Contributions of mechanical loading and hormonal changes to eccentric hypertrophy during volume overload: A Bayesian analysis using logic-based network models. by Johane H Bracamonte, Lionel Watkins, Betty Pat, Louis J Dell'Italia, Jeffrey J Saucerman, Jeffrey W Holmes

“…We believe this represents a promising approach to using the known structure of an intracellular signaling network to integrate information from multiple studies into quantitative predictions of the range of expected responses to potential interventions in the complex setting of cardiac hypertrophy driven by a combination of hormonal and mechanical factors.…”
Get full text

Bivariate Copula Model on Fitting Correlated Time-to-Event Outcomes: Age at First Sex and Age at First Marriage Among Youth in Tanzania by Jacqueline Materu, Eveline T. Konje, Ties Boerma, Mark Urassa, Milly Marston, Jim Todd

“…This approach can inform targeted interventions to improve youth health outcomes.…”
Get full text

Assessment of the Prevalence of the Use of Nasal Decongestants Among Hail Population by Farida Habib Khan, Abdullah D Alotaibi, Amal Daher Alshammari, Mohammed Alateeq, Muath Alshmmari, Read Alharbi, Rakhi Issrani

“…Background: Nasal decongestants are widely used to relieve nasal congestion caused by conditions such as allergic rhinitis, sinusitis, and the common cold. These medications function by constricting nasal blood vessels, reducing swelling, and improving airflow. …”
Get full text

Effect of Subtalar Joint Mobilization and Myofascial Trigger Point Release on Pain and Disability in Plantar Fasciitis by Prerana S Prakash, Paul Daniel VK, Pruthviraj R, Anusha V Shenai

“…The fascias role in stabilizing body structures is vital for addressing this condition. Myofascial Trigger Point Release MTrP has recently shown promise in reducing pain and improving function.Aim and Objectives This study evaluates the impact of subtalar joint mobilization and MTrP alongside conventional therapy on pain and disability in plantar fasciitis patients and compares their effectiveness.Methods After IEC approval from RV College of Physiotherapy participants were screened using the windlass test and divided into two groups. …”
Get full text

Perspectives of family medicine residents on artificial intelligence for survival estimation in patients with serious illness. by Gemma Postill, Anglin Dent, Jill Dombroski, Amol A Verma, Jeff Myers, Tavis Apramian

“…In addition to survival, pertinent challenges to address with AI include understanding of expected function, maximizing quality of life, and response to interventions, in addition to quantifying survival time. …”
Get full text

Combined exercise and Hawthorn protect against learning impairments and hippocampal damage from trimethyltin neurotoxicity in rat by Maryam Keshvari, Ali Heidarianpour, Farzaneh Chehelcheraghi

“…The superiority of the endurance and resistance training combination with hawthorn oral consumption than the unit implementation of these interventions was achieved in reducing the negative changes in the structure and the hippocampus function of neurotoxicity rats through increasing the neurotrophins levels and cholinergic modulation.…”
Get full text

I’m still quite young: women’s lived experience of precocious or premature menopause: a qualitative study among Egyptian women by Yasmine M. Osman, Hend Reda Ali El-Kest, Majed Awad Alanazi, Mostafa Shaban

“…Abstract Background Precocious menopause, the cessation of ovarian function before age 40, presents complex physical, emotional, and socio-cultural challenges. …”
Get full text

Update of the sideroflexin (SLC56) gene family by Angeliki I. Katsafadou, Daniel W. Nebert, Sergey A. Krupenko, David C. Thompson, Vasilis Vasiliou

“…Structurally, SFXNs share conserved transmembrane domains and key motifs critical for substrate transport, mitochondrial iron homeostasis, and overall mitochondrial function. …”
Get full text

Pharmacological and therapeutic effects of natural products on liver regeneration-a comprehensive research by Chang Tian, Yuhan Wang, Ran Wang, Linxin Pan, Tao Xu

“…Abstract Liver regeneration (LR) refers to the physiological process by which hepatocytes undergo cellular proliferation to restore the structure and function of the liver following significant hepatocyte loss due to injury or partial hepatectomy (PH). …”
Get full text

Efficiency and Applicability of Virtual Surgical Planning in Maxillofacial and Mandibular Bone Reconstruction: A Narrative Review by Mohammed Mahmoud Shalabi, Khaldoun M. A. Darwich, Mohammad Naem Kheshfeh, Mohammad Younis Hajeer

“…<b>Background:</b> Facial structures are critical to aesthetics and function. …”
Get full text

REHABILITATION AND HEALTH-RELATED QUALITY OF LIFE AND FATIGUE IN PATIENTS WITH LUNG CANCER - EFFECTS OF EXERCISE by Morten Quist

“…While no signifcant differences in aerobic capacity(VO2peak) were observed between the groups, both demonstrated improvements in physical function and emotional well-being. Notably, early rehabilitation led to a smaller initial decline in VO2peak and continuous improvements in HRQoL up to 26 weeks post-surgery, supporting early intervention to alleviate lung cancer-related symptoms and fatigue. …”
Get full text

Relational coordination and team‐based care: Change initiative overload and other challenges in a learning health system by Lauren Hajjar, Olawale Olaleye, Julius Yang, Susan McGirr, Erin E. Sullivan

