Exploring Early Mobilization Practices in Adult Intensive Care Units in Jordan: A Cross-Sectional Survey by Wshah A, Obaidat S, Shallan AI, Muhsen A, Bin Sheeha B, Alkasassbeh A, Wshah S, Al Hadidi ARB, Altaim TA, Sawafta B, Alqallab S

“…Adnan Wshah,1 Sakher Obaidat,1 Amjad I Shallan,1 Ahmad Muhsen,1 Bodor Bin Sheeha,2 Asmaa Alkasassbeh,3 Shadi Wshah,4 Abdel Razzaq Bassam Al Hadidi,5 Thamer A Altaim,1 Batul Sawafta,1 Salsabeel Alqallab6 1Department of Physical Therapy, Faculty of Applied Medical Sciences, The Hashemite University, Zarqa, Jordan; 2Department of Rehabilitation Sciences, College of Health and Rehabilitation Sciences, Princess Nourah Bint Abdulrahman University, Riyadh, Saudi Arabia; 3Physiotherapy Department, Faculty of Allied Medical Sciences, Isra University, Amman, Jordan; 4Physical Therapy Department, Jordanian Royal Medical Services, Amman, Jordan; 5Department of Physical Therapy, School of Rehabilitation Sciences, The University of Jordan, Amman, Jordan; 6Al Patrawi Physiotherapy Center, Zarqa, JordanCorrespondence: Adnan Wshah, Department of Physical Therapy, Faculty of Applied Medical Sciences, The Hashemite University, P.O box 330127, Zarqa, 13133, Jordan, Email adnan.wshah@hu.edu.joBackground: Prolonged immobilization in critically ill patients in the intensive care unit (ICU) is associated with adverse health outcomes, such as ICU-acquired weakness (ICU-AW), pressure ulcers, and decreased cardiopulmonary function. Early mobilization has been shown to be an important intervention to mitigate these effects; however, there is limited information regarding its implementation in ICUs in Jordan. …”
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Left ventricle myocardial remodeling following septal myectomy in patients with hypertrophic obstructive cardiomyopathy by Guanyu Lu, Liqi Cao, Jiehao Ou, Xinyi Luo, Wei Zhu, Zhicheng Du, Jian Liu, Yuelong Yang, Xinyue Zhang, Peijian Wei, Hongxiang Wu, Huiming Guo, Hui Liu

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Research on knowledge, attitude and practice (KAP) regarding dengue infection: a community-based study in rural Cox's Bazar by Saima Bibi

“…Face-to-face interviews were performed using a pretested and semi-structured questionnaire. Problem: DI poses a serious threat to public health, especially in tropical and subtropical areas where the dengue virus vector, the Aedes aegypti mosquito, is abundant.1,2 Bangladesh experienced its major dengue outbreak in 2019, with 100,000 cases and 120 deaths, followed by the second-largest outbreak in 2022, with 60,078 cases and 266 deaths.3,4 Assessment of problem and analysis of its causes: Bangladesh is severely affected by DI, largely due to factors including tropical climate, a dense population, unplanned urbanisation, inadequate vector control and low-literacy rates.5,6DI can cause mild fever to severe conditions, such as haemorrhagic fever, dengue shock syndrome, respiratory symptoms, gastrointestinal disturbance, low platelet count and deranged liver function tests. …”
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Sex-dependent efficacy of sphingosine-1-phosphate receptor agonist FTY720 in mitigating Huntington’s disease by Jingyun Wu, Irene Santos-Garcia, Ivan Eiriz, Thomas Brüning, Aleš Kvasnička, David Friedecký, Tuula A. Nyman, Jens Pahnke

“…Different motor behavior and physiological parameters were assessed throughout the study.The findings revealed that FTY rescued disease-related body weight loss in a sex-dependent manner, indicating its potential to regulate metabolic disturbances and to counteract neurodegenerative processes in HD. FTY intervention also rescued testicular atrophy, restored testis tissue structure in male mice suggesting a broader impact on peripheral tissues affected by huntingtin pathology. …”
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THE REGENERATIVE POTENTIAL OF BONE TISSUE IN PATIENTS WITH GENERALIZED PERIODONTITIS STAGE II, II-III AND ANALYSIS OF IT`S ROLE DURING SURGICAL OPERATIONS ON PERIODONTAL TISSUES by G.F. Biloklytska, L.M. Panchenko, I.E. Braun

“…The complicity of periodontal tissues structure and their anatomical connections during functioning determine the main problems in reaching aimed regeneration using modern methods [3,4,10,11,13-16]. …”
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Health perceptions of older individuals on the cognitive benefits of a multicomponent green physical activity program: A qualitative exploration in the Southwest Region of Bahia, B... by Carolina Rego Chaves Dias, Saulo Vasconcelos Rocha, Milena Fernandez Dias, Bruno Morbeck de Queiroz, Natália Nascimento Silva, Ariani França Conceição, Bruna Maria Palotino-Ferreira, Sonia Brito-Costa, Sofia de Lurdes Rosas da Silva, Clarice Alves dos Santos, Lélia Renata Carneiro Vasconcelos, Guilherme Eustáquio Furtado

