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1041
Exploring Virtual Reality-Based Reminiscence Therapy on Cognitive and Emotional Well-Being in People with Cognitive Impairments: A Scoping Review
Published 2025-05-01“…Studies suggest that VR-based interventions improve mood, reduce apathy, and enhance emotional engagement, making VR a valuable tool for cognitive and emotional support. …”
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1042
Treatment Modalities for Aromatase Inhibitor-Associated Musculoskeletal Syndrome (AIMSS): A Scoping Review of Prospective Treatment Studies
Published 2025-04-01“…Online databases were searched (from inception to January 8, 2025) to identify 74 reports from prospective studies of interventions for AIMSS pain, stiffness, or interference with functioning. …”
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1043
Molecular constraints of sarcopenia in the ageing muscle
Published 2025-07-01“…Skeletal muscle comprises multinucleated fibers supported by satellite cells—muscle stem cells essential for repair and regeneration. With age, both the structure and function of these components deteriorate: myonuclei become disorganized, gene expression skews toward catabolic, inflammatory, and fibrotic pathways, and satellite cell numbers and activity decline. …”
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1044
Research progress in predicting the conversion from mild cognitive impairment to Alzheimer’s disease via multimodal MRI and artificial intelligence
Published 2025-06-01“…Multimodal magnetic resonance imaging (MRI) techniques (including structural MRI, functional MRI, and cerebral perfusion MRI) can yield information on the morphology, structure, and function of the brain from multiple dimensions, providing a key basis for revealing the pathophysiological mechanisms during the conversion from MCI to AD. …”
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1045
Radiation Retinopathy: Microangiopathy-Inflammation-Neurodegeneration
Published 2025-02-01“…Methods: We performed a proton beam irradiation of 5–15 Cobalt-Gray-Equivalent (CGE) of the eyes of female C57Bl6/J (Cx3cr1<sup>+/+</sup>), Cx3cr1<sup>gfp/+</sup> and Cx3cr1<sup>gfp/gfp</sup> mice mimicking the clinical situation and evaluated the structure, function and cellular composition of the retina up to 24 weeks after irradiation. …”
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1046
Advancements in lung regeneration: from bench to bedside
Published 2025-02-01“…From stem cell and cell-based therapies to the utilization of biological and synthetic materials, as well as the strategic deployment of growth factors, a diverse array of strategies is being explored to rejuvenate lung function. By critical analysis of in vitro, preclinical, and clinical studies, this review aims to provide a comprehensive overview of the emerging technology of lung regeneration research, shedding light on promising avenues for future therapeutic interventions.…”
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1047
Determination of the molecular basis for a limited dimorphism, N417K, in the Plasmodium vivax Duffy-binding protein.
Published 2011-01-01“…Successful vaccine development necessitates a deeper understanding of the role of these polymorphisms in both parasite function and evasion of host immunity. A 3D structure of the homologous P. knowlesi DBP predicts that most variant residues are surface-exposed, including N417K, which is a dimorphic residue change that has previously been shown to be part of a linked haplotype that alters DBP sensitivity to inhibitory antibody. …”
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1048
Network Pharmacology Approaches to Myocardial Infarction Reperfusion Injury: Exploring Mechanisms, Pathophysiology, and Novel Therapies
Published 2025-06-01“…Post-reperfusion recovery is further complicated by structural and functional abnormalities such as microvascular obstruction, endothelial dysfunction, and myocardial stunning. …”
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1049
Enduring Neurobiological Consequences of Early-Life Stress: Insights from Rodent Behavioral Paradigms
Published 2024-09-01“…These stressors can induce long-lasting changes in brain structure and function, impacting areas involved in emotion regulation, cognition, and stress response. …”
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1050
Human, or nature-led? A spectrum of nature-based solutions
Published 2025-12-01“…Based on our research in water resources, landscape management, and climate mitigation, in this perspective piece we identify two forms of NbS: (1) human-led interventions (HNbS) that are actively designed and maintained, and (2) nature-led solutions (NNbS) that allow natural processes to function with minimal human intervention.Drawing on our experience working with practitioners and policymakers, we highlight four key factors influencing the uptake and implementation of HNbS and NNbS: (1) the need for certainty, (2) balancing co-benefits and risks, (3) governance structures, and (4) societal perceptions of NbS.We propose that viewing NbS on a spectrum—from human-led to nature-led—offers a valuable framework for integrating these approaches alongside engineered solutions in policy and management. …”
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1051
Emotional distress and well-being among people with motor neurone disease (MND) and their family caregivers: a qualitative interview study
Published 2021-08-01“…Participants described the emotional distress of losing physical function and having a threatened future because of poor prognosis. …”
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1052
Alzheimer’s disease pathogenesis: standing at the crossroad of lipid metabolism and immune response
Published 2025-06-01“…Lipid metabolism plays a critical role in maintaining cell membrane structure and function, regulating the production and clearance of Aβ, and supplying energy to the brain. …”
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1053
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1054
Diabetic pregnancy: A literature review of maternal and neonatal adverse outcomes
Published 2025-04-01“…Pregnant patients with diabetes also have an increased risk of pre-eclampsia, likely due to complications related to abnormal structure and function of the placenta. In addition, cardiovascular complications are more common and may present antepartum, intrapartum, or postpartum. …”
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1055
A review of the 661W cell line as a tool to facilitate treatment development for retinal diseases
Published 2025-04-01“…Abstract Retinal diseases encompass a diverse group of disorders that affect the structure and function of the retina, leading to visual impairment and, in some cases, irreversible vision loss. …”
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1056
Principles of diet therapy for sarcopenic obesity: A review
Published 2025-01-01“…In elderly patients with SO, a reduction in body weight impacts not only the muscle mass but also muscle function. A promising approach to diet therapy for this type of obesity is qualitative modification of the diet structure used for weight loss. …”
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1057
Conservative treatment of older adult patients with shoulder diseases: a narrative review
Published 2025-01-01“…Platelet-rich plasma is a regenerative option that may improve tendon healing, but mixed findings highlight the need for further investigation. A structured physical therapy program focusing on range of motion and strengthening is essential, with alternative interventions used judiciously. …”
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1058
Comprehensive evaluation of clinical, echocardiographic, and CMR findings in dilated cardiomyopathy
Published 2025-01-01“…Accurate diagnosis and risk stratification are critical for optimal management, with advanced imaging playing a key role in assessing myocardial structure and function. Materials and Methods: This cross-sectional study included 75 patients diagnosed with DCM at a tertiary care center between July 2022 and July 2024. …”
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1059
Assessment of the Knowledge and Use of Ultrasound in Diagnosing Sarcopenia among Healthcare Workers in Southeast Nigeria
Published 2025-07-01“…Background: Sarcopenia results in a reduction in function, falls, frailty, and increased morbidity and mortality. …”
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1060
Sustained immune activation and impaired epithelial barrier integrity in the ectocervix of women with chronic HIV infection.
Published 2024-11-01“…Conversely, genes and pathways associated with epithelial barrier function and structure were downregulated in the context of HIV. …”
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