“…This study aims to (1) understand how relational interventions including shared huddles and cross‐role shadowing opportunities, impact team dynamics and functioning and (2) describe the challenges and opportunities associated with implementing relational interventions at an Academic Medical Center in a large metropolitan city in the United States. …”
Get full text

A Qualitative Study Examining the Unintended Consequences from Implementing a Case Management Team to Reduce Avoidable Hospital Readmission in Singapore by Shilpa Surendran, Stephen So, Toon Wei Lim, David Bruce Matchar

“…Methods: We conducted five in-depth semi-structured interviews with stakeholders who were involved in the planning, development, and implementation of the intervention in addition to analysing 12 intervention documents. …”
Get full text

Health program for prEvention of cardiovascuLar disEases based on a risk screeNing strategy with Ankle-brachial index: HELENA study protocol by Gina Domínguez-Armengol, Gina Domínguez-Armengol, Francesc Ribas-Aulinas, Francesc Ribas-Aulinas, Elisabet Balló, Maite Alzamora-Sas, Maite Alzamora-Sas, Mar Serrat-Costa, Anna Ruiz-Comellas, Anna Ruiz-Comellas, Anna Ruiz-Comellas, Maria Jose Forcadell-Peris, Maria Jose Forcadell-Peris, Pere Toran, Ruth Martí-Lluch, Ruth Martí-Lluch, Ruth Martí-Lluch, Anna Ponjoan, Anna Ponjoan, Anna Ponjoan, Jordi Blanch, Lia Alves-Cabratosa, Lluís Zacarías-Pons, Lluís Zacarías-Pons, Eric Tornabell-Noguera, Eric Tornabell-Noguera, Álvaro Sánchez-Pérez, Álvaro Sánchez-Pérez, Anna Berenguera-Ossó, Anna Berenguera-Ossó, Rafel Ramos, Rafel Ramos, Rafel Ramos, Rafel Ramos, Rafel Ramos, The HELENA Study Group

“…IntroductionThe use of risk functions to individualize preventive interventions is a key strategy in the primary prevention of coronary heart diseases (CHD). …”
Get full text

Hsp70: A Multifunctional Chaperone in Maintaining Proteostasis and Its Implications in Human Disease by Manish Kumar Singh, Sunhee Han, Songhyun Ju, Jyotsna S. Ranbhise, Joohun Ha, Seung Geun Yeo, Sung Soo Kim, Insug Kang

“…This review highlights the structural and functional importance of Hsp70, explores its role in disease pathogenesis, and discusses its potential in diagnostic and therapeutic applications.…”
Get full text

Care-related quality of life of informal caregivers of stroke survivors: Cross-sectional analysis of a randomized clinical trial. by Lorena Villa-García, Mercè Salvat-Plana, John Slof, Natalia Pérez de la Ossa, Sònia Abilleira, Marc Ribó, Verónica Hidalgo-Benítez, Marco Inzitari, Aida Ribera

“…<h4>Purpose</h4>We aimed to describe the intensity of care and its consequences on informal caregivers of stroke survivors according to the degree of care receivers' functional dependence for activities of daily living; and to identify the factors associated with caregivers' care-related quality of life.…”
Get full text

Integrating Social Network and Space Syntax: A Multi-Scale Diagnostic–Optimization Framework for Public Space Optimization in Nomadic Heritage Villages of Xinjiang by Hao Liu, Rouziahong Paerhati, Nurimaimaiti Tuluxun, Saierjiang Halike, Cong Wang, Huandi Yan

“…Linear villages demonstrate weak systemic linkages, requiring “segment-connection point supplementation” interventions to mitigate structural elongation. Dispersed villages maintain moderate network density but face challenges in visual integration and centrality, demanding targeted activation of key intersections to improve regional cohesion. …”
Get full text

Cervicogenic Headache and Physiotherapy: A Systematic Review of Treatment Modalities by Manali Sanket Chitlange, Pallavi Harjpal

“…Techniques aim to improve joint function, reduce muscle tension, and enhance cervical stability. …”
Get full text

Bioactive compounds in fermented foods: a systematic narrative review by İbrahim Ender Künili, Vildan Akdeniz, Aslı Akpınar, Şebnem Öztürkoğlu Budak, José Antonio Curiel, Mustafa Guzel, Cem Karagözlü, Muzeyyen Berkel Kasikci, Grech Perry Mario Caruana, Małgorzata Starowicz, Christèle Humblot, Erhan Keyvan, Christophe Chassard, Smilja Pracer, Guy Vergères, Harun Kesenkaş

“…Findings were summarised in “Population, Intervention, Comparator, Outcome” (PICO)-structured tables and classified by health domain. …”
Get full text

A novel neuroimaging based early detection framework for alzheimer disease using deep learning by Areej Alasiry, Khlood Shinan, Abeer Abdullah Alsadhan, Hanan E. Alhazmi, Fatmah Alanazi, M. Usman Ashraf, Taseer Muhammad

“…Comparative analyses further validate the superiority of NEDA-DL over existing methods. By integrating structural and functional neuroimaging insights, this approach enhances diagnostic precision and supports clinical decision-making in Alzheimer’s disease detection.…”
Get full text