Nuclear pore complex protein RANBP2 and related SUMOylation in solid malignancies by Xinning Yu, Huatao Wu, Zheng Wu, Yangzheng Lan, Wenjia Chen, Bingxuan Wu, Yu Deng, Jing Liu

“…SUMO E3 ligases are pivotal in this process, exhibiting diverse functionalities through structural domains and subcellular localizations. …”
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Injectable ion-coordinated double-network conductive hydrogel for spinal cord injury repair by Huan Yu, Fan Liu, Yaorui Hu, Yaorui Hu, Yaorui Hu, Weikang Wan, Weikang Wan, Weikang Wan, Qing Liu, Qing Liu, Qing Liu, Shuai Zhou, Luping Zhang, Liming Li, Fei Huang

“…They are not enough to promote neural regeneration and functional recovery. There is an urgent need to develop novel therapeutic approaches to overcome this challenge. …”
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Acute pyelonephritis complicated by subcapsular and perinephric hematoma: Diagnostic role of CT scan and 6-month follow-up by Maryam Shahali Ramsheh, MD, Reza Zahedpasha, MD, Amin Ghaemi Amiri, Fereshte Maghsoudlou, MD

“…Acute pyelonephritis is a common renal infection that can become life-threatening when complicated by structural abnormalities, resistant pathogens, or systemic comorbidities such as diabetes mellitus. …”
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A rapid onset of Guillain–Barre syndrome following spinal anesthesia for knee arthroscopy: a case report by Amin Ahmed Kapadia, Lena Koshy, Usman Ali, Salil Gupta, Hammad Naqi Khan

“…By discharge, the patient had regained full motor and sensory function and achieved complete recovery at 6 months follow-up. …”
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The Causal Relationship Between Asthma and Hippocampal Volume: A Study Based on Bidirectional Mendelian Randomization Analysis by Dandan Han, Shaohua Zhao

“…While observational studies suggest that asthma may affect hippocampal structure and function through mechanisms such as chronic inflammation and hypoxia, its causal relationship remains unclear. …”
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Treatment of Denervated Muscle Atrophy by Injectable Dual‐Responsive Hydrogels Loaded with Extracellular Vesicles by Ziheng Bu, Jianxing Jing, Wei Liu, Zhen Fan, Junchao Huang, Zheng Zhou, Jianhai Hu, Jinxi An, Jiachang Hong, Jianing Yu, Daolin Tang, Min Sun, Jianzhong Du, Peng Wu

“…This platform presents a novel therapeutic approach by maintaining EV bioactivity, enabling tunable release based on the disease state, and facilitating the restoration of muscle structure and function.…”
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Sex differences in schizophrenia: symptomatology, treatment efficacy and adverse effects by Ivi Moniem, Vasilios Kafetzopoulos

“…Men typically experience illness onset approximately 3–5 years earlier than women, with more severe negative symptoms, worse social functioning, and higher rates of comorbid substance use disorders. …”
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Undervalued essential work and lacking health literacy as determinants of COVID-19 infection risks: a qualitative interview study among foreign-born workers in Sweden by Annika Rosengren, Kristina Jakobsson, Mia Söderberg, Maria Magnusson, Juhaina Swaid

“…The respondents fulfilled important societal functions, but their work was undervalued due to low job status, and they had little influence on improving safety at work. …”
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The translational power of Alzheimer’s-based organoid models in personalized medicine: an integrated biological and digital approach embodying patient clinical history by Cristina Dolciotti, Marco Righi, Eleonora Grecu, Marcello Trucas, Cristina Maxia, Daniela Murtas, Andrea Diana

“…BOs derived from patient-specific induced pluripotent stem cells (iPSCs) mimic the structural and functional complexities of the human brain. …”
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Social support and depression among community dwelling older adults in Asia: a systematic review by Tengku Amatullah Madeehah Tengku Mohd, Raudah Mohd Yunus, Farizah Hairi, Noran N Hairi, Wan Yuen Choo

“…Social support was found to be measured by multiple components, most commonly through a combination of structural and functional constructs. Perceived social support is more commonly measured compared with received social support. …”
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Cardiomyopathies and a brief insight into DOX-induced cardiomyopathy by Sampat Singh Tanwar, Sumeet Dwivedi, Sheema Khan, Seema Sharma

“…Abstract Background Cardiomyopathy is a heterogeneous group of myocardial disorders characterized by structural and functional abnormalities of the heart muscle. …”
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A Framework for Healthcare Provision to Children with Intellectual Disability by Anish TS, Vijayakumar K, Anilkumar TV, Zinia T Nujum, Hisham Moosan

