How health mediation can function effectively on the fostering of healthcare utilization? : a realist qualitative study by Elodie Richard, Leila Ramiz, Mara Oltean, Vanina Troussier, Caroline Ulracher, Olivia Speed, Muriele Conort, Cécile Coutant, Fréderique Chaves Quirino, Judith Martin Fernandez, Stéphanie Vandentorren, Linda Cambon

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Depressive and Negative Symptoms in the Early and Established Stages of Schizophrenia: Integrating Structural Brain Alterations, Cognitive Performance, and Plasma Interleukin 6 Lev... by Fabiana Corsi-Zuelli, Gary Donohoe, Siân Lowri Griffiths, Cristina M. Del-Ben, Andrew J. Watson, Tom Burke, Paris A. Lalousis, Declan McKernan, Derek Morris, John Kelly, Colm McDonald, Saahithh R. Patlola, Carmine Pariante, Nicholas M. Barnes, Golam M. Khandaker, John Suckling, Bill Deakin, Rachel Upthegrove, Maria R. Dauvermann

“…Background: Depressive and negative symptoms are related to poor functional outcomes in schizophrenia. Cognitive deficits, reduced brain cortical thickness and volumes, and inflammation may contribute to depressive and negative symptoms, but pharmacological treatment and disease progression may confound the associations. …”
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Psychometric properties of the Lithuanian version of the functionality appreciation scale by Migle Baceviciene, Vaiva Balciuniene, Rasa Jankauskiene

“…The Lithuanian version of FAS is a psychometrically sound measure of body functionality appreciation. FAS might contribute to a comprehensive assessment of positive body image and can be used in various interventions.…”
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Acceptability of the content and functionality of a just-in-time adaptive intervention for gambling problems: a mixed-methods evaluation of gambling habit hacker by S. N. Rodda, S. S. Merkouris, C. J. Greenwood, A. C. Thomas, D. I. Lubman, N. A. Dowling

“…This mixed-methods study evaluated the acceptability of a JITAI called Gambling Habit Hacker, focusing on both the app’s content and functionality. Methods Australian participants who had recently completed a micro-randomized trial of the app provided feedback through semi-structured interviews. …”
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Efficacy of psychosocial interventions on social functioning in individuals with childhood maltreatment experiences: a protocol for a systematic review and network meta-analysis by Natalia E. Fares-Otero, Silvia Amoretti, Brisa Solé, Sarah L. Halligan, Eduard Vieta, Stefan Leucht, Soraya Seedat, Mathias Harrer

“…Background: Several psychosocial interventions have shown promising effects in treating people affected by childhood maltreatment (CM); however, their comparative efficacy on social functioning remains largely unknown. …”
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Bioinformatics analysis to investigate the potential relationship between mitochondrial structure and function-related genes and the immune microenvironment in atherosclerosis by Hanning Yang, Yue Sun, Shumin Li, Yueyue Tang, Yuxue Wang, Yunyan Li, Yongping Lu

“…ObjectiveThis study aims to elucidate the interactions between genes associated with mitochondrial structure and function and the immune microenvironment in atherosclerosis.MethodsDifferentially expressed mitochondria-related genes (DE-MRGs) were identified through the analysis of two gene expression datasets, GSE100927 and GSE159677, in conjunction with a list of mitochondria-related genes sourced from the MitoCarta3.0 database. …”
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An integrative analysis of functional consequences of PKD2 missense variants on RNA and protein structures: a computational approach by Chandra Devi, Prashant Ranjan, Parimal Das

“…Abstract Background The PKD2, encoding polycystin-2 (PC2) protein, is second major genetic determinant of autosomal dominant polycystic kidney disease (ADPKD) after PKD1. However, the structural and functional consequences of genetic variants in PKD2 remain poorly understood. …”
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In-depth insight into tumor-infiltrating stromal cells linked to tertiary lymphoid structures and their prospective function in cancer immunotherapy by Maedeh Radandish, Niloofar Mashhadi, Amir Hossein Aghayan, Motahareh Taghizadeh, Sara Salehianfard, Sheida Yahyazadeh, Omid Vakili, Somayeh Igder

“…Furthermore, it highlights the dual functional roles of TLSs as sites of both anti-tumor immune activation and immunosuppression, notably via the enrichment of regulatory T cells. …”
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Psychological resources and interventions for teachers’ emotional competence and well-being: a systematic review by Brenda Cervellione, Ester Maria Concetta Lombardo, Calogero Iacolino

“…However, methodological heterogeneity, limited use of longitudinal designs, and variation in outcome measures constrained generalizability.DiscussionFindings underscore the importance of promoting psychological resources and structured interventions to support teachers’ emotional well-being and professional sustainability. …”
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Structured prenatal yoga on endothelial function in high-risk preeclampsia of pregnant women focusing on ET-1/NO ratio by Hamimatus Zainiyah, Bambang Purwanto, Ernawati Ernawati, Raden Argarini, Mukhoirotin Mukhoirotin

“…Prenatal yoga may improve endothelial function by enhancing blood flow and cardiovascular regulation Objective: This study aimed to evaluate the effect of a structured prenatal yoga program on the ET-1/NO ratio in pregnant women at high risk of developing preeclampsia. …”
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Novel Structure–Function Models for Estimating Retinal Ganglion Cell Count Using Pattern Electroretinography in Glaucoma Suspects by Andrew Tirsi, Isabella Tello, Timothy Foster, Rushil Kumbhani, Nicholas Leung, Samuel Potash, Derek Orshan, Celso Tello

