Determinants of child physical health development in Bangladesh: a study of key socioeconomic and cultural influences by Riyadh Hossain, Mohammad Omar Faruk, Najma Begum

“…Abstract Physical health is the overall well-being of the body, ensuring the proper functioning of organs, muscles, and systems. It includes fitness, nutrition, disease prevention, and healthy lifestyle choices. …”
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Investigating the regulation of the miR-199a-3p/TGF-β/Smad signaling pathway by BSHXF drug-containing serum combined with ADSCs for delaying intervertebral disc degeneration by Enxu Liu, Enxu Liu, Yu Sun, Yu Sun, Lei Yang, Lei Yang, Haobo Jiang, Haobo Jiang, Fei Sun, Long Chen, Jiahao Duan, Jiahao Duan, Shaofeng Yang, Shaofeng Yang

“…BSHXF restored TGF-β/Smad pathway activity by downregulating miR-199a-3p expression, thereby improving disc structure and function. This integrated approach offers a novel multi-target intervention strategy for IDD, demonstrating significant therapeutic potential.…”
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CLINICAL AND EXPERIMENTAL ARGUMENTATION OF MODIFIED METHOD FOR PERI-IMPLANT BONE REDUCTION EVALUATION DURING VARIOUS SCHEMES OF PROSTHETIC REHABILITATION by A.T. Kenyuk

“…The obtained data allow to individualize the approach of assessing the quality of complex iatrogenic interventions conducted with the ability to analyze the impact of various factors on peri-implant bone changes, including the adequacy of choosing specific schemes of prosthetic rehabilitation of dental patients supported by implants structures. …”
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A Review of Multidisciplinary Evidence on the Role of Urban Green Space in Improving the Sleep Quality of the Elderly by Ning KANG, Han XIE, Tao JIANG

“…Consequently, prioritizing the advancement of their planning, design, and functional optimization is imperative. Finally, rigorous evaluation of the effectiveness of sleep quality improvement interventions is essential. …”
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Spatiotemporal characterization of the dynamic changes in the intestinal microbiota of Taihe Silky Fowl by Wentao Li, Haoneng Guo, Youping Wu, Yizhen Wang, Zeqing Lu

“…Conclusions In conclusion, the diversity, structure, composition, community relationships and functions of the intestinal microbiota in Taihe Silky Fowl dynamically changed with age in different intestinal regions.…”
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Characterising the gut microbiome in veterans with Gulf War Illness: a protocol for a longitudinal, prospective cohort study by Kelsey Baubie, Catherine Shaughnessy, Nasia Safdar, Julie A Keating, Ashley E Kates, Nathan Putman-Buehler, Lauren Watson, Nadia Dominguez, Kal Watson, Dane B Cook, David Rabago, Garret Suen, Ronald Gangnon

“…In this longitudinal cohort study, we are comparing the diversity (structure) and the metagenomes (function) of the gut microbiome between Gulf War Veterans with and without GWI. …”
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Metformin carbon dots enhance neurogenesis and neuroprotection in Alzheimer's disease: A potential nanomedicine approach by Jing Zhang, Xuehan Yang, Sushan Wang, Jianhua Dong, Meishuang Zhang, Ming Zhang, Li Chen

“…We also examined neuronal structure by assessing Map2/NF-H/PSD95/SYN expression in the hippocampus, finding that CMCDs robustly strengthened neuronal structure. …”
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Features and Outcomes of Penetrating Keratoplasty in Combined Opto-reconstructive Surgery for Combat Eye Injury and its Complication by A. N. Kulikov, S. V. Churashov, E. V. Danilenko, P. S. Voronkov, E. S. Golovneva

“…Patients underwent examination to reveal and localize damaged intraocular structures and intraocular foreign bodies (IOFB), determine the prognosis of visual functions, as well as impression cytology. …”
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“Locality – Adaptation” Research of Hydropower Resettlement Communities in the Jinsha River Basin: A Case Study of Ludila Hydropower Station by Fang WANG, Zhuoqi LI, Haoyi XU, Jiaqi YAN

“…At the settlement scale, the Mask Region-based Convolutional Neural Network (Mask R-CNN) deep learning model is utilized to identify architectural spatial features, categorizing three typical building types: traditional pitched-roof buildings, uniformly planned flat-roof buildings, and color steel plate-modified structures. Through multi-source data fusion (including remote sensing, demographic statistics, and compensation records) and field investigations, the research quantitatively analyzes the “locality – adaptation” reconstruction process of resettlement communities across the three spatial dimensions of living, production, and cultural spaces.Results1) Land cover evolution: Water storage of hydropower station inundates 37.12 km2 of land (including 21.61 km² of high-quality cultivated land), resulting in a loss of 43.68% of settlement production space. 2) Adjustment of architectural space: 65.8% of dwellings in the original villages are traditional timber-earth buildings with a tile roof, which adapt to the climate environment of concentrated rainfall and sufficient sunshine in the Jinsha River Basin. 48.7% of the resettlement sites adopt unified flat roof planning, and 51.3% realize functional optimization through self-construction or renovation, with the average renovation area reaching 230.9 m2. 3) Transformation of livelihood system: The annual compensation mechanism only restores 15.79% of the cultivated land allocation before resettlement, and the proportion of compensation income drops from 82.71% in the initial stage of relocation to 33.15% after long-term resettlement, driving the adjustment of crop structure to high value-added cash crops. 4) Cultural space reconstruction: In the context of the disappearance of traditional water transport functions, the three cultural relics reconstructed in different places show a symbolic turn. …”
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Unraveling the frequency of intestinal constipation in woman with urinary incontinence: a descriptive observational study by Bruna Isadora Thomé, Karoleen Oswald Scharan, Gisela Maria Assis, Auristela Duarte de Lima Moser

