A Comprehensive Resiliency Framework: Theoretical Model, Treatment, and Evaluation by Elyse R Park PhD, Christina M Luberto PhD, Emma Chad-Friedman, Lara Traeger, Daniel L Hall PhD, Giselle K Perez PhD, Brett Goshe PhD, Ana-Maria Vranceanu PhD, Margaret Baim MS, ANP-BC, John W Denninger MD, PhD, Gregory Fricchione MD, Herbert Benson MD, Suzanne C Lechner PhD

“…Background There is heterogeneity in conceptualizations of resiliency, and there is, to date, no established theoretically driven resiliency assessment measure that aligns with a targeted resiliency intervention. We operationalize resiliency as one’s ability to maintain adaptive functioning in response to the ongoing, chronic stress of daily living, and we use a novel resiliency measure that assesses the target components of an evidence based resiliency intervention. …”
Get full text

Mapping teacher wellbeing in Slovakia: insights into resilience, relationships, and support needs by Lenka Janik Blaskova, Lenka Janik Blaskova, Liz Winter

“…Rather than collapsing wellbeing into a single metric, we apply a simple theoretical model that distinguishes self-perceived competence and affect, providing a more comprehensive representation of teacher wellbeing.ResultsOur findings reveal distinct patterns based on gender and years of service in how teachers experience hedonic wellbeing (happiness and satisfaction) and eudaimonic wellbeing (optimal functioning and meaningfulness). Relationships—both within and beyond the profession—emerge as critical determinants of wellbeing, surpassing formal support structures in importance.DiscussionThese results inform recommendations for professional development initiatives grounded in a national perspective, with the potential to enhance teacher support networks and address systemic gaps. …”
Get full text

Filamentation of hCTPS1 with CTP by Chen-Jun Guo, Xiaojie Bao, Ji-Long Liu

“…Our findings not only elucidate a novel regulatory mechanism of hCTPS1 activity but also deepen the understanding of how metabolic enzymes utilize filamentation as a conserved strategy for functional regulation. This study opens new avenues for targeting hCTPS1 in therapeutic interventions.…”
Get full text

Prediction of Expected Fouling Time During Transmembrane Transition in Reverse Osmosis Systems by Jozsef Lakner, Gabor Lakner

“…However, due to the porous structure of membranes, they are prone to fouling, which reduces their efficiency and can eventually render the membranes incapable of functioning. …”
Get full text

Improving reading competence in aphasia with combined aerobic exercise and phono-motor treatment: Protocol for a randomized controlled trial. by Olga Boukrina, Elizabeth B Madden, Brian M Sandroff, Xiangqin Cui, Abubakar Yamin, Yekyung Kong, William W Graves

“…Additionally, it investigates the immediate and sustained impacts of the intervention on CBF, functional connectivity, and task-evoked brain activity. …”
Get full text

Genetic and Molecular Characterization of Atopic Eczema: A Comprehensive Bioinformatics Analysis of Gene Interactions and Pathways by Basannagari Sreenivasa Sindhu, Usha S Adiga, Kukkapalli Prathap Kumar, Nagishetty Sindhuja, Eddula Venkata Ravikanth, Karanam Harikumar Sneha

“…Comprehensive gene enrichment analyses were conducted using databases for Gene Ontology biological processes, cellular components, and molecular functions. In addition, pathway mapping was performed using WikiPathways to delineate critical signaling interactions. …”
Get full text

Health Status After Total Hip Arthroplasty: A Literature Review by Mădălin Bulzan, Florica Voiță-Mekeres, Simona Cavalu, Gheorghe Szilagyi, Gabriel Mihai Mekeres, Lavinia Davidescu, Călin Tudor Hozan

“…The early implementation of tailored, multidisciplinary perioperative pathways—including structured rehabilitation programs, routine psychological screening and intervention, nutritional counseling for weight management, and active family involvement—may optimize functional recovery, reduce complications, and maximize long-term QoL in patients undergoing THA. …”
Get full text

Inhibition of 5-hydroxyindoleacetic acid to reduce neutrophil extracellular trap production improves lung condition in chronic obstructive pulmonary disease mice by Qiang Zeng, Lei Xue, Wu Li, Cheng Liang, Weijia Zhou, Wei Xiong, Xiaotian Dai

“…The metabolism of serotonin to 5-hydroxyindoleacetic acid (5-HIAA) in platelets may be the key to this difference.Objective The study aimed to determine whether 5-HIAA can influence NET production and thus play a role in COPD.Methods After a 4-hour co-incubation with lipopolysaccharide (LPS) and 5-HIAA, NET and ROS levels in the culture medium were measured by ELISA, and NET production with aryl hydrocarbon receptor (AHR) expression in adherent cells were analyzed by immunofluorescence.A COPD model was established in C57BL/6 mice through smoke exposure combined with LPS tracheal administration, followed by selegiline or 5-HIAA treatment. Post-intervention, lung function tests and sample collection were performed. …”
Get full text