“…<b>Background/Objectives</b>: The early detection of retinal ganglion cell (RGC) dysfunction is critical for timely intervention in glaucoma suspects (GSs). The combined structure–function index (CSFI), which uses visual field and optical coherence tomography (OCT) data to estimate RGC counts, may be of limited utility in GSs. …”
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Effectiveness of Structural Couple Therapy and Intensive Short-Term Dynamic Psychotherapy on Intrapersonal-Interpersonal Skills and Family Function in Couples by Nayereh Sadat Sadatmand, Ozra Etemadi, Fatemeh Bahrami, Maryam Fatehizadeh

“…Objective: The current investigation sought to evaluate the efficacy of structural couple therapy in conjunction with Intensive Short-Term Dynamic Psychotherapy (ISTDP) regarding the enhancement of intrapersonal-interpersonal skills and family function of couples. …”
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Transcutaneous auricular vagus nerve stimulation enhances structural and functional remodeling in sensorimotor networks following intracerebral hemorrhage in rats by Jun Zhang, Zengyu Zhang, Lichao Wei, Dewen Ru, Meihua Wang, Pengfei Fu, Weijian Yang, Gang Wu, Lei Yang, Caihua Xi, Xiangru Ye, Yuwen Zhang, He Wang, Jin Hu, Qiang Yuan

“…Abstract Background Intracerebral hemorrhage (ICH) leads to severe neurological deficits by disrupting brain structure and function, particularly in the sensorimotor cortex. …”
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Effects of remote Baduanjin Qigong intervention on quality of life and physical function in patients with mild to moderate Parkinson’s disease: a protocol of randomized controlled... by Jizhe Yu, Yi Jia, Guanglin Ma, Dong Wang, Zhen Zhang, Zengbao An, Yingkui Li

“…BackgroundThis study aims to evaluate the effects of remote Baduanjin Qigong intervention on the quality of life and physical function in patients with mild to moderate Parkinson’s disease (PD) through a randomized controlled trial (RCT) and to compare its efficacy with conventional exercise rehabilitation.Methods/designThis RCT will enroll participants who, following baseline assessments and physical function tests, will be randomly allocated into one of three groups: the Qigong group (QG), the conventional exercise rehabilitation group (EG), or the control group (CG). …”
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Circuit training intervention for cognitive function, gut microbiota, and aging control: study protocol for a longitudinal, open-label randomized controlled trial by Keishi Soga, Michio Takahashi, Akari Uno, Takamitsu Sinada, Kentaro Oba, Keisei Kawashima, Yasuko Tatewaki, Taizen Nakase, Yasuyuki Taki

“…The effect of exercise on cognition will be analyzed by comparing the measured outcomes before and after the intervention. The associations among these outcomes will be assessed using a linear mixed model and structural equation modeling approaches. …”
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Influence of social support on the social adaptive behaviors of children with acute leukemia in China: the mediating role of family functioning by Shen Yuqing, Mo Lin, Yu Lu, Chen ZeFang, Liu Tao, Zeng Yan, Sabika

“…Conclusions The evidence provided by this study indicates that social support can positively predict social adaptive behaviors, family functioning can negatively predict social adaptive behaviors, and family functioning mediates the relationship between social support and social adaptive behaviors.This study attributes to the development of precise interventions for caregivers for socially adapted behaviours in children with acute leukaemia and has important implications for policy development to improve the social adaptation of children with leukaemia.…”
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The effects of frailty, mental health, and cardiac function on quality of life in patients undergoing transcatheter aortic valve replacement by Jinyao Wang, Jun Cui, Xuemei Yang, Shuangyan Tu, Ying Wang, Yan Jiang, Lihong Zhao, Mao Chen, Zhonglan Chen, Yun Bao

“…However, the relationships between frailty, mental health, cardiac function, and QoL in patients after TAVR have not been well-studied. …”
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Getting under the skin of the menopausal hot flush: a protocol to examine skin function and structure in symptomatic postmenopausal women by Kirsty A. Roberts, Kirsty A. Roberts, Abigail Doyle, Helen Jones, Helen Jones, David A. Low, David A. Low

“…The study adheres to The Declaration of Helsinki and is being conducted in accordance with the UK Policy Framework for Health and Social Care Research.DiscussionIdentifying functional and/or structural changes in skin blood vessels or sweat glands in women with hot flushes would increase our understanding of their cause(s) and side effects, and help to design effective treatments, including interventions that can manipulate the activity of the skin blood vessels and/or sweat glands via pharmacological or non-pharmacological methods. …”
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Assessing structure-function impacts on Vitellogenin by leveraging allelic variant found in honey bee subspecies Apis mellifera mellifera by Vilde Leipart, Oriol Gracia Carmona, Christine Orengo, Franca Fraternali, Gro V. Amdam

“…Despite its importance, information on Vg’s structure-function relationships is limited. Leveraging a unique dataset of 1,086 fully sequenced Vg alleles, we identify a population-specific 9-nucleotide deletion in a central Vg domain of the locally endangered A. m. mellifera subspecies. …”
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GsMTx-4 combined with exercise improves skeletal muscle structure and motor function in rats with spinal cord injury. by Xin Zhang, Xinyu Liu, Qianxi Li, Chenyu Li, Xinyan Li, Jinghua Qian, Jianjun Li, Xuemei Li

“…Exercise training is a conventional physical therapy after SCI, but exercise intervention alone may have limited efficacy in reducing secondary injury and promoting nerve regeneration and functional remodeling. …”
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