Effects of Shenyankang on expression of CTGF and FN in adriamycin-induced nephrosis rats by XIE Yi-feng, LI Yan-fang, ZHAO Xian-feng, LU Zhu-guang, JIANG Yao-ping

“…Results(1) Shenyankang intervention treatment could significantly reduce urinary protein level in nephrotic rats(P<0.05).(2) Shenyankang could significantly reduce serum creatinine, urea and uric acid levels(P<0.05).(3) Shenyankang could significantly improve the renal pathological structure of nephrotic rats, and inhibit the level of renal fibrosis(P<0.05);(4) Shenyankang could significantly reduce glomerular sclerosis index in rats with nephropathy(P<0.05);(5) Immunohistochemical results showed that Shenyankang could significantly inhibit the expression of CTGF and FN proteins in renal tissues of nephrotic rats(P<0.05).(6) The results of qPCR showed that Shenyankang could significantly inhibit the expression of CTGF and FN mRNA in renal tissues of nephrotic rats(P<0.05).(7) For nephrotic rats, the overall improvement level of Shenyankang was weaker than that of prednisone, but the therapeutic effect was still obvious. …”
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A staged approach to managing a combination of a terrible triad injury and an Essex–Lopresti fracture dislocation: an open forearm crush injury—a case report by Abdulla Abdelwahab, Ahmed Khairy Farahat Elsayed, Hamed Badawi

“…It results in damage to various structures, including bones, soft tissues, and neurovascular bundles, ultimately leading to functional impairment. …”
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Neuromodulation through brain stimulation-assisted cognitive training in patients with post-chemotherapy subjective cognitive impairment (Neuromod-PCSCI) after breast cancer: study... by Ulrike Grittner, Agnes Flöel, Sein Schmidt, Friederike Thams, Daria Antonenko, Eva-Lotta Brakemeier, Merle Rocke, Elena Knochenhauer, Anna Elisabeth Fromm, Nora Jansen, Samaneh Aziziaram, Antje Vogelgesang

“…A follow-up visit will be performed 1 month after intervention to assess possible long-term effects. In an exploratory approach, structural and functional MRI will be acquired before the intervention and at post-intervention to identify possible neural predictors for successful intervention.Ethics and dissemination Ethical approval was granted by the ethics committee of the University Medicine Greifswald (BB236/20). …”
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Ankle Sprains: Clinical Practice and Guideline-Based Treatment Strategies by Maciej Pachana, Piotr Kukuła, Maciej Ziomek, Marcin Piersiak, Hubert Sawczuk, Anna Tomasiewicz, Jan Zabierowski, Julia Marschollek

“…Timely and structured rehabilitation remains key to restoring ankle function. …”
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Forest Succession and Maternity Day Roost Selection by Myotis septentrionalis in a Mesophytic Hardwood Forest by Alexander Silvis, W. Mark Ford, Eric R. Britzke, Nathan R. Beane, Joshua B. Johnson

“…For northern bats, we suggest that day-roost selection is not a function of differences between individual tree species per se, but rather of forest successional patterns, stand and tree structure. …”
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Mechanistic Advances in Hypoglycemic Effects of Natural Polysaccharides: Multi-Target Regulation of Glycometabolism and Gut Microbiota Crosstalk by Liquan Zhou, Jiani Li, Chen Ding, Yimiao Zhou, Zuowei Xiao

“…Natural polysaccharides (NPs), as a class of bioactive macromolecules with multitarget synergistic regulatory potential, exhibit significant advantages in diabetes intervention. This review systematically summarizes the core hypoglycemic mechanisms of NPs, covering structure–activity relationships, integration of the gut microbiota–metabolism–immunity axis, and regulation of key signaling pathways. …”
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# Language processing characteristics in normal pressure hydrocephalus: insights from eye-tracking analysis of incorrect responses by Ji-Yeong Kim, Jiho Lee, Nayeon Kim, Ki-Su Park, Janghyeok Yoon, Kyunghun Kang, Ji-Wan Ha

“…This enlargement compresses several brain structures, impairing functions such as visual perception, semantic memory processing, and phonological encoding contributing to language processing difficulties. …”
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The death education needs of patients with advanced cancer: a qualitative research by Shenghuan Yang, Chao Yan, Jing Li, Yinglu Feng, Huizini Hu, Yonghong Li

“…It’s essential to comprehensively assess the current state and needs of patients, engaging in ongoing interventions tailored to individual patient circumstances. …”
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Innovative gene delivery systems for retinal disease therapy by Hongguang Wu, Ling Dong, Shibo Jin, Yongwang Zhao, Lili Zhu

