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1581
Characterization of Salmonella adaptation in response to phage treatment in broiler chickens
Published 2025-08-01“…Therefore, bacterial resistance what is often view as a limitation of phage therapy may be leveraged as a functional advantage in phage cocktail design.…”
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1582
Intensive and standard group-based treatment for persons with social communication difficulties after an acquired brain injury: study protocol for a randomised controlled trial
Published 2019-09-01“…Introduction Social communication difficulties (SCDs) occur frequently after an acquired brain injury (ABI) and have disabling consequences, but effective interventions are scant. Group Interactive Structured Treatment (GIST) is a holistic group treatment targeting SCD that has received empirical support.Objective To determine the efficacy of two GIST protocols, standard GIST and a newly developed intensive GIST, comparing standard GIST results to a wait-list control group (WL), as well as to intensive GIST received by participants following WL. …”
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1583
Protein Lactylation: A new jewel in the crown
Published 2025-06-01“…Lactylation is a newly identified post-translational modification that has emerged as a crucial epigenetic regulator, significantly influencing cellular functions and disease processes. Lactylation involves the addition of lactate, a glycolysis byproduct, to lysine residues in proteins, particularly histones. …”
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1584
Targeting the glymphatic system to promote α-synuclein clearance: a novel therapeutic strategy for Parkinson’s disease
Published 2026-01-01“…The review begins with an overview of the glymphatic system and details its anatomical structure and physiological functions that facilitate cerebrospinal fluid circulation and waste clearance. …”
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1585
Navigating pressure and connection: goal orientation, coach-athlete relationships, and burnout among Chinese collegiate athletes—a mixed-methods study
Published 2025-07-01“…This suggests that effective interventions should target both individual (e.g., promoting task orientation) and relational factors (e.g., enhancing CAR closeness and complementarity).…”
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1586
UPLC-Q-TOF-MS-based unbiased serum metabolomics investigation of cholangiocarcinoma
Published 2025-04-01“…These findings could contribute to the development of diagnostic strategies and therapeutic interventions for CCA.…”
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1587
Experiences of healthcare interactions before and after suicidal behaviour among older adults attending geropsychiatric services: an interpretative phenomenological analysis
Published 2025-05-01“…Objectives Physical illness and functional disability are common in older adult populations and strongly linked to suicidal behaviour. …”
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1588
Qualitative study exploring the key determinants of information gathering to inform the management of over-the-counter (OTC) consultations in community pharmacies
Published 2019-08-01“…This study highlights the importance of tailoring interventions to reflect different roles, functions and responsibilities of community pharmacy personnel.…”
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1589
From Hope to Heartache: A Case Report of Treatment Failure and its Impact on a 1-year-old with Bilateral Radial Aplasia in a Resource-Limited Setting
Published 2025-04-01“…In addition, it aims to stimulate the interest of the global orthopedics community to develop interventions or modify current treatment options that can be successfully implemented in low-resource settings to improve outcomes, especially the functionality of the limbs. …”
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1590
Dimethyl α-ketoglutarate ameliorates cisplatin-induced acute kidney injury by modulating mitophagy through the PINK1/Parkin pathway
Published 2025-08-01“…The levels of intracellular reactive oxygen species (ROS) and mitochondrial membrane potential (MMP) were assessed using optical microscopy. Renal function was evaluated using absorbance spectroscopy. …”
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1591
Molecular architectures of glycosylated dendronized bottle brushes in action: Biocompatibility and anti-amyloidogenic activity of pseudo-glycodendrimers
Published 2025-06-01“…Importantly, it is demonstrated that PGDs can be multi-functionalized by various sugar molecules, dyes, and/or peptides in a final one-pot approach. …”
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1592
Lactiplantibacillus plantarum FRT4 protects against fatty liver hemorrhage syndrome: regulating gut microbiota and FoxO/TLR-4/NF-κB signaling pathway in laying hens
Published 2025-03-01“…Lp. plantarum FRT4 improved the structure and metabolic functions of gut microbiota, and regulated the relative abundances of dominant phyla (Bacteroidetes, Firmicute, and Proteobacteria) and genera (Prevotella and Alistipes). …”
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1593
Brain Connectivity Yields Insights into the Pathogenesis of Epilepsy and Subtypes: Evidence from Mendelian Randomization Analysis
Published 2025-01-01“…This insight could yield crucial intervention strategies to different subtypes of epilepsy at the level of brain structure and functional networks.…”
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1594
Development and psychometric evaluation of the 12-item Polish version of the Pain Vigilance and Awareness Questionnaire
Published 2025-07-01“…Study 2 involved 148 hospital-recruited chronic pain patients who completed the adapted scale and measures of pain intensity and functional limitations. None of the previously proposed models describing the factor structure of the PVAQ scale adequately fit the data. …”
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1595
A comprehensive review of rehabilitation approaches for traumatic brain injury: efficacy and outcomes
Published 2025-06-01“…Patient-centered care is emphasized as a core element—rehabilitation plans are tailored to each individual’s cognitive profile, functional needs, and life goals. Studies show this approach leads to better outcomes in executive functioning, emotional wellbeing, and community reintegration. …”
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1596
Pollen–Food Allergy Syndrome: Allergens, Clinical Insights, Diagnostic and Therapeutic Challenges
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1597
Narrative production abilities of children with autism
Published 2025-06-01“…Macrostructure analysis examined the organization and structure of the narratives while microstructure analysis focused on linguistic elements such as syntax and word use. …”
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1598
Diagnosis and Management of Giant Hepatic Hemangioma: The Usefulness of Contrast-Enhanced Ultrasonography
Published 2013-01-01“…The major advantage is the real-time observation of the vascular structure and function of the Kupffer cells. By this procedure, we can carefully follow the tumor growth or character change in a hemangioma and decide the timing of therapeutic intervention, since abdominal pain, abdominal mass, consumptive coagulopathy, and hemangioma growth are the signs for the therapeutic intervention. …”
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1599
The Long-Term Effects of Alcohol on the Central Nervous System: Mechanisms, Cognitive Decline, and Associated Disorders
Published 2025-04-01“…These effects are mediated by mechanisms such as oxidative stress, neuroinflammation, and disruptions in neurotransmission. Structural changes, including gray matter loss and hippocampal atrophy, underlie functional deficits such as memory impairment, cognitive decline, and emotional dysregulation. …”
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1600
Successful surgical management of cervical tuberculous spondylitis with tetraparesis in a 17-year-old patient: A case report
Published 2025-02-01“…Post-operatively, he received anti-tuberculosis drug regimen for 12 months and followed a structured rehabilitation program. The patient's motor function improved from 2/5 to 5/5, with full recovery within 12 months post-operatively. …”
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