“…The objectives of this study were to evaluate the structure and functioning of ‘Buds’ schools, to identify the healthcare needs of the students, and to conceptualise a framework for healthcare provision.…”
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Surgical implants in animal models for male and female infertility: A translational approach by S. Bharath, A.S. Vickram, B. Bhavani Sowndharya, C. Prasanth, D. Jenila Rani, G. Gulothungan, Hitesh Chopra, Tabarak Malik

“…Structured Abstract: Background: Infertility remains a significant challenge in reproductive medicine, affecting both men and women. …”
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Striving to integrate self-management into daily life: a qualitative meta-synthesis of the perspectives and experiences from head and neck cancer survivors by Hao Zhang, Li Yin, Qing Yang, Aiping Wang, Linyu Xu, Jianxia Lyu

“…This integration revealed 3 primary themes and 10 subthemes, specifically: (1) the management of disease-related and treatment-related symptoms and functional alterations in HNC, exploring self-management strategies such as coping with and monitoring physical and mental symptoms and adjusting to modifications in fundamental operations; (2) barriers and facilitators in the integration process of self-management, including psychological, emotional and cognitive disorders, the impact of symptom burden on patients’ motivation and capacity for self-management, structural impediments and facilitators; and (3) challenges in incorporating self-management into daily life and strategies for effective implementation, encompassing acceptance and adaptation as strategies for coping and thriving, proactive issue resolution, self-motivation and the employment of a diverse array of targeted strategies emphasising recovery.Conclusions Patients diagnosed with HNC must engage in extensive self-management throughout diagnosis and treatment, encountering numerous challenges when integrating self-management practices into their daily lives. …”
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Immunotherapy targeting isoDGR‐protein damage extends lifespan in a mouse model of protein deamidation by Pazhanichamy Kalailingam, Khalilatul‐Hanisah Mohd‐Kahliab, SoFong Cam Ngan, Ranjith Iyappan, Evelin Melekh, Tian Lu, Gan Wei Zien, Bhargy Sharma, Tiannan Guo, Adam J MacNeil, Rebecca EK MacPherson, Evangelia Litsa Tsiani, Deborah D O'Leary, Kah Leong Lim, I Hsin Su, Yong‐Gui Gao, A Mark Richards, Raj N Kalaria, Christopher P Chen, Neil E McCarthy, Siu Kwan Sze

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Age-related disturbances in rest-activity rhythms and integrity of the hippocampal network: An exploratory study by Aurore Jouvencel, Bixente Dilharreguy, Marion Baillet, Karine Pérès, Jean-François Dartigues, Hélène Amieva, Willy Mayo, Gwenaëlle Catheline

“…A segmentation of the hippocampus and its related structures was used to assess volumes and functional connectivity in this network based on anatomical and resting state functional data. …”
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IL-1 Superfamily Across 400+ Species: Therapeutic Targets and Disease Implications by Weibin Wang, Dawei Li, Kaiyong Luo, Baozheng Chen, Tingting Hao, Xuzhen Li, Dazhong Guo, Yang Dong, Ya Ning

“…In addition to advancing our knowledge of the function of the IL-1 family in autoimmune, inflammatory, and carcinogenic illnesses, this research lays the groundwork for the development of more potent targeted therapeutics by creating an evolutionary framework for the IL-1 family.…”
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Probiotics in Sports: Modulating the Microbiome for Performance and Health by Katarzyna Moliszewska, Paweł Kukiełka, Joanna Kośka, Gabriela Łocik, Julia Mazurek, Julia Załęcka, Alicja Nowik, Kacper Dywan, Martyna Musiorska, Michał Błaszkiewicz

“…ConclusionsThe gut microbiome is a key determinant of systemic health. Targeted diet, structured physical activity, and personalized probiotic use can optimize microbiota function. …”
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Immunometabolism in the Aging Heart by Kranti A. Mapuskar, Barry London, Zeb R. Zacharias, Jon C.D. Houtman, Bryan G. Allen

“…Structural, functional, and molecular‐level changes in the aging heart are influenced by a dynamic interplay between immune signaling and cellular metabolism that is referred to as immunometabolism. …”
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A literature review on role of physical activity in the prevention and treatment of depression by Albert Lompart, Michał Wabiszewicz, Albert Kosarewicz, Łukasz Woźniak, Patrycja Krysiak

“…It critically assesses recent evidence and identifies the most effective exercise interventions by systematically analysing studies published between 2017 and 2025. …”
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