Integrating an exercise program into opioid agonist therapy: a pilot study on feasibility, fitness improvements, and participation challenges by Einar Furulund, Siv-Elin Leirvåg Carlsen, Silvia Eiken Alpers, Jørn Henrik Vold, Karl Trygve Druckrey-Fiskaaen, Tesfaye Madebo, Sindre M. Dyrstad, Torgeir Gilje Lid, Lars Thore Fadnes

“…Changes in aerobic fitness (4-minut step test), psychological distress (10-item Hopkins Symptom Checklist, SCL-10), fatigue (3-items Fatigue Severity Scale, FSS-3), lung function (spirometry), and respiratory symptoms (modified Medical Research Council Dyspnea Scale, mMRC) were assessed, while qualitative interviews provided insights into intervention feasibility. …”
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Systematic phenotype and genotype characterization of Moebius syndrome by Bryn D. Webb, Julie A. Jurgens, Narisu Narisu, Zhongyang Zhang, Brenda J. Barry, Carol Van Ryzin, Lori L. Bonnycastle, Wai-Man Chan, Tingfen Yan, Silvio Alessandro Di Gioia, Amy J. Swift, Sarah E. MacKinnon, Darren T. Oystreck, Janet C. Rucker, Tamiesha Frempong, Mary C. Whitman, Edmond J. FitzGibbon, Janice S. Lee, Ke Hao, Caroline Andrews, Monica Erazo, Flavia M. Facio, Sherin Shaaban, Thomas P. Naidich, Peter S. Chines, Tanya J. Lehky, Camilo Toro, Andrea L. Gropman, John A. Butman, Christopher K. Zalewski, Carmen C. Brewer, Audrey Thurm, Joseph Snow, Scott M. Paul, Brian P. Brooks, Carlo Pierpaoli, Caroline D. Robson, David G. Hunter, Francis S. Collins, Ethylin Wang Jabs, Elizabeth C. Engle, Irini Manoli

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A rare case of ectopic pituitary adenoma originating from the third ventricle floor: Surgical approach and outcomes by Guive Sharifi, Elham Paraandavaji, Shahin Naghizadeh, Yalda Nilipour, Mohammad Ali Kazemi, Mahbube Ebrahimpur, Ali Jafari, Farzad Taghizadeh-Hesary

“…Surgical intervention resulted in complete tumor resection without complications, leading to improved visual and endocrine function postoperatively. …”
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Implementing an online-delivered exercise program for childhood cancer survivors: A hybrid effectiveness-implementation protocol for the MERRIER studyKey points by David Mizrahi, Alexandra Martiniuk, Laurence Hibbert, Dinisha Govender, Tora Sibbald, Richard Mitchell, Natalia Millard, Lauren Ha, Damian Ragusa, Kylie Brown, Ben Smith

“…The RE-AIM framework will assess reach (e.g. recruitment rate), effectiveness (e.g. physical activity levels), adoption (e.g. qualitative interviews), implementation (e.g. exercise adherence), and maintenance (e.g. self-efficacy at follow-up). Physical function and patient-reported outcomes will be assessed at baseline (T0), post-intervention (T1; week 12) and follow-up (T2, week 24). …”
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THE IMMUNOCOMPETENCE OF THE LYMPHOCYTIC POOL OF PERIPHERAL BLOOD IN ACUTE PURULENT LYMPHADENITIS IN CHILDREN by P.I. Tkachenko, S.O. Bilokon, N.M. Lokhmatova, O.B. Dolenko, K.Yu. Rezvina, Yu.V. Popelo

“… The substantial prevalence of different nosological forms of lymphadenitis in children is due to morpho-functional immaturity and age-related features of the structural components of the lymph node. …”
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A study on the relationship between depression, treatment side effects, and marital quality in cervical cancer patients undergoing radiotherapy and chemotherapy (宫颈癌放化疗患者抑郁与治疗副反应和婚... by LI Yuhuan (李玉环), ZENG Ya (曾娅), XING Yuzhen (邢育珍)