Ahmed drainage valve surgery in the various forms of glaucoma in children by T. N. Iureva, O. I. Mikova, N. V. Volkova, I. V. Pomkina

“…In one case, the epithelial ingrowth with occlusion of the capillary was observed in the course of the wound channel, it required the implantation of a second drainage in free quadrant of the eyeball. Reduced visual function after surgery was observed in only one patient as a result of hemorrhagic choroidal detachment, the cause of it can bea post-operative hypotension and absence of forming structures on the background of aphakia and avitria.Conclusion. …”
Get full text

Ovarian Torsion: Presentation and Management in a Pediatric Patient by Katie P. Nguyen, William L. Valentino, Duy Bui, Honey Milestone

“…Appropriate diagnosis and timely surgical gynecological intervention allowed this pediatric patient to salvage and preserve ovarian function.…”
Get full text

A Perspective on Electrical Stimulation and Sympathetic Regeneration in Peripheral Nerve Injuries by Tina Tian, Amy M. Moore, Paul A. Ghareeb, Nicholas M. Boulis, Patricia J. Ward

“…The current standard of care relies on the slow and inefficient process of nerve regeneration after surgical intervention. Electrical stimulation (ES) has been shown to both experimentally and clinically result in improved regeneration and functional recovery after PNI for motor and sensory neurons; however, its effects on sympathetic regeneration have never been studied. …”
Get full text

Modeling Intra-Organization Fragmentation and Integration to Enhance Performance in Industrialized Timber Construction by Harrison Mesa, Macarena Ramírez, Pablo Guindos, Manuel Carpio

“…The VDT’s baseline results reveal significant rework from inadequate early integration among specialties and functional departments, increasing the project schedule. …”
Get full text

Measuring health-related quality of life: a qualitative study of mental health patients’ experiences of impacts of mental health issues by Yeujin Ki, Andrew Athan Mcaleavey, Janne-Merete Torset Øien, Tron Anders Moger, Christian Moltu

“…Additionally, the impact of unpredictability on daily functioning and the role of sleep difficulties should be incorporated. …”
Get full text

Biomimetic Proteoglycans for Intervertebral Disc (IVD) Regeneration by Neha Chopra, James Melrose, Zi Gu, Ashish D. Diwan

“…A major impediment to the development of any prospective cell-driven recovery of functional properties in degenerate IVDs is the diminishing IVD cell numbers and viability with ageing which cannot sustain such a recovery process. …”
Get full text

Nutrition and Exercise in Critical Illness Trial (NEXIS Trial): a protocol of a multicentred, randomised controlled trial of combined cycle ergometry and amino acid supplementation... by Daren K Heyland, Andrew Day, G John Clarke, Catherine (Terri) Hough, D Clark Files, Marina Mourtzakis, Nicolaas Deutz, Dale M Needham, Renee Stapleton

“…We hypothesise that this novel combined intervention will (1) improve physical functioning at hospital discharge; (2) reduce muscle wasting with improved amino acid metabolism and protein synthesis in-hospital and (3) improve patient-reported outcomes and healthcare resource utilisation at 6 months after enrolment. …”
Get full text

AI-driven preclinical disease risk assessment using imaging in UK biobank by Dmitrii Seletkov, Sophie Starck, Tamara T. Mueller, Yundi Zhang, Lisa Steinhelfer, Daniel Rueckert, Rickmer Braren

“…Abstract Identifying disease risk and detecting disease before clinical symptoms appear are essential for early intervention and improving patient outcomes. In this context, the integration of medical imaging in a clinical workflow offers a unique advantage by capturing detailed structural and functional information. …”
Get full text

Research progress on the mechanism of succinylation in tumorigenesis and development by Su Xiayi, Bai Jie, Zhang Baihong, Liu Yong

“…Succinylation is a post-translational modification process that plays a crucial role in regulating protein structure and function and is implicated in the pathogenesis of various diseases. …”
Get full text

Regulatory culture and architectural project by Mario Losasso

“…One notable aspect is the adoption of the regulating principle of ‘do no significant harm’ (DNHS), along with the choice to link together the numerous intervention proposals aimed at implementing structural and lasting changes in the built environment, both in terms of implementation and methodology. …”
Get full text

Relationship Between Cognitive Impairment and Quality of Life in Systemic Lupus Erythematosus: A Multimodal Neuroimaging Perspective by Liu Q, Liu M, Zou Q

“…Multimodal MRI techniques offer valuable insights into structural, functional, and metabolic abnormalities across both localized brain regions and global neural networks, facilitating comprehensive assessment of SLE-related cognitive dysfunction. …”
Get full text

Ossified Cephalohaematoma: An Unusual Case of Calvarial Mass in Infancy by Hamsavahini Mohan, Allen David Solomon, Nandini Vasudevan, Priya Jose

“…Despite the condition’s tendency to resolve spontaneously, surgical excision was required, leading to the successful correction of the skull deformity with no recurrence. Early intervention ensured favourable cosmetic and functional outcomes. …”
Get full text