacity, which are beneficial for the rehabilitation of chronic disease patients. …”
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Clinical outcomes and anti-inflammatory mechanisms predict maximum heart rate improvement after physical activity training in individuals with psychiatric disorders and comorbid ob... by Pau Soldevila-Matías, Joan Vicent Sánchez-Ortí, Patricia Correa-Ghisays, Vicent Balanzá-Martínez, Gabriel Selva-Vera, Roberto Sanchis-Sanchis, Néstor Iglesias-García, Manuel Monfort-Pañego, Pilar Tomás-Martínez, Víctor M Victor, Benedicto Crespo-Facorro, Constanza San Martin Valenzuela, José Antonio Climent-Sánchez, Rosana Corral-Márquez, Inmaculada Fuentes-Durá, Rafael Tabarés-Seisdedos

“…<h4>Methods</h4>Patients with major depressive disorder, bipolar disorder and, schizophrenia and with comorbid obesity (n = 29) were assigned to a 12-week structured physical exercise program. Peripheral blood biomarkers of inflammation, oxidative stress, vascular mechanisms, and metabolic activity, as well as neurocognitive and functional performance were assessed twice, before and after intervention. …”
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An Unusual Congenital Heart Disease: Giant Left Atrial Appendage by Julio C. Sauza-Sosa, Erika L. De la Cruz-Reyna, Carlos N. Velazquez-Gutierrez

“…Cardiac magnetic resonance corroborated the huge left atrial appendage (Figure 1B). No other structural or functional heart abnormalities were diagnosed. …”
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