“…Objective To explore the relationship between depression and treatment side effects and marital quality in patients undergoing radiotherapy and or chemotherapy for cervical cancer, as well as the moderating role of neurotic personality and quality of life in this relationship, in order to provide a theoretical basis for the prevention of and intervention in patients' depression. Methods The Patient-Reported Outcome Version of the Common Terminology Criteria for Adverse Events (PRO-CTCAE), the Functional Assessment of Cervical Cancer Therapy Scale (FACT-Cx), the 9-entry Patient Health Questionnaire (PHQ-9), the Big Five personality neuroticism subscale (NEO-FFIN), and the short version of the Marital Adjustment and Prediction Scale (Locke-Wallace) were used to conduct a cross-sectional survey of 1053 cervical cancer patients. …”
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Reversing cardiac hypertrophy and heart failure using a cardiac targeting peptide linked to miRNA106a by Ming Lu, Siqi Cai, Kyle Korolowicz, Claire Deng, Kaan Taskintuna, Gerard Ahern, Raymond B. Yurko, Kazi R. Islam, Bryn Schoonover, Jack B. Lopuszynski, Hongkun Wang, Maliha Zahid, G. Ian Gallicano

“…., hypertension, diabetes mellitus, coronary artery disease, etc.) lead to structural and functional changes in cardiomyocytes, resulting in HF. …”
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Network Meta-Analysis of Factors Influencing the Carbon Sink Capacity of Urban Park Green Spaces by Yutong JI, Tianyi LIN, Lian LIU, Xiong LI

“…While habitat composition and planting strategies offer substantial localized benefits, their variability necessitates tailored interventions informed by specific ecological and social contexts. …”
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Membrane Associated RNA‐Containing Vesicles Regulate Cortical Astrocytic Microdomain Calcium Transients in Awake Ischemic Stroke Mice by Zhongqiu Zhou, Ying Bai, Xiaochun Gu, Hui Ren, Wen Xi, Yu Wang, Liang Bian, Xue Liu, Ling Shen, Xianyuan Xiang, Wenhui Huang, Zhuojuan Luo, Bing Han, Honghong Yao

“…Abstract Astrocytic processes minutely regulate neuronal activity via tripartite synaptic structures. The precision‐tuning of the function of astrocytic processes is garnering increasing attention because of its significance in promoting brain repair following ischemic stroke. …”
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Diagnostic accuracy of apoptosis markers in non-alcoholic fatty liver disease in children by Yu. M. Stepanov, N. Yu. Zavhorodnia, O. Yu. Zavhorodnia, V. B. Yahmur, O. M. Tatarchuk, O. P. Petishko

“…Early diagnosis of rapidly progressive forms of NAFLD – non-alcoholic steatohepatitis (NASH) – is crucial, because therapeutic intervention in the early disease stages creates unique opportunities for the reversal of pathological changes and restoration of liver structure and function. …”
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The PRECISION study protocol: Can cervical stiffness in the second trimester predict preterm birth in high-risk singleton pregnancies? A feasibility, cohort study. by Elizabeth Medford, Steven Lane, Andrew Sharp, Angharad Care

“…Novel ways of assessing cervical structure and function may improve our ability to predict spontaneous PTB and refine preventative intervention. …”
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Protecting the Autonomy of Patients with Severe Mental Illness Through Psychiatric Advance Directive Peer-Facilitation by Nicholas Karasik

“…Guiding Distributive Justice: Capability Theory Capability theory is an account of justice opportunity that places a fundamental moral significance on individuals' ability to reach proper functioning and well-being.[52] Whether or not an individual can make use of a particular set of resources and convert them into a state of functioning depends on personal, sociopolitical, and environmental conditions ("conversion factors").[53] In this sense, liberty is not the absence of restraint from others or institutions but the freedom achieved through capability-enhancing relationships.[54] Within the context of bioethics, capability theory shifts focus toward creating circumstances by which individuals can direct their lives as they choose.[55] Acting in accordance with the principle of beneficence, peer-support specialists could enhance the capability of patients to be self-determined and autonomous, which would promote patient well-being and empowerment.[56] Those living with SMI, such as schizophrenia and bipolar disorder, are among the most disadvantaged in society, experiencing social and economic hardship related to their illness.[57] These individuals are often feared and rejected by others, which increases depression, lowers self-esteem, and engenders feelings of social isolation.[58] Compounding their challenges, especially for those facing structural inequalities, is insufficient access to appropriate mental health services supporting recovery.[59] Capability theory provides a sound justification for the resource distribution necessary to create and sustain a thriving network of peer-support specialists, to which those with SMI currently do not have access. …”
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De macrostructuur van het boek Samuël en de theologische implicaties daarvan by HJ Koorevaar

“… 1) There are two formal indications for structuring the Book of Samuel. a) The forms of government of the leading persons constitute the main structure. …”
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Neural correlates of device-based sleep characteristics in adolescents by Qing Ma, Barbara J. Sahakian, Bei Zhang, Zeyu Li, Jin-Tai Yu, Fei Li, Jianfeng Feng, Wei Cheng

