The gene regulatory mechanisms shaping the heterogeneity of venom production in the Cape coral snake by Pedro G. Nachtigall, Brett R. Hamilton, Taline D. Kazandjian, Paolo Stincone, Daniel Petras, Nicholas R. Casewell, Eivind A. B. Undheim

Get full text

Effects of high intensity training and high volume training on endothelial microparticles and angiogenic growth factors. by Patrick Wahl, Felix Jansen, Silvia Achtzehn, Theresa Schmitz, Wilhelm Bloch, Joachim Mester, Nikos Werner

“…For all these measurements venous blood samples were taken pre, 0', 30', 60' and 180' after each intervention. Furthermore, in vitro experiments were performed to explore the effect of collected sera on target endothelial functions and MP uptake capacities.…”
Get full text

Therapeutic potential of Medical Nutrition Therapy (MNT) in Non-Alcoholic Fatty Liver Disease (NAFLD) by Abdul-Malik Bawah, Kasim Abdulai, Priscilla Cecilia Akpene Amenya

“…Regression analysis with interaction terms assessed the impact of educational level and occupational type on MNT outcomes. Results: The MNT intervention group showed significant improvements in liver function tests (ALT and AST decreased by 25 % on average, p < 0.01) and metabolic markers (BMI reduced by 3 %, p < 0.01). …”
Get full text

Spatial Complex Morphological Evolution and Influencing Factors for Mountain and Seaside Resort Tourism Destinations by Huiqiang Ma, Jianchao Xi, Qing Wang, Jiale Liu, Zhigang Gong

“…The study contributes to complex morphological evolution from the perspectives of external structure expansion and internal function reconstruction, revealing the spatial characteristics and explaining the influencing factors. …”
Get full text

A Systems Approach to Monitoring Antimicrobial Consumption and Use in Uganda by Miss Vivian Twemanye, Ms Harriet Akello, Mr Moses Mukiibi, Mr Richard Walwema, Dr Jonathan Mayito, Dr Morries Seru

“…Methods: Uganda's approach recognizes that AMUC is influenced by healthcare delivery, governance structures, financing mechanisms, workforce capacity, and information systems. …”
Get full text

Eccentric strengthening vs. conventional therapy in sub-acute stroke survivors: a randomized controlled trial by Kalthoum Belghith, Kalthoum Belghith, Mustapha Zidi, Lhéo Vincent, Lhéo Vincent, Jean-Michel Fedele, Rayan Bou-Serhal, Wael Maktouf

“…Assessments will be conducted at baseline, and after ET intervention, encompassing clinical, biomechanical, and functional evaluations. …”
Get full text

Immunohistochemical and Ultrastructural Study of the Degenerative Processes of the Hip Joint Capsule and Acetabular Labrum by Riana Maria Huzum, Bogdan Huzum, Marius Valeriu Hînganu, Ludmila Lozneanu, Fabian Cezar Lupu, Delia Hînganu

Get full text

Hip Microinstability Associated with Subclinical Femoroacetabular Impingement in a Ballet Dancer: A Case Report by Sergey A. Gerasimov, Ekaterina A. Morozova

“…In the present case, arthroscopic correction of structural damages made it possible to achieve excellent functional results through the planning and performance of surgical intervention taking into account the concept of microinstability.…”
Get full text

中學生成長型思維與學習投入之關係： 以後設認知與羞愧感為中介變項 A Study on the Impact of Growth Mindset on Learning Engagement Among Junior and Senior High School Students: Exploring the Mediating Roles of Metac... by 王佳琪 Chia-Chi Wang, 孫國瑋 Guo-Wei Sun

“…本研究探討中學生成長型思維與學習投入的關係，並檢驗後設認知與羞愧感的中介效果，以1,167位國、高中生為研究對象，完成「思維量表」、「後設認知量表」、「羞愧感量表」與「學習投入量表」等研究工具的填答，採結構方程模式（Structural Equation Modeling, SEM）進行分析。研究結果顯示，一、學生的成長型思維能正向預測後設認知、後設認知能直接正向預測學習投入、成長型思維會間接正向預測學生的學習投入；二、學生的成長型思維能直接負向預測羞愧感、羞愧感會直接負向預測學生的學習投入；三、學生的後設認知與羞愧感，在成長型思維與學習投入間具有中介效果。…”
Get full text

'Special k' and a loss of cell-to-cell adhesion in proximal tubule-derived epithelial cells: modulation of the adherens junction complex by ketamine. by Claire E Hills, Tianrong Jin, Eleftherios Siamantouras, Issac K-K Liu, Kieran P Jefferson, Paul E Squires

“…To date however, we know nothing of a role for Ketamine in modulating both structure and function of the human renal proximal tubule. …”
Get full text

Proinflammatory Cytokines Trigger the Onset of Retinal Abnormalities and Metabolic Dysregulation in a Hyperglycemic Mouse Model by Gaganashree Shivashankar, Julie C. Lim, Monica L. Acosta

“…To further understand and validate the metabolic biomarkers of DR, we investigated the effect of intravitreal proinflammatory cytokines on the retinal structure, function, and metabolism in an in vivo hyperglycemic mouse model. …”
Get full text

Dysfunctional large-scale brain networks in drug-naïve depersonalization-derealization disorder patients by Sisi Zheng, Mingkang Song, Nan Song, Hong Zhu, Xue Li, Dongqing Yin, Shanshan Liu, Yan Zhao, Meng Fang, Yanzhe Ning, Hongxiao Jia

“…Several neuroimaging studies have revealed altered brain function and structure in DPRD. However, the knowledge about large-scale dysfunctional brain networks in DPRD remains unknown. …”
Get full text