“…Background and aims: A multicomponent exercise program (MEP) is a tailored, physical activity-based intervention that incorporates several exercise modalities to improve physical function and reduce negative health consequences, such as cognitive decline. …”
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Gene therapy prevents onset of mitochondrial cardiomyopathy in neonatal mice with Ndufs6 deficiency by Xiaoxian Zhang, Li Huang, Cheng Li, Jinjuan Yang, Fuyu Duan, Qiang Su, Yuelin Zhang, Meng Kou, Xiaoya Zhou, Liyan Guo, Shaoxiang Chen, Yongxia Niu, Ziyue Li, Sihua Ou, Min Zhang, Kenneth King-Yip Cheng, Jianlong Wu, Xiang Xu, Qizhou Lian

“…Additionally, AAV9-hNdufs6 gene therapy initiated at an early stage increased Ndufs6 expression in cardiac tissue, preserved mitochondrial structure and function, prevented cardiomyocyte fibrosis through modulation of the AMPK/Drp1 signaling pathway. …”
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Exosomes Derived From Human Mesenchymal Stem Cells Mitigate Follicular Interstitial Cell Ferroptosis via the miR-26a-5p/PTEN/GPX4 Axis in Rats with Chemotherapy-Induced Premature O... by Chen J, Huo X, Qian M, Xue Q, He Y, Xu P, Wang Y, Tang X, Luo Q, Bao H, Xiong Y

“…The expression changes of PTEN, Nrf2, and GPX4, which are associated with ferroptosis, were analyzed using immunofluorescence, Western blot, and quantitative reverse-transcription polymerase chain reaction.Results: hUCMSC-Exo intervention can significantly repair the ovarian tissue structure and functional abnormalities in the model rats, especially ferroptosis. …”
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Development of the Psychosocial Rehabilitation Web Application (Psychosocial Rehab App) by Fagner Alfredo Ardisson Cirino Campos, José Carlos Sánches García, Gabriel Lamarca Galdino da Silva, João Antônio Lemos Araújo, Ines Farfán Ulloa, Edilson Carlos Caritá, Fabio Biasotto Feitosa, Marciana Fernandes Moll, Tomás Daniel Menendez Rodriguez, Carla Aparecida Arena Ventura

“…<b>Results:</b> The web app “Psychosocial Rehabilitation Application” displays a home screen for registration and other screens structured into the stages of the psychosocial rehabilitation project (assessment, diagnosis, goals, intervention, agreements, and re-assessment). …”
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Investigating the dynamics of intracranial pressure and cerebral autoregulation during extracorporeal cardiopulmonary resuscitation using a porcine model by Tito Porras, Mingfeng Cao, Jessica Briscoe, Jin Kook Kang, Ifeanyi David Chinedozi, Zachary Darby, Shivalika Khanduja, Anastasios Bezerianos, Nitish Thakor, Glenn Whitman, Debraj Mukherjee, Steve Keller, Sung-Min Cho

“…Background: Extracorporeal cardiopulmonary resuscitation (ECPR) has emerged as a promising intervention for refractory cardiac arrest, with potential benefits in survival and neurological outcomes. …”
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Los valores del cuerpo en los jóvenes. ¿Sin valores o nueva valorización? (Body values in teenagers. No values or new valorization?)) by Lorena Velasco Santos, José Luis Pastor Pradillo, David Blanco Alcántara, Alfredo Jiménez Eguizábal

“…All this, generally speaking, supports the perspective described by the literature about the postmodern body and its great value as an organic structure to the detriment of its human function, impacting on various fields that require intervention. …”
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Effects of intermittent theta burst stimulation (iTBS) on appetite change and body weight in inpatients with schizophrenia in China: study protocol for a randomised controlled tria... by Jun Yang, Jing Huang, Jin Yang, Yue Qin, Renrong Wu, Jieyu Liu, Baoyan Xu, Haiyu Chen, Tianxiang Zou, Ziwei Teng, Tengteng Zhang, Yuhan Su, Zaiwen Dong, Chong Yang

“…MRI examination will be conducted to detect brain structure, perfusion and functional connectivity. Data analysis will be conducted in a modified intention-to-treat population. …”
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Polyphenols, Alkaloids, and Terpenoids Against Neurodegeneration: Evaluating the Neuroprotective Effects of Phytocompounds Through a Comprehensive Review of the Current Evidence by Enzo Pereira de Lima, Lucas Fornari Laurindo, Vitor Cavallari Strozze Catharin, Rosa Direito, Masaru Tanaka, Iris Jasmin Santos German, Caroline Barbalho Lamas, Elen Landgraf Guiguer, Adriano Cressoni Araújo, Adriana Maria Ragassi Fiorini, Sandra Maria Barbalho