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Differential effects of electroacupuncture and manual acupuncture on spontaneously hypertensive rats: insights from intestinal microbiota and metabolomics by Ji-Peng Liu, Long-Teng Tu, Ke-Zhen Yang, Yin-Yin Li, Yu Gong, Bing-Xuan Han, Chuan Liu, Tian-Qi Xia, Yu Liu, Xiao-Min Hao, Bing-Nan Yue, Jing Zhang, Bing-Hui Wang, Gui-Rong Luo, Qing-Guo Liu, Meng Xu

“…EA and MA influence the composition of intestinal microbiota in SHRs, aligning the microbial structure more closely with that of the WKY group. …”
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Non-suicidal self-injury in adolescence: a validation of the Chinese version of the Inventory of Statements About Self-Injury in student populations by Xinhe Tian, Xinhe Tian, Hebin Huang, Hebin Huang, Weicong Lu, Weicong Lu, Ruoxi Zhang, Ruoxi Zhang, Runhua Wang, Runhua Wang, Xiaoyue Li, Xiaoyue Li, Danping Li, Danping Li, Yanling Gao, Yanling Gao, Shiyun Wu, Shiyun Wu, Guiyun Xu, Guiyun Xu, Robin Shao, Robin Shao, Robin Shao, Kangguang Lin, Kangguang Lin, Kangguang Lin, Kangguang Lin

“…Moreover, the scores of the functions of the ISAS were correlated with depression (r=0.208, p<0.01), anxiety (r=0.223, p<0.01), suicidal ideation (r=0.322, p<0.01), and low self-control (r=-0.230, p<0.01).ConclusionThis study validates the Chinese ISAS as a reliable NSSI measure, identifies a two-factor structure, and aims to inform targeted interventions and future research on self-injury behaviors among Chinese adolescents.…”
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CD38‐NADase is a new major contributor to Duchenne muscular dystrophic phenotype by Antoine de Zélicourt, Abdallah Fayssoil, Mbarka Dakouane‐Giudicelli, Isley De Jesus, Ahmed Karoui, Faouzi Zarrouki, Florence Lefebvre, Arnaud Mansart, Jean‐Marie Launay, Jerome Piquereau, Mariana G Tarragó, Marcel Bonay, Anne Forand, Sophie Moog, France Piétri‐Rouxel, Elise Brisebard, Claudia C S Chini, Sonu Kashyap, Matthew J Fogarty, Gary C Sieck, Mathias Mericskay, Eduardo N Chini, Ana Maria Gomez, José‐Manuel Cancela, Sabine de la Porte

“…Here, we identified that deletion in mdx mice of CD38, a NAD+ glycohydrolase‐producing modulators of Ca2+ signaling, led to a fully restored heart function and structure, with skeletal muscle performance improvements, associated with a reduction in inflammation and senescence markers. …”
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Investigating the eye in Down syndrome as a window to Alzheimer’s disease: the REVEAL protocol – a clinical cross-sectional study by Henrik Zetterberg, Tunde Peto, Imre Lengyel, Kathryn Saunders, Sarah Atkinson, André Strydom, Julie-Anne Little, Elaine Murray, Jamie Mitchell, Aoife Mary Louise Hunter, Lajos Csincsik

“…The REVEAL study aims to examine changes in the structure and function of the eye in individuals with DS compared with those with mild cognitive impairment (MCI) and cognitively healthy control (HC) individuals. …”
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Dysbiosis of Gut Microbiota in Ankylosing Spondylitis Patients by Yang L, Wang K, Liu B, Chen T, Ma T, Cui Z, Zhang D, Zhang S, Liu X, Shen J, Lu H

“…Bioinformatic processing and statistical analysis were performed to assess the microbial community structure, diversity, and function.Results: The study revealed significant differences in gut microbiota composition between AS patients and healthy controls. …”
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A család ereje: A házasságban élés és a nagycsaládos lét kapcsolata a jóllét különböző mutatóival by Andrea FERENCZI, Zsuzsanna KÖVI, Veronika MÉSZÁROS

“…CONCLUSIONS – The findings highlight the complex interplay between gratitude and family as well as religious background. The protective function of dispositional gratitude may be especially relevant for the development of psychological prevention and intervention programmes, as it can contribute both to the enhancement of perceived social support and the maintenance of subjective well-being. …”
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