“…Conclusion: The high frequency of functional constipation in women with urinary incontinence highlights a significant impact on quality of life and underscores the importance of integrated, conservative therapeutic strategies, including early lifestyle interventions such as regular physical activity, to prevent worsening of both conditions. …”
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Biofilm formation by the host microbiota: a protective shield against immunity and its implication in cancer by Elena Montanari, Giancarla Bernardo, Valentino Le Noci, Martina Anselmi, Serenella M. Pupa, Elda Tagliabue, Michele Sommariva, Lucia Sfondrini

“…These microbial inhabitants often exhibit biofilm-like structures, which may protect them from host immune responses and therapeutic interventions. …”
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Evaluating the Impact of Near-Natural Restoration Strategies on the Ecological Restoration of Landslide-Affected Areas Across Different Time Periods by Sibo Chen, Jinguo Hua, Wanting Liu, Siyu Yang, Wenli Ji

“…Near-natural restoration drives system recovery through the “selection of native species via competition and activation of microbial functional groups”. The 6–11-year period post-landslide is a critical window for structural optimization, and we recommend phased dynamic regulation to balance biodiversity and ecological functions.…”
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Regulation of EMT-MET and chemoresistance by the Lc3Cer-synthase B3GNT5 by Laura E. Clark, Katherine Hylton Rorie, Amanda J. G. Dickinson, Santiago Lima

“…Abstract Background Glycosphingolipids (GSL) are essential components of the plasma membrane where they are known to play key structural and functional roles and are known to influence molecular processes involved in cancer malignancy, including multi-drug chemoresistance, the epithelial to mesenchymal transition (EMT), and the activation or receptor tyrosine kinases (RTK). …”
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Exploring the Gut Microbiota–Retina Axis: Implications for Health and Disease by Nicola Schiavone, Giulia Isoldi, Sara Calcagno, Elisabetta Rovida, Emiliano Antiga, Carolina Vieira De Almeida, Matteo Lulli

“…The gut microbiota represents a rich and adaptive microbial network inhabiting the gastrointestinal tract, performing key functions in nutrient processing, immune response modulation, intestinal wall protection, and microbial defense. …”
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Therapist experiences with implementation of blended (iCBT and face-to-face) treatment of alcohol use disorder (Blend-A): mixed methods study by Kristine Tarp, Kristine Tarp, Kristine Tarp, Regina Christiansen, Regina Christiansen, Randi Bilberg, Caroline Dalsgaard, Caroline Dalsgaard, Simone Borkner, Simone Borkner, Marie Folker, Anette S. Nielsen, Anette S. Nielsen, Anette S. Nielsen

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Cohort protocol: risk assessment of maternal inflammation and early brain development in infants and young children based on multi-source data modeling by Xianghui Huang, Xianghui Huang, Cuimin Su, Ying Lin, Ying Lin, Tianyi Zhou, Ruming Ye, Ruming Ye, Dan Li, Dan Li, Miaoshuang Liu, Guanhong Wu, Wanting Li, Namei Xie, Xiaofang Deng, Nanxi Zhu, Shaohong Lin, Qin Li, Kai Yan, Deyi Zhuang, Deyi Zhuang

“…Children's cognitive, emotional, and linguistic development was evaluated, and blood samples were obtained for whole-exome sequencing and exposure-related biomarker analysis.ConclusionIn this study, we used deep learning artificial intelligence to construct an early risk assessment model for infant brain development based on the developmental trajectory and developmental results of early brain structure, function, and connections under the complex interaction of “gene-image-environment-behavior” multi-factors, which can improve the early identification and precise intervention of problems in this period, and improve infants cognitive learning and work performance in childhood, adolescence and even adulthood.Clinical trial registrationhttps://www.clinicaltrials.gov/; identifier [NCT05040542].…”
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Biological effect of acupuncture on peripheral facial paralysis by Wenwen Duan, Dan Chen, Zubo Huang, Yue Zeng, Shanshan Liu, Chao Wang, Hao Zhou

“…This article will sort out and summarize the existing research mechanisms from the following aspects: inflammatory response, immune regulation, neurotransmitters, immune response, facial microcirculation, oxidative stress, changes in nerve structure and function, specificity of acupoints, acupuncture intervention time, and other potential mechanisms aiming to provide a scientific foundation for the role of acupuncture in the treatment of peripheral facial paralysis. …”
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Waterside Mansion of Esma Sultan within the Scope of Contemporary Restoration Work by Fatma Sedes, Ezgi Yilmaz, Serhat Arman Çikrikçi

“…It is necessary to determine the necessary elements for the restoration processes of historical buildings, the criteria and decisions of intervention, and the characteristics of the structure before the intervention. …”
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Predictors of Cognitive Defects and Its Prevention Capabilities in Premature Infants by Irina A. Belyaeva, Alexander A. Baranov, Leyla S. Namazova-Baranova, Kamilla E. Efendieva, Polina S. Arimova, Alexey I. Molodchenkov, Elena P. Bombardirova, Georgiy A. Karkashadze, Tatiana V. Turti, Elena A. Vishnyova

“…The data of longitudinal researches of the premature infants’ development until reaching their adulthood is presented. The structure of cognitive defects in this population is studied. …”
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Social innovations and drivers in flood early warning systems: A community‐based transboundary perspective from Elegu flood plain in Northern Uganda by Vincent Canwat

“…However, a global picture of how they function on the ground, especially in developing countries, is lacking. …”
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