“…Neurodegenerative diseases comprise a group of chronic, usually age-related, disorders characterized by progressive neuronal loss, deformation of neuronal structure, or loss of neuronal function, leading to a substantially reduced quality of life. …”
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Pulsed Low-Intensity Focused Ultrasound (LIFU) Activation of Ovarian Follicles by Yan Xiao, Lixia Yang, Yicong Wang, Yu Wang, Yuning Chen, Wenhan Lu, Zhenle Pei, Ruonan Zhang, Yao Ye, Xiaowei Ji, Suying Liu, Xi Dong, Yonghua Xu, Yi Feng

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ANALYSIS OF THE GINGIVAL RECESSION PREVALENCE AMONG DENTAL PATIENTS CONSIDERING ASSOCIATED AGE-RELATED, IATROGENIC AND PATHOLOGICAL CHANGES OF DENTAL STATUS by O.A. Krasnokutskyy, P.A. Hasiuk, M.Y. Goncharuk-Khomyn

“…Among all diagnosed recessions cases that were observed among patients of different age subgroups, 13,71±6,72% were associated with periodontitis pathology, 5,04±2,98% with overcrowding, 7,80±3,84% with signs of pathological attrition, 9,06±2,13% with non-carious cervical dental lesions, 7,85±1,60% with carious lesions of enamel and dentin, 7,97±1,83% with parafunctional activity and/or traumatic occlusion pattern, 7,85±4,26% with the fact of orthodontic intervention, 9,75±2,44% with existing problematic restorations, 8,16±1.62% with anomalies of teeth position, 7,72±0,74% with inadequate oral hygiene condition, 5,25±0,90% with bad habits that were identified during anamnesis collection, 5,28±2,60% with anomalies of mucous bundles attachment, while in 4,55±4,18% of the cases diagnosed recessions were not clinically associated with functional or structural dental status disorders. …”
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Case report: Endolymphatic sac tumor with blurred vision by Ke Yuan, Weijian Luo, Weijian Luo, Weijian Luo, Weijian Luo, Jia Chen, Jia Chen, Jia Chen, Jia Chen, Quanzhou Peng, Quanzhou Peng, Quanzhou Peng, Xiaoguang Tong, Xiaoguang Tong, Xiaoguang Tong, Xiaoguang Tong, Xiaoguang Tong, Jiliang Hu, Jiliang Hu, Jiliang Hu, Jiliang Hu

“…It is currently believed that prompt surgical intervention is recommended for endolymphatic sac tumors upon diagnosis. …”
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Muscarinic receptor agonists and positive allosteric modulators in animal models of psychosis: protocol for a systematic review and meta-analysis [version 2; peer review: 1 approve... by Spyridon Siafis, Johannes Schneider-Thoma, Alexandra Bannach-Brown, Oliver D. Howes, Virginia Chiocchia, Ulf Tölch, Natascha I. Drude, Sabine M. Hölter, Andrea de Bartolomeis, Anthony C. Vernon, Georgia Salanti, Sridhar Natesan, Stefan Leucht, Irene Bighelli, Sameer Jauhar, Ioannis Mantas, Josef Priller, Francesca Tinsdeall, Wulf-Peter Hansen, Fiona J. Ramage, Nobuyuki Nomura, Malcolm R. Macleod

“…We will examine other behavioural readouts of relevance for psychosis as secondary outcomes, such as social interaction and cognitive function. We will synthesize the data using multi-level meta-analysis with a predefined random-effects structure, considering the non-independence of the data. …”
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Optimized lipid nanoparticles enable effective CRISPR/Cas9-mediated gene editing in dendritic cells for enhanced immunotherapy by Kuirong Mao, Huizhu Tan, Xiuxiu Cong, Ji Liu, Yanbao Xin, Jialiang Wang, Meng Guan, Jiaxuan Li, Ge Zhu, Xiandi Meng, Guojiao Lin, Haorui Wang, Jing Han, Ming Wang, Yong-Guang Yang, Tianmeng Sun

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Multimodal versus non-contrast computed tomography for assessment of acute ischaemic stroke: the PRACTISE RCT by Keith W Muir, Salwa El Tawil, Alex McConnachie, Alicia Murray, Ian Ford, Grant Mair, Joanna Wardlaw

“…Treatment decision and delivery times, early neurological recovery and day 90 functional outcomes did not differ significantly between groups. …”
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Electroacupuncture posttreatment attenuates the inflammatory injury in rats after MIRI through PPARγ/NF-κb pathway by Xinxue Jiang, Xinxue Jiang, Chuchu Shen, Chuchu Shen, Xing Li, Xing Li, Xuefeng Xia, Xuefeng Xia, Senlei Xu, Hongru Zhang

“…The morphology and structure of myocardial tissues were examined using HE staining. …”
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