“…The human retina, a complex and highly specialized structure, includes multiple cell types that work synergistically to generate and transmit visual signals. …”
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Neurophysiological Effects of Virtual Reality Multitask Training in Cardiac Surgery Patients: A Study with Standardized Low-Resolution Electromagnetic Tomography (sLORETA) by Irina Tarasova, Olga Trubnikova, Darya Kupriyanova, Irina Kukhareva, Anastasia Sosnina

“…The use of a multitask approach that combines motor component with various cognitive tasks in a virtual environment can optimize cognitive and physical functions and improve the quality of life of cardiac surgery patients. …”
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Unlocking health insights: exploring intention to adopt district health information systems in Bahir Dar City, northwest Ethiopia by Habtamu Alganeh Guadie, Amarech Kindie, Hunegnaw Almaw Derseh, Desta Debalkie Atnafu

“…Therefore, it is imperative to implement targeted interventions before system rollout, including practice-based training, fostering positive attitudes, and enhancing knowledge of the system's usability and functionality to improve the adoption of the district health information system.…”
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Complex associations between anxiety, depression, and resilience in a college student sample: a network analysis by Hui Wang, Min Wang, Xiuchao Wang, Tingwei Feng, Xufeng Liu, Wei Xiao

“…Prioritizing these two symptoms in future research could yield greater intervention benefits.…”
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A way of relating to life; myself and others - a thematic analysis of patients’ experience of having an eating disorder by Malin Bäck, Sanna Aila Gustafsson, Karin Jacobson, Theresia Ljung, Rolf Holmqvist, Gerhard Andersson

“…Abstract Background Eating disorders are psychiatric conditions that extend beyond concerns with weight, body and shape, encompassing complex issues related to self-esteem, emotion regulation and interpersonal functioning. Moreover, co-occurring depression, often undiagnosed, is a common complicating factor. …”
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A comparative assessment of WASH adherence among public and private school students in a rural district in Nigeria by Ayoola O. Bosede, Rejoice C. Enwenonu, Justina U. Udensi, Onyenonachi C. Ihejirika, Kolawole C. Akindulureni, Onyima C. Emenonu, Thelma C. Mezieobi

“…Methods A descriptive cross-sectional study design was employed, and data were collected using a structured questionnaire and an observational checklist. …”
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Contextualizing post day-one childhood immunization in-take drop-off rate in Nigeria: An assessment of working mothers in Ibadan [version 2; peer review: 1 approved, 3 approved wit... by Olugbenga S. Falase, Folakemi A. Amodu, Olukemi K. Amodu, Taiwo H. Olajide, Mofeyisara O. Omobowale

“…Achieving this understanding could involve translating vaccine names and functions into indigenous terms, enhancing clarity and comprehension. …”
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An approach to reconstructing a segmental defect of the mandible involving the condyle secondary to nodular fasciitis in a pediatric patient: a case report by Nitin Bhola, Shreya Pawar

“…Prompt recognition and surgical intervention can lead to favorable results, restoring both function and esthetics for patients affected by this benign yet challenging condition.…”
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The ileocecal valve in transabdominal ultrasound Part 1: Sonographic anatomy and technique by Smereczyński Andrzej, Kołaczyk Katarzyna, Goncerz Grzegorz

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Therapeutic management for patients with trunk and extremities integumentary tissues defects of traumatic genesis by O. V. Ponomarenko

“…Objective: To improve the results of treating patients with wounds, functional and aesthetic defects of mechanical origin by developing a comprehensive program of surgery to restore the form and function of trunk and limbs. …”
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A rare case of adult ovarian inguinal hernia with an associated pelvic ectopic kidney by Komal Mishra, Pratapsingh Parihar, Rakshanda Agrawal

“…Accurate diagnosis relies heavily on imaging modalities, which guide the surgical approach and help rule out complications like torsion. Early surgical intervention is imperative to prevent potential morbidity and preserve ovarian function. …”
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Receipt of Recovery-Oriented Care Practices During Hospitalization for Sepsis by Megan A. Watson, MD, MPH, Clare Anderson, MD, Kevin J. Karlic, MD, Cainnear K. Hogan, MSW, Sarah Seelye, PhD, Stephanie P. Taylor, MD, MS, Hallie C. Prescott, MD, MSc

“…Three-hundred sixty-five sepsis hospitalizations met study inclusion criteria. Using structured chart review, we determined receipt of the following recovery-based care practices during hospitalization: medication optimization, functional status evaluation at discharge, sepsis education, and scheduled follow-up within 2 weeks. …”
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