Efficacy of Hongjing I granule, an herbal medicine, in patients with mild to moderate erectile dysfunction in a randomized controlled trial by Run-Nan Xu, Run-Nan Xu, Jun Guo, Chun-He Zhang, Qing Zhou, Qiang Gen, Qiang Gen, Fu Wang, Yu Zhao, Yu Zhao, Xin-Yun Luo, Yan-Feng Li, Yi-Jia Fu, Yi-Jia Fu, Xin Zhang, Xin Zhang, Wen-Zhi Wang, Jian-Xiong Ma, Jian Wang, Jian Wang, Xiao-Jun Huang, Wen-Jie Huang, Bo-Dong Lv, Bo-Dong Lv

“…Primary outcome measures encompass the International Index of Erectile Function-Erectile Function domain (IIEF-EF) score, the Sexual Encounter Profile (SEP), and scores derived from the traditional Chinese medicine symptom evaluation.ResultsOf the 122 men enrolled, the baseline IIEF-EF score averaged 16.00 [IQR: 13.00, 18.00]. …”
Get full text

The Role of Adipokines in Spinal Disease: A Narrative Review by Jake M. McDonnell, Stacey Darwish, Joseph S. Butler, Conor T. Buckley

“…Their diverse functions in both structural and metabolic regulation highlight their potential as both biomarkers and therapeutic targets. …”
Get full text

FEATURES OF IMPLEMENTATION OF MANAGEMENT INNOVATIONS BY IT ENTREPRENEURS by Stanislav A. Horbachenko

“…The main management innovations used by IT companies in Ukraine are analyzed: quality management, controlling, reengineering, system intervention strategy, neural network technologies, information-associative modeling, structural-functional modeling, etc. …”
Get full text

Assessing the cumulative effects of nearshore habitat restoration actions for multiple populations of juvenile salmon in Whidbey Basin, Washington: foundation and approach for synt... by Kathryn L. Sobocinski, Michael LeMoine, Joshua W. Chamberlin, Letitia Conway-Cranos, Annelise Del Rio, Heida L. Diefenderfer, Heida L. Diefenderfer, Correigh M. Greene, Jason Hall, Gary E. Johnson, Ronald M. Thom, Elene Trujillo, Todd Zackey

“…Ecosystem restoration is a common tool for re-establishing ecosystem processes, structures, and functions to improve biodiversity and services in coastal and estuarine ecosystems. …”
Get full text

Bleeding and thrombotic complications during treatment with direct oral anticoagulants or vitamin K antagonists in venous thromboembolic patients included in the prospective, obser... by Daniela Poli, Emilia Antonucci, Vittorio Pengo, Niccolò Maggini, Sophie Testa, Antonio Insana, Carmelo Paparo, Pasquale Pignatelli, Gualtiero Palareti, Paolo Prandoni, Elvira Grandone, Cristina Legnani, Daniela Mastroiacovo, Alberto Tosetto, Walter Ageno, Rossella Marcucci, Oriana Paoletti, Giovanna Colombo, Benilde Cosmi, Giuliana Guazzaloca, Ludovica Migliaccio, Anna Falanga, Teresa Lerede, Luca Barcella, Gentian Denas, Elisa Bison, Lucia Ruocco, Paolo Chiarugi, Giuliana Martini, Simona Pedrini, Federica Bertola, Lucilla Masciocco, Pasquale Saracino, Angelo Benvenuto, Claudio Vasselli, Marco Marzolo, Antonietta Piana, Francesco Cibecchini, Andrea Toma, Pietro Barbera, Donatella Colaizzo, Domizio Serra, Daniele Pastori, Serena Rupoli, Giuseppe Malcangi, Giovanni Nante, Rosella Sangiorgio

“…The prevalence of symptomatic PE and impaired renal function was higher in patients receiving VKAs. Duration of anticoagulation was &gt;180 days in approximately 70% of patients. …”
Get full text

Development of a medication literacy assessment scale for patients with mental disorders in recovery in China: a mixed-methods Delphi study by Lin Deng, Bei Wu, Jianlin Lou, Jianlin Lou, Chen Zhang, An Huang, An Gu, Haiqin Chen, Lina Wang

“…Preliminary items were generated through a comprehensive literature review and semi-structured interviews with 20 patients and 6 psychiatric professionals. …”
Get full text

A Proposed Diagnostic and Treatment Algorithm for the Management of Lumbar Discogenic Pain by Lorio MP, Beall DP, Myers TJ, Naidu RK, McRoberts WP, Davis TT, Gage EG, Calodney AK, Verrills P, De Palma MJ, Amirdelfan K, Block JE

“…., Walnut Creek, CA, USA; 12Private Practice, San Francisco, CA, USACorrespondence: Jon E Block, Private Practice, 2210 Jackson Street, Ste. 401, San Francisco, CA, 94115, USA, Tel +1 415-775-7947, Email jb@drjonblock.comBackground: There is renewed interest in the intervertebral disc as a target for treatments aimed at ameliorating lumbar discogenic pain by restoring and preserving the natural structure and function of this component of the vertebral motion segment.Methods: Using a modified Delphi methodology involving a panel of 11 experts, we developed a simple, understandable clinical algorithm to serve as a foundation for objective decision making regarding the diagnosis and treatment of lumbar discogenic pain throughout the entire continuum of care. …”
Get full text

Female Anopheles Mosquito Gut Microbiota: Description and Impact on Transmission of Plasmodium Parasite by Salisu, H. L., Yayo, A. M., Sharif, A. A., Dambatta, A. S.

“…Key focus areas include the structure and diversity of Anopheles gut microbiota, their immunomodulatory functions, interactions with P. falciparum, and potential applications in paratransgenesis and biological vector control.  …”
Get full text